{ "uniprot_canonical_ac": "Q8MXQ3-1", "uniprot_ac": "Q8MXQ3", "uniprot_id": "TM260_DICDI", "mass": { "chemical_mass": 94520.0, "monoisotopic_mass": 94520.0 }, "refseq": { "ac": "XP_643478", "name": "transmembrane protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643478" }, "gene_names": [ { "name": "DDB_G0275853", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q8MXQ3", "id": "Q8MXQ3" } ], "protein_names": [ { "name": "Protein O-mannosyl-transferase tmem260", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q8MXQ3" }, { "name": "2.4.1.109", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q8MXQ3" }, { "name": "Transmembrane protein 260 homolog", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q8MXQ3" }, { "name": "transmembrane protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643478", "id": "XP_643478" } ], "function": [ { "annotation": "O-mannosyl-transferase that transfers mannosyl residues to the hydroxyl group of serine or threonine residues of proteins.", "evidence": [ { "database": "UniProtKB", "id": "Q8MXQ3", "url": "https://www.uniprot.org/uniprot/Q8MXQ3#function" }, { "database": "UniProtKB", "id": "Q9NX78", "url": "https://www.uniprot.org/uniprot/Q9NX78#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q8MXQ3", "url": "https://www.uniprot.org/uniprot/Q8MXQ3" } ], "common_name": "Dictyostelium discoideum" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprot/Q8MXQ3", "locus": {} } ], "crossref": [ { "id": "DDB_G0275853", "url": "", "database": "", "categories": [ "Organism-specific" ] }, { "id": "8620059", "url": "https://www.ncbi.nlm.nih.gov/gene/8620059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ddi:DDB_G0275853", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0275853", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HSVNLMC", "url": "https://omabrowser.org/oma/group/HSVNLMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16214:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16214:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11028", "url": "http://pfam.xfam.org/family/PF11028", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q8MXQ3", "url": "http://purl.obolibrary.org/obo/PR_Q8MXQ3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_643478", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643478", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17377", "url": "https://www.rhea-db.org/rhea/17377", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53396", "url": "https://www.rhea-db.org/rhea/53396", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q8MXQ3", "url": "https://www.uniprot.org/uniprot/Q8MXQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8MXQ3-1", "url": "https://www.uniprot.org/uniprot/Q8MXQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNSPTLSNTRNRKNNNNNSNSNSNSNNNNNNNNNNNNNSNNNNNNNNNVNRNVNNRNNNNNNIINVNNNVSSTTMNMAKDFMNWNDGIIEREDTQLQQQKDRCFKILKKSTIACIVLLFISCTIIYSMTQYPSVSGGDAGELIVVAHQFGVAHPPGYPLFTFLGYIFSHIIPSNTLSVAWKISFMSSMIGSIASIFIYLTVYLWVNNHWCGLLSAYMFTFSPLIWMYQIQGEVFSMNNMFVAMLMFLGVWYTRVRIFENERYNTAFWTSERIAYLSAFSCAIGLTNQHTLVLIVIPFAFWLMFISGRDQLWNIKILSNLVFYTLIGLSPYLLLFITPKLNRVKYSWGNTSTLRGFIKHFLREEYGTLQLYGGDGGVISLFTKISIYIENLIIQFGYIGLALSLIGLLNLLLGYNIRTFKWKSFGTMIIFSFLFYITFFFNLCNLPIDKPLYRGVFLRFFMQPNVIISITMGLGIKSIFGFLNRIQRDGGTAATTTTTISKIQKYLLPIIIILLVGNQIGFNYNLQDQSDNYSFYDYGHSVLDGLPRNTLLLVGGDLVTNVPMYLHLCEKVRPDIDILSMEIMSWEWFKITQSPLFQRVKFPGNVYHPYIPDGYSLKDFLDANINDRPIYIGGDFKSGDSSFQNDYYTISKGLTSQIIPKKDSHKFNTFKIIKTTFSTFPSFHIPNNTEKYPNDSWEHFMMEEMAVSLERAAETLLKEYLSQQNTESFKALELSVEILEKALTYVNDKCWSLKHLGICFDHLRYRVVQNVNNNNQQAQNKASNYSKQLLYFWKKYINQCTHEENTDQDWETIKKVIQLI", "length": 819, "header": "sp|Q8MXQ3-1|TM260_DICDI Isoform 1 of Protein O-mannosyl-transferase tmem260 OS=Dictyostelium discoideum OX=44689 GN= PE=3 SV=2 CANONICAL=Q8MXQ3-1" }, "isoforms": [ { "isoform_ac": "Q8MXQ3-1", "url": "", "sequence": { "sequence": "MNNSPTLSNTRNRKNNNNNSNSNSNSNNNNNNNNNNNNNSNNNNNNNNNVNRNVNNRNNNNNNIINVNNNVSSTTMNMAKDFMNWNDGIIEREDTQLQQQKDRCFKILKKSTIACIVLLFISCTIIYSMTQYPSVSGGDAGELIVVAHQFGVAHPPGYPLFTFLGYIFSHIIPSNTLSVAWKISFMSSMIGSIASIFIYLTVYLWVNNHWCGLLSAYMFTFSPLIWMYQIQGEVFSMNNMFVAMLMFLGVWYTRVRIFENERYNTAFWTSERIAYLSAFSCAIGLTNQHTLVLIVIPFAFWLMFISGRDQLWNIKILSNLVFYTLIGLSPYLLLFITPKLNRVKYSWGNTSTLRGFIKHFLREEYGTLQLYGGDGGVISLFTKISIYIENLIIQFGYIGLALSLIGLLNLLLGYNIRTFKWKSFGTMIIFSFLFYITFFFNLCNLPIDKPLYRGVFLRFFMQPNVIISITMGLGIKSIFGFLNRIQRDGGTAATTTTTISKIQKYLLPIIIILLVGNQIGFNYNLQDQSDNYSFYDYGHSVLDGLPRNTLLLVGGDLVTNVPMYLHLCEKVRPDIDILSMEIMSWEWFKITQSPLFQRVKFPGNVYHPYIPDGYSLKDFLDANINDRPIYIGGDFKSGDSSFQNDYYTISKGLTSQIIPKKDSHKFNTFKIIKTTFSTFPSFHIPNNTEKYPNDSWEHFMMEEMAVSLERAAETLLKEYLSQQNTESFKALELSVEILEKALTYVNDKCWSLKHLGICFDHLRYRVVQNVNNNNQQAQNKASNYSKQLLYFWKKYINQCTHEENTDQDWETIKKVIQLI", "length": 819, "header": "sp|Q8MXQ3-1|TM260_DICDI Isoform 1 of Protein O-mannosyl-transferase tmem260 OS=Dictyostelium discoideum OX=44689 GN= PE=3 SV=2 CANONICAL=Q8MXQ3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 18, "start_aa": "Asn", "end_pos": 18, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn18", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 349, "start_aa": "Asn", "end_pos": 349, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn349", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 38, "start_aa": "Asn", "end_pos": 38, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn38", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 531, "start_aa": "Asn", "end_pos": 531, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn531", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 686, "start_aa": "Asn", "end_pos": 686, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn686", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 693, "start_aa": "Asn", "end_pos": 693, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn693", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 70, "start_aa": "Asn", "end_pos": 70, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 783, "start_aa": "Asn", "end_pos": 783, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn783", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycosyltransferase-activity", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.", "journal": "Nature", "date": "2002", "authors": "Gloeckner G., Kumpf K., Lehmann R., Platzer M., Rosenthal A., Bankier A.T., Dear P.H., Szafranski K., Guigo R., Parra G., Noegel A.A., Glockner G., Tunggal B., Abril J.F., Cox E., Eichinger L., Quail M.A., Cox E.C., Baumgart C., Pachebat J.A.", "evidence": [ { "database": "UniProtKB", "id": "Q8MXQ3", "url": "https://www.uniprot.org/uniprot/Q8MXQ3" } ], "reference": [ { "type": "PubMed", "id": "12097910", "url": "https://glygen.org/publication/PubMed/12097910" } ] }, { "title": "The genome of the social amoeba Dictyostelium discoideum.", "journal": "Nature", "date": "2005", "authors": "Chen G., Gibbs R.A., Gloeckner G., Hernandez J., Johnson D., Knights A., Lehmann R., Loulseged H., Ma J., Muzny D.M., Oliver K., Platzer M., Rosenthal A., Saito T., Sodergren E., Steffen D., Sugano S., Walker D., Weinstock G., Lu M., Muzny D., Tanaka Y., Song J., Sodergren E.J., Xu Q., Bankier A.T., Barrell B.G., Williams J., Fey P., Nie X., Gibbs R., Dear P.H., Szafranski K., Davies R., Price C., James K., Noegel A.A., Glockner G., Cooper J., Morio T., Davis P., Williams J.G., Kay R.R., Cronin A., Schleicher M., Olsen R., Kummerfeld S., Sharp S., Hauser H., Weinstock G.M., White B., Quiles M., Rost R., Tunggal B., Pain A., Madan Babu M., Madera M., Rivero F., Saunders D., Eichinger L., Sanders M., Kohara Y., Chisholm R.L., Barrell B., Churcher C.M., Hamlin N., Rajandream M.A., Thangavelu M., Quail M.A., Anjard C., Cox E.C., Haydock S., Kuspa A., Loomis W.F., Shaulsky G., Sucgang R., Urushihara H., Bason N., Berriman M., Buchrieser C., Churcher C., Desany B., Farbrother P., Felder M., Gaudet P., Goodhead I., Hall N., Harper D., Hemphill L., James K.D., Just E., Kerhornou A., Konfortov B.A., Lindsay R., Mourier T., Mungall K., Mungall K.L., Pachebat J.A., Pilcher K., Rabbinowitsch E., Simmonds M., Simmonds M.N., Spiegler S., Tivey A., Wardroper A., Winckler T., Woodward J., Woodward J.R., van Driessche N.", "evidence": [ { "database": "UniProtKB", "id": "Q8MXQ3", "url": "https://www.uniprot.org/uniprot/Q8MXQ3" } ], "reference": [ { "type": "PubMed", "id": "15875012", "url": "https://glygen.org/publication/PubMed/15875012" } ] } ], "pathway": [ { "id": "ddi:DDB_G0275853", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0275853", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8MXQ3", "url": "https://www.uniprot.org/uniprot/Q8MXQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 686, "end_pos": 688, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17377", "name": "", "equation": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q99PR0-1", "Q14U74-1", "Q9UKY4-1", "Q9Y6A1-1", "Q5T4D3-1", "Q8IUR5-5", "Q8N394-1", "Q6ZXV5-1", "Q9NX78-1", "Q8R2R1-1", "Q8BGQ4-1", "Q8BG19-1", "Q8BRH0-1", "Q56A06-1", "Q3UV71-1", "Q8BMD6-1", "P31382-1", "P46971-1", "P33775-1", "P47190-1", "P52867-1", "P42934-1", "Q06644-1", "Q8MXQ3-1", "Q9W5D4-1", "Q7K4B6-1", "Q9V3X5-1", "Q9VF81-1", "Q9VQE9-1", "Q9VTK2-1" ], "evidence": [ { "id": "17377", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17377" } ] }, { "id": "53396", "name": "", "equation": "a dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a dolichyl phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q99PR0-1", "Q14U74-1", "Q9UKY4-1", "Q9Y6A1-1", "Q5T4D3-1", "Q8IUR5-5", "Q8N394-1", "Q6ZXV5-1", "Q9NX78-1", "Q8R2R1-1", "Q8BGQ4-1", "Q8BG19-1", "Q8BRH0-1", "Q56A06-1", "Q3UV71-1", "Q8BMD6-1", "P31382-1", "P46971-1", "P33775-1", "P47190-1", "P52867-1", "P42934-1", "Q06644-1", "Q8MXQ3-1", "Q9W5D4-1", "Q7K4B6-1", "Q9V3X5-1", "Q9VF81-1", "Q9VQE9-1", "Q9VTK2-1" ], "evidence": [ { "id": "53396", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53396" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P31382", "gene_name": "PMT2", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "P31382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31382" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "P31382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31382" } ] } ] }, { "uniprot_ac": "P33775", "gene_name": "PMT1", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "P33775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33775" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "P33775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33775" } ] } ] }, { "uniprot_ac": "P42934", "gene_name": "PMT6", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "P42934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42934" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "P42934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42934" } ] } ] }, { "uniprot_ac": "P46971", "gene_name": "PMT4", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "P46971", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46971" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "P46971", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46971" } ] } ] }, { "uniprot_ac": "P47190", "gene_name": "PMT3", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "P47190", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47190" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "P47190", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47190" } ] } ] }, { "uniprot_ac": "P52867", "gene_name": "PMT5", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "P52867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52867" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "P52867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52867" } ] } ] }, { "uniprot_ac": "Q06644", "gene_name": "PMT7", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q06644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06644" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q06644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06644" } ] } ] }, { "uniprot_ac": "Q14U74", "gene_name": "Pomt2", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q14U74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14U74" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q14U74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14U74" } ] } ] }, { "uniprot_ac": "Q3UV71", "gene_name": "Tmtc1", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q3UV71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UV71" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q3UV71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UV71" } ] } ] }, { "uniprot_ac": "Q56A06", "gene_name": "Tmtc2", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q56A06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56A06" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q56A06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56A06" } ] } ] }, { "uniprot_ac": "Q5T4D3", "gene_name": "TMTC4", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q5T4D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5T4D3" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q5T4D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5T4D3" } ] } ] }, { "uniprot_ac": "Q6ZXV5", "gene_name": "TMTC3", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q6ZXV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZXV5" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q6ZXV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZXV5" } ] } ] }, { "uniprot_ac": "Q7K4B6", "gene_name": "Tmtc3", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q7K4B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7K4B6" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q7K4B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7K4B6" } ] } ] }, { "uniprot_ac": "Q8BG19", "gene_name": "Tmtc4", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q8BG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BG19" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q8BG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BG19" } ] } ] }, { "uniprot_ac": "Q8BGQ4", "gene_name": "Pomt2", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q8BGQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGQ4" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q8BGQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGQ4" } ] } ] }, { "uniprot_ac": "Q8BMD6", "gene_name": "Tmem260", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q8BMD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BMD6" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q8BMD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BMD6" } ] } ] }, { "uniprot_ac": "Q8BRH0", "gene_name": "Tmtc3", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q8BRH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRH0" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q8BRH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRH0" } ] } ] }, { "uniprot_ac": "Q8IUR5", "gene_name": "TMTC1", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q8IUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IUR5" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q8IUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IUR5" } ] } ] }, { "uniprot_ac": "Q8MXQ3", "gene_name": "", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q8MXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MXQ3" } ] } ] }, { "uniprot_ac": "Q8N394", "gene_name": "TMTC2", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q8N394", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N394" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q8N394", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N394" } ] } ] }, { "uniprot_ac": "Q8R2R1", "gene_name": "Pomt1", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q8R2R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R2R1" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q8R2R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R2R1" } ] } ] }, { "uniprot_ac": "Q99PR0", "gene_name": "Pomt1", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q99PR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99PR0" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q99PR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99PR0" } ] } ] }, { "uniprot_ac": "Q9NX78", "gene_name": "TMEM260", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q9NX78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NX78" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q9NX78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NX78" } ] } ] }, { "uniprot_ac": "Q9UKY4", "gene_name": "POMT2", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q9UKY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKY4" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q9UKY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKY4" } ] } ] }, { "uniprot_ac": "Q9V3X5", "gene_name": "", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q9V3X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3X5" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q9V3X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3X5" } ] } ] }, { "uniprot_ac": "Q9VF81", "gene_name": "", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q9VF81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VF81" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q9VF81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VF81" } ] } ] }, { "uniprot_ac": "Q9VQE9", "gene_name": "", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q9VQE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VQE9" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q9VQE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VQE9" } ] } ] }, { "uniprot_ac": "Q9VTK2", "gene_name": "rt", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q9VTK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VTK2" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q9VTK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VTK2" } ] } ] }, { "uniprot_ac": "Q9W5D4", "gene_name": "tw", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q9W5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W5D4" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q9W5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W5D4" } ] } ] }, { "uniprot_ac": "Q9Y6A1", "gene_name": "POMT1", "activity": [ { "ec_number": "2.4.1.109", "activity": "a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+).", "evidence": [ { "id": "Q9Y6A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6A1" } ] }, { "ec_number": "2.4.1.109", "activity": "", "evidence": [ { "id": "Q9Y6A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6A1" } ] } ] } ], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 8 }, { "field": "total_sites", "count": 8 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 8 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 8 }, { "field": "total_sites", "count": 8 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 8 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }