{
    "uniprot_canonical_ac": "Q8IRG5-1",
    "uniprot_ac": "Q8IRG5",
    "uniprot_id": "Q8IRG5_DROME",
    "mass": {
        "chemical_mass": 50859.0,
        "monoisotopic_mass": 50859.0
    },
    "refseq": {
        "ac": "NP_001163325",
        "name": "uncharacterized protein, isoform E",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163325"
    },
    "gene_names": [
        {
            "name": "Dmel\\CG13937",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8IRG5",
            "id": "Q8IRG5"
        },
        {
            "name": "d4ST2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8IRG5",
            "id": "Q8IRG5"
        },
        {
            "name": "CG13937",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163325",
            "id": "NP_001163325"
        },
        {
            "name": "CG13937",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8IRG5",
            "id": "Q8IRG5"
        },
        {
            "name": "Dmel\\CG13937",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8IRG5",
            "id": "Q8IRG5"
        },
        {
            "name": "Dmel_CG13937",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8IRG5",
            "id": "Q8IRG5"
        },
        {
            "name": "d4ST2; Dmel\\CG13937",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163325",
            "id": "NP_001163325"
        },
        {
            "name": "d4ST2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8IRG5",
            "id": "Q8IRG5"
        }
    ],
    "protein_names": [
        {
            "name": "Carbohydrate sulfotransferase",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8IRG5"
        },
        {
            "name": "2.8.2.-",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8IRG5"
        },
        {
            "name": "CG13937-PE",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163325",
            "id": "NP_001163325"
        },
        {
            "name": "CG13937-PG",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728688",
            "id": "NP_728688"
        },
        {
            "name": "CG13937-PH",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261297",
            "id": "NP_001261297"
        },
        {
            "name": "uncharacterized protein, isoform E",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163325",
            "id": "NP_001163325"
        },
        {
            "name": "uncharacterized protein, isoform G",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728688",
            "id": "NP_728688"
        },
        {
            "name": "uncharacterized protein, isoform H",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261297",
            "id": "NP_001261297"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0060283",
            "recommended_name": {
                "id": "DOID:0060283",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060283",
                "name": "peeling skin syndrome",
                "description": "A skin disease that is characterized by the painless peeling of the top layer of skin predominately on the hands and feet, has_material_basis_in autosomal recessive inheritance of mutation in the TGM5 gene and/pr CSTA gene."
            },
            "synonyms": [
                {
                    "id": "MONDO:0013124",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013124",
                    "name": "pelvic organ prolapse, susceptibility to, 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0013124",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013124",
                    "name": "pelvic organ prolapse, susceptibility to, 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0013124",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013124",
                    "name": "pelvic organ prolapse, susceptibility to, type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0013124",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013124",
                    "name": "Pvop2",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "peeling skin syndrome 1",
                    "description": "Any peeling skin syndrome in which the cause of the disease is a mutation in the CDSN gene."
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "CDSN peeling skin syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "PSS type B",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "generalised deciduous skin type B",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "generalised peeling skin syndrome type B",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "generalized deciduous skin type B",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "generalized peeling skin syndrome type B",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "inflammatory peeling skin syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "peeling skin syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "peeling skin syndrome caused by mutation in CDSN",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "peeling skin syndrome type B",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "PSS",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "PSS1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "deciduous skin",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "keratolysis exfoliativa congenita",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "skin peeling, familial continuous generalised",
                    "description": ""
                },
                {
                    "id": "MONDO:0024548",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024548",
                    "name": "skin peeling, familial continuous generalized",
                    "description": ""
                },
                {
                    "id": "MIM:270300",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/270300",
                    "name": "Peeling skin syndrome 1",
                    "description": "Peeling skin syndrome 1"
                }
            ],
            "evidence": [
                {
                    "id": "0060283",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060283"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8IRG5",
                    "url": "https://www.uniprot.org/uniprot/Q8IRG5"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "d4ST2",
            "url": "https://www.uniprot.org/uniprot/Q8IRG5",
            "locus": {
                "chromosome": "3L",
                "start_pos": 1876551,
                "end_pos": 1883041,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0035287",
                        "url": "https://www.ensembl.org/id/FBgn0035287"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0035287",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0035287",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "FBgn0035287",
            "url": "https://flybase.org/reports/FBgn0035287",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "38249",
            "url": "https://www.ncbi.nlm.nih.gov/gene/38249",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q8IRG5",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q8IRG5*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR005331",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005331",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018011",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018011",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG13937",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG13937",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "RWLLCQW",
            "url": "https://omabrowser.org/oma/group/RWLLCQW/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5394843at2759",
            "url": "http://www.orthodb.org/?query=5394843at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12137",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12137",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12137:SF63",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12137:SF63",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF03567",
            "url": "http://pfam.xfam.org/family/PF03567",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-2022870",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2022870",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-975578",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975578",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_728688",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728688",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "M9PBI7",
            "url": "https://www.uniprot.org/uniprot/M9PBI7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "M9PBI7-1",
            "url": "https://www.uniprot.org/uniprot/M9PBI7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8IRG5",
            "url": "https://www.uniprot.org/uniprot/Q8IRG5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8IRG5-1",
            "url": "https://www.uniprot.org/uniprot/Q8IRG5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9W070",
            "url": "https://www.uniprot.org/uniprot/Q9W070",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9W070-1",
            "url": "https://www.uniprot.org/uniprot/Q9W070-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MKLSKSLANCRAIRRYLLIFTAVSLLLLPLSLAYLVWNEQLQKIRGFEAFNVQQQSPQQPQPQQQQQEQQQQPQQHGQFPYPVVRYPVLLLNKNKNKDLTVVATGKTKNKWRYVDKDSNQTLLPLIPEHAVQTLTPQEMLQVEQRMDQRRERLKDKCSAYGLDVLGHDAWHTPNTWEFLVNKKYHIIWCNVFKAASSSWMFNFNVLAGYSPSYLRKTKKILLNLARERYPRVTLDELREAQNYSVTFIIARDPFERLLSAYRDKMVFALPYSFHDKLGRSIVRNYRKKPSLAARAANTKFPSFPEFVHWLLDQVKRGSFIDMHFVAATSFCTPCLIRFDMILKFESLAEDQLYLIEKTGLKRVIAPVWRNMGKGRKTHELQQQFYAQLTRQEMLELYEYYKYDFELFDYDIQEYLQVARPDEAESPAGTKN",
        "length": 431,
        "header": "tr|Q8IRG5-1|Q8IRG5_DROME Isoform 1 of Carbohydrate sulfotransferase  OS=Drosophila melanogaster OX=7227 GN=d4ST2 PE=2 SV=2 CANONICAL=Q8IRG5-1"
    },
    "isoforms": [
        {
            "isoform_ac": "M9PBI7-1",
            "url": "",
            "sequence": {
                "sequence": "MKLSKSLANCRAIRRYLLIFTAVSLLLLPLSLAYLVWNEQLQKIRGFEQQSPQQPQPQQQQQEQQQQPQQHGQFPYPVVRYPVLLLNKNKNKDLTVVATGKTKNKWRYVDKDSNQTLLPLIPEHAVQTLTPQEMLQVEQRMDQRRERLKDKCSAYGLDVLGHDAWHTPNTWEFLVNKKYHIIWCNVFKAASSSWMFNFNVLAGYSPSYLRKTKKILLNLARERYPRVTLDELREAQNYSVTFIIARDPFERLLSAYRDKMVFALPYSFHDKLGRSIVRNYRKKPSLAARAANTKFPSFPEFVHWLLDQVKRGSFIDMHFVAATSFCTPCLIRFDMILKFESLAEDQLYLIEKTGLKRVIAPVWRNMGKGRKTHELQQQFYAQLTRQEMLELYEYYKYDFELFDYDIQEYLQVARPDEAESPAGTKN",
                "length": 426,
                "header": "tr|M9PBI7-1|M9PBI7_DROME Computationally mapped isoform of Carbohydrate sulfotransferase  OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13937 PE=3 SV=1 CANONICAL=Q8IRG5-1"
            },
            "locus": {
                "chromosome": "3L",
                "start_pos": 1881272,
                "end_pos": 1876691,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0332669",
                        "url": "https://www.ensembl.org/id/FBtr0332669"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0304915",
                        "url": "https://www.ensembl.org/id/FBpp0304915"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8IRG5-1",
            "url": "",
            "sequence": {
                "sequence": "MKLSKSLANCRAIRRYLLIFTAVSLLLLPLSLAYLVWNEQLQKIRGFEAFNVQQQSPQQPQPQQQQQEQQQQPQQHGQFPYPVVRYPVLLLNKNKNKDLTVVATGKTKNKWRYVDKDSNQTLLPLIPEHAVQTLTPQEMLQVEQRMDQRRERLKDKCSAYGLDVLGHDAWHTPNTWEFLVNKKYHIIWCNVFKAASSSWMFNFNVLAGYSPSYLRKTKKILLNLARERYPRVTLDELREAQNYSVTFIIARDPFERLLSAYRDKMVFALPYSFHDKLGRSIVRNYRKKPSLAARAANTKFPSFPEFVHWLLDQVKRGSFIDMHFVAATSFCTPCLIRFDMILKFESLAEDQLYLIEKTGLKRVIAPVWRNMGKGRKTHELQQQFYAQLTRQEMLELYEYYKYDFELFDYDIQEYLQVARPDEAESPAGTKN",
                "length": 431,
                "header": "tr|Q8IRG5-1|Q8IRG5_DROME Isoform 1 of Carbohydrate sulfotransferase  OS=Drosophila melanogaster OX=7227 GN=d4ST2 PE=2 SV=2 CANONICAL=Q8IRG5-1"
            },
            "locus": {
                "chromosome": "3L",
                "start_pos": 1881272,
                "end_pos": 1876691,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0300716",
                        "url": "https://www.ensembl.org/id/FBtr0300716"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0289940",
                        "url": "https://www.ensembl.org/id/FBpp0289940"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9W070-1",
            "url": "",
            "sequence": {
                "sequence": "MKLSKSLANCRAIRRYLLIFTAVSLLLLPLSLAYLVWNEQLQKIRGFEDSNQTLLPLIPEHAVQTLTPQEMLQVEQRMDQRRERLKDKCSAYGLDVLGHDAWHTPNTWEFLVNKKYHIIWCNVFKAASSSWMFNFNVLAGYSPSYLRKTKKILLNLARERYPRVTLDELREAQNYSVTFIIARDPFERLLSAYRDKMVFALPYSFHDKLGRSIVRNYRKKPSLAARAANTKFPSFPEFVHWLLDQVKRGSFIDMHFVAATSFCTPCLIRFDMILKFESLAEDQLYLIEKTGLKRVIAPVWRNMGKGRKTHELQQQFYAQLTRQEMLELYEYYKYDFELFDYDIQEYLQVARPDEAESPAGTKN",
                "length": 363,
                "header": "tr|Q9W070-1|Q8IRG5_DROME Computationally mapped isoform of Carbohydrate sulfotransferase  OS=Drosophila melanogaster OX=7227 GN=d4ST2 PE=2 SV=3 CANONICAL=Q8IRG5-1"
            },
            "locus": {
                "chromosome": "3L",
                "start_pos": 1881272,
                "end_pos": 1876691,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0300714",
                        "url": "https://www.ensembl.org/id/FBtr0300714"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0289938",
                        "url": "https://www.ensembl.org/id/FBpp0289938"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [
        {
            "title": "The genome sequence of Drosophila melanogaster.",
            "journal": "Science",
            "date": "2000",
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