{
    "uniprot_canonical_ac": "Q8CG85-1",
    "uniprot_ac": "Q8CG85",
    "uniprot_id": "MAMC2_MOUSE",
    "mass": {
        "chemical_mass": 77324.0,
        "monoisotopic_mass": 77324.0
    },
    "refseq": {
        "ac": "NP_777282",
        "name": "MAM domain-containing protein 2 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777282"
    },
    "gene_names": [
        {
            "name": "Mamdc2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8CG85",
            "id": "Q8CG85"
        },
        {
            "name": "1200015L10Rik; mamcan",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777282",
            "id": "NP_777282"
        },
        {
            "name": "Mamdc2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777282",
            "id": "NP_777282"
        }
    ],
    "protein_names": [
        {
            "name": "MAM domain-containing protein 2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8CG85"
        },
        {
            "name": "MAM domain-containing protein 2 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777282",
            "id": "NP_777282"
        },
        {
            "name": "MAM domain-containing protein 2; MAM domain-containing proteoglycan",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777282",
            "id": "NP_777282"
        },
        {
            "name": "MAM domain-containing proteoglycan",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8CG85"
        },
        {
            "name": "Mamcan",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8CG85"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CG85",
                    "url": "https://www.uniprot.org/uniprot/Q8CG85"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Mamdc2",
            "url": "https://www.uniprot.org/uniprot/Q8CG85",
            "locus": {
                "chromosome": "19",
                "start_pos": 23279973,
                "end_pos": 23425806,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000033207",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000033207"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000033207",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000033207",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd06263",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "71738",
            "url": "https://www.ncbi.nlm.nih.gov/gene/71738",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000998",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013320",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:71738",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:71738",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1918988",
            "url": "http://www.informatics.jax.org/marker/MGI:1918988",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "QSVSWMR",
            "url": "https://omabrowser.org/oma/group/QSVSWMR/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3037322at2759",
            "url": "http://www.orthodb.org/?query=3037322at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23282",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23282:SF101",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282:SF101",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23282:SF141",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282:SF141",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00629",
            "url": "http://pfam.xfam.org/family/PF00629",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8CG85",
            "url": "http://purl.obolibrary.org/obo/PR_Q8CG85",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_777282",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777282",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4J0J7",
            "url": "https://www.uniprot.org/uniprot/A0A0R4J0J7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4J0J7-1",
            "url": "https://www.uniprot.org/uniprot/A0A0R4J0J7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A494B959",
            "url": "https://www.uniprot.org/uniprot/A0A494B959",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A494B959-1",
            "url": "https://www.uniprot.org/uniprot/A0A494B959-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CG85",
            "url": "https://www.uniprot.org/uniprot/Q8CG85",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CG85-1",
            "url": "https://www.uniprot.org/uniprot/Q8CG85-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MLLEGVLLVVQALQLASALDLPAGSCAFEEDTCGFDSVFAFLPWILNEEGHYVYMDTSFARQGEKAVLLSSDLQAEEWNCLRLVYQITTPPGSVSDPSQLNLYVRFEDESFDRLLWSTKEPSDSWLIASLDLQNTSKKFKILIEGVLGQGNTASIALFEIKMTAGYCIECDFEENHLCGFVNRWNPNVNWFVGGGTAKNTHSVLPQDHTFRSEHGHYMYVDSVYVKHFQEVAQLISPVTTASMSGCLSFYYQLQQGNDNVFSVYTRDMAGLYEEIWKVDSPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTGLPFSAVETSCDFEIGLCNFYQDKEGPGWTRVRVKANMYRAGDHTTGTGHYLLANTKFTSQPGYIGRLYGPSLPGNMQYCVRFHYAIFGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEISFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGNCRSPARLPPPPGECTFDQDECAFTQEKRNRSSWHRGRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCLTFFYHMYGAGTGLLSVYLKREEDSEESLLWRRRGEQSISWLRALVEYSCRRRHQIIFEATRGVSIRSDIAIDDVKLQAGPCAGMEDTTEQSSGYSEDLNEIEY",
        "length": 686,
        "header": "sp|Q8CG85-1|MAMC2_MOUSE Isoform 1 of MAM domain-containing protein 2  OS=Mus musculus OX=10090 GN=Mamdc2 PE=1 SV=1 CANONICAL=Q8CG85-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0R4J0J7-1",
            "url": "",
            "sequence": {
                "sequence": "MLLEGVLLVVQALQLANALDLPAGSCAFEEDTCGFDSVFAFLPWILNEEGHYVYMDTSFARQGEKAVLLSSDLQAEEWNCLRLVYQITTPPGSVSDPSQLNLYVRFEDESFDRLLWSTKEPSDSWLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKMTAGYCIECDFEENHLCGFVNRWNPNVNWFVGGGTAKNTHSILPQDHTFRSEHGHYMYVDSVYVKHFQEVAQLISPVTTASMSGCLSFYYQLQQGNDNVFSVYTRDMAGLYEEIWKVDSPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTGLPFSAVETSCDFEIGLCNFYQDKEGPGWTRVRVKANMYRAGDHTTGTGHYLLANTKFTSQPGYIGRLYGPSLPGNMQYCVRFHYAIFGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEISFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGNCRSPARLPPPPGECTFDQDECAFTQEKRNRSSWHRGRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCLTFFYHMYGAGTGLLSVYLKREEDSEESLLWRRRGEQSISWLRALVEYSCRRRHQIIFEATRGVSIRSDIAIDDVKLQAGPCAGMEDTTEQSSGYSEDLNEIEY",
                "length": 686,
                "header": "tr|A0A0R4J0J7-1|A0A0R4J0J7_MOUSE Computationally mapped isoform of MAM domain containing 2  OS=Mus musculus OX=10090 GN=Mamdc2 PE=1 SV=1 CANONICAL=Q8CG85-1"
            },
            "locus": {
                "chromosome": "19",
                "start_pos": 23425422,
                "end_pos": 23280989,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000036069.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000036069.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000045432.7",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000045432.7"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A494B959-1",
            "url": "",
            "sequence": {
                "sequence": "MLLEGVLLVVQALQLANALDLPAGSCAFEEDTCGFDSVFAFLPWILNEEGHYVYMDTSFARQGEKAVLLSSDLQAEEWNCLRLVYQITTPPGSVSDPSQLNLYVRFEDESFDRLLWSTKEPSDSWLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKMTAGYCIECDFEENHLCGFVNRWNPNVNWFVGGGTAKNTHSILPQDHTFRSEHGYF",
                "length": 217,
                "header": "tr|A0A494B959-1|A0A494B959_MOUSE Computationally mapped isoform of MAM domain containing 2  OS=Mus musculus OX=10090 GN=Mamdc2 PE=1 SV=1 CANONICAL=Q8CG85-1"
            },
            "locus": {
                "chromosome": "19",
                "start_pos": 23425422,
                "end_pos": 23336600,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000236349.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000236349.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000157505.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000157505.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8CG85-1",
            "url": "",
            "sequence": {
                "sequence": "MLLEGVLLVVQALQLASALDLPAGSCAFEEDTCGFDSVFAFLPWILNEEGHYVYMDTSFARQGEKAVLLSSDLQAEEWNCLRLVYQITTPPGSVSDPSQLNLYVRFEDESFDRLLWSTKEPSDSWLIASLDLQNTSKKFKILIEGVLGQGNTASIALFEIKMTAGYCIECDFEENHLCGFVNRWNPNVNWFVGGGTAKNTHSVLPQDHTFRSEHGHYMYVDSVYVKHFQEVAQLISPVTTASMSGCLSFYYQLQQGNDNVFSVYTRDMAGLYEEIWKVDSPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTGLPFSAVETSCDFEIGLCNFYQDKEGPGWTRVRVKANMYRAGDHTTGTGHYLLANTKFTSQPGYIGRLYGPSLPGNMQYCVRFHYAIFGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEISFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGNCRSPARLPPPPGECTFDQDECAFTQEKRNRSSWHRGRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCLTFFYHMYGAGTGLLSVYLKREEDSEESLLWRRRGEQSISWLRALVEYSCRRRHQIIFEATRGVSIRSDIAIDDVKLQAGPCAGMEDTTEQSSGYSEDLNEIEY",
                "length": 686,
                "header": "sp|Q8CG85-1|MAMC2_MOUSE Isoform 1 of MAM domain-containing protein 2  OS=Mus musculus OX=10090 GN=Mamdc2 PE=1 SV=1 CANONICAL=Q8CG85-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 134,
            "start_aa": "Asn",
            "end_pos": 134,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn134",
            "evidence": [
                {
                    "id": "Q8CG85",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8CG85#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 329,
            "start_aa": "Asn",
            "end_pos": 329,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn329",
            "evidence": [
                {
                    "id": "Q8CG85",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8CG85#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 524,
            "start_aa": "Asn",
            "end_pos": 524,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn524",
            "evidence": [
                {
                    "id": "Q8CG85",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8CG85#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Transcriptome-based systematic identification of extracellular matrix proteins.",
            "journal": "Proc. Natl. Acad. Sci. U.S.A.",
            "date": "2008",
            "authors": "Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CG85",
                    "url": "https://www.uniprot.org/uniprot/Q8CG85"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18757743",
                    "url": "https://glygen.org/publication/PubMed/18757743"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:71738",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:71738",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CG85",
                                "url": "https://www.uniprot.org/uniprot/Q8CG85"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endoplasmic reticulum",
                        "id": "GO:0005783",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CG85",
                                "url": "https://www.uniprot.org/uniprot/Q8CG85"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "extracellular region",
                        "id": "GO:0005576",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CG85",
                                "url": "https://www.uniprot.org/uniprot/Q8CG85"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "extracellular matrix",
                        "id": "GO:0031012",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CG85",
                                "url": "https://www.uniprot.org/uniprot/Q8CG85"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "interstitial matrix",
                        "id": "GO:0005614",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CG85",
                                "url": "https://www.uniprot.org/uniprot/Q8CG85"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "nervous system development",
                        "id": "GO:0007399",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CG85",
                                "url": "https://www.uniprot.org/uniprot/Q8CG85"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan",
                        "id": "GO:0019800",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019800",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CG85",
                                "url": "https://www.uniprot.org/uniprot/Q8CG85"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "glycosaminoglycan binding",
                        "id": "GO:0005539",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005539",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CG85",
                                "url": "https://www.uniprot.org/uniprot/Q8CG85"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 134,
            "end_pos": 136,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 329,
            "end_pos": 331,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 524,
            "end_pos": 526,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "O-glycosylated; contains chondroitin sulfate.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CG85",
                    "url": "https://www.uniprot.org/uniprot/Q8CG85"
                },
                {
                    "database": "PubMed",
                    "id": "18757743",
                    "url": "https://glygen.org/publication/PubMed/18757743"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 3
                },
                {
                    "field": "total_sites",
                    "count": 3
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 3
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
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