{
    "uniprot_canonical_ac": "Q8CFG9-1",
    "uniprot_ac": "Q8CFG9",
    "uniprot_id": "C1RB_MOUSE",
    "mass": {
        "chemical_mass": 79936.0,
        "monoisotopic_mass": 79936.0
    },
    "refseq": {
        "ac": "NP_001106827",
        "name": "complement C1r-B subcomponent precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106827"
    },
    "gene_names": [
        {
            "name": "C1rb",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8CFG9",
            "id": "Q8CFG9"
        },
        {
            "name": "667277; Gm8551; mC1rB",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106827",
            "id": "NP_001106827"
        },
        {
            "name": "C1rb",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106827",
            "id": "NP_001106827"
        },
        {
            "name": "C1r",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8CFG9",
            "id": "Q8CFG9"
        }
    ],
    "protein_names": [
        {
            "name": "Complement C1r-B subcomponent",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8CFG9"
        },
        {
            "name": "3.4.21.41",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8CFG9"
        },
        {
            "name": "Complement component 1 subcomponent r-B",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8CFG9"
        },
        {
            "name": "complement C1r-B subcomponent precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106827",
            "id": "NP_001106827"
        },
        {
            "name": "complement C1r-B subcomponent; complement component C1rb; complement component 1, r-B subcomponent; complement component 1 subcomponent r-B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106827",
            "id": "NP_001106827"
        }
    ],
    "function": [
        {
            "annotation": "C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CFG9",
                    "url": "https://www.uniprot.org/uniprot/Q8CFG9#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0080986",
            "recommended_name": {
                "id": "DOID:0080986",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080986",
                "name": "Ehlers-Danlos syndrome periodontal type 1",
                "description": "An Ehlers-Danlos syndrome that is characterized by an Ehlers-Danlos syndrome phenotype combined with severe periodontal inflammation and that has_material_basis_in heterozygous mutation in the C1R gene on chromosome 12p13."
            },
            "synonyms": [
                {
                    "id": "MONDO:0020684",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0020684",
                    "name": "Ehlers-Danlos syndrome, periodontal type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0020684",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0020684",
                    "name": "EDS 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0020684",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0020684",
                    "name": "EDSPD1",
                    "description": ""
                },
                {
                    "id": "MONDO:0020684",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0020684",
                    "name": "Ehlers-Danlos syndrome, periodontal type, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0020684",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0020684",
                    "name": "Ehlers-Danlos syndrome, periodontitis type",
                    "description": ""
                },
                {
                    "id": "MONDO:0020684",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0020684",
                    "name": "Ehlers-Danlos syndrome, periodontosis type",
                    "description": ""
                },
                {
                    "id": "MONDO:0020684",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0020684",
                    "name": "Ehlers-Danlos syndrome, type 8",
                    "description": ""
                },
                {
                    "id": "MIM:130080",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/130080",
                    "name": "Ehlers-Danlos syndrome, periodontal type, 1",
                    "description": "Ehlers-Danlos syndrome, periodontal type, 1"
                }
            ],
            "evidence": [
                {
                    "id": "0080986",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080986"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CFG9",
                    "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "C1rb",
            "url": "https://www.uniprot.org/uniprot/Q8CFG9",
            "locus": {
                "chromosome": "6",
                "start_pos": 124558130,
                "end_pos": 124547253,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000098470",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000098470"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000098470",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000098470",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00033",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd00041",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd00054",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd00190",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "667277",
            "url": "https://www.ncbi.nlm.nih.gov/gene/667277",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000436",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR000742",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR000859",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001254",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001314",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001881",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR009003",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018097",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR024175",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR024175",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR033116",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR035914",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR035976",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR043504",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:667277",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:667277",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "3779804",
            "url": "http://www.informatics.jax.org/marker/MGI:3779804",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "IIWFLWF",
            "url": "https://omabrowser.org/oma/group/IIWFLWF/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5394076at2759",
            "url": "http://www.orthodb.org/?query=5394076at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24255",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24255",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24255:SF25",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24255:SF25",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00084",
            "url": "http://pfam.xfam.org/family/PF00084",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00089",
            "url": "http://pfam.xfam.org/family/PF00089",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00431",
            "url": "http://pfam.xfam.org/family/PF00431",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF14670",
            "url": "http://pfam.xfam.org/family/PF14670",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8CFG9",
            "url": "http://purl.obolibrary.org/obo/PR_Q8CFG9",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001106827",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106827",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CFG9",
            "url": "https://www.uniprot.org/uniprot/Q8CFG9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CFG9-1",
            "url": "https://www.uniprot.org/uniprot/Q8CFG9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MWLFALLVTLFYGVEGSIYLPQKLYGEVTSPLYPKPYPSDLETTTVITVPMGYRVKLVFWQFDVEPSEGCLYDYVKISADKQTLGRFCGQLDSPLGNPPGSKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASQPNSVEEGLQPRCQHLCHNYVGGYFCSCHPGYELQKDGQSCQAECSSELYTEPSGYVSSLEYPQPYPPDLRCNYSIRVERGLTVHLKFLDPFEIDDHQQVHCPYDQLQIYANGKNLGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLHYTTETIKCPQPKALDEFTIIQDPQPQYQFRDYFTVTCKQGYQLMEGNQALLSFTAVCQHDGTWHRAMPRCKIKNCGQPQSLSNGDFRYITTKGVTTYEASIQYHCHEPYYKMLTRAGSSESMRGIYTCTAQGIWKNEEEGEKMPRCLPVCGKPVNPVTQKERIIGGQPARPGNFPWQAFTTIYGPGGGALLGDRWILTAAHTIYPKYPNKGKNTNPRTLVFLGHTNMEQIQKLGHHPVRRVIIHPDYRQEEPDNFEGDIALLELENSVTLGPELLPICLPDNETFYGQGLMGYVSGFGTTGNRIPFHLRFVRLPVADREACQRWLWTKKDTSPFSQNMFCSGDPAVQQDACQGDSGGVFAVRDRNRDIWVATGIVSWGIGCGEGYGFYTKVLNYVDWIKKEMGDEN",
        "length": 706,
        "header": "sp|Q8CFG9-1|C1RB_MOUSE Isoform 1 of Complement C1r-B subcomponent  OS=Mus musculus OX=10090 GN=C1rb PE=2 SV=1 CANONICAL=Q8CFG9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q8CFG9-1",
            "url": "",
            "sequence": {
                "sequence": "MWLFALLVTLFYGVEGSIYLPQKLYGEVTSPLYPKPYPSDLETTTVITVPMGYRVKLVFWQFDVEPSEGCLYDYVKISADKQTLGRFCGQLDSPLGNPPGSKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASQPNSVEEGLQPRCQHLCHNYVGGYFCSCHPGYELQKDGQSCQAECSSELYTEPSGYVSSLEYPQPYPPDLRCNYSIRVERGLTVHLKFLDPFEIDDHQQVHCPYDQLQIYANGKNLGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLHYTTETIKCPQPKALDEFTIIQDPQPQYQFRDYFTVTCKQGYQLMEGNQALLSFTAVCQHDGTWHRAMPRCKIKNCGQPQSLSNGDFRYITTKGVTTYEASIQYHCHEPYYKMLTRAGSSESMRGIYTCTAQGIWKNEEEGEKMPRCLPVCGKPVNPVTQKERIIGGQPARPGNFPWQAFTTIYGPGGGALLGDRWILTAAHTIYPKYPNKGKNTNPRTLVFLGHTNMEQIQKLGHHPVRRVIIHPDYRQEEPDNFEGDIALLELENSVTLGPELLPICLPDNETFYGQGLMGYVSGFGTTGNRIPFHLRFVRLPVADREACQRWLWTKKDTSPFSQNMFCSGDPAVQQDACQGDSGGVFAVRDRNRDIWVATGIVSWGIGCGEGYGFYTKVLNYVDWIKKEMGDEN",
                "length": 706,
                "header": "sp|Q8CFG9-1|C1RB_MOUSE Isoform 1 of Complement C1r-B subcomponent  OS=Mus musculus OX=10090 GN=C1rb PE=2 SV=1 CANONICAL=Q8CFG9-1"
            },
            "locus": {
                "chromosome": "6",
                "start_pos": 124557982,
                "end_pos": 124547416,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000184647",
                        "url": "https://www.ensembl.org/id/ENSMUST00000184647"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000139376",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000139376"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 124,
            "start_aa": "Asn",
            "end_pos": 124,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn124",
            "evidence": [
                {
                    "id": "Q8CFG9",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8CFG9#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 220,
            "start_aa": "Asn",
            "end_pos": 220,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn220",
            "evidence": [
                {
                    "id": "Q8CFG9",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8CFG9#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 582,
            "start_aa": "Asn",
            "end_pos": 582,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn582",
            "evidence": [
                {
                    "id": "Q8CFG9",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8CFG9#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 205,
            "end_pos": 205,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine; by CK2",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CFG9",
                    "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                }
            ],
            "site_lbl": "Ser205"
        }
    ],
    "glycation": [],
    "keywords": [
        "enzyme",
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Complement C1r and C1s genes are duplicated in the mouse: differential expression generates alternative isomorphs in the liver and in the male reproductive system.",
            "journal": "Biochem. J.",
            "date": "2003",
            "authors": "Garnier G, Circolo A, Xu Y, Volanakis JE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CFG9",
                    "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12513694",
                    "url": "https://glygen.org/publication/PubMed/12513694"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:667277",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:667277",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "B5DEH7-1",
            "protein_name": "Complement C1r",
            "gene_name": "C1r",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MRLIPLLLVTLFCGVEGSIYLPQKLYGEVTSPLYPKPYPSDLETTTVITVPTGYRVKLVFWQFDVEPSEGCFYDYVKISADKKTLGRFCGQQDSPQGNPPGRKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECTSQPNSVEEGLQPRCQHLCHNYVGGYFCSCRPGYELQKDRQSCQAECSSGLYTEPSGYISSLEYPKPYPPDLRCNYSIRVERGLTVHLKFLDPFEIDDHQQVHCPYDQLQIYANGKNLGEFCGTQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKALDEFTIIQDPQPQYQFRDYFIVTCKQGYQLMEGSQALLSFTAVCQHDGTWHRAMPRCKIKDCGQPRSLSNGDFRYLTTRGVNTYEARIQYYCHDPYYKMMTRAGSSESVRGIYTCTPQGIWKNEEEGEKMPRCLPVCGKPVNPVTQKQRIIGGQKANPGNFPWQAFTNIHGRGGGALLGDRWILTAAHTIYPKEHNKENNVNVSKDVFLGHTNVEEIKKLGHHPVRRVIIHPDYRQDEPNNFEGDIALLELENSVTLGPNLLPICLPDNETFYDKDLMGYVSGFGITEDKIAFNLRFVRLPIADREACQRWLRTKNSNDVFSQNMFCSGDPTLKHDACQGDSGGVFAVRDRSRDIWVATGIVSWGIGCGEGYGFYTKLLNYVDWIKKEIGDEN",
                "length": 707
            },
            "evidence": [
                {
                    "id": "45239035",
                    "url": "http://www.informatics.jax.org/homology/45239035",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "P00736-1",
            "protein_name": "Complement C1r subcomponent",
            "gene_name": "C1R",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MWLLYLLVPALFCRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIKKEMEEED",
                "length": 705
            },
            "evidence": [
                {
                    "id": "45239035",
                    "url": "http://www.informatics.jax.org/homology/45239035",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 4,
                "go_terms": [
                    {
                        "name": "serine-type endopeptidase activity",
                        "id": "GO:0004252",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "identical protein binding",
                        "id": "GO:0042802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "calcium ion binding",
                        "id": "GO:0005509",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "molecular sequestering activity",
                        "id": "GO:0140313",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140313",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "extracellular region",
                        "id": "GO:0005576",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "extracellular space",
                        "id": "GO:0005615",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "complement component C1 complex",
                        "id": "GO:0005602",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005602",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "innate immune response",
                        "id": "GO:0045087",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "zymogen activation",
                        "id": "GO:0031638",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031638",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "complement activation, classical pathway",
                        "id": "GO:0006958",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CFG9",
                                "url": "https://www.uniprot.org/uniprot/Q8CFG9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 124,
            "end_pos": 126,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 220,
            "end_pos": 222,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 582,
            "end_pos": 584,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 3
                },
                {
                    "field": "total_sites",
                    "count": 3
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 3
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
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                "type",
                "subtype",
                "site_category",
                "site_seq",
                "relation",
                "comment",
                "start_pos",
                "start_aa",
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            ]
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
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                    "field": "total",
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                },
                {
                    "field": "total_sites",
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                },
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                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
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                    "field": "total",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
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                },
                {
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                {
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                },
                {
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                }
            ],
            "sort_fields": [
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            ]
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
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                    "field": "total",
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                {
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
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                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
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                }
            ],
            "sort_fields": [
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                "kinase_uniprot_canonical_ac",
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        },
        {
            "table_id": "snv",
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                {
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            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
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                    "field": "total",
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                {
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            ],
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        },
        {
            "table_id": "snv_non_disease",
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                {
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        {
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            ],
            "sort_fields": [
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        }
    ]
}