{
    "uniprot_canonical_ac": "Q8CEK7-1",
    "uniprot_ac": "Q8CEK7",
    "uniprot_id": "FATE1_MOUSE",
    "mass": {
        "chemical_mass": 11726.0,
        "monoisotopic_mass": 11726.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Fate1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8CEK7",
            "id": "Q8CEK7"
        },
        {
            "name": "Fate",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8CEK7",
            "id": "Q8CEK7"
        }
    ],
    "protein_names": [
        {
            "name": "Fetal and adult testis-expressed transcript protein homolog",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8CEK7"
        }
    ],
    "function": [
        {
            "annotation": "Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CEK7",
                    "url": "https://www.uniprot.org/uniprot/Q8CEK7#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q969F0",
                    "url": "https://www.uniprot.org/uniprot/Q969F0#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CEK7",
                    "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Fate1",
            "url": "https://www.uniprot.org/uniprot/Q8CEK7",
            "locus": {
                "chromosome": "X",
                "start_pos": 71032652,
                "end_pos": 71016592,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000053593",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000053593"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000053593",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000053593",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "IPR039153",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039153",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1925155",
            "url": "http://www.informatics.jax.org/marker/MGI:1925155",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "DQDATWR",
            "url": "https://omabrowser.org/oma/group/DQDATWR/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR21128",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21128",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR21128:SF0",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21128:SF0",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8CEK7",
            "url": "http://purl.obolibrary.org/obo/PR_Q8CEK7",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CEK7",
            "url": "https://www.uniprot.org/uniprot/Q8CEK7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CEK7-1",
            "url": "https://www.uniprot.org/uniprot/Q8CEK7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MPWVPREHSHDDVQLQEFSRNFPVGRFPYECLEADIMAKIGLEELNGLEMEVMRRQMQMTSGRLHILEDQDATWCHKEAALFTLLVSVCIANLWLWVHW",
        "length": 99,
        "header": "sp|Q8CEK7-1|FATE1_MOUSE Isoform 1 of Fetal and adult testis-expressed transcript protein homolog  OS=Mus musculus OX=10090 GN=Fate1 PE=3 SV=1 CANONICAL=Q8CEK7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q8CEK7-1",
            "url": "",
            "sequence": {
                "sequence": "MPWVPREHSHDDVQLQEFSRNFPVGRFPYECLEADIMAKIGLEELNGLEMEVMRRQMQMTSGRLHILEDQDATWCHKEAALFTLLVSVCIANLWLWVHW",
                "length": 99,
                "header": "sp|Q8CEK7-1|FATE1_MOUSE Isoform 1 of Fetal and adult testis-expressed transcript protein homolog  OS=Mus musculus OX=10090 GN=Fate1 PE=3 SV=1 CANONICAL=Q8CEK7-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 71032205,
                "end_pos": 71031256,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000114569",
                        "url": "https://www.ensembl.org/id/ENSMUST00000114569"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000110216",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000110216"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "negative regulation of mitochondrial calcium ion concentration",
                        "id": "GO:0051562",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051562",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CEK7",
                                "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of apoptotic process",
                        "id": "GO:0043066",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066",
                        "evidence": [
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                                "database": "UniProtKB",
                                "id": "Q8CEK7",
                                "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "apoptotic process",
                        "id": "GO:0006915",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CEK7",
                                "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "mitochondrial outer membrane",
                        "id": "GO:0005741",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CEK7",
                                "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endoplasmic reticulum",
                        "id": "GO:0005783",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CEK7",
                                "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endoplasmic reticulum membrane",
                        "id": "GO:0005789",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CEK7",
                                "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondria-associated endoplasmic reticulum membrane",
                        "id": "GO:0044233",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CEK7",
                                "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "identical protein binding",
                        "id": "GO:0042802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CEK7",
                                "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin protein ligase binding",
                        "id": "GO:0031625",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CEK7",
                                "url": "https://www.uniprot.org/uniprot/Q8CEK7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
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    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [],
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