{
    "uniprot_canonical_ac": "Q8CBF3-1",
    "uniprot_ac": "Q8CBF3",
    "uniprot_id": "EPHB1_MOUSE",
    "mass": {
        "chemical_mass": 109881.0,
        "monoisotopic_mass": 109881.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Ephb1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8CBF3",
            "id": "Q8CBF3"
        }
    ],
    "protein_names": [
        {
            "name": "Ephrin type-B receptor 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8CBF3"
        },
        {
            "name": "2.7.10.1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8CBF3"
        }
    ],
    "function": [
        {
            "annotation": "Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. In addition to its role in axon guidance also plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively. Involved in the maintenance of the pool of satellite cells (muscle stem cells) by promoting their self-renewal and reducing their activation and differentiation (PubMed:27446912).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3#function"
                },
                {
                    "database": "PubMed",
                    "id": "27446912",
                    "url": "https://glygen.org/publication/PubMed/27446912"
                },
                {
                    "database": "PubMed",
                    "id": "12971893",
                    "url": "https://glygen.org/publication/PubMed/12971893"
                },
                {
                    "database": "PubMed",
                    "id": "14691139",
                    "url": "https://glygen.org/publication/PubMed/14691139"
                },
                {
                    "database": "PubMed",
                    "id": "18524895",
                    "url": "https://glygen.org/publication/PubMed/18524895"
                },
                {
                    "database": "PubMed",
                    "id": "18057206",
                    "url": "https://glygen.org/publication/PubMed/18057206"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0080685",
            "recommended_name": {
                "id": "DOID:0080685",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080685",
                "name": "aortic dissection",
                "description": "An aortic disease that is characterized by tearing of the intimal layer of the aorta resulting in separation of the layers of the aortic wall."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0080685",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080685"
                }
            ]
        },
        {
            "disease_id": "DOID:10283",
            "recommended_name": {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10283",
                "name": "prostate cancer",
                "description": "A male reproductive organ cancer that is located_in the prostate."
            },
            "synonyms": [
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "NGP - new growth of prostate",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "hereditary prostate cancer",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "malignant tumor of the prostate",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostate cancer, familial",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostate neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostatic cancer",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostatic neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "tumor of the prostate",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, type 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "HPC9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, 12",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene."
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "EHBP1 familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "familial prostate cancer caused by mutation in EHBP1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, type 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "HPC12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, type 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "HPC5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, susceptibility to, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "HPC3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, susceptibility to, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "HPC4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, on chromosome 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, 13",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene."
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "MSMB familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "familial prostate cancer caused by mutation in MSMB",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, type 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "HPC13",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, type 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "HPC8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "predisposing for prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, type 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "HPC6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "prostate cancer, hereditary, 10",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "HPC10",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "prostate cancer, hereditary, 10",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "familial prostate carcinoma",
                    "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma."
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "hereditary prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "hereditary prostate carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, familial",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, hereditary",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer, hereditary, 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "HPC7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer, hereditary, 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer aggressiveness",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, 1",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene."
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "RNASEL familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "familial prostate cancer caused by mutation in RNASEL",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "HPC1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "Prca1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "prostate cancer, hereditary, 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "HPC11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "prostate cancer, hereditary, 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "prostate cancer, hereditary, 14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "HPC14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "prostate cancer, hereditary, 14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "prostate cancer, hereditary, 15",
                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "HPC15",
                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "prostate cancer, hereditary, 15",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "prostate cancer, hereditary, X-linked 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "HPCX1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
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            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-2682334",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2682334",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-3928662",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928662",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-3928664",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928664",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-3928665",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928665",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "10596",
            "url": "https://www.rhea-db.org/rhea/10596",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "Q8CA63",
            "url": "https://www.uniprot.org/uniprot/Q8CA63",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CA63-1",
            "url": "https://www.uniprot.org/uniprot/Q8CA63-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CBF3",
            "url": "https://www.uniprot.org/uniprot/Q8CBF3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CBF3-1",
            "url": "https://www.uniprot.org/uniprot/Q8CBF3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8CBF3-2",
            "url": "https://www.uniprot.org/uniprot/Q8CBF3-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MALDCLLLFLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAAYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA",
        "length": 984,
        "header": "sp|Q8CBF3-1|EPHB1_MOUSE Isoform 1 of Ephrin type-B receptor 1  OS=Mus musculus OX=10090 GN=Ephb1 PE=1 SV=1 CANONICAL=Q8CBF3-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q8CA63-1",
            "url": "",
            "sequence": {
                "sequence": "MALDCLLLFLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAGESGGFDVYICLCGWLFIYLYVGS",
                "length": 456,
                "header": "tr|Q8CA63-1|EPHB1_MOUSE Computationally mapped isoform of Ephrin type-B receptor 1  OS=Mus musculus OX=10090 GN=Ephb1 PE=1 SV=1 CANONICAL=Q8CBF3-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 102231538,
                "end_pos": 101918140,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000149800.3",
                        "url": "https://www.ensembl.org/id/ENSMUST00000149800.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000139470.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000139470.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8CBF3-1",
            "url": "",
            "sequence": {
                "sequence": "MALDCLLLFLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAAYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA",
                "length": 984,
                "header": "sp|Q8CBF3-1|EPHB1_MOUSE Isoform 1 of Ephrin type-B receptor 1  OS=Mus musculus OX=10090 GN=Ephb1 PE=1 SV=1 CANONICAL=Q8CBF3-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 102231538,
                "end_pos": 101800688,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000035129",
                        "url": "https://www.ensembl.org/id/ENSMUST00000035129"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000035129",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000035129"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8CBF3-2",
            "url": "",
            "sequence": {
                "sequence": "MALDCLLLFLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAAYSDKLQHYSTGRGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA",
                "length": 943,
                "header": "sp|Q8CBF3-2|EPHB1_MOUSE Isoform 2 of Ephrin type-B receptor 1  OS=Mus musculus OX=10090 GN=Ephb1 PE=1 SV=1 CANONICAL=Q8CBF3-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 102231538,
                "end_pos": 101800688,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000085169",
                        "url": "https://www.ensembl.org/id/ENSMUST00000085169"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000082261",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000082261"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 334,
            "start_aa": "Asn",
            "end_pos": 334,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn334",
            "evidence": [
                {
                    "id": "Q8CBF3",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 426,
            "start_aa": "Asn",
            "end_pos": 426,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn426",
            "evidence": [
                {
                    "id": "Q8CBF3",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 480,
            "start_aa": "Asn",
            "end_pos": 480,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn480",
            "evidence": [
                {
                    "id": "Q8CBF3",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 600,
            "end_pos": 600,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q8CBF3",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CBF3"
                },
                {
                    "database": "PubMed",
                    "id": "32238105",
                    "url": "https://glygen.org/publication/PubMed/32238105"
                }
            ],
            "site_lbl": "Tyr600"
        },
        {
            "start_pos": 928,
            "end_pos": 928,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "site_lbl": "Tyr928"
        }
    ],
    "glycation": [],
    "keywords": [
        "enzyme",
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "EphB1 associates with Grb7 and regulates cell migration.",
            "journal": "J. Biol. Chem.",
            "date": "2002",
            "authors": "Han DC, Shen TL, Miao H, Wang B, Guan JL",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12223469",
                    "url": "https://glygen.org/publication/PubMed/12223469"
                }
            ]
        },
        {
            "title": "EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis.",
            "journal": "J. Cell Biol.",
            "date": "2003",
            "authors": "Vindis C, Cerretti DP, Daniel TO, Huynh-Do U",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12925710",
                    "url": "https://glygen.org/publication/PubMed/12925710"
                }
            ]
        },
        {
            "title": "Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm.",
            "journal": "Neuron",
            "date": "2003",
            "authors": "Williams SE, Mann F, Erskine L, Sakurai T, Wei S, Rossi DJ, Gale NW, Holt CE, Mason CA, Henkemeyer M",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12971893",
                    "url": "https://glygen.org/publication/PubMed/12971893"
                }
            ]
        },
        {
            "title": "Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus.",
            "journal": "J. Cell Biol.",
            "date": "2003",
            "authors": "Ngo M., Henkemeyer M., Ethell I.M., Hickmott P.W., Itkis O.S.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "14691139",
                    "url": "https://glygen.org/publication/PubMed/14691139"
                }
            ]
        },
        {
            "title": "Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway.",
            "journal": "Traffic",
            "date": "2008",
            "authors": "Fasen K, Cerretti DP, Huynh-Do U",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18034775",
                    "url": "https://glygen.org/publication/PubMed/18034775"
                }
            ]
        },
        {
            "title": "EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesis.",
            "journal": "J. Neurosci.",
            "date": "2007",
            "authors": "Henkemeyer M., Chumley M.J., Catchpole T., Kernie S.G., Silvany R.E.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18057206",
                    "url": "https://glygen.org/publication/PubMed/18057206"
                }
            ]
        },
        {
            "title": "Zic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1.",
            "journal": "J. Neurosci.",
            "date": "2008",
            "authors": "Lee R., Mason C.A., Petros T.J.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18524895",
                    "url": "https://glygen.org/publication/PubMed/18524895"
                }
            ]
        },
        {
            "title": "Targeted mutation of EphB1 receptor prevents development of neuropathic hyperalgesia and physical dependence on morphine in mice.",
            "journal": "Mol. Pain",
            "date": "2008",
            "authors": "Han Y., Liu W.T., Song X.J., Henkemeyer M., Song X.S.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19025592",
                    "url": "https://glygen.org/publication/PubMed/19025592"
                }
            ]
        },
        {
            "title": "Gene expression profiling of muscle stem cells identifies novel regulators of postnatal myogenesis.",
            "journal": "Front. Cell Dev. Biol.",
            "date": "2016",
            "authors": "Alonso-Martin S, Rochat A, Mademtzoglou D, Morais J, de Reynies A, Aurade F, Chang TH, Zammit PS, Relaix F",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27446912",
                    "url": "https://glygen.org/publication/PubMed/27446912"
                }
            ]
        },
        {
            "title": "EphB1 interaction with caveolin-1 in endothelial cells modulates caveolae biogenesis.",
            "journal": "Molecular biology of the cell",
            "date": "2020-05-15",
            "authors": "Tiruppathi Chinnaswamy, Regmi Sushil C, Wang Dong-Mei, Mo Gary C H, Toth Peter T, Vogel Stephen M, Stan Radu V, Henkemeyer Mark, Minshall Richard D, Rehman Jalees, Malik Asrar B",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "Q8CBF3",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "32238105",
                    "url": "https://glygen.org/publication/PubMed/32238105"
                }
            ]
        },
        {
            "title": "Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase.",
            "journal": "J. Biol. Chem.",
            "date": "1998",
            "authors": "Stein E, Huynh-Do U, Lane AA, Cerretti DP, Daniel TO",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "9430661",
                    "url": "https://glygen.org/publication/PubMed/9430661"
                }
            ]
        },
        {
            "title": "PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands.",
            "journal": "Neuron",
            "date": "1998",
            "authors": "Torres R, Firestein BL, Dong H, Staudinger J, Olson EN, Huganir RL, Bredt DS, Gale NW, Yancopoulos GD",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "9883737",
                    "url": "https://glygen.org/publication/PubMed/9883737"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:270190",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:270190",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-2682334",
            "name": "EPH-Ephrin signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2682334",
            "resource": "Reactome",
            "description": "EPH-Ephrin signaling"
        },
        {
            "id": "R-MMU-3928662",
            "name": "EPHB-mediated forward signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928662",
            "resource": "Reactome",
            "description": "EPHB-mediated forward signaling"
        },
        {
            "id": "R-MMU-3928664",
            "name": "Ephrin signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928664",
            "resource": "Reactome",
            "description": "Ephrin signaling"
        },
        {
            "id": "R-MMU-3928665",
            "name": "EPH-ephrin mediated repulsion of cells",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928665",
            "resource": "Reactome",
            "description": "EPH-ephrin mediated repulsion of cells"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P09759-1",
            "protein_name": "Ephrin type-B receptor 1",
            "gene_name": "Ephb1",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MALDCLLLFLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKAGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA",
                "length": 984
            },
            "evidence": [
                {
                    "id": "Q8CBF3",
                    "url": "https://omabrowser.org/oma/group/Q8CBF3/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "P54762-1",
            "protein_name": "Ephrin type-B receptor 1",
            "gene_name": "EPHB1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRVQISQSPTAMA",
                "length": 984
            },
            "evidence": [
                {
                    "id": "Q8CBF3",
                    "url": "https://omabrowser.org/oma/group/Q8CBF3/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 6,
                "go_terms": [
                    {
                        "name": "ATP binding",
                        "id": "GO:0005524",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ephrin receptor activity",
                        "id": "GO:0005003",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005003",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein tyrosine kinase activity",
                        "id": "GO:0004713",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein-containing complex binding",
                        "id": "GO:0044877",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "transmembrane-ephrin receptor activity",
                        "id": "GO:0005005",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005005",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "axon guidance receptor activity",
                        "id": "GO:0008046",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008046",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 27,
                "go_terms": [
                    {
                        "name": "protein phosphorylation",
                        "id": "GO:0006468",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cranial nerve development",
                        "id": "GO:0021545",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021545",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "hindbrain tangential cell migration",
                        "id": "GO:0021934",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021934",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "angiogenesis",
                        "id": "GO:0001525",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ephrin receptor signaling pathway",
                        "id": "GO:0048013",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "detection of temperature stimulus involved in sensory perception of pain",
                        "id": "GO:0050965",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050965",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein autophosphorylation",
                        "id": "GO:0046777",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dendritic spine development",
                        "id": "GO:0060996",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060996",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of synapse assembly",
                        "id": "GO:0051965",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell chemotaxis",
                        "id": "GO:0060326",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "optic nerve morphogenesis",
                        "id": "GO:0021631",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021631",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "central nervous system projection neuron axonogenesis",
                        "id": "GO:0021952",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021952",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "modulation of chemical synaptic transmission",
                        "id": "GO:0050804",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "camera-type eye morphogenesis",
                        "id": "GO:0048593",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048593",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dendritic spine morphogenesis",
                        "id": "GO:0060997",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060997",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of ERK1 and ERK2 cascade",
                        "id": "GO:0070372",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070372",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "axon guidance",
                        "id": "GO:0007411",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell-substrate adhesion",
                        "id": "GO:0031589",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031589",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "establishment of cell polarity",
                        "id": "GO:0030010",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neurogenesis",
                        "id": "GO:0022008",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of JNK cascade",
                        "id": "GO:0046328",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046328",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neural precursor cell proliferation",
                        "id": "GO:0061351",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061351",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "retinal ganglion cell axon guidance",
                        "id": "GO:0031290",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031290",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "immunological synapse formation",
                        "id": "GO:0001771",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001771",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "skeletal muscle satellite cell activation",
                        "id": "GO:0014719",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014719",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of skeletal muscle satellite cell proliferation",
                        "id": "GO:1902723",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902723",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of satellite cell differentiation",
                        "id": "GO:1902725",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902725",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 11,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glutamatergic synapse",
                        "id": "GO:0098978",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endoplasmic reticulum",
                        "id": "GO:0005783",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "axon",
                        "id": "GO:0030424",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dendrite",
                        "id": "GO:0030425",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane raft",
                        "id": "GO:0045121",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "early endosome membrane",
                        "id": "GO:0031901",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "filopodium tip",
                        "id": "GO:0032433",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032433",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8CBF3",
                                "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 334,
            "end_pos": 336,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 426,
            "end_pos": 428,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 480,
            "end_pos": 482,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 977,
            "end_pos": 979,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "Phosphorylated. Autophosphorylation is stimulated by the ligand EFNB1. Required for interaction with SH2 domain-containing interactors, for activation of the MAPK/ERK and JUN signaling cascades and for ubiquitination by CBL (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                },
                {
                    "database": "PubMed",
                    "id": "P54762",
                    "url": "https://glygen.org/publication/PubMed/P54762"
                }
            ]
        },
        {
            "annotation": "Ubiquitinated; (EFNB1)ligand-induced poly- and/or multi-ubiquitination by CBL is regulated by SRC and leads to lysosomal degradation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8CBF3",
                    "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                },
                {
                    "database": "PubMed",
                    "id": "18034775",
                    "url": "https://glygen.org/publication/PubMed/18034775"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [
        {
            "id": "10596",
            "name": "",
            "equation": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q63132-1",
                "Q9WUD9-1",
                "P57760-1",
                "P35739-1",
                "F1LYY7-1",
                "A0A8I6GCV6-1",
                "Q63117-1",
                "Q5U2X5-1",
                "Q63474-1",
                "O08680-1",
                "O35346-1",
                "P54757-1",
                "P54758-1",
                "P54759-1",
                "P70600-1",
                "Q00495-1",
                "Q03351-1",
                "Q04589-1",
                "P06494-1",
                "P09759-1",
                "P29321-1",
                "P32577-1",
                "Q6XUX2-1",
                "Q4V8A3-1",
                "Q62662-1",
                "Q62799-1",
                "Q62844-1",
                "Q62956-1",
                "Q63184-1",
                "Q63470-1",
                "Q498D6-1",
                "Q01621-1",
                "Q6P6U0-1",
                "Q63604-1",
                "P09760-1",
                "Q01986-1",
                "Q62862-1",
                "Q63572-1",
                "Q07014-1",
                "Q4KSH7-1",
                "G3V9H8-1",
                "P15127-1",
                "O08775-1",
                "P53767-1",
                "Q05030-1",
                "P55146-1",
                "Q64725-1",
                "Q63802-1",
                "Q64716-1",
                "P09215-1",
                "Q62689-1",
                "F1LM93-1",
                "P36506-1",
                "P20786-1",
                "P24062-1",
                "Q924U5-1",
                "Q63272-1",
                "B2RYC7-1",
                "P41243-1",
                "M0RDA4-1",
                "Q62838-1",
                "Q63116-1",
                "A0A8I6AM23-1",
                "P50545-1",
                "P57097-1",
                "P97523-1",
                "Q91ZT1-1",
                "D4A7W7-1",
                "F1LVI0-1",
                "E9PSY0-1",
                "A0A0G2K6M9-1",
                "F1LSN4-1",
                "F1MAJ0-1",
                "A0A0R4J8U1-1",
                "A0A8I6A5T6-1",
                "D3ZDS3-1",
                "D4ADZ5-1",
                "F1LSG7-1",
                "F1LRZ0-1",
                "D3ZBN3-1",
                "F1M0N1-1",
                "G3V6K6-1",
                "D3ZD03-1",
                "D3ZZK3-1",
                "E9PT20-1",
                "D4A584-1",
                "D3ZDH4-1",
                "A0A8I5ZVE3-1",
                "A0A8I6AWX7-1",
                "Q4KM97-1",
                "Q501W1-1",
                "B5DFD6-1",
                "Q5FVG7-1",
                "D3ZCD0-1",
                "A0A8I5ZP97-1",
                "A0A0G2JW59-1",
                "B1WC09-1",
                "Q01134-1",
                "P11980-1",
                "G3V783-1",
                "Q9UM73-1",
                "O15146-1",
                "P42679-1",
                "P08922-1",
                "P07947-1",
                "Q12866-1",
                "P00519-1",
                "Q07912-1",
                "P42684-1",
                "Q9UF33-1",
                "P10721-1",
                "P08069-1",
                "P06239-1",
                "P51451-1",
                "Q06187-1",
                "P51813-1",
                "Q9UIG0-1",
                "P49760-1",
                "P49761-4",
                "Q9HAZ1-1",
                "P49759-1",
                "P07333-1",
                "Q5JZY3-1",
                "Q6XUX3-1",
                "P00533-1",
                "Q9Y463-1",
                "P29317-1",
                "Q9NR20-1",
                "Q13627-1",
                "P54760-1",
                "P41240-1",
                "Q16832-1",
                "Q15375-1",
                "P29323-1",
                "P22455-1",
                "P16591-1",
                "P29322-1",
                "P54756-1",
                "P29320-1",
                "Q08345-1",
                "Q92630-1",
                "Q05397-1",
                "P54753-1",
                "Q15303-1",
                "P36888-1",
                "P04626-1",
                "P21860-1",
                "Q14289-1",
                "O43781-1",
                "P54764-1",
                "P19525-1",
                "P21709-1",
                "P54762-1",
                "P22607-1",
                "P21802-1",
                "P52333-1",
                "P11362-1",
                "P42685-1",
                "P06213-1",
                "P14616-1",
                "Q05655-1",
                "Q08881-1",
                "P07332-1",
                "P08631-1",
                "P29376-1",
                "O60674-1",
                "P23458-1",
                "P09769-1",
                "P43405-1",
                "P06241-1",
                "P07948-1",
                "P46734-1",
                "P45985-1",
                "Q02750-1",
                "P52564-1",
                "O14733-1",
                "Q13163-1",
                "Q16288-1",
                "P36507-1",
                "Q16620-1",
                "P08581-1",
                "P04629-1",
                "Q14680-1",
                "Q01974-1",
                "P09619-1",
                "P07949-1",
                "Q504Y2-1",
                "P34925-1",
                "P16234-1",
                "Q13882-1",
                "Q04912-1",
                "O43353-1",
                "Q06418-1",
                "P30530-1",
                "Q96KB5-1",
                "Q15569-1",
                "Q96S53-1",
                "Q6J9G0-1",
                "P42680-1",
                "P35916-2",
                "P0C1S8-1",
                "P17948-1",
                "P29597-1",
                "P42681-1",
                "P35590-1",
                "Q13470-1",
                "P33981-1",
                "P30291-1",
                "P12931-1",
                "P35968-1",
                "P43403-1",
                "O75716-1",
                "Q02763-1",
                "Q9H3Y6-1",
                "P35790-1",
                "P14618-1",
                "P24604-1",
                "O54967-1",
                "P00520-1",
                "Q9Z188-1",
                "P35969-1",
                "P52332-1",
                "P08923-1",
                "Q00342-1",
                "Q62120-1",
                "Q4JIM5-1",
                "P97504-1",
                "P42682-1",
                "Q60629-1",
                "P97793-1",
                "P16277-1",
                "O35491-1",
                "O35492-1",
                "O35493-1",
                "Q9Z277-1",
                "P35991-1",
                "P22518-1",
                "Q8BYG9-1",
                "P54754-1",
                "P54761-1",
                "Q6XUX1-1",
                "Q62371-1",
                "Q60750-1",
                "Q61527-1",
                "Q62413-1",
                "Q61214-1",
                "Q61772-1",
                "Q61851-1",
                "Q922Y0-1",
                "Q922K9-1",
                "O09127-1",
                "P16092-1",
                "Q03142-1",
                "P29319-1",
                "Q01279-1",
                "P70424-1",
                "P21803-1",
                "Q8CBF3-1",
                "P41241-1",
                "Q03963-1",
                "Q8BI55-1",
                "P54763-3",
                "P16879-1",
                "P09581-1",
                "P34152-3",
                "P14234-1",
                "P39688-1",
                "Q03146-1",
                "Q03145-1",
                "Q61526-1",
                "P70451-1",
                "Q5U4C9-1",
                "Q9QVP9-1",
                "Q03137-1",
                "Q60751-1",
                "Q62137-1",
                "P28867-1",
                "P25911-1",
                "P48025-1",
                "Q9WTL4-1",
                "P41242-1",
                "P05532-1",
                "P06240-1",
                "P08103-1",
                "P15208-1",
                "Q03526-1",
                "Q9WVS7-1",
                "P70236-1",
                "P31938-1",
                "P47809-1",
                "Q61846-1",
                "Q60805-1",
                "Q63932-1",
                "O09110-1",
                "P26618-1",
                "Q8CE90-1",
                "P16056-1",
                "P05622-1",
                "P15209-1",
                "Q6VNS1-1",
                "Q61006-1",
                "Q3UFB7-1",
                "Q5RJI4-1",
                "Q9JJ78-1",
                "P58801-1",
                "P55144-1",
                "Q8VCT9-1",
                "O70146-1",
                "Q62190-1",
                "Q62270-1",
                "P35546-1",
                "P35761-1",
                "Q9Z138-1",
                "Q9R117-1",
                "O88697-1",
                "P05480-2",
                "Q01887-1",
                "Q02858-1",
                "Q06806-1",
                "Q00993-1",
                "Q64434-1",
                "Q78DX7-1",
                "Q6J9G1-1",
                "Q99ML2-1",
                "P43404-1",
                "P35917-1",
                "P47810-1",
                "P35918-1",
                "Q04736-1",
                "Q66JT0-1",
                "O54804-1",
                "P52480-1",
                "P14680-1",
                "P21965-1",
                "P22216-1",
                "P32490-1",
                "P06784-1",
                "P08018-1",
                "P32350-1",
                "P32491-1",
                "P54199-1",
                "Q54G28-1",
                "Q54N73-1",
                "Q54R58-1",
                "P18160-1",
                "P18161-1",
                "Q54BC9-1",
                "Q54I36-1",
                "Q54QV3-1",
                "Q552C6-1",
                "Q55CL6-1",
                "Q75JK0-1",
                "Q76NV1-1",
                "Q23977-1",
                "P18475-1",
                "P09208-1",
                "P13368-1",
                "Q24145-1",
                "Q24488-1",
                "Q27324-1",
                "P08630-1",
                "P00522-1",
                "P00528-1",
                "P04412-1",
                "Q9V422-1",
                "Q9V6K3-1",
                "Q9V9J3-1",
                "Q9VBW3-1",
                "P49762-1",
                "P83102-1",
                "Q24324-1",
                "Q9VPC0-1",
                "P49657-1",
                "P54350-1",
                "P18106-4",
                "Q07407-1",
                "Q09147-1",
                "Q24592-1",
                "Q9I7F7-1",
                "Q9V3D5-1",
                "Q9VZI2-1",
                "Q9V4E5-1",
                "Q8INJ8-1",
                "Q7KJ08-1",
                "Q9VJ04-1"
            ],
            "evidence": [
                {
                    "id": "10596",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/10596"
                }
            ]
        },
        {
            "id": "R-MMU-3928578",
            "name": "EPH receptors autophosphorylate",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q61772-1",
                "Q03145-1",
                "P29319-1",
                "Q03137-1",
                "O09127-1",
                "Q8CBF3-1",
                "P54763-3",
                "Q60750-1",
                "Q62413-1",
                "Q8BYG9-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928578",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928578"
                }
            ]
        },
        {
            "id": "R-MMU-3928591",
            "name": "EPH:EFN tetramers oligomerise",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q61772-1",
                "Q03145-1",
                "P29319-1",
                "Q03137-1",
                "O09127-1",
                "Q8CBF3-1",
                "P54763-3",
                "Q60750-1",
                "Q62413-1",
                "Q8BYG9-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928591",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928591"
                }
            ]
        },
        {
            "id": "R-MMU-3928592",
            "name": "p190RhoGEF exchanges GTP for GDP on RHOA, activating it",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q9QUI0-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928592",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928592"
                }
            ]
        },
        {
            "id": "R-MMU-3928595",
            "name": "N-WASP binds ARP2/3 and G-actin",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P60710-1",
                "P60766-2",
                "Q8CBF3-1",
                "P54763-3",
                "P63260-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928595",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928595"
                }
            ]
        },
        {
            "id": "R-MMU-3928597",
            "name": "EPH:EFN dimers tetramerise",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q61772-1",
                "Q03145-1",
                "P29319-1",
                "Q03137-1",
                "O09127-1",
                "Q8CBF3-1",
                "P54763-3",
                "Q60750-1",
                "Q62413-1",
                "Q8BYG9-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928597",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928597"
                }
            ]
        },
        {
            "id": "R-MMU-3928598",
            "name": "Recruitment of p190RhoGEF to p-FAK",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928598",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928598"
                }
            ]
        },
        {
            "id": "R-MMU-3928601",
            "name": "CDC42 and PIP2 bind WASL, activating it",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P60766-2",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928601",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928601"
                }
            ]
        },
        {
            "id": "R-MMU-3928604",
            "name": "SFKs phosphorylate VAV2,3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q61772-1",
                "Q03145-1",
                "P29319-1",
                "Q03137-1",
                "P05480-2",
                "Q04736-1",
                "P39688-1",
                "P25911-1",
                "O09127-1",
                "Q8CBF3-1",
                "P54763-3",
                "Q60750-1",
                "Q62413-1",
                "Q8BYG9-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928604",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928604"
                }
            ]
        },
        {
            "id": "R-MMU-3928607",
            "name": "p-EPHs bind VAV2,3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q61772-1",
                "Q03145-1",
                "P29319-1",
                "Q03137-1",
                "P05480-2",
                "Q04736-1",
                "P39688-1",
                "P25911-1",
                "O09127-1",
                "Q8CBF3-1",
                "P54763-3",
                "Q60750-1",
                "Q62413-1",
                "Q8BYG9-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928607",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928607"
                }
            ]
        },
        {
            "id": "R-MMU-3928612",
            "name": "KALRN exchanges GTP for GDP on RAC1, activating it",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [
                "R-ALL-29438"
            ],
            "output_participant_list": [
                "R-ALL-114549"
            ],
            "enzyme_list": [
                "A2CG49-1",
                "P54754-1",
                "P54761-1",
                "P63001-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928612",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928612"
                }
            ]
        },
        {
            "id": "R-MMU-3928614",
            "name": "EFNB:GRB4 binds GIT1",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "P39688-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928614",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928614"
                }
            ]
        },
        {
            "id": "R-MMU-3928615",
            "name": "EFNBs bind SFKs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "P39688-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928615",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928615"
                }
            ]
        },
        {
            "id": "R-MMU-3928617",
            "name": "EPHB2 binds KALRN",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "A2CG49-1",
                "P54754-1",
                "P54761-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928617",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928617"
                }
            ]
        },
        {
            "id": "R-MMU-3928624",
            "name": "EPHBs bind EFNBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928624",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928624"
                }
            ]
        },
        {
            "id": "R-MMU-3928625",
            "name": "PAKs autophosphorylate",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "P39688-1",
                "Q61036-1",
                "Q8CIN4-1",
                "O88643-1",
                "P63001-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928625",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928625"
                }
            ]
        },
        {
            "id": "R-MMU-3928627",
            "name": "EPHB phosphorylates TIAM1",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "Q04736-1",
                "P39688-1",
                "P25911-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928627",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928627"
                }
            ]
        },
        {
            "id": "R-MMU-3928628",
            "name": "VAV exchanges GTP for GDP on RAC1, activating it",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q61772-1",
                "Q03145-1",
                "P29319-1",
                "Q03137-1",
                "P05480-2",
                "Q04736-1",
                "P39688-1",
                "P25911-1",
                "P63001-1",
                "O09127-1",
                "Q8CBF3-1",
                "P54763-3",
                "Q60750-1",
                "Q62413-1",
                "Q8BYG9-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928628",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928628"
                }
            ]
        },
        {
            "id": "R-MMU-3928631",
            "name": "GIT1 binds bPIX",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "P39688-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928631",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928631"
                }
            ]
        },
        {
            "id": "R-MMU-3928633",
            "name": "bPIX exchanges GTP for GDP on RAC, activating it",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "P39688-1",
                "P63001-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928633",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928633"
                }
            ]
        },
        {
            "id": "R-MMU-3928639",
            "name": "p-EFNB binds GRB4",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "P39688-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928639",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928639"
                }
            ]
        },
        {
            "id": "R-MMU-3928641",
            "name": "PAK binds RAC and bPIX",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "P39688-1",
                "Q61036-1",
                "Q8CIN4-1",
                "O88643-1",
                "P63001-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928641",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928641"
                }
            ]
        },
        {
            "id": "R-MMU-3928645",
            "name": "EPHB:NMDAR binds TIAM1",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "Q04736-1",
                "P39688-1",
                "P25911-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928645",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928645"
                }
            ]
        },
        {
            "id": "R-MMU-3928656",
            "name": "gamma-secretase cleaves EPHB2",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P49769-1",
                "Q8CBF3-1",
                "Q61144-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928656",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928656"
                }
            ]
        },
        {
            "id": "R-MMU-3928657",
            "name": "MMP2,9 cleave EPHB",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P33434-1",
                "P41245-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-3928657",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3928657"
                }
            ]
        },
        {
            "id": "R-MMU-4093329",
            "name": "EFNBs bind SDCBP",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-4093329",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-4093329"
                }
            ]
        },
        {
            "id": "R-MMU-4093331",
            "name": "Ras:GTP binds p120-RasGAP",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q8CBF3-1",
                "Q61411-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-4093331",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-4093331"
                }
            ]
        },
        {
            "id": "R-MMU-4093332",
            "name": "p-EPHB phosphorylates SDC2",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [
                "R-MMU-2090052"
            ],
            "output_participant_list": [
                "R-MMU-4093306"
            ],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-4093332",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-4093332"
                }
            ]
        },
        {
            "id": "R-MMU-4093336",
            "name": "p-TIAM1 exchanges GTP for GDP on RAC1, activating it",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "P05480-2",
                "Q04736-1",
                "P39688-1",
                "P25911-1",
                "P63001-1",
                "Q8CBF3-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-4093336",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-4093336"
                }
            ]
        },
        {
            "id": "R-MMU-4093339",
            "name": "p120-RasGAP activates GTP hydrolysis on RAS, inactivating it",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P54754-1",
                "P54761-1",
                "Q8CBF3-1",
                "Q61411-1",
                "P54763-3"
            ],
            "evidence": [
                {
                    "id": "R-MMU-4093339",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-4093339"
                }
            ]
        }
    ],
    "reaction_participants": [
        {
            "participant_id": "R-ALL-114549",
            "participant_name": "GDP [plasma membrane]",
            "crossref": [
                {
                    "id": "C00035",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "17552",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "2410",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "HMDB0001201",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "000008215481",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "8145509",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "C00035",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "17552",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "2410",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "HMDB0001201",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "000008215481",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "8145509",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "C00035",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "HMDB0001201",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "8145509",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "17552",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "2410",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "000008215481",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "C00035",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "17552",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "2410",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "HMDB0001201",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "000008215481",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "8145509",
                    "database": "PubChem Substance",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-ALL-29438",
            "participant_name": "GTP [cytosol]",
            "crossref": [
                {
                    "id": "000060094177",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "37565",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C00044",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "C00044",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "000060094177",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "37565",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C00044",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "37565",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "000060094177",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "C00044",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "000060094177",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "37565",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C00044",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "37565",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "000060094177",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "C00044",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "000060094177",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "37565",
                    "database": "ChEBI",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-MMU-2090052",
            "participant_name": "Sdc2 [plasma membrane]",
            "crossref": [
                {
                    "id": "ENSMUST00000022871",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "ENSMUSG00000022261",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "1349165",
                    "database": "MGI",
                    "url": ""
                },
                {
                    "id": "P43407",
                    "database": "PRO",
                    "url": ""
                },
                {
                    "id": "NP_032330.1",
                    "database": "RefSeq",
                    "url": ""
                },
                {
                    "id": "P43407",
                    "database": "UniProt",
                    "url": ""
                },
                {
                    "id": "ENSMUSP00000022871",
                    "database": "Ensembl",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-MMU-4093306",
            "participant_name": "phospho-Sdc2 [plasma membrane]",
            "crossref": [
                {
                    "id": "P43407",
                    "database": "UniProt",
                    "url": ""
                },
                {
                    "id": "ENSMUSG00000022261",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "NP_032330.1",
                    "database": "RefSeq",
                    "url": ""
                },
                {
                    "id": "1349165",
                    "database": "MGI",
                    "url": ""
                },
                {
                    "id": "ENSMUSP00000022871",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "ENSMUST00000022871",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "P43407",
                    "database": "PRO",
                    "url": ""
                }
            ]
        }
    ],
    "reaction_enzymes": [
        {
            "uniprot_ac": "A0A0G2JW59",
            "gene_name": "Flt3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0G2JW59",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JW59"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2JW59",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JW59"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A0G2K6M9",
            "gene_name": "Btk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0G2K6M9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K6M9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2K6M9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K6M9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A0R4J8U1",
            "gene_name": "Zap70",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0R4J8U1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0R4J8U1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0R4J8U1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0R4J8U1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I5ZP97",
            "gene_name": "Dyrk1b",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I5ZP97",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I5ZP97",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I5ZVE3",
            "gene_name": "Ephb3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I5ZVE3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZVE3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I5ZVE3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZVE3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6A5T6",
            "gene_name": "Mst1r",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6A5T6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6A5T6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6A5T6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6A5T6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6AM23",
            "gene_name": "Jak1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6AM23",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AM23"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6AM23",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AM23"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6AWX7",
            "gene_name": "Dyrk4",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6AWX7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6AWX7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6GCV6",
            "gene_name": "Ltk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6GCV6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6GCV6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6GCV6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6GCV6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A2CG49",
            "gene_name": "Kalrn",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "A2CG49",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A2CG49"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A2CG49",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A2CG49"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B1WC09",
            "gene_name": "Ddr2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "B1WC09",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B1WC09"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B1WC09",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B1WC09"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B2RYC7",
            "gene_name": "Tec",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "B2RYC7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RYC7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B2RYC7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RYC7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B5DFD6",
            "gene_name": "Tie1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "B5DFD6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B5DFD6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B5DFD6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B5DFD6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZBN3",
            "gene_name": "Epha2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZBN3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZBN3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZBN3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZBN3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZCD0",
            "gene_name": "Tek",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZCD0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZCD0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZCD0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZCD0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZD03",
            "gene_name": "Tyk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZD03",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZD03"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZD03",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZD03"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZDH4",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZDH4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDH4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZDH4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDH4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZDS3",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZDS3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDS3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZDS3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDS3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZZK3",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZZK3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZZK3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZZK3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZZK3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4A584",
            "gene_name": "Fes",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D4A584",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A584"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D4A584",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A584"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4A7W7",
            "gene_name": "Itk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D4A7W7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A7W7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D4A7W7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A7W7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4ADZ5",
            "gene_name": "Wee2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D4ADZ5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ADZ5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D4ADZ5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ADZ5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "E9PSY0",
            "gene_name": "Axl",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "E9PSY0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PSY0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "E9PSY0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PSY0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "E9PT20",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "E9PT20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PT20"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "E9PT20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PT20"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LM93",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LM93",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LM93"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LM93",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LM93"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LRZ0",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LRZ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LRZ0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LRZ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LRZ0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LSG7",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LSG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSG7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "F1LSG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSG7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LSN4",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LSN4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSN4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LSN4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSN4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LVI0",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LVI0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LVI0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LVI0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LVI0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LYY7",
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            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LYY7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LYY7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LYY7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LYY7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1M0N1",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1M0N1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1M0N1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1M0N1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1M0N1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1MAJ0",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1MAJ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1MAJ0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1MAJ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1MAJ0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V6K6",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V6K6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V6K6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V6K6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V6K6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V783",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V9H8",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V9H8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V9H8"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V9H8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V9H8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "M0RDA4",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "M0RDA4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/M0RDA4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "M0RDA4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/M0RDA4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O08680",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O08680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08680"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O08680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08680"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O08775",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O08775",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08775"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O08775",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08775"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O09110",
            "gene_name": "Map2k3",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O09110",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09110"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O09110",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09110"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O09127",
            "gene_name": "Epha8",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O09127",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09127"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O09127",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09127"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O14733",
            "gene_name": "MAP2K7",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O14733",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O14733"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O14733",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O14733"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O15146",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O15146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O15146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O15146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O15146"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35346",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O35346",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35346"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35346",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35346"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35491",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O35491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35491"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35491"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35492",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O35492",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35492"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35492",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35492"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35493",
            "gene_name": "Clk4",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O35493",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35493"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35493",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35493"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O43353",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O43353",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43353"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O43353",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43353"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O43353",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43353"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O43781",
            "gene_name": "DYRK3",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O43781",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43781"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O43781",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43781"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O54804",
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                {
                    "ec_number": "2.7.1.32",
                    "activity": "ATP + choline = ADP + H(+) + phosphocholine.",
                    "evidence": [
                        {
                            "id": "O54804",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54804"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.82",
                    "activity": "ATP + ethanolamine = ADP + H(+) + phosphoethanolamine.",
                    "evidence": [
                        {
                            "id": "O54804",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54804"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.32",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O54804",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54804"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O54967",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O54967",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54967"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O54967",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54967"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O54967",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54967"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
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                        {
                            "id": "O54967",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54967"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "O60674",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O60674",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O60674"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "O60674",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O60674"
                        }
                    ]
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            ]
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        {
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O70146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O70146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
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                        {
                            "id": "O70146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O70146"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O75716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O75716"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O75716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O75716"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
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                        {
                            "id": "O75716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O75716"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "O88643",
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                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O88643",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O88643"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O88643",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O88643"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "O88697",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O88697",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O88697"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O88697",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O88697"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
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                        {
                            "id": "O88697",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O88697"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P00519",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P00519",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00519"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P00519",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00519"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P00520",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P00520",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00520"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P00520",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00520"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P00522",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P00522",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00522"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P00522",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00522"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P00528",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P00528",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00528"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P00528",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00528"
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                    ]
                }
            ]
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        {
            "uniprot_ac": "P00533",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P00533",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00533"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P00533",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00533"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P04412",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P04412",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04412"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P04412",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04412"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P04626",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P04626",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04626"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P04626",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04626"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P04629",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P04629",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04629"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P04629",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04629"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P05480",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P05480",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05480"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P05480",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05480"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P05532",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P05532",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05532"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P05532",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05532"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P05622",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P05622",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05622"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P05622",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05622"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P06213",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P06213",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P06213"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P06213",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P06213"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P06239",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
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                    "ec_number": "2.7.10.2",
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                            "url": "https://www.uniprot.org/uniprot/P06240"
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                    "ec_number": "2.7.10.2",
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                {
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                            "url": "https://www.uniprot.org/uniprot/P06241"
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                    "ec_number": "2.7.10.1",
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                            "database": "UniProtKB",
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                            "url": "https://www.uniprot.org/uniprot/P06494"
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P06784",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P06784"
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                    ]
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
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                            "id": "P06784",
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                            "url": "https://www.uniprot.org/uniprot/P06784"
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P07332"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "url": "https://www.uniprot.org/uniprot/P07332"
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P07333",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P07333"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P07333",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P07333"
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P07947",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P07947"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "database": "UniProtKB",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P07948",
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                            "url": "https://www.uniprot.org/uniprot/P07948"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P07948",
                            "database": "UniProtKB",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P07949",
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                            "url": "https://www.uniprot.org/uniprot/P07949"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P07949",
                            "database": "UniProtKB",
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                    "ec_number": "2.7.12.2",
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                {
                    "ec_number": "2.7.12.2",
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                            "database": "UniProtKB",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08069",
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                    ]
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                {
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                            "id": "P08069",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08103",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08103"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P08103",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08103"
                        }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08581",
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                            "url": "https://www.uniprot.org/uniprot/P08581"
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P08581",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08581"
                        }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08630",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P08630",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08630"
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08631",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08631"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P08631",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08631"
                        }
                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08922",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08922"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P08922",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08922"
                        }
                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08923",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08923"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08923",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08923"
                        }
                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P09208",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09208"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P09208",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09208"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.11.13",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P09215",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09215"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
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                        {
                            "id": "P09215",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09215"
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                    "ec_number": "2.7.10.1",
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                            "id": "P09581",
                            "database": "UniProtKB",
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                    ]
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        {
            "uniprot_ac": "P09619",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P09619",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09619"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P09619",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09619"
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09759"
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P09759",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09759"
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                }
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                    "ec_number": "2.7.10.2",
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                            "id": "P09760",
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                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "P09760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09760"
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "P09769",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09769"
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        {
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                    "ec_number": "2.7.10.2",
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                            "id": "P0C1S8",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P0C1S8",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P10721",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P10721"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P10721",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P10721"
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11362"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P11362",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11362"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.1.40",
                    "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.",
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                            "id": "P11980",
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                            "url": "https://www.uniprot.org/uniprot/P11980"
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                    ]
                },
                {
                    "ec_number": "2.7.1.40",
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                            "id": "P11980",
                            "database": "UniProtKB",
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
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                    ]
                }
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                {
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                {
                    "ec_number": "2.7.10.1",
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                {
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                    "ec_number": "2.7.10.2",
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                {
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                            "id": "P18161",
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                            "id": "P18475",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P21860",
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                            "id": "P21965",
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                    "ec_number": "2.7.12.1",
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                            "id": "P21965",
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                    "ec_number": "2.7.12.1",
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                {
                    "ec_number": "2.7.12.1",
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                            "id": "P22216",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22216"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "P22455",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22455"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P22455",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22455"
                        }
                    ]
                }
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        {
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
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                            "id": "P22518",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22518"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
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                        {
                            "id": "P22518",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22518"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "P22607",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22607"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P22607",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22607"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P23458",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P23458"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P23458",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P23458"
                        }
                    ]
                }
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        },
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P24062",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24062"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P24062",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24062"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P24604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24604"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P24604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24604"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P25911",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P25911"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P25911",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P25911"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P26618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P26618"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P26618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P26618"
                        }
                    ]
                }
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        },
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P28867",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P28867"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P28867",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P28867"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "",
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                        {
                            "id": "P28867",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P28867"
                        }
                    ]
                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P29317",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29317"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P29317",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29317"
                        }
                    ]
                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P29319",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29319"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P29319",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29319"
                        }
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                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P29320",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29320"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P29320",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29320"
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                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P29321",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29321"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29321"
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P29322",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29322"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                            "id": "P29322",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29322"
                        }
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                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P29323",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29323"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P29323",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29323"
                        }
                    ]
                }
            ]
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P29376",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29376"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                            "id": "P29376",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29376"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P29597",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29597"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "id": "P29597",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29597"
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                }
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P30291",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P30291"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P30291",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P30291"
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                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P30530",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P30530"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P30530",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P30530"
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                    ]
                }
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P31938",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P31938"
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                    ]
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P31938",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P31938"
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                    ]
                }
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P32350",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32350"
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                    ]
                },
                {
                    "ec_number": "2.7.12.1",
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                            "id": "P32350",
                            "database": "UniProtKB",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P32490",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32490"
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                    ]
                },
                {
                    "ec_number": "2.7.12.2",
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                            "id": "P32490",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32490"
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                }
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        {
            "uniprot_ac": "P32491",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P32491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32491"
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                    ]
                },
                {
                    "ec_number": "2.7.12.2",
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                            "id": "P32491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32491"
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                }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P32577",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32577"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                    "evidence": [
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                            "id": "P32577",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32577"
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                    ]
                }
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        {
            "uniprot_ac": "P33434",
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                {
                    "ec_number": "3.4.24.24",
                    "activity": "Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln.",
                    "evidence": [
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                            "id": "P33434",
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                            "url": "https://www.uniprot.org/uniprot/P33434"
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                    ]
                },
                {
                    "ec_number": "3.4.24.24",
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                            "id": "P33434",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P33434"
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                    ]
                }
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P33981",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P33981"
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                    ]
                },
                {
                    "ec_number": "2.7.12.1",
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                            "id": "P33981",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P33981"
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                    ]
                }
            ]
        },
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P34152",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34152"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "id": "P34152",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34152"
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                    ]
                }
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        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P34925",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34925"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
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                            "id": "P34925",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34925"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P35546",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "P35546",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35546"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35546"
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                    "ec_number": "2.7.10.1",
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                    ]
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                {
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                    "ec_number": "2.7.10.1",
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                            "id": "P35739",
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                            "database": "UniProtKB",
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                    "ec_number": "2.7.12.1",
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                    ]
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                {
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                            "id": "P35790",
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                    ]
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                {
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                            "id": "P35790",
                            "database": "UniProtKB",
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                {
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                {
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                    "ec_number": "2.7.10.2",
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                    ]
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                    "ec_number": "2.7.12.2",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                            "id": "P41243",
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                    "ec_number": "3.4.24.35",
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                            "id": "P41245",
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                            "id": "P41245",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                            "id": "P42679",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                            "id": "P42681",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                    ]
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                    "ec_number": "2.7.10.2",
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                            "id": "P42684",
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                    "ec_number": "2.7.10.2",
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                            "id": "P42685",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42685",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P43403",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P43403",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P43404",
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                    ]
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P43405",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P43405",
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                    ]
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            ]
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                {
                    "ec_number": "2.7.12.2",
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                    "evidence": [
                        {
                            "id": "P45985",
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                            "url": "https://www.uniprot.org/uniprot/P45985"
                        }
                    ]
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P45985"
                        }
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P46734",
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                            "url": "https://www.uniprot.org/uniprot/P46734"
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                    ]
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                            "url": "https://www.uniprot.org/uniprot/P46734"
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P47809",
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                            "url": "https://www.uniprot.org/uniprot/P47809"
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                    ]
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                {
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P47810",
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                            "url": "https://www.uniprot.org/uniprot/P47810"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "database": "UniProtKB",
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                }
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                    "ec_number": "2.7.10.2",
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                            "url": "https://www.uniprot.org/uniprot/P48025"
                        }
                    ]
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                {
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                            "database": "UniProtKB",
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                    "ec_number": "2.7.12.1",
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                            "id": "P49657",
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                {
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                            "database": "UniProtKB",
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        {
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P49759",
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                            "url": "https://www.uniprot.org/uniprot/P49759"
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                    ]
                },
                {
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49759"
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                            "url": "https://www.uniprot.org/uniprot/P49760"
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                {
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                            "database": "UniProtKB",
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                    "ec_number": "2.7.12.1",
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                {
                    "ec_number": "2.7.12.1",
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                            "url": "https://www.uniprot.org/uniprot/P49761"
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        {
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                {
                    "ec_number": "2.7.11.-",
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                            "url": "https://www.uniprot.org/uniprot/P49762"
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                {
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                {
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                    "ec_number": "2.7.10.2",
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                {
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                    "ec_number": "2.7.10.2",
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                {
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                    "ec_number": "2.7.10.2",
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                            "id": "P52333",
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                {
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                    ]
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                            "id": "P52480",
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                    "ec_number": "2.7.12.2",
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                            "id": "P52564",
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                    ]
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                {
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                            "id": "P52564",
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                    "ec_number": "2.7.10.1",
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                            "id": "P53767",
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                            "id": "P53767",
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                    "ec_number": "2.7.12.2",
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                {
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                {
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    ]
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                {
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                    ]
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P54760",
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                    ]
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P54761",
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                            "url": "https://www.uniprot.org/uniprot/P54761"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54761",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54761"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54762",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54762",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54762"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54762",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54762"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54763",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54763",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54763"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54763",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54763"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54764",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54764",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54764"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54764",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54764"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "P55144",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P55144",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55144"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P55144",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55144"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P55146",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P55146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P55146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55146"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P57097",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P57097",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57097"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P57097",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57097"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P57760",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P57760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57760"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P57760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57760"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P57760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57760"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P58801",
            "gene_name": "Ripk2",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P58801",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P58801"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P58801",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P58801"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P58801",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P58801"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P60710",
            "gene_name": "Actb",
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                {
                    "ec_number": "3.6.4.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P60710",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P60710"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P60766",
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                {
                    "ec_number": "3.6.5.2",
                    "activity": "GTP + H2O = GDP + H(+) + phosphate.",
                    "evidence": [
                        {
                            "id": "P60766",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P60766"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.5.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P60766",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P60766"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P63001",
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                {
                    "ec_number": "3.6.5.2",
                    "activity": "GTP + H2O = GDP + H(+) + phosphate.",
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                        {
                            "id": "P63001",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P63001"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.5.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P63001",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P63001"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P63260",
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                {
                    "ec_number": "3.6.4.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P63260",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P63260"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70236",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P70236",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70236"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70236",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70236"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70424",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P70424",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70424"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70424",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70424"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70451",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P70451",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70451"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70451",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70451"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70600",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P70600",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70600"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70600",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70600"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P83102",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P83102",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P83102"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P83102",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P83102"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "P97504",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P97504",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97504"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P97504",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97504"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "P97523",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P97523",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97523"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P97523",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97523"
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                    ]
                }
            ]
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            "uniprot_ac": "P97793",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P97793",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97793"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P97793",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97793"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00342",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00342",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00342"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00342",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00342"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00495",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00495",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00495"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q00495",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00495"
                        }
                    ]
                }
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        },
        {
            "uniprot_ac": "Q00993",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00993",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00993"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00993",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00993"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01134",
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                {
                    "ec_number": "2.7.1.32",
                    "activity": "ATP + choline = ADP + H(+) + phosphocholine.",
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                        {
                            "id": "Q01134",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01134"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.82",
                    "activity": "ATP + ethanolamine = ADP + H(+) + phosphoethanolamine.",
                    "evidence": [
                        {
                            "id": "Q01134",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01134"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.32",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01134",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01134"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01279",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01279",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01279"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01279",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01279"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01621",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01621",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01621"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01621",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01621"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01887",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01887",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01887"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01887",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01887"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01974",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01974",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01974"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01974",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01974"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01986",
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            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
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                            "url": "https://www.uniprot.org/uniprot/Q01986"
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                            "url": "https://www.uniprot.org/uniprot/Q03142"
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                            "url": "https://www.uniprot.org/uniprot/Q03351"
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                            "id": "Q09147",
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                            "id": "Q12866",
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                {
                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.12.2",
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                {
                    "ec_number": "2.7.12.2",
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                        {
                            "id": "Q13163",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13163"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q13470",
            "gene_name": "TNK1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q13470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q13470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13470"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q13627",
            "gene_name": "DYRK1A",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].",
                    "evidence": [
                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q13882",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q13882",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13882"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q13882",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13882"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q14289",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q14289",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14289"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q14289",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14289"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q14680",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q14680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14680"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q14680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14680"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q14680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14680"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q15303",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q15303",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15303"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q15303",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15303"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q15375",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q15375",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15375"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q15375",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15375"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q15569",
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            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q15569",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15569"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q15569",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15569"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q16288",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q16288",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16288"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q16288",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16288"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q16620",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q16620",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16620"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q16620",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16620"
                        }
                    ]
                }
            ]
        },
        {
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q16832",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16832"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q16832",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16832"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q23977",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q23977",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q23977"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q23977",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q23977"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.-",
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                    "evidence": [
                        {
                            "id": "Q23977",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q23977"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "Q24145",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q24145",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24145"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q24145",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24145"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "Q24324",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q24324",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24324"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q24324",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24324"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q24324",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24324"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q24488",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q24488",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24488"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q24488",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24488"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q24592",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q24592",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24592"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q24592",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24592"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "Q27324",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q27324",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q27324"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q27324",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q27324"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q3UFB7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3UFB7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q3UFB7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3UFB7"
                        }
                    ]
                }
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        {
            "uniprot_ac": "Q498D6",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q498D6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q498D6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                            "id": "Q498D6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q498D6"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "Q4JIM5",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q4JIM5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4JIM5"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q4JIM5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4JIM5"
                        }
                    ]
                }
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        },
        {
            "uniprot_ac": "Q4KM97",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "Q4KM97",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4KM97"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "id": "Q4KM97",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4KM97"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "Q4KSH7",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q4KSH7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4KSH7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
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                            "id": "Q4KSH7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4KSH7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q4V8A3",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
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                            "id": "Q4V8A3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4V8A3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
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                            "id": "Q4V8A3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4V8A3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q501W1",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q501W1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q501W1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
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                            "id": "Q501W1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q501W1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q504Y2",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q504Y2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q504Y2"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q504Y2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q504Y2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54BC9",
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            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q54BC9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54BC9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54BC9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54BC9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54G28",
            "gene_name": "",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q54G28",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54G28"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
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                            "id": "Q54G28",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54G28"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54I36",
            "gene_name": "pyk3",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q54I36",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54I36"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
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                        {
                            "id": "Q54I36",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54I36"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54N73",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q54N73",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54N73"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54N73",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54N73"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54QV3",
            "gene_name": "yakA",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q54QV3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54QV3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54QV3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54QV3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54R58",
            "gene_name": "",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q54R58",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54R58"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54R58",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54R58"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q552C6",
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            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q552C6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q552C6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
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                        {
                            "id": "Q552C6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q552C6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q55CL6",
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            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q55CL6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q55CL6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q55CL6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q55CL6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5FVG7",
            "gene_name": "Srms",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5FVG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5FVG7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5FVG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5FVG7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5JZY3",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5JZY3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5JZY3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5JZY3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5JZY3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5RJI4",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5RJI4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5RJI4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5RJI4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5RJI4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5U2X5",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5U2X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U2X5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "Q5U2X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U2X5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5U2X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U2X5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
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                        {
                            "id": "Q5U2X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U2X5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5U4C9",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5U4C9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U4C9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5U4C9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U4C9"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60629",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60629"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q60629",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60629"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60750",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60750"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q60750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60750"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60751",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60751",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60751"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q60751",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60751"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60805",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60805",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60805"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q60805",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60805"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61006",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61006",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61006"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61006",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61006"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61036",
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                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61036",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61036"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
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                        {
                            "id": "Q61036",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61036"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61144",
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                {
                    "ec_number": "3.4.23.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61144",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61144"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "Q61214",
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                {
                    "ec_number": "2.7.11.23",
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                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "",
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                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61411",
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                {
                    "ec_number": "3.6.5.2",
                    "activity": "GTP + H2O = GDP + H(+) + phosphate.",
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                        {
                            "id": "Q61411",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61411"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.5.2",
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                        {
                            "id": "Q61411",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61411"
                        }
                    ]
                }
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        {
            "uniprot_ac": "Q61526",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61526"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q61526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61526"
                        }
                    ]
                }
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        {
            "uniprot_ac": "Q61527",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61527",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61527"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q61527",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61527"
                        }
                    ]
                }
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        },
        {
            "uniprot_ac": "Q61772",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61772",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61772"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q61772",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61772"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "Q61846",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61846",
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                            "url": "https://www.uniprot.org/uniprot/Q61846"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61846",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61846"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
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                        {
                            "id": "Q61846",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61846"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61851",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61851",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61851"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q61851",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61851"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62120",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62120",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62120"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "Q62120",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62120"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62137",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62137"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "Q62137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62137"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62190",
            "gene_name": "Mst1r",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62190",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62190"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62190",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62190"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62270",
            "gene_name": "Srms",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62270",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62270"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62270",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62270"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62371",
            "gene_name": "Ddr2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62371",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62371"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62371",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62371"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62413",
            "gene_name": "Epha6",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62413",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62413"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62413",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62413"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62662",
            "gene_name": "Frk",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62662",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62662"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62662",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62662"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62689",
            "gene_name": "Jak2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62689",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62689"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62689",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62689"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62799",
            "gene_name": "Erbb3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62799",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62799"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62799",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62799"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62838",
            "gene_name": "Musk",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62838",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62838"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62838",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62838"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62844",
            "gene_name": "Fyn",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62844",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62844"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62844",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62844"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62862",
            "gene_name": "Map2k5",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62862",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62862"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62862",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62862"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62956",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62956",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62956"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62956",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62956"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63116",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63116",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63116"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63116",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63116"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "Q63117",
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            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63117",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63117"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
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                        {
                            "id": "Q63117",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63117"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63132",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63132",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63132"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63132",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63132"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63184",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63184",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63184"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63184",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63184"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63184",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63184"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63272",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63272",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63272"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63272",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63272"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63470",
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            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63474",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63474",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63474"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63474",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63474"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63572",
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            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63572",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63572"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63572",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63572"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63604",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63604"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63604"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63802",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63802",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63802"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63802",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63802"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63932",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63932",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63932"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63932",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63932"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64434",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q64434",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64434"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64434",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64434"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64716",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q64716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64716"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64716"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64725",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q64725",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64725"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64725",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64725"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q66JT0",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q66JT0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q66JT0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "id": "Q66JT0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q66JT0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6J9G0",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6J9G0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6J9G0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6J9G1",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6J9G1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
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                            "id": "Q6J9G1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G1"
                        }
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                }
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        },
        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6P6U0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6P6U0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6P6U0"
                        }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6VNS1"
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q6VNS1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6VNS1"
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q6XUX1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX1"
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                {
                    "ec_number": "2.7.12.1",
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                            "id": "Q6XUX1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX1"
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q6XUX2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX2"
                        }
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                {
                    "ec_number": "2.7.12.1",
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                        {
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX2"
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX3"
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                {
                    "ec_number": "2.7.12.1",
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                            "url": "https://www.uniprot.org/uniprot/Q6XUX3"
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q75JK0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q75JK0"
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                {
                    "ec_number": "2.7.12.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q75JK0"
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q76NV1"
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                {
                    "ec_number": "2.7.12.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q76NV1"
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                    "ec_number": "2.7.10.1",
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                {
                    "ec_number": "2.7.10.1",
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                            "url": "https://www.uniprot.org/uniprot/Q78DX7"
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                    "ec_number": "2.7.10.1",
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                {
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                {
                    "ec_number": "2.7.10.1",
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                {
                    "ec_number": "2.7.11.1",
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                {
                    "ec_number": "2.7.10.2",
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                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                {
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                {
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                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
                    "ec_number": "2.7.12.1",
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                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
                    "ec_number": "2.7.10.2",
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        {
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                {
                    "ec_number": "2.7.12.1",
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        {
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                },
                {
                    "ec_number": "2.7.10.2",
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                    ]
                },
                {
                    "ec_number": "2.7.10.-",
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                            "url": "https://www.uniprot.org/uniprot/Q9I7F7"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9JJ78",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q9JJ78",
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                            "url": "https://www.uniprot.org/uniprot/Q9JJ78"
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                    ]
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                {
                    "ec_number": "2.7.12.2",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JJ78"
                        }
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                {
                    "ec_number": "2.7.12.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9NR20"
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                    ]
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                {
                    "ec_number": "2.7.12.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9NR20"
                        }
                    ]
                }
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        {
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                {
                    "ec_number": "3.6.5.2",
                    "activity": "GTP + H2O = GDP + H(+) + phosphate.",
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                            "id": "Q9QUI0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9QUI0"
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                    ]
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                {
                    "ec_number": "3.6.5.2",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9QUI0"
                        }
                    ]
                }
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9QVP9"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "url": "https://www.uniprot.org/uniprot/Q9QVP9"
                        }
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
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                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                        }
                    ]
                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q9UF33",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9UF33"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9UF33"
                        }
                    ]
                }
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        },
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q9UIG0",
                            "database": "UniProtKB",
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                        }
                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q9UIG0",
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                        }
                    ]
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9UM73"
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                    ]
                }
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                    "ec_number": "2.7.12.1",
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                            "id": "Q9V3D5",
                            "database": "UniProtKB",
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                        }
                    ]
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                {
                    "ec_number": "2.7.12.1",
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                            "url": "https://www.uniprot.org/uniprot/Q9V3D5"
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                    "ec_number": "2.7.10.1",
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                {
                    "ec_number": "2.7.10.1",
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