{
    "uniprot_canonical_ac": "Q8BLU0-1",
    "uniprot_ac": "Q8BLU0",
    "uniprot_id": "FLRT2_MOUSE",
    "mass": {
        "chemical_mass": 73948.0,
        "monoisotopic_mass": 73948.0
    },
    "refseq": {
        "ac": "NP_958926",
        "name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958926"
    },
    "gene_names": [
        {
            "name": "Flrt2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8BLU0",
            "id": "Q8BLU0"
        },
        {
            "name": "Flrt2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958926",
            "id": "NP_958926"
        },
        {
            "name": "Kiaa0405",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8BLU0",
            "id": "Q8BLU0"
        }
    ],
    "protein_names": [
        {
            "name": "Leucine-rich repeat transmembrane protein FLRT2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8BLU0"
        },
        {
            "name": "Fibronectin leucine rich transmembrane protein 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8BLU0"
        },
        {
            "name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958926",
            "id": "NP_958926"
        },
        {
            "name": "leucine-rich repeat transmembrane protein FLRT2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958926",
            "id": "NP_958926"
        }
    ],
    "function": [
        {
            "annotation": "FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome in embryo",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_958926",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958926"
                },
                {
                    "database": "PubMed",
                    "id": "16872596",
                    "url": "https://glygen.org/publication/PubMed/16872596"
                }
            ]
        },
        {
            "annotation": "Fibronectin leucine-rich transmembrane protein 2 drives monocyte differentiation into macrophages via the UNC5B-Akt/mTOR axis. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_958926",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958926"
                },
                {
                    "database": "PubMed",
                    "id": "37090697",
                    "url": "https://glygen.org/publication/PubMed/37090697"
                }
            ]
        },
        {
            "annotation": "Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:21350012, PubMed:25728924, PubMed:25374360). May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D (PubMed:21673655). Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members (PubMed:21673655, PubMed:25728924). Plays a role in fibroblast growth factor-mediated signaling cascades (PubMed:16872596). Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis (PubMed:21350012).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0#function"
                },
                {
                    "database": "PubMed",
                    "id": "21350012",
                    "url": "https://glygen.org/publication/PubMed/21350012"
                },
                {
                    "database": "PubMed",
                    "id": "25374360",
                    "url": "https://glygen.org/publication/PubMed/25374360"
                },
                {
                    "database": "PubMed",
                    "id": "16872596",
                    "url": "https://glygen.org/publication/PubMed/16872596"
                },
                {
                    "database": "PubMed",
                    "id": "21673655",
                    "url": "https://glygen.org/publication/PubMed/21673655"
                },
                {
                    "database": "PubMed",
                    "id": "25728924",
                    "url": "https://glygen.org/publication/PubMed/25728924"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [
        {
            "start_pos": 170,
            "end_pos": 170,
            "sequence_org": "H",
            "sequence_mut": "E",
            "comment": "Abolishes interaction with UNC5D.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                },
                {
                    "database": "PubMed",
                    "id": "25374360",
                    "url": "https://glygen.org/publication/PubMed/25374360"
                }
            ]
        },
        {
            "start_pos": 170,
            "end_pos": 170,
            "sequence_org": "H",
            "sequence_mut": "N",
            "comment": "Abolishes interaction with UNC5D.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                },
                {
                    "database": "PubMed",
                    "id": "25374360",
                    "url": "https://glygen.org/publication/PubMed/25374360"
                }
            ]
        },
        {
            "start_pos": 186,
            "end_pos": 186,
            "sequence_org": "R",
            "sequence_mut": "N",
            "comment": "Abolishes homooligomerization and FLRT2-mediated cell-cell adhesion; when associated with T-188.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                },
                {
                    "database": "PubMed",
                    "id": "25374360",
                    "url": "https://glygen.org/publication/PubMed/25374360"
                }
            ]
        },
        {
            "start_pos": 188,
            "end_pos": 188,
            "sequence_org": "D",
            "sequence_mut": "T",
            "comment": "Abolishes homooligomerization and FLRT2-mediated cell-cell adhesion; when associated with N-186.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                },
                {
                    "database": "PubMed",
                    "id": "25374360",
                    "url": "https://glygen.org/publication/PubMed/25374360"
                }
            ]
        },
        {
            "start_pos": 248,
            "end_pos": 248,
            "sequence_org": "D",
            "sequence_mut": "N",
            "comment": "No effect on interaction with UNC5D; when associated with T-250.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                },
                {
                    "database": "PubMed",
                    "id": "25374360",
                    "url": "https://glygen.org/publication/PubMed/25374360"
                }
            ]
        },
        {
            "start_pos": 250,
            "end_pos": 250,
            "sequence_org": "P",
            "sequence_mut": "T",
            "comment": "No effect on interaction with UNC5D; when associated with N-248.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                },
                {
                    "database": "PubMed",
                    "id": "25374360",
                    "url": "https://glygen.org/publication/PubMed/25374360"
                }
            ]
        }
    ],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Flrt2",
            "url": "https://www.uniprot.org/uniprot/Q8BLU0",
            "locus": {
                "chromosome": "12",
                "start_pos": 95751989,
                "end_pos": 95659000,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000047414",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000047414"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000047414",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000047414",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "399558",
            "url": "https://www.ncbi.nlm.nih.gov/gene/399558",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q8BLU0",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q8BLU0*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR000372",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR000483",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001611",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003591",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003961",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR032675",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036116",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:399558",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:399558",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "3603594",
            "url": "http://www.informatics.jax.org/marker/MGI:3603594",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "TWARMEP",
            "url": "https://omabrowser.org/oma/group/TWARMEP/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2916435at2759",
            "url": "http://www.orthodb.org/?query=2916435at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR45712",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR45712:SF16",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF16",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4V2C",
            "url": "https://www.rcsb.org/structure/4V2C",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "4V2D",
            "url": "https://www.rcsb.org/structure/4V2D",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "5FTT",
            "url": "https://www.rcsb.org/structure/5FTT",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "5FTU",
            "url": "https://www.rcsb.org/structure/5FTU",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "PF01463",
            "url": "http://pfam.xfam.org/family/PF01463",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13855",
            "url": "http://pfam.xfam.org/family/PF13855",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8BLU0",
            "url": "http://purl.obolibrary.org/obo/PR_Q8BLU0",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-5654687",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5654687",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_958926",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958926",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BLU0",
            "url": "https://www.uniprot.org/uniprot/Q8BLU0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BLU0-1",
            "url": "https://www.uniprot.org/uniprot/Q8BLU0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MGLQTTKWPGRGAFILKFWLIISLGLYLQVSKLLACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTPGLPVFTPAPSTVSPTTQSPTLSVPSPSRGSVPPAPTPSKLPTIPDWDGRERVTPPISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSLVNLEPRSTYRICLVPLDAFNYRTVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSPFLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSILEMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT",
        "length": 660,
        "header": "sp|Q8BLU0-1|FLRT2_MOUSE Isoform 1 of Leucine-rich repeat transmembrane protein FLRT2  OS=Mus musculus OX=10090 GN=Flrt2 PE=1 SV=1 CANONICAL=Q8BLU0-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q8BLU0-1",
            "url": "",
            "sequence": {
                "sequence": "MGLQTTKWPGRGAFILKFWLIISLGLYLQVSKLLACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTPGLPVFTPAPSTVSPTTQSPTLSVPSPSRGSVPPAPTPSKLPTIPDWDGRERVTPPISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSLVNLEPRSTYRICLVPLDAFNYRTVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSPFLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSILEMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT",
                "length": 660,
                "header": "sp|Q8BLU0-1|FLRT2_MOUSE Isoform 1 of Leucine-rich repeat transmembrane protein FLRT2  OS=Mus musculus OX=10090 GN=Flrt2 PE=1 SV=1 CANONICAL=Q8BLU0-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 95747643,
                "end_pos": 95745664,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000057324",
                        "url": "https://www.ensembl.org/id/ENSMUST00000057324"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000062171",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000062171"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 202,
            "start_aa": "Asn",
            "end_pos": 202,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn202",
            "evidence": [
                {
                    "id": "Q8BLU0",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development.",
            "journal": "Dev. Biol.",
            "date": "2006",
            "authors": "Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_958926",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958926"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16872596",
                    "url": "https://glygen.org/publication/PubMed/16872596"
                }
            ]
        },
        {
            "title": "Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3.",
            "journal": "Dev. Biol.",
            "date": "2008",
            "authors": "Maretto S, Muller PS, Aricescu AR, Cho KW, Bikoff EK, Robertson EJ",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18448090",
                    "url": "https://glygen.org/publication/PubMed/18448090"
                }
            ]
        },
        {
            "title": "The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.",
            "journal": "Development",
            "date": "2011",
            "authors": "Muller PS, Schulz R, Maretto S, Costello I, Srinivas S, Bikoff E, Robertson E",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "21350012",
                    "url": "https://glygen.org/publication/PubMed/21350012"
                }
            ]
        },
        {
            "title": "FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.",
            "journal": "EMBO J.",
            "date": "2011",
            "authors": "Yamagishi S, Hampel F, Hata K, Del Toro D, Schwark M, Kvachnina E, Bastmeyer M, Yamashita T, Tarabykin V, Klein R, Egea J",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "21673655",
                    "url": "https://glygen.org/publication/PubMed/21673655"
                }
            ]
        },
        {
            "title": "Mouse FLRT2 interacts with the extracellular and intracellular regions of FGFR2.",
            "journal": "J. Dent. Res.",
            "date": "2011",
            "authors": "Wei K., Xu Y., Manolson M.F., Gong S.G., Tse H.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "21765038",
                    "url": "https://glygen.org/publication/PubMed/21765038"
                }
            ]
        },
        {
            "title": "FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development.",
            "journal": "Neuron",
            "date": "2012",
            "authors": "O'Sullivan ML, de Wit J, Savas JN, Comoletti D, Otto-Hitt S, Yates JR 3rd, Ghosh A",
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                    "type": "PubMed",
                    "id": "22405201",
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                }
            ]
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        {
            "title": "FLRT2 interacts with fibronectin in the ATDC5 chondroprogenitor cells.",
            "journal": "J. Cell. Physiol.",
            "date": "2014",
            "authors": "Gong S.G., Arudchelvan Y., Flintoff K.A.",
            "evidence": [
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                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
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                {
                    "type": "PubMed",
                    "id": "24585683",
                    "url": "https://glygen.org/publication/PubMed/24585683"
                }
            ]
        },
        {
            "title": "FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.",
            "journal": "Neuron",
            "date": "2014",
            "authors": "Seiradake E, del Toro D, Nagel D, Cop F, Hartl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R",
            "evidence": [
                {
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                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                }
            ],
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                {
                    "type": "PubMed",
                    "id": "25374360",
                    "url": "https://glygen.org/publication/PubMed/25374360"
                }
            ]
        },
        {
            "title": "Structural basis of latrophilin-FLRT interaction.",
            "journal": "Structure",
            "date": "2015",
            "authors": "Jackson VA, del Toro D, Carrasquero M, Roversi P, Harlos K, Klein R, Seiradake E",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BLU0",
                    "url": "https://www.uniprot.org/uniprot/Q8BLU0"
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            "reference": [
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                    "type": "PubMed",
                    "id": "25728924",
                    "url": "https://glygen.org/publication/PubMed/25728924"
                }
            ]
        },
        {
            "title": "Fibronectin leucine-rich transmembrane protein 2 drives monocyte differentiation into macrophages via the UNC5B-Akt/mTOR axis.",
            "journal": "Frontiers in immunology",
            "date": "2023",
            "authors": "Fang Yaxiong, Ma Kongyang, Huang Yi-Min, Dang Yuanye, Liu Zhaoyu, Xu Yiming, Zheng Xi-Long, Yang Xiangdong, Huo Yongliang, Dai Xiaoyan",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_958926",
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        {
            "id": "mmu:399558",
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        {
            "id": "R-MMU-5654687",
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        {
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                "length": 660
            },
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                    "id": "45231034",
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        },
        {
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            "tax_id": 9606,
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                "length": 660
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                }
            ],
            "common_name": "Human"
        }
    ],
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                "total": 7,
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                        "id": "GO:0005615",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615",
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                                "id": "Q8BLU0",
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                            }
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                                "id": "Q8BLU0",
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                    {
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                                "id": "Q8BLU0",
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                            }
                        ],
                        "pmid": ""
                    },
                    {
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                                "id": "Q8BLU0",
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                    {
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                                "id": "Q8BLU0",
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                            }
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                                "id": "Q8BLU0",
                                "url": "https://www.uniprot.org/uniprot/Q8BLU0"
                            }
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                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 7,
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                    {
                        "name": "heart morphogenesis",
                        "id": "GO:0003007",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007",
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                                "id": "Q8BLU0",
                                "url": "https://www.uniprot.org/uniprot/Q8BLU0"
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                    {
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                    {
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                                "id": "Q8BLU0",
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                            }
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                        "pmid": ""
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                    {
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                                "id": "Q8BLU0",
                                "url": "https://www.uniprot.org/uniprot/Q8BLU0"
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                    {
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                                "id": "Q8BLU0",
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                        "pmid": ""
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                "total": 2,
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                        "name": "chemorepellent activity",
                        "id": "GO:0045499",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499",
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                                "id": "Q8BLU0",
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                    {
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                                "id": "Q8BLU0",
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