{
    "uniprot_canonical_ac": "Q8BIR2-1",
    "uniprot_ac": "Q8BIR2",
    "uniprot_id": "ASTE1_MOUSE",
    "mass": {
        "chemical_mass": 76370.0,
        "monoisotopic_mass": 76370.0
    },
    "refseq": {
        "ac": "NP_001158300",
        "name": "protein asteroid homolog 1 isoform 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001158300"
    },
    "gene_names": [
        {
            "name": "Aste1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8BIR2",
            "id": "Q8BIR2"
        },
        {
            "name": "1100001A21Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079927",
            "id": "NP_079927"
        },
        {
            "name": "Aste1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079927",
            "id": "NP_079927"
        }
    ],
    "protein_names": [
        {
            "name": "Protein asteroid homolog 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8BIR2"
        },
        {
            "name": "protein asteroid homolog 1 isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079927",
            "id": "NP_079927"
        },
        {
            "name": "protein asteroid homolog 1 isoform 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001158300",
            "id": "NP_001158300"
        },
        {
            "name": "protein asteroid homolog 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001158300",
            "id": "NP_001158300"
        }
    ],
    "function": [
        {
            "annotation": "Possible role in EGF receptor signaling.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BIR2",
                    "url": "https://www.uniprot.org/uniprot/Q8BIR2#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0112182",
            "recommended_name": {
                "id": "DOID:0112182",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0112182",
                "name": "mismatch repair cancer syndrome",
                "description": "A syndrome characterized by predisposition for development of a broad spectrum of malignancies during childhood, including mainly brain, hematological and gastrointestinal cancers that has_material_basis_in homozygous or compound heterozygous mutation in the mismatch repair genes MLH1, MSH2, MSH6, or PMS2 on chromosomes 3p22.2, 2p21-p16, 2p16.3, and 7p22.1, respectively."
            },
            "synonyms": [
                {
                    "id": "DOID:0112182",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112182",
                    "name": "BTP1 syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0112182",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112182",
                    "name": "BTPS1",
                    "description": ""
                },
                {
                    "id": "DOID:0112182",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112182",
                    "name": "CMMRDS",
                    "description": ""
                },
                {
                    "id": "DOID:0112182",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112182",
                    "name": "MMR deficiency",
                    "description": ""
                },
                {
                    "id": "DOID:0112182",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112182",
                    "name": "Turcot syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0112182",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112182",
                    "name": "CMMR-D syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0112182",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112182",
                    "name": "brain tumor-polyposis syndrome 1",
                    "description": ""
                },
                {
                    "id": "DOID:0112182",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112182",
                    "name": "childhood cancer syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0112182",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112182",
                    "name": "constitutional mismatch repair deficiency syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "mismatch repair cancer syndrome 1",
                    "description": "A rare childhood cancer predisposition syndrome caused by biallelic inheritance of mutations in MLH1, MSH2, MSH6, or PMS2 genes. It is characterized by the development of childhood cancers, usually hematological malignancies and/or brain tumors, and colorectal cancers with multiple intestinal polyps. The majority of patients show signs of neurofibromatosis type 1."
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "BTP1 syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "CMMR-D",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "CMMR-D syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "MMRCS1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "brain tumor-polyposis syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "constitutional MIS-match repair deficiency syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "constitutional mismatch repair deficiency syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "mismatch repair cancer syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "CNS tumors with familial polyposis of the colon",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "CNS tumours with familial polyposis of the colon",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "MMR deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "MMRCS",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "Turcot syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "brain tumor-polyposis syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "childhood cancer syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "glioma-polyposis syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "malignant tumors of the central nervous system associated with familial polyposis of the colon",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "malignant tumours of the central nervous system associated with familial polyposis of the colon",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "mismatch repair cancer syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010159",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010159",
                    "name": "mismatch repair deficiency",
                    "description": ""
                },
                {
                    "id": "MIM:276300",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/276300",
                    "name": "Mismatch repair cancer syndrome 1",
                    "description": "Mismatch repair cancer syndrome 1"
                }
            ],
            "evidence": [
                {
                    "id": "0112182",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0112182"
                }
            ]
        },
        {
            "disease_id": "DOID:3883",
            "recommended_name": {
                "id": "DOID:3883",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3883",
                "name": "Lynch syndrome",
                "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers."
            },
            "synonyms": [
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "COCA 1",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "HNPCC - hereditary nonpolyposis colon cancer",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "Hereditary Defective Mismatch Repair syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "hereditary nonpolyposis colorectal cancer",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "hereditary nonpolyposis colorectal neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "Hereditary non-polyposis colon cancer",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "Hereditary non-polyposis colon cancer syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "Hereditary non-polyposis colorectal cancer",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "Hereditary nonpolyposis colon cancer",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "Hereditary nonpolyposis colon cancer syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "Hereditary nonpolyposis colorectal cancer syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:3883",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3883",
                    "name": "Hereditary non-polyposis colorectal cancer syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "Lynch syndrome 1",
                    "description": "Any Lynch syndrome in which the cause of the disease is a mutation in the MSH2 gene."
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "HNPCC1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "Hereditary non-polyposis colon cancer type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "Lynch 1 syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "Lynch syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "Lynch syndrome type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "familial non-polyposis colon cancer type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "hereditary nonpolyposis colorectal cancer type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "COCA1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "LYNCH syndrome I",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "Lynch syndrome 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "colon cancer, familial nonpolyposis, type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007356",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007356",
                    "name": "colorectal cancer, hereditary nonpolyposis, type 1",
                    "description": ""
                },
                {
                    "id": "MIM:120435",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/120435",
                    "name": "Lynch syndrome 1",
                    "description": "Lynch syndrome 1"
                }
            ],
            "evidence": [
                {
                    "id": "3883",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3883"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BIR2",
                    "url": "https://www.uniprot.org/uniprot/Q8BIR2"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Aste1",
            "url": "https://www.uniprot.org/uniprot/Q8BIR2",
            "locus": {
                "chromosome": "9",
                "start_pos": 105289428,
                "end_pos": 105272591,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000032567",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000032567"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000032567",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000032567",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "66595",
            "url": "https://www.ncbi.nlm.nih.gov/gene/66595",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR026832",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR026832",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR029060",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029060",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR039436",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039436",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:66595",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:66595",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1913845",
            "url": "http://www.informatics.jax.org/marker/MGI:1913845",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "FRRGGDY",
            "url": "https://omabrowser.org/oma/group/FRRGGDY/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2943058at2759",
            "url": "http://www.orthodb.org/?query=2943058at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR15665",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15665",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR15665:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15665:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF12813",
            "url": "http://pfam.xfam.org/family/PF12813",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8BIR2",
            "url": "http://purl.obolibrary.org/obo/PR_Q8BIR2",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_079927",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079927",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A087WNN6",
            "url": "https://www.uniprot.org/uniprot/A0A087WNN6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A087WNN6-1",
            "url": "https://www.uniprot.org/uniprot/A0A087WNN6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q1A4",
            "url": "https://www.uniprot.org/uniprot/E9Q1A4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q1A4-1",
            "url": "https://www.uniprot.org/uniprot/E9Q1A4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BKA9",
            "url": "https://www.uniprot.org/uniprot/H3BKA9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BKA9-1",
            "url": "https://www.uniprot.org/uniprot/H3BKA9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BLN7",
            "url": "https://www.uniprot.org/uniprot/H3BLN7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BLN7-1",
            "url": "https://www.uniprot.org/uniprot/H3BLN7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BIR2",
            "url": "https://www.uniprot.org/uniprot/Q8BIR2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BIR2-1",
            "url": "https://www.uniprot.org/uniprot/Q8BIR2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BIR2-2",
            "url": "https://www.uniprot.org/uniprot/Q8BIR2-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MGIRGLMSFVEDYSNEFFVDLKLRNTKLIIDGYSLFHRLCFNSDLELRYGGDYDLFADVVQKFFESLFVCHICPYVVLDGGCDISDKKLTTLKDRAKEKIQAARSLSLGGGGNVCPLLIREVFIQVLIRLEVCFVQSFSEADRDIMTLANHWNCPVLSSDSDFCIFDLRSGFCSLNSFQWRNLNTIKDTQDYYIPARSFSLNAFCHYFNNMNKALLPLFAVLCGNDHVNLPIMDTFISKVRLPLSSKGRRYHRVLGLLNWLSHFDDPTEALDNVLKSLPKKSRENVKELLCCSMEEYQQSPVKLQDFFQYGSYVCTDASDLGLPEWVLGALAKGQLPPFISDALVLRRTFLHTQVENMQRPNAHRISQPIRQIIYGLLLNGPSHAEDIAQNTLPSQLLAFNEVERIDTNIKTSTVYAKQLLKDQCDLSKLAELPLARRQMLLLEALKVKQVVLESIPTFLKLPIAVTCYWLQSTEAKAKLHHLQALLLGMLREPLHAIVNSPGTEDPQRGGAKMLYEELCQVKAPMRPGPRVDLDTAHVFCQWQSCLQMGLYLNQLLSTPLPEPNLTWLYNGSLVHRLCQQLPASSSVESLLSLCPEAKQLYEHLFNATKSYAPAELFLPKTKSKSKKKRQKKKVASLGTTADAKHWYDRSNRFGPLMPESLEEHVENSELE",
        "length": 672,
        "header": "sp|Q8BIR2-1|ASTE1_MOUSE Isoform 1 of Protein asteroid homolog 1  OS=Mus musculus OX=10090 GN=Aste1 PE=2 SV=1 CANONICAL=Q8BIR2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A087WNN6-1",
            "url": "",
            "sequence": {
                "sequence": "MGIRGLMSFVEDYSNEFFVDLKLRNTKLIIDGYSLFHRLCFNSDLELSSPWLGGRCFS",
                "length": 58,
                "header": "tr|A0A087WNN6-1|ASTE1_MOUSE Computationally mapped isoform of Protein asteroid homolog 1  OS=Mus musculus OX=10090 GN=Aste1 PE=2 SV=1 CANONICAL=Q8BIR2-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 105278705,
                "end_pos": 105273762,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000176350.5",
                        "url": "https://www.ensembl.org/id/ENSMUST00000176350.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000139429.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000139429.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "E9Q1A4-1",
            "url": "",
            "sequence": {
                "sequence": "MLYEELCQVKAPMRPGPRVDLDTAHVFCQWQSCLQMGLYLNQLLSTPLPEPNLTWLYNGSLVHRLCQQLPASSSVESLLSLCPEAKQLYEHLFNATKSYAPAELFLPKTKSKSKKKRQKKKVASLGTTADAKHWYDRSNRFGPLMPESLEEHVENSELE",
                "length": 159,
                "header": "tr|E9Q1A4-1|ASTE1_MOUSE Computationally mapped isoform of Protein asteroid homolog 1  OS=Mus musculus OX=10090 GN=Aste1 PE=2 SV=1 CANONICAL=Q8BIR2-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 105282510,
                "end_pos": 105280627,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000167674.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000167674.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000131164.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000131164.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "H3BKA9-1",
            "url": "",
            "sequence": {
                "sequence": "KQLLKDQCDLSKLAELPLARRQMLLLEALKVKQVVLESIPTFLKLPIAVTCYWLQSTEAKAKLHHLQALLLGMLREPLHAIVNSPGNVDSAPRQAQCLAPRYL",
                "length": 103,
                "header": "tr|H3BKA9-1|H3BKA9_MOUSE Computationally mapped isoform of Asteroid homolog 1  OS=Mus musculus OX=10090 GN=Aste1 PE=4 SV=1 CANONICAL=Q8BIR2-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 105279969,
                "end_pos": 105275013,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000177402.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000177402.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000135318.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000135318.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "H3BLN7-1",
            "url": "",
            "sequence": {
                "sequence": "MGIRGLMSFVEDYSNEFFVDLKLRNTKLIIDGYSLFHRLCFNSDLELRYGGDYDLFADVVQKFFESLFVCHICPYVVLDGGCDISDKKLTTLKDRAKEKIQAARSLSLGGGGNVCPLLIREVFIQVLIRLEVCFVQSFSEADRDIMTLANHWNCPVLSSDSDFCIFDLRSGFCSLNSFQWRNLNTIKDTQDYYIPARSFSLNAFCHYFNNMNKALLPLFAVLCGNDHVNLPIMDTFISKVRLPLSSKGRRYHRVLGLLNWLSHFDDPTEALDNVLKSLPKKSRENVKELLCCSMEEYQQSPVKLQDFFQYGSYVCTDASDLVL",
                "length": 323,
                "header": "tr|H3BLN7-1|H3BLN7_MOUSE Computationally mapped isoform of Asteroid homolog 1  OS=Mus musculus OX=10090 GN=Aste1 PE=3 SV=2 CANONICAL=Q8BIR2-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 105282256,
                "end_pos": 105273762,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000176940.3",
                        "url": "https://www.ensembl.org/id/ENSMUST00000176940.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000135856.3",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000135856.3"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8BIR2-1",
            "url": "",
            "sequence": {
                "sequence": "MGIRGLMSFVEDYSNEFFVDLKLRNTKLIIDGYSLFHRLCFNSDLELRYGGDYDLFADVVQKFFESLFVCHICPYVVLDGGCDISDKKLTTLKDRAKEKIQAARSLSLGGGGNVCPLLIREVFIQVLIRLEVCFVQSFSEADRDIMTLANHWNCPVLSSDSDFCIFDLRSGFCSLNSFQWRNLNTIKDTQDYYIPARSFSLNAFCHYFNNMNKALLPLFAVLCGNDHVNLPIMDTFISKVRLPLSSKGRRYHRVLGLLNWLSHFDDPTEALDNVLKSLPKKSRENVKELLCCSMEEYQQSPVKLQDFFQYGSYVCTDASDLGLPEWVLGALAKGQLPPFISDALVLRRTFLHTQVENMQRPNAHRISQPIRQIIYGLLLNGPSHAEDIAQNTLPSQLLAFNEVERIDTNIKTSTVYAKQLLKDQCDLSKLAELPLARRQMLLLEALKVKQVVLESIPTFLKLPIAVTCYWLQSTEAKAKLHHLQALLLGMLREPLHAIVNSPGTEDPQRGGAKMLYEELCQVKAPMRPGPRVDLDTAHVFCQWQSCLQMGLYLNQLLSTPLPEPNLTWLYNGSLVHRLCQQLPASSSVESLLSLCPEAKQLYEHLFNATKSYAPAELFLPKTKSKSKKKRQKKKVASLGTTADAKHWYDRSNRFGPLMPESLEEHVENSELE",
                "length": 672,
                "header": "sp|Q8BIR2-1|ASTE1_MOUSE Isoform 1 of Protein asteroid homolog 1  OS=Mus musculus OX=10090 GN=Aste1 PE=2 SV=1 CANONICAL=Q8BIR2-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 105282510,
                "end_pos": 105273762,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000035181",
                        "url": "https://www.ensembl.org/id/ENSMUST00000035181"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000035181",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000035181"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8BIR2-2",
            "url": "",
            "sequence": {
                "sequence": "MAILSSTDFASILTWSSDGGCDISDKKLTTLKDRAKEKIQAARSLSLGGGGNVCPLLIREVFIQVLIRLEVCFVQSFSEADRDIMTLANHWNCPVLSSDSDFCIFDLRSGFCSLNSFQWRNLNTIKDTQDYYIPARSFSLNAFCHYFNNMNKALLPLFAVLCGNDHVNLPIMDTFISKVRLPLSSKGRRYHRVLGLLNWLSHFDDPTEALDNVLKSLPKKSRENVKELLCCSMEEYQQSPVKLQDFFQYGSYVCTDASDLGLPEWVLGALAKGQLPPFISDALVLRRTFLHTQVENMQRPNAHRISQPIRQIIYGLLLNGPSHAEDIAQNTLPSQLLAFNEVERIDTNIKTSTVYAKQLLKDQCDLSKLAELPLARRQMLLLEALKVKQVVLESIPTFLKLPIAVTCYWLQSTEAKAKLHHLQALLLGMLREPLHAIVNSPGTEDPQRGGAKMLYEELCQVKAPMRPGPRVDLDTAHVFCQWQSCLQMGLYLNQLLSTPLPEPNLTWLYNGSLVHRLCQQLPASSSVESLLSLCPEAKQLYEHLFNATKSYAPAELFLPKTKSKSKKKRQKKKVASLGTTADAKHWYDRSNRFGPLMPESLEEHVENSELE",
                "length": 611,
                "header": "sp|Q8BIR2-2|ASTE1_MOUSE Isoform 2 of Protein asteroid homolog 1  OS=Mus musculus OX=10090 GN=Aste1 PE=2 SV=1 CANONICAL=Q8BIR2-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 105282510,
                "end_pos": 105273853,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000123807",
                        "url": "https://www.ensembl.org/id/ENSMUST00000123807"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000149596",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000149596"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:66595",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:66595",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q2TB18-1",
            "protein_name": "Protein asteroid homolog 1",
            "gene_name": "ASTE1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MGIRGLMSFVEDHSNEFFTDLKLRDTKIVIDGYALFHRLCFSSNLDLRYGGDYDSFADVVQKFFESLFACNICPYVVLDGGCDISDKKLTTLKDRAREKIQMAHSLSVGGSGYVCPLLIREVFIQVLIKLRVCFVQCFSEADRDIMTLANHWNCPVLSSDSDFCIFDLKTGFCPLNSFQWRNMNTIKGTQNYIPAKCFSLDAFCHHFSNMNKALLPLFAVLCGNDHVNLPIMETFLSKARLPLGATSSKGRRHHRILGLLNWLSHFANPTEALDNVLKYLPKKDRENVKELLCCSMEEYQQSQVKLQDFFQCGTYVCPDALNLGLPEWVLVALAKGQLSPFISDALVLRRTILPTQVENMQQPNAHRISQPIRQIIYGLLLNASPHLDKTSWNALPPQPLAFSEVERINKNIRTSIIDAVELAKDHSDLSRLTELSLRRRQMLLLETLKVKQTILEPIPTSLKLPIAVSCYWLQHTETKAKLHHLQSLLLTMLVGPLIAIINSPGKEELQEDGAKMLYAEFQRVKAQTRLGTRLDLDTAHIFCQWQSCLQMGMYLNQLLSTPLPEPDLTRLYSGSLVHGLCQQLLASTSVESLLSICPEAKQLYEYLFNATRSYAPAEIFLPKGRSNSKKKRQKKQNTSCSKNRGRTTAHTKCWYEGNNRFGLLMVENLEEHSEASNIE",
                "length": 679
            },
            "evidence": [
                {
                    "id": "45233995",
                    "url": "http://www.informatics.jax.org/homology/45233995",
                    "database": "MGI"
                },
                {
                    "id": "Q8BIR2",
                    "url": "https://omabrowser.org/oma/group/Q8BIR2/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {},
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 565,
            "end_pos": 567,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 571,
            "end_pos": 573,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 607,
            "end_pos": 609,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}