{
    "uniprot_canonical_ac": "Q8BI36-1",
    "uniprot_ac": "Q8BI36",
    "uniprot_id": "JKAMP_MOUSE",
    "mass": {
        "chemical_mass": 35248.0,
        "monoisotopic_mass": 35248.0
    },
    "refseq": {
        "ac": "NP_001191996",
        "name": "JNK1/MAPK8-associated membrane protein isoform 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996"
    },
    "gene_names": [
        {
            "name": "Jkamp",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8BI36",
            "id": "Q8BI36"
        },
        {
            "name": "1200003C05Rik; 2310047L11Rik; Jamp",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996",
            "id": "NP_001191996"
        },
        {
            "name": "Jamp",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8BI36",
            "id": "Q8BI36"
        },
        {
            "name": "Jkamp",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996",
            "id": "NP_001191996"
        }
    ],
    "protein_names": [
        {
            "name": "JNK1/MAPK8-associated membrane protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8BI36"
        },
        {
            "name": "JAMP",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8BI36"
        },
        {
            "name": "JKAMP",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8BI36"
        },
        {
            "name": "JNK1-associated membrane protein",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8BI36"
        },
        {
            "name": "JNK1/MAPK8-associated membrane protein isoform 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996",
            "id": "NP_001191996"
        },
        {
            "name": "Medulloblastoma antigen MU-MB-50.4 homolog",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8BI36"
        },
        {
            "name": "medulloblastoma antigen MU-MB-50.4 homolog",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996",
            "id": "NP_001191996"
        }
    ],
    "function": [
        {
            "annotation": "C-Jun NH2 -Terminal Protein Kinase Phosphorylates the Nrf2-ECH Homology 6 Domain of Nuclear Factor Erythroid 2-Related Factor 2 and Downregulates Cytoprotective Genes in Acetaminophen-Induced Liver Injury in Mice.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001191996",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996"
                },
                {
                    "database": "PubMed",
                    "id": "31945188",
                    "url": "https://glygen.org/publication/PubMed/31945188"
                }
            ]
        },
        {
            "annotation": "JAMP is a membrane-anchored regulator of the duration of JNK1 activity in response to diverse stress stimuli [JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein]",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001191996",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996"
                },
                {
                    "database": "PubMed",
                    "id": "16166642",
                    "url": "https://glygen.org/publication/PubMed/16166642"
                }
            ]
        },
        {
            "annotation": "JAMP is an important component for coordinated clearance of misfolded proteins from the endoplasmic reticulum.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001191996",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996"
                },
                {
                    "database": "PubMed",
                    "id": "18784250",
                    "url": "https://glygen.org/publication/PubMed/18784250"
                }
            ]
        },
        {
            "annotation": "JKAMP inhibits the osteogenic capacity of adipose-derived stem cells in diabetic osteoporosis by modulating the Wnt signaling pathway through intragenic DNA methylation. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001191996",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996"
                },
                {
                    "database": "PubMed",
                    "id": "33579371",
                    "url": "https://glygen.org/publication/PubMed/33579371"
                }
            ]
        },
        {
            "annotation": "May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BI36",
                    "url": "https://www.uniprot.org/uniprot/Q8BI36#function"
                },
                {
                    "database": "PubMed",
                    "id": "16166642",
                    "url": "https://glygen.org/publication/PubMed/16166642"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [
        {
            "start_pos": 24,
            "end_pos": 24,
            "sequence_org": "S",
            "sequence_mut": "A",
            "comment": "Loss of glycosylation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BI36",
                    "url": "https://www.uniprot.org/uniprot/Q8BI36"
                },
                {
                    "database": "PubMed",
                    "id": "16166642",
                    "url": "https://glygen.org/publication/PubMed/16166642"
                }
            ]
        }
    ],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BI36",
                    "url": "https://www.uniprot.org/uniprot/Q8BI36"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Jkamp",
            "url": "https://www.uniprot.org/uniprot/Q8BI36",
            "locus": {
                "chromosome": "12",
                "start_pos": 72148235,
                "end_pos": 72132363,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000005078",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000005078"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000005078",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000005078",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "104771",
            "url": "https://www.ncbi.nlm.nih.gov/gene/104771",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR008485",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008485",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:104771",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:104771",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1915057",
            "url": "http://www.informatics.jax.org/marker/MGI:1915057",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "HWLLHGY",
            "url": "https://omabrowser.org/oma/group/HWLLHGY/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2912838at2759",
            "url": "http://www.orthodb.org/?query=2912838at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12740",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12740",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12740:SF3",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12740:SF3",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12740:SF4",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12740:SF4",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF05571",
            "url": "http://pfam.xfam.org/family/PF05571",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8BI36",
            "url": "http://purl.obolibrary.org/obo/PR_Q8BI36",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001191996",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B8JJ81",
            "url": "https://www.uniprot.org/uniprot/B8JJ81",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B8JJ81-1",
            "url": "https://www.uniprot.org/uniprot/B8JJ81-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BI36",
            "url": "https://www.uniprot.org/uniprot/Q8BI36",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BI36-1",
            "url": "https://www.uniprot.org/uniprot/Q8BI36-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BI36-2",
            "url": "https://www.uniprot.org/uniprot/Q8BI36-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAVDIQPACLGLYCGKTLLFKNGSSEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECTMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRVDRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH",
        "length": 311,
        "header": "sp|Q8BI36-1|JKAMP_MOUSE Isoform 1 of JNK1/MAPK8-associated membrane protein  OS=Mus musculus OX=10090 GN=Jkamp PE=1 SV=2 CANONICAL=Q8BI36-1"
    },
    "isoforms": [
        {
            "isoform_ac": "B8JJ81-1",
            "url": "",
            "sequence": {
                "sequence": "MQAVDIQPACLGLYCGKTLLFKNGSSEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECTMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLL",
                "length": 214,
                "header": "tr|B8JJ81-1|B8JJ81_MOUSE Computationally mapped isoform of JNK1/MAPK8-associated membrane protein  OS=Mus musculus OX=10090 GN=Jkamp PE=4 SV=1 CANONICAL=Q8BI36-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 72141640,
                "end_pos": 72132441,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000125764.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000125764.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000117251.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000117251.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8BI36-1",
            "url": "",
            "sequence": {
                "sequence": "MAVDIQPACLGLYCGKTLLFKNGSSEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECTMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRVDRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH",
                "length": 311,
                "header": "sp|Q8BI36-1|JKAMP_MOUSE Isoform 1 of JNK1/MAPK8-associated membrane protein  OS=Mus musculus OX=10090 GN=Jkamp PE=1 SV=2 CANONICAL=Q8BI36-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 72147599,
                "end_pos": 72132954,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000057257",
                        "url": "https://www.ensembl.org/id/ENSMUST00000057257"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000061370",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000061370"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8BI36-2",
            "url": "",
            "sequence": {
                "sequence": "MACLGLYCGKTLLFKNGSSEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECTMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRVDRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH",
                "length": 305,
                "header": "sp|Q8BI36-2|JKAMP_MOUSE Isoform 2 of JNK1/MAPK8-associated membrane protein  OS=Mus musculus OX=10090 GN=Jkamp PE=1 SV=2 CANONICAL=Q8BI36-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 72147599,
                "end_pos": 72132954,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000117449",
                        "url": "https://www.ensembl.org/id/ENSMUST00000117449"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000113744",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000113744"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "reported",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 22,
            "start_aa": "Asn",
            "end_pos": 22,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn22",
            "evidence": [
                {
                    "id": "Q8BI36",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8BI36#ptm_processing"
                },
                {
                    "id": "16166642",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/16166642"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_reported"
    ],
    "publication": [
        {
            "title": "JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity.",
            "journal": "Molecular and cellular biology",
            "date": "2005",
            "authors": "Kadoya T, Khurana A, Tcherpakov M, Bromberg KD, Didier C, Broday L, Asahara T, Bhoumik A, Ronai Z",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BI36",
                    "url": "https://www.uniprot.org/uniprot/Q8BI36#ptm_processing"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q8BI36",
                    "url": "https://www.uniprot.org/uniprot/Q8BI36"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001191996",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16166642",
                    "url": "https://glygen.org/publication/PubMed/16166642"
                }
            ]
        },
        {
            "title": "JAMP optimizes ERAD to protect cells from unfolded proteins.",
            "journal": "Mol. Biol. Cell",
            "date": "2008",
            "authors": "Tcherpakov M, Broday L, Delaunay A, Kadoya T, Khurana A, Erdjument-Bromage H, Tempst P, Qiu XB, DeMartino GN, Ronai Z",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BI36",
                    "url": "https://www.uniprot.org/uniprot/Q8BI36"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001191996",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18784250",
                    "url": "https://glygen.org/publication/PubMed/18784250"
                }
            ]
        },
        {
            "title": "Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP).",
            "journal": "J. Biol. Chem.",
            "date": "2009",
            "authors": "Tcherpakov M, Delaunay A, Toth J, Kadoya T, Petroski MD, Ronai ZA",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BI36",
                    "url": "https://www.uniprot.org/uniprot/Q8BI36"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19269966",
                    "url": "https://glygen.org/publication/PubMed/19269966"
                }
            ]
        },
        {
            "title": "c-Jun NH2 -Terminal Protein Kinase Phosphorylates the Nrf2-ECH Homology 6 Domain of Nuclear Factor Erythroid 2-Related Factor 2 and Downregulates Cytoprotective Genes in Acetaminophen-Induced Liver Injury in Mice.",
            "journal": "Hepatology (Baltimore, Md.)",
            "date": "2020",
            "authors": "Chen Y, Liu K, Zhang J, Hai Y, Wang P, Wang H, Liu Q, Wong CCL, Yao J, Gao Y, Liao Y, Tang X, Wang XJ",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001191996",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "31945188",
                    "url": "https://glygen.org/publication/PubMed/31945188"
                }
            ]
        },
        {
            "title": "JKAMP inhibits the osteogenic capacity of adipose-derived stem cells in diabetic osteoporosis by modulating the Wnt signaling pathway through intragenic DNA methylation.",
            "journal": "Stem cell research & therapy",
            "date": "2021",
            "authors": "Peng S, Shi S, Tao G, Li Y, Xiao D, Wang L, He Q, Cai X, Xiao J",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001191996",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191996"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "33579371",
                    "url": "https://glygen.org/publication/PubMed/33579371"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:104771",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:104771",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZZT8-1",
            "protein_name": "JNK1/MAPK8-associated membrane protein",
            "gene_name": "Jkamp",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MAVDIQPACLGLYCGKTLLFKNGSSEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECTMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRVDRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH",
                "length": 311
            },
            "evidence": [
                {
                    "id": "45232907",
                    "url": "http://www.informatics.jax.org/homology/45232907",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q9P055-4",
            "protein_name": "JNK1/MAPK8-associated membrane protein",
            "gene_name": "JKAMP",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAVDIQPACLGLYCGKTLLFKNGSTEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECSMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFIYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIISISRVDKLEQDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH",
                "length": 311
            },
            "evidence": [
                {
                    "id": "Q8BI36",
                    "url": "https://omabrowser.org/oma/group/Q8BI36/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BI36",
                                "url": "https://www.uniprot.org/uniprot/Q8BI36"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endoplasmic reticulum membrane",
                        "id": "GO:0005789",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BI36",
                                "url": "https://www.uniprot.org/uniprot/Q8BI36"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "response to unfolded protein",
                        "id": "GO:0006986",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BI36",
                                "url": "https://www.uniprot.org/uniprot/Q8BI36"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin-dependent ERAD pathway",
                        "id": "GO:0030433",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030433",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BI36",
                                "url": "https://www.uniprot.org/uniprot/Q8BI36"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "ubiquitin protein ligase binding",
                        "id": "GO:0031625",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BI36",
                                "url": "https://www.uniprot.org/uniprot/Q8BI36"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 22,
            "end_pos": 24,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "Ubiquitinated by RNF5 via 'Lys-63'-linked ubiquitin linkage in a UBE2N-dependent manner. Ubiquitination decreases association with components of the proteasome and ERAD.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BI36",
                    "url": "https://www.uniprot.org/uniprot/Q8BI36"
                },
                {
                    "database": "PubMed",
                    "id": "19269966",
                    "url": "https://glygen.org/publication/PubMed/19269966"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 1
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "type",
                "subtype",
                "site_category",
                "site_seq",
                "relation",
                "comment",
                "start_pos",
                "start_aa",
                "end_pos",
                "end_aa",
                "residue",
                "site_lbl"
            ]
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 1
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "type",
                "subtype",
                "site_category",
                "site_seq",
                "relation",
                "comment",
                "start_pos",
                "start_aa",
                "end_pos",
                "end_aa",
                "residue",
                "site_lbl"
            ]
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 5
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}
