{
    "uniprot_canonical_ac": "Q8BHD7-1",
    "uniprot_ac": "Q8BHD7",
    "uniprot_id": "PTBP3_MOUSE",
    "mass": {
        "chemical_mass": 56701.0,
        "monoisotopic_mass": 56701.0
    },
    "refseq": {
        "ac": "NP_659153",
        "name": "polypyrimidine tract-binding protein 3 isoform 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_659153"
    },
    "gene_names": [
        {
            "name": "Ptbp3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8BHD7",
            "id": "Q8BHD7"
        },
        {
            "name": "5830471K22Rik; Rod1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_659153",
            "id": "NP_659153"
        },
        {
            "name": "Ptbp3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_659153",
            "id": "NP_659153"
        },
        {
            "name": "Rod1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8BHD7",
            "id": "Q8BHD7"
        }
    ],
    "protein_names": [
        {
            "name": "Polypyrimidine tract-binding protein 3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8BHD7"
        },
        {
            "name": "Regulator of differentiation 1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8BHD7"
        },
        {
            "name": "Rod1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8BHD7"
        },
        {
            "name": "polypyrimidine tract-binding protein 3 isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_659153",
            "id": "NP_659153"
        },
        {
            "name": "regulator of differentiation 1; ROD1 regulator of differentiation 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_659153",
            "id": "NP_659153"
        }
    ],
    "function": [
        {
            "annotation": "Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_659153",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_659153"
                },
                {
                    "database": "PubMed",
                    "id": "34214192",
                    "url": "https://glygen.org/publication/PubMed/34214192"
                }
            ]
        },
        {
            "annotation": "RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes Fas exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U) (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BHD7",
                    "url": "https://www.uniprot.org/uniprot/Q8BHD7#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BHD7",
                    "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Ptbp3",
            "url": "https://www.uniprot.org/uniprot/Q8BHD7",
            "locus": {
                "chromosome": "4",
                "start_pos": 59471868,
                "end_pos": 59549364,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000028382",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000028382"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000028382",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000028382",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd12693",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12693",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd12779",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12779",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "230257",
            "url": "https://www.ncbi.nlm.nih.gov/gene/230257",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000504",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006536",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR012677",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR021790",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR034326",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR034326",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR035979",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:230257",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:230257",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1923334",
            "url": "http://www.informatics.jax.org/marker/MGI:1923334",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "NAHYARM",
            "url": "https://omabrowser.org/oma/group/NAHYARM/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4825346at2759",
            "url": "http://www.orthodb.org/?query=4825346at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR15592",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR15592:SF17",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592:SF17",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00076",
            "url": "http://pfam.xfam.org/family/PF00076",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF11835",
            "url": "http://pfam.xfam.org/family/PF11835",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13893",
            "url": "http://pfam.xfam.org/family/PF13893",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8BHD7",
            "url": "http://purl.obolibrary.org/obo/PR_Q8BHD7",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_659153",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_659153",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F7C521",
            "url": "https://www.uniprot.org/uniprot/F7C521",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F7C521-1",
            "url": "https://www.uniprot.org/uniprot/F7C521-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UXA6",
            "url": "https://www.uniprot.org/uniprot/G3UXA6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UXA6-1",
            "url": "https://www.uniprot.org/uniprot/G3UXA6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UXZ6",
            "url": "https://www.uniprot.org/uniprot/G3UXZ6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UXZ6-1",
            "url": "https://www.uniprot.org/uniprot/G3UXZ6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UXZ8",
            "url": "https://www.uniprot.org/uniprot/G3UXZ8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UXZ8-1",
            "url": "https://www.uniprot.org/uniprot/G3UXZ8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UY95",
            "url": "https://www.uniprot.org/uniprot/G3UY95",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UY95-1",
            "url": "https://www.uniprot.org/uniprot/G3UY95-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UZ01",
            "url": "https://www.uniprot.org/uniprot/G3UZ01",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UZ01-1",
            "url": "https://www.uniprot.org/uniprot/G3UZ01-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UZG7",
            "url": "https://www.uniprot.org/uniprot/G3UZG7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3UZG7-1",
            "url": "https://www.uniprot.org/uniprot/G3UZG7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G8JL74",
            "url": "https://www.uniprot.org/uniprot/G8JL74",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G8JL74-1",
            "url": "https://www.uniprot.org/uniprot/G8JL74-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BHD7",
            "url": "https://www.uniprot.org/uniprot/Q8BHD7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BHD7-1",
            "url": "https://www.uniprot.org/uniprot/Q8BHD7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BHD7-2",
            "url": "https://www.uniprot.org/uniprot/Q8BHD7-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MNSSTSAGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPGALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI",
        "length": 523,
        "header": "sp|Q8BHD7-1|PTBP3_MOUSE Isoform 1 of Polypyrimidine tract-binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 CANONICAL=Q8BHD7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "F7C521-1",
            "url": "",
            "sequence": {
                "sequence": "MSDIVVVTDLIAVGLKRGSDELLSSGVINGPSTMNSSTSAGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQVRNI",
                "length": 104,
                "header": "tr|F7C521-1|F7C521_MOUSE Computationally mapped isoform of Polypyrimidine tract binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59548544,
                "end_pos": 59517574,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000140925.3",
                        "url": "https://www.ensembl.org/id/ENSMUST00000140925.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000122138.3",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000122138.3"
                    }
                ]
            }
        },
        {
            "isoform_ac": "G3UXA6-1",
            "url": "",
            "sequence": {
                "sequence": "MDGVVTDLIAVGLKRGSDELLSSGVINGPSTMNSSTSAGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPGALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI",
                "length": 554,
                "header": "tr|G3UXA6-1|G3UXA6_MOUSE Computationally mapped isoform of Polypyrimidine tract binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59549155,
                "end_pos": 59476886,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000174586.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000174586.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000133612.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000133612.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "G3UXZ6-1",
            "url": "",
            "sequence": {
                "sequence": "MDGVVTDLIAVGLKRGSDELLSSGVINGPSTMNSSTSAGLFRNGF",
                "length": 45,
                "header": "tr|G3UXZ6-1|PTBP3_MOUSE Computationally mapped isoform of Polypyrimidine tract-binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59549155,
                "end_pos": 59514401,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000174748.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000174748.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000133884.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000133884.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "G3UXZ8-1",
            "url": "",
            "sequence": {
                "sequence": "VKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAAVPGALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSP",
                "length": 188,
                "header": "tr|G3UXZ8-1|PTBP3_MOUSE Computationally mapped isoform of Polypyrimidine tract-binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=8 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59493285,
                "end_pos": 59481445,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000172471.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000172471.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000133886.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000133886.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "G3UY95-1",
            "url": "",
            "sequence": {
                "sequence": "MDGVVTDLIAVGLKRAQAALQAVSAVQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLD",
                "length": 146,
                "header": "tr|G3UY95-1|G3UY95_MOUSE Computationally mapped isoform of Polypyrimidine tract binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=8 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59549155,
                "end_pos": 59493241,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000173884.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000173884.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000133996.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000133996.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "G3UZ01-1",
            "url": "",
            "sequence": {
                "sequence": "MAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPGALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI",
                "length": 457,
                "header": "tr|G3UZ01-1|PTBP3_MOUSE Computationally mapped isoform of Polypyrimidine tract-binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59524397,
                "end_pos": 59476886,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000173699.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000173699.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000134290.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000134290.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "G3UZG7-1",
            "url": "",
            "sequence": {
                "sequence": "MDGEPKLHCRLSVQSSQETCPFLELLQMKAHCYLGRALCSG",
                "length": 41,
                "header": "tr|G3UZG7-1|PTBP3_MOUSE Computationally mapped isoform of Polypyrimidine tract-binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59549155,
                "end_pos": 59501360,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000134879.3",
                        "url": "https://www.ensembl.org/id/ENSMUST00000134879.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000134490.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000134490.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "G8JL74-1",
            "url": "",
            "sequence": {
                "sequence": "MDGVVTDLIAVGLKRGSDELLSSGVINGPSTMNSSTSAANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPGALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI",
                "length": 551,
                "header": "tr|G8JL74-1|PTBP3_MOUSE Computationally mapped isoform of Polypyrimidine tract-binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59549155,
                "end_pos": 59476886,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000102883.11",
                        "url": "https://www.ensembl.org/id/ENSMUST00000102883.11"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000099947.5",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000099947.5"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8BHD7-1",
            "url": "",
            "sequence": {
                "sequence": "MNSSTSAGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPGALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI",
                "length": 523,
                "header": "sp|Q8BHD7-1|PTBP3_MOUSE Isoform 1 of Polypyrimidine tract-binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59524425,
                "end_pos": 59476886,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000030076",
                        "url": "https://www.ensembl.org/id/ENSMUST00000030076"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000030076",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000030076"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8BHD7-2",
            "url": "",
            "sequence": {
                "sequence": "MNSSTSAANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPGALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI",
                "length": 520,
                "header": "sp|Q8BHD7-2|PTBP3_MOUSE Isoform 2 of Polypyrimidine tract-binding protein 3  OS=Mus musculus OX=10090 GN=Ptbp3 PE=1 SV=1 CANONICAL=Q8BHD7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 59524425,
                "end_pos": 59476886,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000172768",
                        "url": "https://www.ensembl.org/id/ENSMUST00000172768"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000134102",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000134102"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 109,
            "end_pos": 109,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "Phosphothreonine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BHD7",
                    "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                }
            ],
            "site_lbl": "Thr109"
        },
        {
            "start_pos": 425,
            "end_pos": 425,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BHD7",
                    "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                }
            ],
            "site_lbl": "Ser425"
        },
        {
            "start_pos": 98,
            "end_pos": 98,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BHD7",
                    "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                }
            ],
            "site_lbl": "Tyr98"
        }
    ],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice.",
            "journal": "European journal of immunology",
            "date": "2021",
            "authors": "Monzon-Casanova E, Bates KJ, Smith CWJ, Turner M",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_659153",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_659153"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34214192",
                    "url": "https://glygen.org/publication/PubMed/34214192"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:230257",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:230257",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "O95758-3",
            "protein_name": "Polypyrimidine tract-binding protein 3",
            "gene_name": "PTBP3",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MDGVVTDLITVGLKRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI",
                "length": 552
            },
            "evidence": [
                {
                    "id": "45238459",
                    "url": "http://www.informatics.jax.org/homology/45238459",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Z118-1",
            "protein_name": "Polypyrimidine tract-binding protein 3",
            "gene_name": "Ptbp3",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MNNSTSAGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATSNEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVSAVPGALGPLTLTSSAVSGRMAIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI",
                "length": 523
            },
            "evidence": [
                {
                    "id": "45238459",
                    "url": "http://www.informatics.jax.org/homology/45238459",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "RNA binding",
                        "id": "GO:0003723",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mRNA binding",
                        "id": "GO:0003729",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleic acid binding",
                        "id": "GO:0003676",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "mRNA processing",
                        "id": "GO:0006397",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "erythrocyte maturation",
                        "id": "GO:0043249",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043249",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "RNA splicing",
                        "id": "GO:0008380",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of mRNA splicing, via spliceosome",
                        "id": "GO:0048025",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048025",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of cell differentiation",
                        "id": "GO:0045595",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045595",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of RNA splicing",
                        "id": "GO:0043484",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of RNA splicing",
                        "id": "GO:0033119",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033119",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BHD7",
                                "url": "https://www.uniprot.org/uniprot/Q8BHD7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 132,
            "end_pos": 134,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 2,
            "end_pos": 4,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                    "field": "n_linked_glycan_sites",
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                {
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
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        {
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        {
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            ],
            "sort_fields": []
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        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
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                    "field": "total",
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                {
                    "field": "total_sites",
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                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
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                    "field": "total",
                    "count": 3
                },
                {
                    "field": "total_sites",
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                }
            ],
            "sort_fields": [
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        },
        {
            "table_id": "snv",
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                {
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        {
            "table_id": "snv_disease",
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        {
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    ]
}