{
    "uniprot_canonical_ac": "Q8BFW9-1",
    "uniprot_ac": "Q8BFW9",
    "uniprot_id": "GTR12_MOUSE",
    "mass": {
        "chemical_mass": 67336.0,
        "monoisotopic_mass": 67336.0
    },
    "refseq": {
        "ac": "NP_849265",
        "name": "solute carrier family 2, facilitated glucose transporter member 12",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
    },
    "gene_names": [
        {
            "name": "Slc2a12",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8BFW9",
            "id": "Q8BFW9"
        },
        {
            "name": "GLUT-12; Glut12",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265",
            "id": "NP_849265"
        },
        {
            "name": "Glut12",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8BFW9",
            "id": "Q8BFW9"
        },
        {
            "name": "Slc2a12",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265",
            "id": "NP_849265"
        }
    ],
    "protein_names": [
        {
            "name": "Solute carrier family 2, facilitated glucose transporter member 12",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8BFW9"
        },
        {
            "name": "GLUT-12",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8BFW9"
        },
        {
            "name": "Glucose transporter type 12",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8BFW9"
        },
        {
            "name": "facilitated glucose transporter; glucose transporter type 12; solute carrier family 2, member 12",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265",
            "id": "NP_849265"
        },
        {
            "name": "solute carrier family 2, facilitated glucose transporter member 12",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265",
            "id": "NP_849265"
        }
    ],
    "function": [
        {
            "annotation": "Analysis of Glut12 expression in mouse preimplantation embryos",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                },
                {
                    "database": "PubMed",
                    "id": "15465484",
                    "url": "https://glygen.org/publication/PubMed/15465484"
                }
            ]
        },
        {
            "annotation": "Effect of aging and obesity on GLUT12 expression in small intestine, adipose tissue, muscle, and kidney and its regulation by docosahexaenoic acid and exercise in mice. Erratum:[Appl Physiol Nutr Metab. 2021 Jul;46(7):846-847. PMID: 34185593]",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                },
                {
                    "database": "PubMed",
                    "id": "32176854",
                    "url": "https://glygen.org/publication/PubMed/32176854"
                }
            ]
        },
        {
            "annotation": "Expression in adipose tissue",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                },
                {
                    "database": "PubMed",
                    "id": "12890477",
                    "url": "https://glygen.org/publication/PubMed/12890477"
                }
            ]
        },
        {
            "annotation": "GLUT12 Expression in Brain of Mouse Models of Alzheimer's Disease.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                },
                {
                    "database": "PubMed",
                    "id": "31473905",
                    "url": "https://glygen.org/publication/PubMed/31473905"
                }
            ]
        },
        {
            "annotation": "GLUT8 and GLUT12 exhibit dramatic differences in trafficking from the plasma membrane",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                },
                {
                    "database": "PubMed",
                    "id": "19076329",
                    "url": "https://glygen.org/publication/PubMed/19076329"
                }
            ]
        },
        {
            "annotation": "Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                },
                {
                    "database": "PubMed",
                    "id": "32690690",
                    "url": "https://glygen.org/publication/PubMed/32690690"
                }
            ]
        },
        {
            "annotation": "Insulin-independent facilitative glucose transporter.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BFW9",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9#function"
                },
                {
                    "database": "PubMed",
                    "id": "23041416",
                    "url": "https://glygen.org/publication/PubMed/23041416"
                }
            ]
        },
        {
            "annotation": "XXX amino acids, specifically the position of a proline -2 from the dileucine residues, influence the affinity of APs for GLUT8 and GLUT12",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                },
                {
                    "database": "PubMed",
                    "id": "21067453",
                    "url": "https://glygen.org/publication/PubMed/21067453"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BFW9",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Slc2a12",
            "url": "https://www.uniprot.org/uniprot/Q8BFW9",
            "locus": {
                "chromosome": "10",
                "start_pos": 22580184,
                "end_pos": 22520910,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000037490",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000037490"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000037490",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000037490",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd17435",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17435",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "353169",
            "url": "https://www.ncbi.nlm.nih.gov/gene/353169",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR003663",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003663",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR005828",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR005829",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR020846",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036259",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:353169",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:353169",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "3052471",
            "url": "http://www.informatics.jax.org/marker/MGI:3052471",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "WNCILAF",
            "url": "https://omabrowser.org/oma/group/WNCILAF/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2013244at2759",
            "url": "http://www.orthodb.org/?query=2013244at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR48023",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48023",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR48023:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48023:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00083",
            "url": "http://pfam.xfam.org/family/PF00083",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8BFW9",
            "url": "http://purl.obolibrary.org/obo/PR_Q8BFW9",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-189200",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-189200",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_849265",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "60376",
            "url": "https://www.rhea-db.org/rhea/60376",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "Q8BFW9",
            "url": "https://www.uniprot.org/uniprot/Q8BFW9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8BFW9-1",
            "url": "https://www.uniprot.org/uniprot/Q8BFW9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MVPVENTEGPNLLNQKGREAETEGSCGASGGGHPACAGGPSMFTFLTSVTAAISGLLVGYELGLISGALLQIRTLLALTCHEQEMVVSSLLIGAFLASLTGGVLIDRYGRRLAIILSSCLLGLGSLVLIMSLSYTLLIMGRVAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVTGILFAYISNYAFANISNGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEESAGKVLRKLRVISDTTEELTLIKSSLKDEYQYSFWDLFRSKDNMRTRILIGLTLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVVSTIPATLLVDHIGSKTFLCIGSSVMSASLLTMGIVNLNINMNFTNICRSHSLLNQSLEEFVFYATGNLSISNSSLREHFKRITPYSKGSFMPMGNGMEPKGEMTFTSSLPNAGLSRTEHQGVTDTAVVPAAYKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGVNLLISLTFLTVTDLIGLSWVCFIYTIMSLASLAFVVLFIPETKGCSLEQISVELAKANYVKNNICFMSHHQEELVPTQLQKRKPQEQLPECNHLCGRGQSQRPSPDT",
        "length": 622,
        "header": "sp|Q8BFW9-1|GTR12_MOUSE Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 12  OS=Mus musculus OX=10090 GN=Slc2a12 PE=2 SV=1 CANONICAL=Q8BFW9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q8BFW9-1",
            "url": "",
            "sequence": {
                "sequence": "MVPVENTEGPNLLNQKGREAETEGSCGASGGGHPACAGGPSMFTFLTSVTAAISGLLVGYELGLISGALLQIRTLLALTCHEQEMVVSSLLIGAFLASLTGGVLIDRYGRRLAIILSSCLLGLGSLVLIMSLSYTLLIMGRVAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVTGILFAYISNYAFANISNGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEESAGKVLRKLRVISDTTEELTLIKSSLKDEYQYSFWDLFRSKDNMRTRILIGLTLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVVSTIPATLLVDHIGSKTFLCIGSSVMSASLLTMGIVNLNINMNFTNICRSHSLLNQSLEEFVFYATGNLSISNSSLREHFKRITPYSKGSFMPMGNGMEPKGEMTFTSSLPNAGLSRTEHQGVTDTAVVPAAYKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGVNLLISLTFLTVTDLIGLSWVCFIYTIMSLASLAFVVLFIPETKGCSLEQISVELAKANYVKNNICFMSHHQEELVPTQLQKRKPQEQLPECNHLCGRGQSQRPSPDT",
                "length": 622,
                "header": "sp|Q8BFW9-1|GTR12_MOUSE Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 12  OS=Mus musculus OX=10090 GN=Slc2a12 PE=2 SV=1 CANONICAL=Q8BFW9-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 22578071,
                "end_pos": 22521098,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000042261",
                        "url": "https://www.ensembl.org/id/ENSMUST00000042261"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000043962",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000043962"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 195,
            "start_aa": "Asn",
            "end_pos": 195,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn195",
            "evidence": [
                {
                    "id": "Q8BFW9",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 375,
            "start_aa": "Asn",
            "end_pos": 375,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn375",
            "evidence": [
                {
                    "id": "Q8BFW9",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 387,
            "start_aa": "Asn",
            "end_pos": 387,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn387",
            "evidence": [
                {
                    "id": "Q8BFW9",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 400,
            "start_aa": "Asn",
            "end_pos": 400,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn400",
            "evidence": [
                {
                    "id": "Q8BFW9",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 405,
            "start_aa": "Asn",
            "end_pos": 405,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn405",
            "evidence": [
                {
                    "id": "Q8BFW9",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Expression of class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues.",
            "journal": "Biochem. Biophys. Res. Commun.",
            "date": "2003",
            "authors": "Wood IS, Hunter L, Trayhurn P",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BFW9",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12890477",
                    "url": "https://glygen.org/publication/PubMed/12890477"
                }
            ]
        },
        {
            "title": "Identification of the facilitative glucose transporter 12 gene Glut12 in mouse preimplantation embryos.",
            "journal": "Gene Expr. Patterns",
            "date": "2004",
            "authors": "Zhou Y, Kaye PL, Pantaleon M",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BFW9",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15465484",
                    "url": "https://glygen.org/publication/PubMed/15465484"
                }
            ]
        },
        {
            "title": "Similar [DE]XXXL[LI] motifs differentially target GLUT8 and GLUT12 in Chinese hamster ovary cells.",
            "journal": "Traffic (Copenhagen, Denmark)",
            "date": "2009",
            "authors": "Flessner LB, Moley KH",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19076329",
                    "url": "https://glygen.org/publication/PubMed/19076329"
                }
            ]
        },
        {
            "title": "The amino acids upstream of NH(2)-terminal dileucine motif play a role in regulating the intracellular sorting of the Class III transporters GLUT8 and GLUT12.",
            "journal": "Molecular membrane biology",
            "date": "2011",
            "authors": "Aerni-Flessner LB, Otu MC, Moley KH",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "21067453",
                    "url": "https://glygen.org/publication/PubMed/21067453"
                }
            ]
        },
        {
            "title": "GLUT12 functions as a basal and insulin-independent glucose transporter in the heart.",
            "journal": "Biochim. Biophys. Acta",
            "date": "2013",
            "authors": "Waller AP, George M, Kalyanasundaram A, Kang C, Periasamy M, Hu K, Lacombe VA",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8BFW9",
                    "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "23041416",
                    "url": "https://glygen.org/publication/PubMed/23041416"
                }
            ]
        },
        {
            "title": "GLUT12 Expression in Brain of Mouse Models of Alzheimer's Disease.",
            "journal": "Molecular neurobiology",
            "date": "2020",
            "authors": "Gil-Iturbe E, Solas M, Cuadrado-Tejedo M, Garcia-Osta A, Escote X, Ramirez MJ, Lostao MP",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "31473905",
                    "url": "https://glygen.org/publication/PubMed/31473905"
                }
            ]
        },
        {
            "title": "Effect of aging and obesity on GLUT12 expression in small intestine, adipose tissue, muscle, and kidney and its regulation by docosahexaenoic acid and exercise in mice.",
            "journal": "Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme",
            "date": "2020",
            "authors": "Gil-Iturbe E, Felix-Soriano E, Sainz N, Idoate-Bayon A, Castilla-Madrigal R, Moreno-Aliaga MJ, Lostao MP",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "32176854",
                    "url": "https://glygen.org/publication/PubMed/32176854"
                }
            ]
        },
        {
            "title": "Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice.",
            "journal": "Proceedings of the National Academy of Sciences of the United States of America",
            "date": "2020",
            "authors": "Toyoda Y, Takada T, Miyata H, Matsuo H, Kassai H, Nakao K, Nakatochi M, Kawamura Y, Shimizu S, Shinomiya N, Ichida K, Hosoyamada M, Aiba A, Suzuki H",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_849265",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_849265"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "32690690",
                    "url": "https://glygen.org/publication/PubMed/32690690"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:353169",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:353169",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-189200",
            "name": "Cellular hexose transport",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-189200",
            "resource": "Reactome",
            "description": "Cellular hexose transport"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZNG4-1",
            "protein_name": "Solute carrier family 2 member 12",
            "gene_name": "Slc2a12",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MVPVENTEGPNLLNQKGREAETDGSCGASGGRHPACAGGPGMFTFLTSVTAAISGLLVGYELGLISGALLQIRTLLALTCHEQEMVVSSLLIGAFLASLTGGVLIDRYGRRLTIILSSCLLGLGSLVLILSLSYTLLITGRVAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVTGILFAYISNYAFANISNGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEEAAGKVLRKLRVISDTAEELTLIKSSLKDEYQYSFWDLFRSKDNMRTRILIGLTLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVVSTIPATLLVDHVGSKTFLCIGSSVMAASLLTMGIVNLNINMNFTNICRSHSPLNQSLEELVFYATGNLSVSNSSLGEHLKRVTPYSKGLFIPLGNGMEPKGEMAFTSLPNAGLSRTDRQGVTDPAVVPAVYKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLSWVCFIYTVMSLTSLAFVVLFIPETKGCSLEQISMELSKANYVKNNICFMSHHQEELVPTQLQKTKPQEQLPECKKLCGRGQSQRPSPET",
                "length": 621
            },
            "evidence": [
                {
                    "id": "45237106",
                    "url": "http://www.informatics.jax.org/homology/45237106",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q8TD20-1",
            "protein_name": "Solute carrier family 2, facilitated glucose transporter member 12",
            "gene_name": "SLC2A12",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLECNKLCGRGQSRQLSPET",
                "length": 617
            },
            "evidence": [
                {
                    "id": "45237106",
                    "url": "http://www.informatics.jax.org/homology/45237106",
                    "database": "MGI"
                },
                {
                    "id": "Q8BFW9",
                    "url": "https://omabrowser.org/oma/group/Q8BFW9/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "circulatory system development",
                        "id": "GO:0072359",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072359",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BFW9",
                                "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glucose transmembrane transport",
                        "id": "GO:1904659",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904659",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BFW9",
                                "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BFW9",
                                "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BFW9",
                                "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "perinuclear region of cytoplasm",
                        "id": "GO:0048471",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BFW9",
                                "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endomembrane system",
                        "id": "GO:0012505",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BFW9",
                                "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "symporter activity",
                        "id": "GO:0015293",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BFW9",
                                "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glucose transmembrane transporter activity",
                        "id": "GO:0005355",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005355",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8BFW9",
                                "url": "https://www.uniprot.org/uniprot/Q8BFW9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 195,
            "end_pos": 197,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 375,
            "end_pos": 377,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 387,
            "end_pos": 389,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 400,
            "end_pos": 402,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 405,
            "end_pos": 407,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [
        {
            "id": "60376",
            "name": "",
            "equation": "D-glucose(out) = D-glucose(in)",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [],
            "evidence": [
                {
                    "id": "60376",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/60376"
                }
            ]
        }
    ],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 5
                },
                {
                    "field": "total_sites",
                    "count": 5
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 5
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "type",
                "subtype",
                "site_category",
                "site_seq",
                "relation",
                "comment",
                "start_pos",
                "start_aa",
                "end_pos",
                "end_aa",
                "residue",
                "site_lbl"
            ]
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 5
                },
                {
                    "field": "total_sites",
                    "count": 5
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 5
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "type",
                "subtype",
                "site_category",
                "site_seq",
                "relation",
                "comment",
                "start_pos",
                "start_aa",
                "end_pos",
                "end_aa",
                "residue",
                "site_lbl"
            ]
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 8
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}