{ "uniprot_canonical_ac": "Q80Z08-1", "uniprot_ac": "Q80Z08", "uniprot_id": "Q80Z08_MOUSE", "mass": { "chemical_mass": 96765.0, "monoisotopic_mass": 96765.0 }, "refseq": { "ac": "NP_945199", "name": "vomeronasal 2, receptor 43 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_945199" }, "gene_names": [ { "name": "Vmn2r43", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q80Z08", "id": "Q80Z08" }, { "name": "EC2-V2R; Gm1961", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_945199", "id": "NP_945199" }, { "name": "EC2-V2R", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q80Z08", "id": "Q80Z08" }, { "name": "Gm1961", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q80Z08", "id": "Q80Z08" }, { "name": "Vmn2r43", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_945199", "id": "NP_945199" } ], "protein_names": [ { "name": "EC2-V2R pheromone receptor protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q80Z08" }, { "name": "EC2-V2R pheromone receptor; vomeronasal receptor Vmn2r43", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_945199", "id": "NP_945199" }, { "name": "Vomeronasal 2, receptor 43", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q80Z08" }, { "name": "vomeronasal 2, receptor 43 precursor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_945199", "id": "NP_945199" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80Z08", "url": "https://www.uniprot.org/uniprot/Q80Z08" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Vmn2r43", "url": "https://www.uniprot.org/uniprot/Q80Z08", "locus": { "chromosome": "7", "start_pos": 8247347, "end_pos": 8263598, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000053720", "url": "https://www.ensembl.org/id/ENSMUSG00000053720" } ] } } ], "crossref": [ { "id": "cd06365", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06365", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "381838", "url": "https://www.ncbi.nlm.nih.gov/gene/381838", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:381838", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:381838", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "3037819", "url": "http://www.informatics.jax.org/marker/MGI:3037819", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "FYSTMTS", "url": "https://omabrowser.org/oma/group/FYSTMTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "4332316at2759", "url": "http://www.orthodb.org/?query=4332316at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061:SF436", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061:SF436", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "http://pfam.xfam.org/family/PF00003", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01094", "url": "http://pfam.xfam.org/family/PF01094", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF07562", "url": "http://pfam.xfam.org/family/PF07562", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_945199", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_945199", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q80Z08", "url": "https://www.uniprot.org/uniprot/Q80Z08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q80Z08-1", "url": "https://www.uniprot.org/uniprot/Q80Z08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTLMGVFFFLNIPLFMANFIDPRCFWRINLNEIQDEYLGLTCAFILAAVQKPIEKDYFNKTLNFLKTTKNHKYALALVFSMDEINRNPDLLPNMSLIIRYTLGRCDGKTGIPTPYLLHKKKQSPIPNYFCNEESMCSFLLTGPNWEILQLTYGPFHSTFSDDEQYPYLYQMAPKDTSLALAMVSFIHYFNWNWIGLLIPDDDQGNQFLLELKKQSGNKKICFAFVKMISVDDILLEQKTEMYYQQIVMSSSNVIIIYEETINFIDLIFRMWEPPVLRRIWITTKQWNFPTSKRDITHGTFYGSLTFLPHRGGISGFKNFVQTWFHLRSKDLYLVMPEWKYFKYESLASNCKMLKSNSSNASFDWLMEQKFDMAFSESSHNIYNAVYVVAHALHEMNLQQVDNQAVDNGKGASSHCLKVNSFLRKIHFTNPVGDKVIMKQRVIMQEDYDIFHFENLSQHLGIKVKLGKFSPYFSHGRNFHLYVDMLEVATGSRKMPSSVCSAECSPGFRRLWKEGMAACCFVCRPCPENEISNETNMDQCVNCPEYQYANTEQNKCIKKGVTFLSYEDPLGMVLALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRILSYILLLSLMSCFLCSFFFIGHPNRATCVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRHFLVSGTPNYIIPICSLFQCVLCAIWLAVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFIVAFLAKNLPDTFNEAKFLTFSMLVFFSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNSTQNIKESNSTQKIKEKSNS", "length": 845, "header": "tr|Q80Z08-1|Q80Z08_MOUSE Isoform 1 of Vomeronasal 2, receptor 43 OS=Mus musculus OX=10090 GN=Vmn2r43 PE=2 SV=1 CANONICAL=Q80Z08-1" }, "isoforms": [ { "isoform_ac": "Q80Z08-1", "url": "", "sequence": { "sequence": "MLTLMGVFFFLNIPLFMANFIDPRCFWRINLNEIQDEYLGLTCAFILAAVQKPIEKDYFNKTLNFLKTTKNHKYALALVFSMDEINRNPDLLPNMSLIIRYTLGRCDGKTGIPTPYLLHKKKQSPIPNYFCNEESMCSFLLTGPNWEILQLTYGPFHSTFSDDEQYPYLYQMAPKDTSLALAMVSFIHYFNWNWIGLLIPDDDQGNQFLLELKKQSGNKKICFAFVKMISVDDILLEQKTEMYYQQIVMSSSNVIIIYEETINFIDLIFRMWEPPVLRRIWITTKQWNFPTSKRDITHGTFYGSLTFLPHRGGISGFKNFVQTWFHLRSKDLYLVMPEWKYFKYESLASNCKMLKSNSSNASFDWLMEQKFDMAFSESSHNIYNAVYVVAHALHEMNLQQVDNQAVDNGKGASSHCLKVNSFLRKIHFTNPVGDKVIMKQRVIMQEDYDIFHFENLSQHLGIKVKLGKFSPYFSHGRNFHLYVDMLEVATGSRKMPSSVCSAECSPGFRRLWKEGMAACCFVCRPCPENEISNETNMDQCVNCPEYQYANTEQNKCIKKGVTFLSYEDPLGMVLALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRILSYILLLSLMSCFLCSFFFIGHPNRATCVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRHFLVSGTPNYIIPICSLFQCVLCAIWLAVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFIVAFLAKNLPDTFNEAKFLTFSMLVFFSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNSTQNIKESNSTQKIKEKSNS", "length": 845, "header": "tr|Q80Z08-1|Q80Z08_MOUSE Isoform 1 of Vomeronasal 2, receptor 43 OS=Mus musculus OX=10090 GN=Vmn2r43 PE=2 SV=1 CANONICAL=Q80Z08-1" }, "locus": { "chromosome": "7", "start_pos": 8263564, "end_pos": 8247627, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000066317.5", "url": "https://www.ensembl.org/id/ENSMUST00000066317.5" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000069647.5", "url": "https://www.ensembl.org/id/ENSMUSP00000069647.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Functional expression of murine V2R pheromone receptors involves selective association with the M10 and M1 families of MHC class Ib molecules.", "journal": "Cell", "date": "2003", "authors": "Loconto J, Papes F, Chang E, Stowers L, Jones EP, Takada T, Kumanovics A, Fischer Lindahl K, Dulac C", "evidence": [ { "database": "UniProtKB", "id": "Q80Z08", "url": "https://www.uniprot.org/uniprot/Q80Z08" } ], "reference": [ { "type": "PubMed", "id": "12628182", "url": "https://glygen.org/publication/PubMed/12628182" } ] } ], "pathway": [ { "id": "mmu:381838", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:381838", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AS76-1", "protein_name": "Vomeronasal 2 receptor, 75", "gene_name": "Vom2r75", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLILMVIFFLLNIPFLLANFMDPRCFWKINLNEIKDEVLGMTCSFILETVQKTMDKDYFNQTLNVLNTTTNHKYALALAFTVDEINRNPDLLPNMSLIIKYNLGHCDGKTVTTLSDLFNPNNHLHFPNYLCNEGIMCLVLLTGPHWRASLYLWISVYVYLSPHLFLLFPLDVHVPGFHICSFESEFLQLSYGPFYSIFSDNEQYPYLYQMGPKDSSLALAMVSFIIYFKWNWVGLFISDDDQGNQFLSELKKESQTKDICFAFVNMVSVSDVSYYHKTEMYYNQIVMSSTKVIIIYGETNSIIELSFRMWSSPVKQRIWVTTKQFDCPTSKRDLTHGTFYGTLTFLHHYGEISGFKNFVQTRYNLRSTDLYLVTPEWKYFNYEASASNCKILRNYLSNISLEWLMEQKFDMSFSDYSHNIYNAVYAIAHALHEKNLQEVENQAINNAKGENTHCLKLNSFLRKTHFTNSLGNRVIMKQREVVHGDYNIVHMWNFSQRLGIKVKIGQFSPHFPQGQQLHLYVDMTELATGSRKMPSSVCSADCHPGFRRIWKEEMAVCCFVCNPCPENEISNETNMDQCANCPEYQYANTEKNKCIQKGVIVLSYEDPLGMALALIAFCFSAFTVVVFWVFVKHHDTPIVKANNRILSYLLIVSLMFCFLCSFFFIGYPNRATCILQQITFGIFFTVAISTVLAKTITVVLAFKVTDPGRQLRIFLVSGTPNYIIPICSLLQCILCAIWLAVSPPFVDIDEHSEHGHIIIVCNKGSITAFYCVLGYLACLAFGSFTIAFLAKNLPDTFNEAKFLTFSMLVFCAVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKVYIILMRPDRNSIHKIREKSYF", "length": 874 }, "evidence": [ { "id": "45233671", "url": "http://www.informatics.jax.org/homology/45233671", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZVB5-1", "protein_name": "Vomeronasal 2 receptor, 26", "gene_name": "Vom2r26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFILMEVFFFFLNIPLLMANFIDPKCFWRVNLNEVKDKDLSITCSFILEAVQMPTENDYFNQTLNILKTTKNHKYALALAFSIDEINRNPDLLPNMSLIIKYPLGLCDGQTTLPTPYLFNEIYFRPIPNYFCNEETMCTFLLTGPHWITSYSFWIHLNIFLSPSFLQLTYGPFHSTFSDNEQFPYLYQMNPKDTSLALAMVSFLLYFKWNWVGLVISDDDQGNQFLSELKKESKIKEICFAFVSMLAIDEISFYHKTEMYYNQIVMSSTNVIIIYGKTESIIELSFRMWESPVIQRIWVTTKEMNFPTSKRDLTHDTFYGTLTFLHSHGEISGFKNFVQTWYHLRITDLHLVMPEWKYFNYEASASNCKILKNYSSSASLEWLMEQTFDMVFSDGSRDIYNAVNAMAHALHEMNLHLVDNQAIDNGKGASSHCFKINSFLRKTHFTNPLGDRVIMKEREILQEDYNIFHTWNFSQHIGFKVKIGKFSPYFPHGRHFHLYVDMIELATGSRKMPSSVCTEDCSPGYRRFWKEGMAACCFVCSPCPENAISNETNMDQCVNCPEYQYANTKRDKCIQKNVMFLSYKDPLGMTLAFIAFFFSALTAVVLRVFVKHHDTPIVKANNRILSYLLITSLLFCFLCSFFFIGHPNRATCILQQITFGIVFTVAISTILAKTITVVLAFKVTNPGRRLRNFLVLGTLNYIIPICSLFQCILCAIWLAVSPPFVDTDEHTEYGHIIIVCNKGSVTAFYCVLGYLACLALASFTVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKIMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNAIQKIREKSYF", "length": 853 }, "evidence": [ { "id": "45233671", "url": "http://www.informatics.jax.org/homology/45233671", "database": "MGI" } ], "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "Q80Z08", "url": "https://www.uniprot.org/uniprot/Q80Z08" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q80Z08", "url": "https://www.uniprot.org/uniprot/Q80Z08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 825, "end_pos": 827, "annotation": "n_glycosylation_sequon" }, { "start_pos": 834, "end_pos": 836, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }