{ "uniprot_canonical_ac": "Q7TRX9-1", "uniprot_ac": "Q7TRX9", "uniprot_id": "Q7TRX9_MOUSE", "mass": { "chemical_mass": 35320.0, "monoisotopic_mass": 35320.0 }, "refseq": { "ac": "NP_667134", "name": "olfactory receptor 20", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_667134" }, "gene_names": [ { "name": "Or1e1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q7TRX9", "id": "Q7TRX9" }, { "name": "MOR135-11; MTPCR06; MTPCR55; Olfr20; Olfr21", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_667134", "id": "NP_667134" }, { "name": "Olfr20", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q7TRX9", "id": "Q7TRX9" }, { "name": "Olfr397", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q7TRX9", "id": "Q7TRX9" }, { "name": "Or1e1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_667134", "id": "NP_667134" } ], "protein_names": [ { "name": "Olfactory receptor", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q7TRX9" }, { "name": "olfactory receptor 20", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_667134", "id": "NP_667134" }, { "name": "olfactory receptor 21; GA_x6K02T2P1NL-3514066-3515010", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_667134", "id": "NP_667134" } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_667134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_667134" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q7TRX9", "url": "https://www.uniprot.org/uniprot/Q7TRX9" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Or1e1", "url": "https://www.uniprot.org/uniprot/Q7TRX9", "locus": { "chromosome": "11", "start_pos": 73246777, "end_pos": 73241609, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000062128", "url": "https://www.ensembl.org/id/ENSMUSG00000062128" } ] } } ], "crossref": [ { "id": "ENSMUSG00000062128", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000062128", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "258925", "url": "https://www.ncbi.nlm.nih.gov/gene/258925", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:258925", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:258925", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "109315", "url": "http://www.informatics.jax.org/marker/MGI:109315", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "ARIMFSI", "url": "https://omabrowser.org/oma/group/ARIMFSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5401587at2759", "url": "http://www.orthodb.org/?query=5401587at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "http://pfam.xfam.org/family/PF13853", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-381753", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-381753", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_667134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_667134", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q7TRX9", "url": "https://www.uniprot.org/uniprot/Q7TRX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7TRX9-1", "url": "https://www.uniprot.org/uniprot/Q7TRX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGNQTVIFQFLLLGLPIPTEHQQLYYALFLLMYLTTVLGNLIIIILIRLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDSSITYAGCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFPLHYMSIMSPSLCVSLVLLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFVTGGLILVIPFVLILVSYAQIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTIIGLYLCPSADNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKGALARVICKKKVFFCL", "length": 314, "header": "tr|Q7TRX9-1|Q7TRX9_MOUSE Isoform 1 of Olfactory receptor OS=Mus musculus OX=10090 GN=Or1e1 PE=2 SV=1 CANONICAL=Q7TRX9-1" }, "isoforms": [ { "isoform_ac": "Q7TRX9-1", "url": "", "sequence": { "sequence": "MAEGNQTVIFQFLLLGLPIPTEHQQLYYALFLLMYLTTVLGNLIIIILIRLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDSSITYAGCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFPLHYMSIMSPSLCVSLVLLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFVTGGLILVIPFVLILVSYAQIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTIIGLYLCPSADNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKGALARVICKKKVFFCL", "length": 314, "header": "tr|Q7TRX9-1|Q7TRX9_MOUSE Isoform 1 of Olfactory receptor OS=Mus musculus OX=10090 GN=Or1e1 PE=2 SV=1 CANONICAL=Q7TRX9-1" }, "locus": { "chromosome": "11", "start_pos": 73245522, "end_pos": 73244581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000108465.4", "url": "https://www.ensembl.org/id/ENSMUST00000108465.4" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000104105.3", "url": "https://www.ensembl.org/id/ENSMUSP00000104105.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "mmu:258925", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:258925", "resource": "KEGG Pathway" }, { "id": "R-MMU-381753", "name": "Olfactory Signaling Pathway", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-381753", "resource": "Reactome", "description": "Olfactory Signaling Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5XVL2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGTTERNQTAVSQFLLLGLPIPMEHHLLFYALFLAMYLTTVLGNLLIISIIHLDSHLHTPMYSFLSNLSFSDLCFSSVTMPKLLQSMQSQVPSIPYAGCLAQMYFFLFFADLESFLLVAMAYDRYVAICFPLHYMSIMSPKLCVSLVVLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFVMGGIILVIPFVLIIVSYVRIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSANNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDIKGALIRVLCKKKILFCL", "length": 317 }, "evidence": [ { "id": "45224446", "url": "http://www.informatics.jax.org/homology/45224446", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "P23274-1", "protein_name": "Olfactory receptor 1468", "gene_name": "Olr1468", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEENQTVISQFLLLGLPIPSEHQHVFYALFLSMYLTTVLGNLIIIILIHLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVPSIPFAGCLTQLYFYLYFADLESFLLVAMAYDRYVAICFPLHYMSIMSPKLCVSLVVLSWVLTTFHAMLHTLLMARLSFCADNMIPHFFCDISPLLKLSCSDTHVNELVIFVMGGLVIVIPFVLIIVSYARVVASILKVPSVRGIHKIFSTCGSHLSVVSLFYGTIIGLYLCPSANNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKEALIRVLCKKKITFCL", "length": 314 }, "evidence": [ { "id": "45224446", "url": "http://www.informatics.jax.org/homology/45224446", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "P30953-1", "protein_name": "Olfactory receptor 1E1", "gene_name": "OR1E1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGQNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQNQDPSIPYADCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFPLHYTAIMSPMLCLALVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLAFSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSILKVPSSKGICKAFSTCGSHLSVVSLFYGTVIGLYLCSSANSSTLKDTVMAMMYTVVTPMLNPFIYSLRNRDMKGALSRVIHQKKTFFSL", "length": 314 }, "evidence": [ { "id": "45224446", "url": "http://www.informatics.jax.org/homology/45224446", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "P47887-1", "protein_name": "Olfactory receptor 1E2", "gene_name": "OR1E2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGQNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSILKVPSSKGICKAFSTCGSHLSVVSLFYGTVIGLYLCPSANSSTLKDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL", "length": 323 }, "evidence": [ { "id": "45224446", "url": "http://www.informatics.jax.org/homology/45224446", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "Q7TRX9", "url": "https://www.uniprot.org/uniprot/Q7TRX9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "Q7TRX9", "url": "https://www.uniprot.org/uniprot/Q7TRX9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7TRX9", "url": "https://www.uniprot.org/uniprot/Q7TRX9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q7TRX9", "url": "https://www.uniprot.org/uniprot/Q7TRX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q7TRX9", "url": "https://www.uniprot.org/uniprot/Q7TRX9" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q7TRX9", "url": "https://www.uniprot.org/uniprot/Q7TRX9" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "Q7TRX9", "url": "https://www.uniprot.org/uniprot/Q7TRX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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