{
    "uniprot_canonical_ac": "Q7TQH7-1",
    "uniprot_ac": "Q7TQH7",
    "uniprot_id": "LRP10_MOUSE",
    "mass": {
        "chemical_mass": 76461.0,
        "monoisotopic_mass": 76461.0
    },
    "refseq": {
        "ac": "NP_075369",
        "name": "low-density lipoprotein receptor-related protein 10 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369"
    },
    "gene_names": [
        {
            "name": "Lrp10",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q7TQH7",
            "id": "Q7TQH7"
        },
        {
            "name": "Lrp10",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369",
            "id": "NP_075369"
        },
        {
            "name": "Lrp9",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369",
            "id": "NP_075369"
        },
        {
            "name": "Lrp9",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q7TQH7",
            "id": "Q7TQH7"
        }
    ],
    "protein_names": [
        {
            "name": "Low-density lipoprotein receptor-related protein 10",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q7TQH7"
        },
        {
            "name": "LRP-10",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369",
            "id": "NP_075369"
        },
        {
            "name": "LRP-10",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q7TQH7"
        },
        {
            "name": "low-density lipoprotein receptor-related protein 10 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369",
            "id": "NP_075369"
        }
    ],
    "function": [
        {
            "annotation": "Data show that Calnuc is involved in LRP9 endosomal sorting to prevent the delivery of LRP9 to lysosomes.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_075369",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369"
                },
                {
                    "database": "PubMed",
                    "id": "19497050",
                    "url": "https://glygen.org/publication/PubMed/19497050"
                }
            ]
        },
        {
            "annotation": "Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7TQH7",
                    "url": "https://www.uniprot.org/uniprot/Q7TQH7#function"
                },
                {
                    "database": "PubMed",
                    "id": "11123907",
                    "url": "https://glygen.org/publication/PubMed/11123907"
                }
            ]
        },
        {
            "annotation": "These results suggest that LRP9 cycles between the trans-Golgi network, endosomes and the plasma membrane through a GGA dependent-trafficking mechanism.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_075369",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369"
                },
                {
                    "database": "PubMed",
                    "id": "18461348",
                    "url": "https://glygen.org/publication/PubMed/18461348"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [
        {
            "evidence": [
                {
                    "id": "rs3389309924",
                    "database": "dbSNP",
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389309924"
                }
            ],
            "glycoeffect": [
                "n-glyco-sequon-gain"
            ],
            "start_pos": 168,
            "end_pos": 168,
            "sequence_org": "D",
            "sequence_mut": "N",
            "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (DGS->NGS).",
            "chr_id": "14",
            "chr_pos": "54705313",
            "ref_nt": "A",
            "alt_nt": "null",
            "minor_allelic_frequency": "",
            "site_lbl": "D168",
            "keywords": [
                "ebi",
                "germline"
            ]
        }
    ],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7TQH7",
                    "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Lrp10",
            "url": "https://www.uniprot.org/uniprot/Q7TQH7",
            "locus": {
                "chromosome": "14",
                "start_pos": 54708954,
                "end_pos": 54701594,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000022175",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000022175"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000022175",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000022175",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00041",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd00112",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "65107",
            "url": "https://www.ncbi.nlm.nih.gov/gene/65107",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "GPDB0006005",
            "url": "https://acgg.asia/db/gpdb/symbol/GPDB0006005",
            "database": "GlycoProtDB",
            "categories": [
                "Glycoproteomics"
            ]
        },
        {
            "id": "IPR000859",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR002172",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR023415",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR035914",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036055",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:65107",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:65107",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1929480",
            "url": "http://www.informatics.jax.org/marker/MGI:1929480",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "GRAPMGQ",
            "url": "https://omabrowser.org/oma/group/GRAPMGQ/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2916406at2759",
            "url": "http://www.orthodb.org/?query=2916406at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24270",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24270",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24270:SF17",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24270:SF17",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00057",
            "url": "http://pfam.xfam.org/family/PF00057",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00431",
            "url": "http://pfam.xfam.org/family/PF00431",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q7TQH7",
            "url": "http://purl.obolibrary.org/obo/PR_Q7TQH7",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-975634",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-975634",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_075369",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A2I3BQ24",
            "url": "https://www.uniprot.org/uniprot/A0A2I3BQ24",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A2I3BQ24-1",
            "url": "https://www.uniprot.org/uniprot/A0A2I3BQ24-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A2I3BRF1",
            "url": "https://www.uniprot.org/uniprot/A0A2I3BRF1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A2I3BRF1-1",
            "url": "https://www.uniprot.org/uniprot/A0A2I3BRF1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7TQH7",
            "url": "https://www.uniprot.org/uniprot/Q7TQH7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7TQH7-1",
            "url": "https://www.uniprot.org/uniprot/Q7TQH7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MLSALPLLFLLLGGALARPDRITFPRSACEAPPAVLSEVQGTLQRPLGRDSRSSPANCTWVILGSKDQTVTVRFQKLHLACGSEHLILHSPLQPPISLCEAPSGPLQLPGGNVTITYSYAGARAPMGQGFLLTYSQDWLLCLQEEFQCLNHRCIPAAQRCDGIDACGDGSDEAGCSSDPFPNLNPAPAPTLACNLTLEDFYGVFSSPGYSHLASVSHPQSCLWLLDPHDGRRLAVRFTALDLSYGDAVHVYDGAGPPETPRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSSGRGFNATYHVRGYCLPWDRPCGLGSGLGASENLGERCYSEAQRCDGSWDCADGTDEEGCPGCPPGHFPCGAAGTPGATACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCTDGSDEWDCSYALPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGTSGGRRRQRGRSIRRLVRRLRRWGLLPRTNTPARAPETRSQVTPSVPSEALDDSTGQACEGGAVGGQDGEQAPPLPIKTPIPTPSTLPALATVSEPPGPLPSVPVESSLLSGVVQVLRGRLLPSLWSPGPTWTQTGTHTTVLSPEDEDDVLLLPLAEPEVWVVEAEDEPLLA",
        "length": 713,
        "header": "sp|Q7TQH7-1|LRP10_MOUSE Isoform 1 of Low-density lipoprotein receptor-related protein 10  OS=Mus musculus OX=10090 GN=Lrp10 PE=2 SV=2 CANONICAL=Q7TQH7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A2I3BQ24-1",
            "url": "",
            "sequence": {
                "sequence": "XPLQLPGGNVTITYSYAGARAPMGQGFLLTYSQDWLLCLQEEFQCLNHRCIPAAQRCDGIDACGDGSDEAASLPRSPGWRLRLCSNRHPLPMGSSLPRVPSRLWKTSPQRTLTITLCWETYVLCFRSYARI",
                "length": 131,
                "header": "tr|A0A2I3BQ24-1|A0A2I3BQ24_MOUSE Computationally mapped isoform of Low-density lipoprotein receptor-related protein 10  OS=Mus musculus OX=10090 GN=Lrp10 PE=4 SV=1 CANONICAL=Q7TQH7-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 54706775,
                "end_pos": 54705010,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000228407.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000228407.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000154017.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000154017.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A2I3BRF1-1",
            "url": "",
            "sequence": {
                "sequence": "RDSRSSPANCTWVILGSKDQTVTVR",
                "length": 25,
                "header": "tr|A0A2I3BRF1-1|A0A2I3BRF1_MOUSE Computationally mapped isoform of Low-density lipoprotein receptor-related protein 10  OS=Mus musculus OX=10090 GN=Lrp10 PE=4 SV=1 CANONICAL=Q7TQH7-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 54703167,
                "end_pos": 54703093,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000227760.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000227760.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000154451.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000154451.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q7TQH7-1",
            "url": "",
            "sequence": {
                "sequence": "MLSALPLLFLLLGGALARPDRITFPRSACEAPPAVLSEVQGTLQRPLGRDSRSSPANCTWVILGSKDQTVTVRFQKLHLACGSEHLILHSPLQPPISLCEAPSGPLQLPGGNVTITYSYAGARAPMGQGFLLTYSQDWLLCLQEEFQCLNHRCIPAAQRCDGIDACGDGSDEAGCSSDPFPNLNPAPAPTLACNLTLEDFYGVFSSPGYSHLASVSHPQSCLWLLDPHDGRRLAVRFTALDLSYGDAVHVYDGAGPPETPRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSSGRGFNATYHVRGYCLPWDRPCGLGSGLGASENLGERCYSEAQRCDGSWDCADGTDEEGCPGCPPGHFPCGAAGTPGATACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCTDGSDEWDCSYALPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGTSGGRRRQRGRSIRRLVRRLRRWGLLPRTNTPARAPETRSQVTPSVPSEALDDSTGQACEGGAVGGQDGEQAPPLPIKTPIPTPSTLPALATVSEPPGPLPSVPVESSLLSGVVQVLRGRLLPSLWSPGPTWTQTGTHTTVLSPEDEDDVLLLPLAEPEVWVVEAEDEPLLA",
                "length": 713,
                "header": "sp|Q7TQH7-1|LRP10_MOUSE Isoform 1 of Low-density lipoprotein receptor-related protein 10  OS=Mus musculus OX=10090 GN=Lrp10 PE=2 SV=2 CANONICAL=Q7TQH7-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 54707303,
                "end_pos": 54702032,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000022782",
                        "url": "https://www.ensembl.org/id/ENSMUST00000022782"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000022782",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000022782"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 112,
            "start_aa": "Asn",
            "end_pos": 112,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn112",
            "evidence": [
                {
                    "id": "Q7TQH7",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q7TQH7#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 194,
            "start_aa": "Asn",
            "end_pos": 194,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn194",
            "evidence": [
                {
                    "id": "Q7TQH7",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q7TQH7#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 300,
            "start_aa": "Asn",
            "end_pos": 300,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn300",
            "evidence": [
                {
                    "id": "Q7TQH7",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q7TQH7#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 57,
            "start_aa": "Asn",
            "end_pos": 57,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn57",
            "evidence": [
                {
                    "id": "Q7TQH7",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q7TQH7#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 596,
            "end_pos": 596,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "Phosphothreonine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7TQH7",
                    "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                }
            ],
            "site_lbl": "Thr596"
        }
    ],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "A novel low-density lipoprotein receptor-related protein mediating cellular uptake of apolipoprotein E-enriched beta-VLDL in vitro.",
            "journal": "Biochemistry",
            "date": "2000",
            "authors": "Kojima T., Sugiyama A., Sugiyama T., Yasuda K., Kodama T., Tamura S., Kadowaki T., Yokoi N., Kitamura T., Kimura S., Wada Y., Nosaka T., Kumagai H., Morikawa Y., Senba E.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7TQH7",
                    "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11123907",
                    "url": "https://glygen.org/publication/PubMed/11123907"
                }
            ]
        },
        {
            "title": "Intracellular trafficking of LRP9 is dependent on two acidic cluster/dileucine motifs.",
            "journal": "Histochemistry and cell biology",
            "date": "2008",
            "authors": "Boucher R, Larkin H, Brodeur J, Gagnon H, Theriault C, Lavoie C",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_075369",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18461348",
                    "url": "https://glygen.org/publication/PubMed/18461348"
                }
            ]
        },
        {
            "title": "Calnuc binds to LRP9 and affects its endosomal sorting.",
            "journal": "Traffic (Copenhagen, Denmark)",
            "date": "2009",
            "authors": "Brodeur J, Larkin H, Boucher R, Theriault C, St-Louis SC, Gagnon H, Lavoie C",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_075369",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_075369"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19497050",
                    "url": "https://glygen.org/publication/PubMed/19497050"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:65107",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:65107",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-975634",
            "name": "Retinoid metabolism and transport",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-975634",
            "resource": "Reactome",
            "description": "Retinoid metabolism and transport"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "F7F3K1-1",
            "protein_name": "LDL receptor related protein 10",
            "gene_name": "Lrp10",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MLSALPFLLLLLLGGALARPDRIPFLNSACEAPPAVLLEVQGTLQRPLGRDSRSSPANCTWVILGSKEQTVTVRFQKLHLACGSEHLILHSPLQPPVSLCEAPAGPLQLPGGNVTITYSYAGARAPMGQGFLLTYSQDWLLCLQEEFQCLNHRCIPAAQRCDGIDACGDGSDEAGCRSDPFPNPVPAPTPPCNLTLEDFYGVFSSPGYSHLASVSHPQSCLWLLDPHDGRRLAVRFTALDLSYGDAVHVYDGAGPPETPRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSNGRGFNATYHVRGYCLPWDRPCGLGSGLGASENLGERCYSEAQRCDGSWDCADGTDEEGCPGCPPGHYPCGAAGTPGATACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCTDGSDEWDCSYALPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGTSGGRRRQRGRSVRRLVRRLRRWGLLPRTNTPARAPETRSQATPSVPSEALDDSTGQACEGGAVGGQDGEQAPPLPIKSPIPTPSTLPALATASEPPGPLPSVPVESSLLSGVVQVLRGRLLPSLWPPGPTWTPTGTHTAVLPLEDEDDVLLMPLAEPEVWVVEAEDEPLLA",
                "length": 712
            },
            "evidence": [
                {
                    "id": "45238061",
                    "url": "http://www.informatics.jax.org/homology/45238061",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q7Z4F1-1",
            "protein_name": "Low-density lipoprotein receptor-related protein 10",
            "gene_name": "LRP10",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MLLATLLLLLLGGALAHPDRIIFPNHACEDPPAVLLEVQGTLQRPLVRDSRTSPANCTWLILGSKEQTVTIRFQKLHLACGSERLTLRSPLQPLISLCEAPPSPLQLPGGNVTITYSYAGARAPMGQGFLLSYSQDWLMCLQEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCSSDPFPGLTPRPVPSLPCNVTLEDFYGVFSSPGYTHLASVSHPQSCHWLLDPHDGRRLAVRFTALDLGFGDAVHVYDGPGPPESSRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSNGRGFNATYHVRGYCLPWDRPCGLGSGLGAGEGLGERCYSEAQRCDGSWDCADGTDEEDCPGCPPGHFPCGAAGTSGATACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDCSYVLPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGGPGARRRQRGRLMRRLVRRLRRWGLLPRTNTPARASEARSQVTPSAAPLEALDGGTGPAREGGAVGGQDGEQAPPLPIKAPLPSASTSPAPTTVPEAPGPLPSLPLEPSLLSGVVQALRGRLLPSLGPPGPTRSPPGPHTAVLALEDEDDVLLVPLAEPGVWVAEAEDEPLLT",
                "length": 713
            },
            "evidence": [
                {
                    "id": "45238061",
                    "url": "http://www.informatics.jax.org/homology/45238061",
                    "database": "MGI"
                },
                {
                    "id": "Q7TQH7",
                    "url": "https://omabrowser.org/oma/group/Q7TQH7/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TQH7",
                                "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "clathrin-coated pit",
                        "id": "GO:0005905",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TQH7",
                                "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TQH7",
                                "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "lipid metabolic process",
                        "id": "GO:0006629",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TQH7",
                                "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lipid transport",
                        "id": "GO:0006869",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TQH7",
                                "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "inner ear development",
                        "id": "GO:0048839",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048839",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TQH7",
                                "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "low-density lipoprotein particle receptor activity",
                        "id": "GO:0005041",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005041",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TQH7",
                                "url": "https://www.uniprot.org/uniprot/Q7TQH7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 112,
            "end_pos": 114,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 194,
            "end_pos": 196,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 300,
            "end_pos": 302,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 57,
            "end_pos": 59,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 4
                },
                {
                    "field": "total_sites",
                    "count": 4
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 4
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
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        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
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                    "field": "total",
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                {
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                {
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                {
                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
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                    "field": "total",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
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                {
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                {
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                {
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        },
        {
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                    "field": "total",
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                {
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            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
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        },
        {
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            ],
            "sort_fields": [
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        },
        {
            "table_id": "snv_disease",
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        {
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        {
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        }
    ]
}
