{
    "uniprot_canonical_ac": "Q7TNB2-1",
    "uniprot_ac": "Q7TNB2",
    "uniprot_id": "TNNT1_RAT",
    "mass": {
        "chemical_mass": 31215.0,
        "monoisotopic_mass": 31215.0
    },
    "refseq": {
        "ac": "NP_001264189",
        "name": "troponin T, slow skeletal muscle isoform 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264189"
    },
    "gene_names": [
        {
            "name": "Tnnt1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q7TNB2",
            "id": "Q7TNB2"
        },
        {
            "name": "Fang2; sTnT; tnTs",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264189",
            "id": "NP_001264189"
        },
        {
            "name": "Fang2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q7TNB2",
            "id": "Q7TNB2"
        },
        {
            "name": "Tnnt1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264189",
            "id": "NP_001264189"
        }
    ],
    "protein_names": [
        {
            "name": "Troponin T, slow skeletal muscle",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q7TNB2"
        },
        {
            "name": "Slow skeletal muscle troponin T",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q7TNB2"
        },
        {
            "name": "TnTs",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q7TNB2"
        },
        {
            "name": "sTnT",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q7TNB2"
        },
        {
            "name": "troponin T, slow skeletal muscle isoform 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264189",
            "id": "NP_001264189"
        },
        {
            "name": "troponin T, slow skeletal muscle; slow skeletal muscle troponin T; troponin T1, skeletal, slow; troponin T type 1 (skeletal, slow)",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264189",
            "id": "NP_001264189"
        }
    ],
    "function": [
        {
            "annotation": "Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8I5YBH8",
                    "url": "https://www.uniprot.org/uniprot/A0A8I5YBH8#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "ARBA00003363",
                    "url": "https://www.uniprot.org/uniprot/ARBA00003363#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q7TNB2",
                    "url": "https://www.uniprot.org/uniprot/Q7TNB2#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050700",
            "recommended_name": {
                "id": "DOID:0050700",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050700",
                "name": "cardiomyopathy",
                "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle."
            },
            "synonyms": [
                {
                    "id": "DOID:0050700",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050700",
                    "name": "Cardiomyopathies",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0050700",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050700"
                }
            ]
        },
        {
            "disease_id": "DOID:0060036",
            "recommended_name": {
                "id": "DOID:0060036",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060036",
                "name": "intrinsic cardiomyopathy",
                "description": "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0060036",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060036"
                }
            ]
        },
        {
            "disease_id": "DOID:0081374",
            "recommended_name": {
                "id": "DOID:0081374",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0081374",
                "name": "nemaline myopathy 5B",
                "description": "A nemaline myopathy that has_material_basis_in autosomal recessive inheritance of a homozygous or compound heterozygous mutation in the TNNT1 gene on chromosome 19q13, with childhood onset."
            },
            "synonyms": [
                {
                    "id": "MONDO:0957281",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0957281",
                    "name": "nemaline myopathy 5B, autosomal recessive, childhood-onset",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0081374",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081374"
                }
            ]
        },
        {
            "disease_id": "DOID:0081375",
            "recommended_name": {
                "id": "DOID:0081375",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0081375",
                "name": "nemaline myopathy 5C",
                "description": "A nemaline myopathy that has_material_basis_in autosomal dominant inheritance of a homozygous or compound heterozygous mutation in the TNNT1 gene on chromosome 19q13."
            },
            "synonyms": [
                {
                    "id": "MONDO:0957284",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0957284",
                    "name": "nemaline myopathy 5C, autosomal dominant",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0081375",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081375"
                }
            ]
        },
        {
            "disease_id": "DOID:0110936",
            "recommended_name": {
                "id": "DOID:0110936",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0110936",
                "name": "nemaline myopathy 5A",
                "description": "A nemaline myopathy that has_material_basis_in autosomal recessive inheritance of a homozygous mutation in the TNNT1 gene on chromosome 19q13, with infantile onset."
            },
            "synonyms": [
                {
                    "id": "DOID:0110936",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110936",
                    "name": "ANM",
                    "description": ""
                },
                {
                    "id": "DOID:0110936",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110936",
                    "name": "Amish nemaline myopathy",
                    "description": ""
                },
                {
                    "id": "DOID:0110936",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110936",
                    "name": "NEM5",
                    "description": ""
                },
                {
                    "id": "DOID:0110936",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110936",
                    "name": "nemaline myopathy 5, Amish type",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "nemaline myopathy 5",
                    "description": "Amish nemaline myopathy is a type of nemaline myopathy (NM) only observed in several families of the Amish community."
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "ANM",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "Amish nemaline myopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "NEM5",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "TNNT1 nemaline myopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "nemaline myopathy 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "nemaline myopathy 5, Amish type",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "nemaline myopathy caused by mutation in TNNT1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "nemaline myopathy type 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "nemaline myopathy, Amish type",
                    "description": ""
                },
                {
                    "id": "MONDO:0011539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011539",
                    "name": "nemaline myopathy, caused by mutation in the troponin t1 gene",
                    "description": ""
                },
                {
                    "id": "MIM:605355",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/605355",
                    "name": "Nemaline myopathy 5",
                    "description": "Nemaline myopathy 5"
                }
            ],
            "evidence": [
                {
                    "id": "0110936",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110936"
                }
            ]
        },
        {
            "disease_id": "DOID:3191",
            "recommended_name": {
                "id": "DOID:3191",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3191",
                "name": "nemaline myopathy",
                "description": "A congenital myopathy characterized by generally non-progressive muscle weakness of varying severity and problems with the tone and contraction of skeletal muscles. The muscle cells contain abnormal clumps of threadlike material called nemaline bodies."
            },
            "synonyms": [
                {
                    "id": "DOID:3191",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3191",
                    "name": "Nemaline body disease",
                    "description": ""
                },
                {
                    "id": "DOID:3191",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3191",
                    "name": "nemaline rod myopathy",
                    "description": ""
                },
                {
                    "id": "DOID:3191",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3191",
                    "name": "rod myopathy",
                    "description": ""
                },
                {
                    "id": "DOID:3191",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3191",
                    "name": "rod body disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "nemaline myopathy 3",
                    "description": "An inherited myopathy caused by mutations in the ACTA1 gene, encoding actin, alpha skeletal muscle. The phenotype is highly variable, and as such attempts at classification by clinical features is not optimal. Generally, affected individuals have generalized muscle weakness, typically involving proximal muscles, the face, bulbar and respiratory muscles."
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "ACTA1 nemaline myopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "NEM3",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "actin myopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "congenital myopathy with excess of thin filaments",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "nemaline myopathy 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "nemaline myopathy 3, autosomal dominant or recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "nemaline myopathy caused by mutation in ACTA1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "nemaline myopathy type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "myopathy, actin, congenital, with Excess of thin myofilaments",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "myopathy, actin, congenital, with cores",
                    "description": ""
                },
                {
                    "id": "MONDO:0008070",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008070",
                    "name": "nemaline myopathy 3, with intranuclear rods",
                    "description": ""
                },
                {
                    "id": "MIM:161800",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/161800",
                    "name": "Congenital myopathy 2A, typical, autosomal dominant",
                    "description": "Congenital myopathy 2A, typical, autosomal dominant"
                }
            ],
            "evidence": [
                {
                    "id": "3191",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3191"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7TNB2",
                    "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Tnnt1",
            "url": "https://www.uniprot.org/uniprot/Q7TNB2",
            "locus": {
                "chromosome": "1",
                "start_pos": 69316721,
                "end_pos": 69306362,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000028041",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000028041"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000028041",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000028041",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "171409",
            "url": "https://www.ncbi.nlm.nih.gov/gene/171409",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001978",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001978",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR027707",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027707",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR038077",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038077",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:171409",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:171409",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "EWIYELE",
            "url": "https://omabrowser.org/oma/group/EWIYELE/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5362548at2759",
            "url": "http://www.orthodb.org/?query=5362548at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11521",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11521",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11521:SF6",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11521:SF6",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00992",
            "url": "http://pfam.xfam.org/family/PF00992",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q7TNB2",
            "url": "http://purl.obolibrary.org/obo/PR_Q7TNB2",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-RNO-390522",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-390522",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001264189",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264189",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "621852",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=621852",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8I5YBH8",
            "url": "https://www.uniprot.org/uniprot/A0A8I5YBH8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5YBH8-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5YBH8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7TNB2",
            "url": "https://www.uniprot.org/uniprot/Q7TNB2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7TNB2-1",
            "url": "https://www.uniprot.org/uniprot/Q7TNB2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7TNB2-2",
            "url": "https://www.uniprot.org/uniprot/Q7TNB2-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7TNB2-3",
            "url": "https://www.uniprot.org/uniprot/Q7TNB2-3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7TNB2-4",
            "url": "https://www.uniprot.org/uniprot/Q7TNB2-4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSDTEEQEYEEEQAEDEEAVEEEAPEEPEPVAEREEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLREKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK",
        "length": 261,
        "header": "sp|Q7TNB2-1|TNNT1_RAT Isoform 1 of Troponin T, slow skeletal muscle  OS=Rattus norvegicus OX=10116 GN=Tnnt1 PE=1 SV=3 CANONICAL=Q7TNB2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I5YBH8-1",
            "url": "",
            "sequence": {
                "sequence": "MQSGGAPEEPEPVAEREEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLREKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK",
                "length": 241,
                "header": "tr|A0A8I5YBH8-1|TNNT1_RAT Computationally mapped isoform of Troponin T, slow skeletal muscle  OS=Rattus norvegicus OX=10116 GN=Tnnt1 PE=1 SV=1 CANONICAL=Q7TNB2-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 69316616,
                "end_pos": 69308154,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000101852.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000101852.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000076828.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000076828.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q7TNB2-1",
            "url": "",
            "sequence": {
                "sequence": "MSDTEEQEYEEEQAEDEEAVEEEAPEEPEPVAEREEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLREKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK",
                "length": 261,
                "header": "sp|Q7TNB2-1|TNNT1_RAT Isoform 1 of Troponin T, slow skeletal muscle  OS=Rattus norvegicus OX=10116 GN=Tnnt1 PE=1 SV=3 CANONICAL=Q7TNB2-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 69316616,
                "end_pos": 69308115,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000034957",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000034957"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000038327",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000038327"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q7TNB2-2",
            "url": "",
            "sequence": {
                "sequence": "MSDTEEQEYEEEQAEDEEAVEEEAPEEPEPVAEREERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLREKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK",
                "length": 260,
                "header": "sp|Q7TNB2-2|TNNT1_RAT Isoform 2 of Troponin T, slow skeletal muscle  OS=Rattus norvegicus OX=10116 GN=Tnnt1 PE=1 SV=3 CANONICAL=Q7TNB2-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "Q7TNB2-3",
            "url": "",
            "sequence": {
                "sequence": "MSDTEEQEYEEEQAEDEEAVEEEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLREKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK",
                "length": 249,
                "header": "sp|Q7TNB2-3|TNNT1_RAT Isoform 3 of Troponin T, slow skeletal muscle  OS=Rattus norvegicus OX=10116 GN=Tnnt1 PE=1 SV=3 CANONICAL=Q7TNB2-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "Q7TNB2-4",
            "url": "",
            "sequence": {
                "sequence": "MSDTEEQEYEEEQAEDEEAVEEEEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLREKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK",
                "length": 250,
                "header": "sp|Q7TNB2-4|TNNT1_RAT Isoform 4 of Troponin T, slow skeletal muscle  OS=Rattus norvegicus OX=10116 GN=Tnnt1 PE=1 SV=3 CANONICAL=Q7TNB2-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 69316616,
                "end_pos": 69308115,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000058843",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000058843"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000055633",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000055633"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 2,
            "end_pos": 2,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine; by CK2",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7TNB2",
                    "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                }
            ],
            "site_lbl": "Ser2"
        }
    ],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Expression and functional properties of four slow skeletal troponin T isoforms in rat muscles.",
            "journal": "Am. J. Physiol.",
            "date": "2005",
            "authors": "Kischel P, Bastide B, Muller M, Dubail F, Offredi F, Jin JP, Mounier Y, Martial J",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7TNB2",
                    "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15788488",
                    "url": "https://glygen.org/publication/PubMed/15788488"
                }
            ]
        },
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.",
            "journal": "Nat. Commun.",
            "date": "2012",
            "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7TNB2",
                    "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:171409",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:171409",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-390522",
            "name": "Striated Muscle Contraction",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-390522",
            "resource": "Reactome",
            "description": "Striated Muscle Contraction"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "O88346-1",
            "protein_name": "Troponin T, slow skeletal muscle",
            "gene_name": "Tnnt1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSDTEEQEYEEEQAEDEEAVEEEEAPEEPEPVAEREEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLREKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK",
                "length": 262
            },
            "evidence": [
                {
                    "id": "45234685",
                    "url": "http://www.informatics.jax.org/homology/45234685",
                    "database": "MGI"
                },
                {
                    "id": "Q7TNB2",
                    "url": "https://omabrowser.org/oma/group/Q7TNB2/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P13805-1",
            "protein_name": "Troponin T, slow skeletal muscle",
            "gene_name": "TNNT1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK",
                "length": 278
            },
            "evidence": [
                {
                    "id": "45234685",
                    "url": "http://www.informatics.jax.org/homology/45234685",
                    "database": "MGI"
                },
                {
                    "id": "Q7TNB2",
                    "url": "https://omabrowser.org/oma/group/Q7TNB2/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 6,
                "go_terms": [
                    {
                        "name": "regulation of muscle contraction",
                        "id": "GO:0006937",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006937",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TNB2",
                                "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "skeletal muscle contraction",
                        "id": "GO:0003009",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TNB2",
                                "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "transition between fast and slow fiber",
                        "id": "GO:0014883",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014883",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TNB2",
                                "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "sarcomere organization",
                        "id": "GO:0045214",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TNB2",
                                "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "slow-twitch skeletal muscle fiber contraction",
                        "id": "GO:0031444",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031444",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TNB2",
                                "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of muscle contraction",
                        "id": "GO:0045932",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045932",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TNB2",
                                "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "troponin complex",
                        "id": "GO:0005861",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005861",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TNB2",
                                "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "troponin T binding",
                        "id": "GO:0031014",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031014",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TNB2",
                                "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "tropomyosin binding",
                        "id": "GO:0005523",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005523",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7TNB2",
                                "url": "https://www.uniprot.org/uniprot/Q7TNB2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                }
            ],
            "sort_fields": [
                "start_pos",
                "end_pos",
                "kinase_uniprot_canonical_ac",
                "kinase_gene_name",
                "residue",
                "comment",
                "site_lbl"
            ]
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 2
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}
