{
    "uniprot_canonical_ac": "Q7KGG1-1",
    "uniprot_ac": "Q7KGG1",
    "uniprot_id": "Q7KGG1_DROME",
    "mass": {
        "chemical_mass": 62305.0,
        "monoisotopic_mass": 62305.0
    },
    "refseq": {
        "ac": "NP_610977",
        "name": "adenosine deaminase-related growth factor E",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610977"
    },
    "gene_names": [
        {
            "name": "Adgf-E",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1",
            "id": "Q7KGG1"
        },
        {
            "name": "ADGF-E; adgfe; CG10143; Dmel\\CG10143",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610977",
            "id": "NP_610977"
        },
        {
            "name": "ADGF-E",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1",
            "id": "Q7KGG1"
        },
        {
            "name": "Adgf-E-RA",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1",
            "id": "Q7KGG1"
        },
        {
            "name": "Adgf-E",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610977",
            "id": "NP_610977"
        },
        {
            "name": "CG10143",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1",
            "id": "Q7KGG1"
        },
        {
            "name": "Dmel\\CG10143",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1",
            "id": "Q7KGG1"
        },
        {
            "name": "Dmel_CG10143",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1",
            "id": "Q7KGG1"
        },
        {
            "name": "adgfe",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1",
            "id": "Q7KGG1"
        }
    ],
    "protein_names": [
        {
            "name": "adenosine deaminase",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q7KGG1"
        },
        {
            "name": "3.5.4.4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q7KGG1"
        },
        {
            "name": "CG10143-PA; Adgf-E-PA",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610977",
            "id": "NP_610977"
        },
        {
            "name": "adenosine deaminase-related growth factor E",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610977",
            "id": "NP_610977"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:106",
            "recommended_name": {
                "id": "DOID:106",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:106",
                "name": "pleural tuberculosis",
                "description": "An extrapulmonary tuberculosis that results_in lymphocyte-predominant exudative pleural effusion, located_in pleura. This results from an allergic response to tuberculoprotein causing the permeabiltity of the pleural vasculature to alter leading to a sub-pleural caseous focus rupture into the pleural sac."
            },
            "synonyms": [
                {
                    "id": "DOID:106",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:106",
                    "name": "Pearly disease",
                    "description": ""
                },
                {
                    "id": "DOID:106",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:106",
                    "name": "Tuberculosis of pleura",
                    "description": ""
                },
                {
                    "id": "DOID:106",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:106",
                    "name": "Tuberculous pleurisy",
                    "description": ""
                },
                {
                    "id": "DOID:106",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:106",
                    "name": "Tuberculous pleuritis",
                    "description": ""
                },
                {
                    "id": "DOID:106",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:106",
                    "name": "tuberculous pleurisy in primary progressive tuberculosis",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "106",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:106"
                }
            ]
        },
        {
            "disease_id": "DOID:13096",
            "recommended_name": {
                "id": "DOID:13096",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:13096",
                "name": "Sneddon syndrome",
                "description": "An artery disease that is characterized by onset of livedo reticularis in the second decade and onset of cerebrovascular disease in early adulthood and that has_material_basis_in compound heterozygous mutation in the CECR1 gene (ADA2) on chromosome 22q11."
            },
            "synonyms": [
                {
                    "id": "DOID:13096",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:13096",
                    "name": "Idiopathic livedo reticularis with systemic involvement",
                    "description": ""
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "Sneddon syndrome",
                    "description": "Sneddon's syndrome (SS) is a rare non-inflammatory thrombotic vasculopathy characterized by the combination of cerebrovascular disease with livedo racemosa."
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "Ehrmann-Sneddon syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "Sneddon syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "idiopathic livedo reticularis with systemic involvement",
                    "description": ""
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "livedo racemosa-cerebrovascular accident syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "livedo reticularis-cerebrovascular accident syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "Sneddon's syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "cerebro-vascular lesions and livedo reticularis",
                    "description": ""
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "livedo racemosa and cerebrovascular accidents",
                    "description": ""
                },
                {
                    "id": "MONDO:0008436",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008436",
                    "name": "livedo reticularis and cerebrovascular accidents",
                    "description": ""
                },
                {
                    "id": "MIM:182410",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/182410",
                    "name": "Sneddon syndrome",
                    "description": "Sneddon syndrome"
                }
            ],
            "evidence": [
                {
                    "id": "13096",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:13096"
                }
            ]
        },
        {
            "disease_id": "DOID:2957",
            "recommended_name": {
                "id": "DOID:2957",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:2957",
                "name": "pulmonary tuberculosis",
                "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "2957",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:2957"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "Adgf-E",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1",
            "locus": {
                "chromosome": "2R",
                "start_pos": 14656798,
                "end_pos": 14658755,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0033952",
                        "url": "https://www.ensembl.org/id/FBgn0033952"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0033952",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0033952",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd01321",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01321",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "FBgn0033952",
            "url": "https://flybase.org/reports/FBgn0033952",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "36627",
            "url": "https://www.ncbi.nlm.nih.gov/gene/36627",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001365",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001365",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006330",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006330",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006331",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006331",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013659",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013659",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR032466",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG10143",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG10143",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "GHGYTIT",
            "url": "https://omabrowser.org/oma/group/GHGYTIT/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4403at2759",
            "url": "http://www.orthodb.org/?query=4403at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11409",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11409",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11409:SF39",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11409:SF39",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00962",
            "url": "http://pfam.xfam.org/family/PF00962",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF08451",
            "url": "http://pfam.xfam.org/family/PF08451",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_610977",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610977",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "24408",
            "url": "https://www.rhea-db.org/rhea/24408",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "Q7KGG1",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7KGG1-1",
            "url": "https://www.uniprot.org/uniprot/Q7KGG1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MTVLLSHRMLLAGWARRATPTAAQWIHHNPEKMTLLEMLGTTNLRKSTPKDYRILREIFNSFERYSGVGNDIQLTLPERAANELIMCEKKREYEKGIMDPSKFAPGHHIFQVLTKVKKSPLFQILRRMPKGAALKAHDTSMCSSRVVIEITYRDNLWVCTTQNGCRVEEFRFAKDKPKDVSFENGEWQPMEKLRELRGEENLRKYLQMRFSMYPLASFTTNAHAWRHMMGIFGLLDGLLQYAPVWGDYYYNALKEFYADGVQYLEVRSVLPQLYSLDGSRMPKRETVQIYKDTLERFKKEHPGFIDSKLIYAPIRHVQPELVGEYIKECTELNKEFPSFVVGFDLVGQEDVGHPLSNFAAELLKLPDHIHFYFHAGQTNWYGSHVDQNLLDAIVLGTKRIGHGYTITKHPVLMRLAKYLNIALEVCPVSNQVLQLGSDYRSHPAATLIAENVPMVIASGSPGFWRAAPLSHDFYMAFLGIAPMNADLKFLKRTAKNSIKYSSLKDEAKAEAMEKWKKQWDKWVENIVRQRKKDSETEKK",
        "length": 539,
        "header": "tr|Q7KGG1-1|Q7KGG1_DROME Isoform 1 of adenosine deaminase  OS=Drosophila melanogaster OX=7227 GN=Adgf-E PE=2 SV=1 CANONICAL=Q7KGG1-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q7KGG1-1",
            "url": "",
            "sequence": {
                "sequence": "MTVLLSHRMLLAGWARRATPTAAQWIHHNPEKMTLLEMLGTTNLRKSTPKDYRILREIFNSFERYSGVGNDIQLTLPERAANELIMCEKKREYEKGIMDPSKFAPGHHIFQVLTKVKKSPLFQILRRMPKGAALKAHDTSMCSSRVVIEITYRDNLWVCTTQNGCRVEEFRFAKDKPKDVSFENGEWQPMEKLRELRGEENLRKYLQMRFSMYPLASFTTNAHAWRHMMGIFGLLDGLLQYAPVWGDYYYNALKEFYADGVQYLEVRSVLPQLYSLDGSRMPKRETVQIYKDTLERFKKEHPGFIDSKLIYAPIRHVQPELVGEYIKECTELNKEFPSFVVGFDLVGQEDVGHPLSNFAAELLKLPDHIHFYFHAGQTNWYGSHVDQNLLDAIVLGTKRIGHGYTITKHPVLMRLAKYLNIALEVCPVSNQVLQLGSDYRSHPAATLIAENVPMVIASGSPGFWRAAPLSHDFYMAFLGIAPMNADLKFLKRTAKNSIKYSSLKDEAKAEAMEKWKKQWDKWVENIVRQRKKDSETEKK",
                "length": 539,
                "header": "tr|Q7KGG1-1|Q7KGG1_DROME Isoform 1 of adenosine deaminase  OS=Drosophila melanogaster OX=7227 GN=Adgf-E PE=2 SV=1 CANONICAL=Q7KGG1-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 14658665,
                "end_pos": 14656882,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0087482",
                        "url": "https://www.ensembl.org/id/FBtr0087482"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0086611",
                        "url": "https://www.ensembl.org/id/FBpp0086611"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [
        {
            "title": "The genome sequence of Drosophila melanogaster.",
            "journal": "Science",
            "date": "2000",
            "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10731132",
                    "url": "https://glygen.org/publication/PubMed/10731132"
                }
            ]
        },
        {
            "title": "Characterization of the adenosine deaminase-related growth factor (ADGF) gene family in Drosophila.",
            "journal": "Gene",
            "date": "2001",
            "authors": "McDermid H.E., Maier S.A., Locke J., Podemski L., Graham S.W.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11738815",
                    "url": "https://glygen.org/publication/PubMed/11738815"
                }
            ]
        },
        {
            "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537568",
                    "url": "https://glygen.org/publication/PubMed/12537568"
                }
            ]
        },
        {
            "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537572",
                    "url": "https://glygen.org/publication/PubMed/12537572"
                }
            ]
        },
        {
            "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537573",
                    "url": "https://glygen.org/publication/PubMed/12537573"
                }
            ]
        },
        {
            "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537574",
                    "url": "https://glygen.org/publication/PubMed/12537574"
                }
            ]
        },
        {
            "title": "Combined evidence annotation of transposable elements in genome sequences.",
            "journal": "PLoS Comput. Biol.",
            "date": "2005",
            "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16110336",
                    "url": "https://glygen.org/publication/PubMed/16110336"
                }
            ]
        },
        {
            "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.",
            "journal": "Science",
            "date": "2007",
            "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17569856",
                    "url": "https://glygen.org/publication/PubMed/17569856"
                }
            ]
        },
        {
            "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.",
            "journal": "Science",
            "date": "2007",
            "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17569867",
                    "url": "https://glygen.org/publication/PubMed/17569867"
                }
            ]
        },
        {
            "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.",
            "journal": "Genome Res.",
            "date": "2015",
            "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "25589440",
                    "url": "https://glygen.org/publication/PubMed/25589440"
                }
            ]
        },
        {
            "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.",
            "journal": "G3 (Bethesda)",
            "date": "2015",
            "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "26109356",
                    "url": "https://glygen.org/publication/PubMed/26109356"
                }
            ]
        },
        {
            "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.",
            "journal": "G3 (Bethesda)",
            "date": "2015",
            "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KGG1",
                    "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "26109357",
                    "url": "https://glygen.org/publication/PubMed/26109357"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "dme:Dmel_CG10143",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG10143",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "extracellular space",
                        "id": "GO:0005615",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7KGG1",
                                "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "inosine biosynthetic process",
                        "id": "GO:0046103",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046103",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q7KGG1",
                                "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [
        {
            "id": "24408",
            "name": "",
            "equation": "adenosine + H(+) + H2O = inosine + NH4(+)",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q920P6-1",
                "P00813-1",
                "Q9NZK5-1",
                "Q8IV20-1",
                "P03958-1",
                "Q8BZT9-1",
                "Q553U5-1",
                "Q54KF3-1",
                "Q8IQR3-1",
                "Q9VVK5-1",
                "Q9VFS1-1",
                "Q7KGG1-1",
                "Q9VFS0-1",
                "Q9VVK4-1"
            ],
            "evidence": [
                {
                    "id": "24408",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/24408"
                }
            ]
        }
    ],
    "reaction_participants": [],
    "reaction_enzymes": [
        {
            "uniprot_ac": "P00813",
            "gene_name": "ADA",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "P00813",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00813"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P00813",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00813"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P03958",
            "gene_name": "Ada",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "P03958",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P03958"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P03958",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P03958"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54KF3",
            "gene_name": "ada",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q54KF3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54KF3"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54KF3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54KF3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q553U5",
            "gene_name": "ADA2",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q553U5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q553U5"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q553U5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q553U5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q7KGG1",
            "gene_name": "Adgf-E",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q7KGG1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q7KGG1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q7KGG1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8BZT9",
            "gene_name": "Lacc1",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q8BZT9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BZT9"
                        }
                    ]
                },
                {
                    "ec_number": "2.4.2.1",
                    "activity": "a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase.",
                    "evidence": [
                        {
                            "id": "Q8BZT9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BZT9"
                        }
                    ]
                },
                {
                    "ec_number": "2.4.2.28",
                    "activity": "phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate.",
                    "evidence": [
                        {
                            "id": "Q8BZT9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BZT9"
                        }
                    ]
                },
                {
                    "ec_number": "2.4.2.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8BZT9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BZT9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8IQR3",
            "gene_name": "Adgf-A2",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q8IQR3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8IQR3"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8IQR3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8IQR3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8IV20",
            "gene_name": "LACC1",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q8IV20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8IV20"
                        }
                    ]
                },
                {
                    "ec_number": "2.4.2.1",
                    "activity": "a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase.",
                    "evidence": [
                        {
                            "id": "Q8IV20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8IV20"
                        }
                    ]
                },
                {
                    "ec_number": "2.4.2.28",
                    "activity": "phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate.",
                    "evidence": [
                        {
                            "id": "Q8IV20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8IV20"
                        }
                    ]
                },
                {
                    "ec_number": "2.4.2.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8IV20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8IV20"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q920P6",
            "gene_name": "Ada",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q920P6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q920P6"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q920P6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q920P6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9NZK5",
            "gene_name": "ADA2",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q9NZK5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9NZK5"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9NZK5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9NZK5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9VFS0",
            "gene_name": "Adgf-C",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q9VFS0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9VFS0"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9VFS0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9VFS0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9VFS1",
            "gene_name": "Adgf-D",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q9VFS1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9VFS1"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9VFS1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9VFS1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9VVK4",
            "gene_name": "Adgf-B",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q9VVK4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9VVK4"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9VVK4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9VVK4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9VVK5",
            "gene_name": "Adgf-A",
            "activity": [
                {
                    "ec_number": "3.5.4.4",
                    "activity": "2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+).",
                    "evidence": [
                        {
                            "id": "Q9VVK5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9VVK5"
                        }
                    ]
                },
                {
                    "ec_number": "3.5.4.4",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9VVK5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9VVK5"
                        }
                    ]
                }
            ]
        }
    ],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 12
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}
