{
    "uniprot_canonical_ac": "Q76NS2-1",
    "uniprot_ac": "Q76NS2",
    "uniprot_id": "Q76NS2_DROME",
    "mass": {
        "chemical_mass": 117782.0,
        "monoisotopic_mass": 117782.0
    },
    "refseq": {
        "ac": "NP_001259472",
        "name": "uncharacterized protein, isoform I",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259472"
    },
    "gene_names": [
        {
            "name": "Dmel\\CG10353",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q76NS2",
            "id": "Q76NS2"
        },
        {
            "name": "CG10353-RC",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q76NS2",
            "id": "Q76NS2"
        },
        {
            "name": "CG10353",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259472",
            "id": "NP_001259472"
        },
        {
            "name": "CG10353",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q76NS2",
            "id": "Q76NS2"
        },
        {
            "name": "Dmel\\CG10353",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259472",
            "id": "NP_001259472"
        },
        {
            "name": "Dmel_CG10353",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q76NS2",
            "id": "Q76NS2"
        }
    ],
    "protein_names": [
        {
            "name": "Anoctamin",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q76NS2"
        },
        {
            "name": "CG10353-PE",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245633",
            "id": "NP_001245633"
        },
        {
            "name": "CG10353-PI",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259472",
            "id": "NP_001259472"
        },
        {
            "name": "CG10353-PK",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259473",
            "id": "NP_001259473"
        },
        {
            "name": "CG10353-PL",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259470",
            "id": "NP_001259470"
        },
        {
            "name": "uncharacterized protein, isoform E",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245633",
            "id": "NP_001245633"
        },
        {
            "name": "uncharacterized protein, isoform I",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259472",
            "id": "NP_001259472"
        },
        {
            "name": "uncharacterized protein, isoform K",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259473",
            "id": "NP_001259473"
        },
        {
            "name": "uncharacterized protein, isoform L",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259470",
            "id": "NP_001259470"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0110284",
            "recommended_name": {
                "id": "DOID:0110284",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0110284",
                "name": "autosomal recessive limb-girdle muscular dystrophy type 2L",
                "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the ANO5 gene on chromosome 11p14."
            },
            "synonyms": [
                {
                    "id": "DOID:0110284",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110284",
                    "name": "LGMD2L",
                    "description": ""
                },
                {
                    "id": "DOID:0110284",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110284",
                    "name": "muscular dystrophy, limb-girdle, type 2L",
                    "description": ""
                },
                {
                    "id": "MONDO:0012652",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012652",
                    "name": "autosomal recessive limb-girdle muscular dystrophy type 2L",
                    "description": "A form of limb-girdle muscular dystrophy most often characterized by an adult onset (but ranging from 11 to 51 years) of mainly proximal lower limb weakness, with difficulties standing on tiptoes being one of the initial signs. Proximal upper limb and distal lower limb weakness is also common as well as atrophy of the quadriceps (most commonly), biceps brachii, and lower leg muscles. However, calf hypertrophy has also been reported in some cases. LGMD2L progresses slowly, with most patients remaining ambulatory until late adulthood."
                },
                {
                    "id": "MONDO:0012652",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012652",
                    "name": "ANO5 autosomal recessive limb-girdle muscular dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0012652",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012652",
                    "name": "LGMD2L",
                    "description": ""
                },
                {
                    "id": "MONDO:0012652",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012652",
                    "name": "autosomal recessive limb-girdle muscular dystrophy caused by mutation in ANO5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012652",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012652",
                    "name": "muscular dystrophy, limb-girdle, autosomal recessive 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012652",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012652",
                    "name": "muscular dystrophy, limb-girdle, type 2L",
                    "description": ""
                },
                {
                    "id": "MONDO:0012652",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012652",
                    "name": "limb-girdle muscular dystrophy type 2L",
                    "description": ""
                },
                {
                    "id": "MIM:611307",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611307",
                    "name": "Muscular dystrophy, limb-girdle, autosomal recessive 12",
                    "description": "Muscular dystrophy, limb-girdle, autosomal recessive 12"
                }
            ],
            "evidence": [
                {
                    "id": "0110284",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110284"
                }
            ]
        },
        {
            "disease_id": "DOID:0111533",
            "recommended_name": {
                "id": "DOID:0111533",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111533",
                "name": "gnathodiaphyseal dysplasia",
                "description": "An osteochondrodysplasia characterized by cementoosseous lesions of the jawbones, bone fragility, bowing/cortical thickening of tubular bones, and diaphyseal sclerosis of long bones that has_material_basis_in heterozygous mutation in the ANO5 gene on chromosome 11p14.3."
            },
            "synonyms": [
                {
                    "id": "DOID:0111533",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111533",
                    "name": "GDD",
                    "description": ""
                },
                {
                    "id": "DOID:0111533",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111533",
                    "name": "Levin syndrome 2",
                    "description": ""
                },
                {
                    "id": "DOID:0111533",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111533",
                    "name": "gnathodiaphyseal sclerosis",
                    "description": ""
                },
                {
                    "id": "DOID:0111533",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111533",
                    "name": "osteogenesis imperfecta, Levin type",
                    "description": ""
                },
                {
                    "id": "DOID:0111533",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111533",
                    "name": "osteogenesis imperfecta with unusual skeletal lesions",
                    "description": ""
                },
                {
                    "id": "MONDO:0008151",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008151",
                    "name": "gnathodiaphyseal dysplasia",
                    "description": "Gnathodiaphyseal dysplasia (GDD) is a bone dysplasia characterized by bone fragility, frequent bone fractures at a young age, cemento-osseous lesions of the jaw bones, bowing of tubular bones (tibia and fibula) and diaphyseal sclerosis of long bones associated with generalized osteopenia. GD follows an autosomal dominant mode of transmission."
                },
                {
                    "id": "MONDO:0008151",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008151",
                    "name": "GDD",
                    "description": ""
                },
                {
                    "id": "MONDO:0008151",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008151",
                    "name": "gnathodiaphyseal dysplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0008151",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008151",
                    "name": "GNATHODIAPHYSEAL dysplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0008151",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008151",
                    "name": "Gnathodiaphyseal sclerosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0008151",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008151",
                    "name": "Levin syndrome 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0008151",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008151",
                    "name": "osteogenesis imperfecta Levin type",
                    "description": ""
                },
                {
                    "id": "MONDO:0008151",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008151",
                    "name": "osteogenesis imperfecta with unusual skeletal lesions",
                    "description": ""
                },
                {
                    "id": "MIM:166260",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/166260",
                    "name": "Gnathodiaphyseal dysplasia",
                    "description": "Gnathodiaphyseal dysplasia"
                }
            ],
            "evidence": [
                {
                    "id": "0111533",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111533"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q76NS2",
                    "url": "https://www.uniprot.org/uniprot/Q76NS2"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "Dmel\\CG10353",
            "url": "https://www.uniprot.org/uniprot/Q76NS2",
            "locus": {
                "chromosome": "X",
                "start_pos": 11877737,
                "end_pos": 11887162,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0030349",
                        "url": "https://www.ensembl.org/id/FBgn0030349"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0030349",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0030349",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "FBgn0030349",
            "url": "https://flybase.org/reports/FBgn0030349",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "32148",
            "url": "https://www.ncbi.nlm.nih.gov/gene/32148",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q9VYS8",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VYS8*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR007632",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007632",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR032394",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032394",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG10353",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG10353",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "DDPHPYK",
            "url": "https://omabrowser.org/oma/group/DDPHPYK/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "534027at2759",
            "url": "http://www.orthodb.org/?query=534027at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12308",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12308:SF85",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308:SF85",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF04547",
            "url": "http://pfam.xfam.org/family/PF04547",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF16178",
            "url": "http://pfam.xfam.org/family/PF16178",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-2672351",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2672351",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001245633",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245633",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "M9PGX9",
            "url": "https://www.uniprot.org/uniprot/M9PGX9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "M9PGX9-1",
            "url": "https://www.uniprot.org/uniprot/M9PGX9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "M9PJJ8",
            "url": "https://www.uniprot.org/uniprot/M9PJJ8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "M9PJJ8-1",
            "url": "https://www.uniprot.org/uniprot/M9PJJ8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q76NS2",
            "url": "https://www.uniprot.org/uniprot/Q76NS2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q76NS2-1",
            "url": "https://www.uniprot.org/uniprot/Q76NS2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9VYS8",
            "url": "https://www.uniprot.org/uniprot/Q9VYS8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9VYS8-1",
            "url": "https://www.uniprot.org/uniprot/Q9VYS8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MYSAVRTNDYDYPESEMDERESLYFDTISLAESEAAAAAAAHRKSISQSRNTIYHSAVDLAGDEGGGGSGGGRLRLGGGAAAEHAALAWQPGYRQSTALEHLNGGGGGGGDHTDAAIAAQMIALQNGRNHLPTGIGVTGDGGQGGGDDEVSRRLLRTSSNISNKDKKLPITYSQWKSRTYRRFDDGKRSVDFVLAYNGETQLEEHRRKCEIFEANLQREGLQLEHNKVQRVHFIKIHAPAEVLYRYAEILKIKVPLKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNTALFPEREPRIHLEFSRNYLELYDTEHPNFLDASTRYSIINFILQRQRFVEGEETADNLGIEKLVQDGVYTCAYTLHDKDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQDHTGKRTILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCMQLVIIMAGKQAVNAIVEMLIPYLMRTFKELSYRHGWYKSHQDQRLVPYNQFTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMGDPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTELNGQQKSEGELRQRNNETVIRNRDEATSFV",
        "length": 1029,
        "header": "tr|Q76NS2-1|Q76NS2_DROME Isoform 1 of Anoctamin  OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG10353 PE=3 SV=2 CANONICAL=Q76NS2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "M9PGX9-1",
            "url": "",
            "sequence": {
                "sequence": "MDERESLYFDTISLAESEAAAAAAAHRKSISQSRNTIYHSAVDLAGDEGGGGSGGGRLRLGGGAAAEHAALAWQPGYRQSTALEHLNGGGGGGGDHTDAAIAAQMIALQNGRNHLPTGIGVTGDGGQGGGDDEVSRRLLRTSSNISNKDKKLPITYSQWKSRTYRRFDDGKRSVDFVLAYNGETQLEEHRRKCEIFEANLQREGLQLEHNKVQRVHFIKIHAPAEVLYRYAEILKIKVPLKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNTALFPEREPRIHLEFSRNYLELYDTEHPNFLDASTRYSIINFILQRQRFVEGEETADNLGIEKLVQDGVYTCAYTLHDKDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQDHTGKRTILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCMQLVIIMAGKQAVNAIVEMLIPYLMRTFKELSYRHGWYKSHQDQRLVPYNQFTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMGDPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTELNGQQKSEGELRQRNNETVIRNRDEATSFV",
                "length": 1013,
                "header": "tr|M9PGX9-1|M9PGX9_DROME Computationally mapped isoform of Anoctamin  OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG10353 PE=3 SV=1 CANONICAL=Q76NS2-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 11883586,
                "end_pos": 11878746,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0344703",
                        "url": "https://www.ensembl.org/id/FBtr0344703"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0311036",
                        "url": "https://www.ensembl.org/id/FBpp0311036"
                    }
                ]
            }
        },
        {
            "isoform_ac": "M9PJJ8-1",
            "url": "",
            "sequence": {
                "sequence": "MYSAVRTNDYDYPESEMDERESLYFDTISLAESEAAAAAAAHRKSISQSRNTIYHSAVDLAGDEGGGGSGGGRLRLGGGAAAEHAALAWQPGYRQSTALEHLNGGGGGGGDHTDAAIAAQMIALQNGRNHLPTGIGVTGDGGQGGGDDETYRRFDDGKRSVDFVLAYNGETQLEEHRRKCEIFEANLQREGLQLEHNKVQRVHFIKIHAPAEVLYRYAEILKIKVPLKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNTALFPEREPRIHLEFSRNYLELYDTEHPNFLDASTRYSIINFILQRQRFVEGEETADNLGIEKLVQDGVYTCAYTLHDKDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQDHTGKRTILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCMQLVIIMAGKQAVNAIVEMLIPYLMRTFKELSYRHGWYKSHQDQRLVPYNQFTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMGDPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTELNGQQKSEGELRQRNNETVIRNRDEATSFV",
                "length": 1000,
                "header": "tr|M9PJJ8-1|Q76NS2_DROME Computationally mapped isoform of Anoctamin  OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG10353 PE=3 SV=2 CANONICAL=Q76NS2-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 11884810,
                "end_pos": 11878746,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0344702",
                        "url": "https://www.ensembl.org/id/FBtr0344702"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0311035",
                        "url": "https://www.ensembl.org/id/FBpp0311035"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q76NS2-1",
            "url": "",
            "sequence": {
                "sequence": "MYSAVRTNDYDYPESEMDERESLYFDTISLAESEAAAAAAAHRKSISQSRNTIYHSAVDLAGDEGGGGSGGGRLRLGGGAAAEHAALAWQPGYRQSTALEHLNGGGGGGGDHTDAAIAAQMIALQNGRNHLPTGIGVTGDGGQGGGDDEVSRRLLRTSSNISNKDKKLPITYSQWKSRTYRRFDDGKRSVDFVLAYNGETQLEEHRRKCEIFEANLQREGLQLEHNKVQRVHFIKIHAPAEVLYRYAEILKIKVPLKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNTALFPEREPRIHLEFSRNYLELYDTEHPNFLDASTRYSIINFILQRQRFVEGEETADNLGIEKLVQDGVYTCAYTLHDKDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQDHTGKRTILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCMQLVIIMAGKQAVNAIVEMLIPYLMRTFKELSYRHGWYKSHQDQRLVPYNQFTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMGDPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTELNGQQKSEGELRQRNNETVIRNRDEATSFV",
                "length": 1029,
                "header": "tr|Q76NS2-1|Q76NS2_DROME Isoform 1 of Anoctamin  OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG10353 PE=3 SV=2 CANONICAL=Q76NS2-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 11884810,
                "end_pos": 11878746,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0114452",
                        "url": "https://www.ensembl.org/id/FBtr0114452"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0112944",
                        "url": "https://www.ensembl.org/id/FBpp0112944"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9VYS8-1",
            "url": "",
            "sequence": {
                "sequence": "MDERESLYFDTISLAESEAAAAAAAHRKSISQSRNTIYHSAVDLAGDEGGGGSGGGRLRLGGGAAAEHAALAWQPGYRQSTALEHLNGGGGGGGDHTDAAIAAQMIALQNGRNHLPTGIGVTGDGGQGGGDDETYRRFDDGKRSVDFVLAYNGETQLEEHRRKCEIFEANLQREGLQLEHNKVQRVHFIKIHAPAEVLYRYAEILKIKVPLKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNTALFPEREPRIHLEFSRNYLELYDTEHPNFLDASTRYSIINFILQRQRFVEGEETADNLGIEKLVQDGVYTCAYTLHDKDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQDHTGKRTILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCMQLVIIMAGKQAVNAIVEMLIPYLMRTFKELSYRHGWYKSHQDQRLVPYNQFTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMGDPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTELNGQQKSEGELRQRNNETVIRNRDEATSFV",
                "length": 984,
                "header": "tr|Q9VYS8-1|Q76NS2_DROME Computationally mapped isoform of Anoctamin  OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG10353 PE=3 SV=3 CANONICAL=Q76NS2-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 11883586,
                "end_pos": 11878746,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0114451",
                        "url": "https://www.ensembl.org/id/FBtr0114451"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0112943",
                        "url": "https://www.ensembl.org/id/FBpp0112943"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The genome sequence of Drosophila melanogaster.",
            "journal": "Science",
            "date": "2000",
            "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9VYS8",
                    "url": "https://www.uniprot.org/uniprot/Q9VYS8"
                },
                {
                    "database": "UniProtKB",
                    "id": "M9PJJ8",
                    "url": "https://www.uniprot.org/uniprot/M9PJJ8"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q76NS2",
                    "url": "https://www.uniprot.org/uniprot/Q76NS2"
                },
                {
                    "database": "UniProtKB",
                    "id": "M9PGX9",
                    "url": "https://www.uniprot.org/uniprot/M9PGX9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10731132",
                    "url": "https://glygen.org/publication/PubMed/10731132"
                }
            ]
        },
        {
            "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9VYS8",
                    "url": "https://www.uniprot.org/uniprot/Q9VYS8"
                },
                {
                    "database": "UniProtKB",
                    "id": "M9PJJ8",
                    "url": "https://www.uniprot.org/uniprot/M9PJJ8"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q76NS2",
                    "url": "https://www.uniprot.org/uniprot/Q76NS2"
                },
                {
                    "database": "UniProtKB",
                    "id": "M9PGX9",
                    "url": "https://www.uniprot.org/uniprot/M9PGX9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537568",
                    "url": "https://glygen.org/publication/PubMed/12537568"
                }
            ]
        },
        {
            "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9VYS8",
                    "url": "https://www.uniprot.org/uniprot/Q9VYS8"
                },
                {
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                    "id": "M9PJJ8",
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                },
                {
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                    "id": "Q76NS2",
                    "url": "https://www.uniprot.org/uniprot/Q76NS2"
                },
                {
                    "database": "UniProtKB",
                    "id": "M9PGX9",
                    "url": "https://www.uniprot.org/uniprot/M9PGX9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537572",
                    "url": "https://glygen.org/publication/PubMed/12537572"
                }
            ]
        },
        {
            "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE",
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                {
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                    "id": "Q76NS2",
                    "url": "https://www.uniprot.org/uniprot/Q76NS2"
                },
                {
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                {
                    "type": "PubMed",
                    "id": "12537573",
                    "url": "https://glygen.org/publication/PubMed/12537573"
                }
            ]
        },
        {
            "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH",
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                {
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                },
                {
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                    "id": "Q76NS2",
                    "url": "https://www.uniprot.org/uniprot/Q76NS2"
                },
                {
                    "database": "UniProtKB",
                    "id": "M9PGX9",
                    "url": "https://www.uniprot.org/uniprot/M9PGX9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537574",
                    "url": "https://glygen.org/publication/PubMed/12537574"
                }
            ]
        },
        {
            "title": "Combined evidence annotation of transposable elements in genome sequences.",
            "journal": "PLoS Comput. Biol.",
            "date": "2005",
            "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9VYS8",
                    "url": "https://www.uniprot.org/uniprot/Q9VYS8"
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                {
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                    "id": "M9PJJ8",
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                },
                {
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                    "id": "Q76NS2",
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                },
                {
                    "database": "UniProtKB",
                    "id": "M9PGX9",
                    "url": "https://www.uniprot.org/uniprot/M9PGX9"
                }
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            "reference": [
                {
                    "type": "PubMed",
                    "id": "16110336",
                    "url": "https://glygen.org/publication/PubMed/16110336"
                }
            ]
        },
        {
            "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.",
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            "date": "2007",
            "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH",
            "evidence": [
                {
                    "database": "UniProtKB",
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                {
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                {
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                },
                {
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                {
                    "type": "PubMed",
                    "id": "17569856",
                    "url": "https://glygen.org/publication/PubMed/17569856"
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            ]
        },
        {
            "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.",
            "journal": "Science",
            "date": "2007",
            "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE",
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                {
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                    "id": "17569867",
                    "url": "https://glygen.org/publication/PubMed/17569867"
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            ]
        },
        {
            "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.",
            "journal": "Genome Res.",
            "date": "2015",
            "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE",
            "evidence": [
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                {
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            ]
        },
        {
            "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.",
            "journal": "G3 (Bethesda)",
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            "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM",
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            ]
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        {
            "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.",
            "journal": "G3 (Bethesda)",
            "date": "2015",
            "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM",
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            ]
        }
    ],
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        {
            "id": "dme:Dmel_CG10353",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG10353",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-DME-2672351",
            "name": "Stimuli-sensing channels",
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            "resource": "Reactome",
            "description": "Stimuli-sensing channels"
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    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
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                                "database": "UniProtKB",
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