{
    "uniprot_canonical_ac": "Q75Q39-1",
    "uniprot_ac": "Q75Q39",
    "uniprot_id": "TOM70_RAT",
    "mass": {
        "chemical_mass": 67445.0,
        "monoisotopic_mass": 67445.0
    },
    "refseq": {
        "ac": "NP_997684",
        "name": "mitochondrial import receptor subunit TOM70",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997684"
    },
    "gene_names": [
        {
            "name": "Tomm70",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q75Q39",
            "id": "Q75Q39"
        },
        {
            "name": "TOM70; Tomm70a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997684",
            "id": "NP_997684"
        },
        {
            "name": "Tomm70a",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q75Q39",
            "id": "Q75Q39"
        },
        {
            "name": "Tomm70",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997684",
            "id": "NP_997684"
        }
    ],
    "protein_names": [
        {
            "name": "Mitochondrial import receptor subunit TOM70",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q75Q39"
        },
        {
            "name": "Mitochondrial precursor proteins import receptor",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q75Q39"
        },
        {
            "name": "Translocase of outer membrane 70 kDa subunit",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q75Q39"
        },
        {
            "name": "Translocase of outer mitochondrial membrane protein 70",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q75Q39"
        },
        {
            "name": "mitochondrial import receptor subunit TOM70",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997684",
            "id": "NP_997684"
        },
        {
            "name": "translocase of outer membrane 70 kDa subunit; mitochondrial precursor proteins import receptor; translocase of outer mitochondrial membrane protein 70",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997684",
            "id": "NP_997684"
        }
    ],
    "function": [
        {
            "annotation": "Acts as receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed:11956321, PubMed:19401463). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "O94826",
                    "url": "https://www.uniprot.org/uniprot/O94826#function"
                },
                {
                    "database": "PubMed",
                    "id": "11956321",
                    "url": "https://glygen.org/publication/PubMed/11956321"
                },
                {
                    "database": "PubMed",
                    "id": "19401463",
                    "url": "https://glygen.org/publication/PubMed/19401463"
                }
            ]
        },
        {
            "annotation": "Adenosine-induced translocation of PKCepsilon to mitochondria is mediated by a caveolin-3-dependent mechanism and this process is age-related, possibly in part, through regulation of HSP90 and TOM70 expression",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_997684",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997684"
                },
                {
                    "database": "PubMed",
                    "id": "27919679",
                    "url": "https://glygen.org/publication/PubMed/27919679"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:1459",
            "recommended_name": {
                "id": "DOID:1459",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:1459",
                "name": "hypothyroidism",
                "description": "A thyroid gland disease which involves an underproduction of thyroid hormone."
            },
            "synonyms": [
                {
                    "id": "DOID:1459",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1459",
                    "name": "Thyroid deficiency",
                    "description": ""
                },
                {
                    "id": "DOID:1459",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1459",
                    "name": "Thyroid insufficiency",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "1459",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:1459"
                }
            ]
        },
        {
            "disease_id": "DOID:6000",
            "recommended_name": {
                "id": "DOID:6000",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:6000",
                "name": "congestive heart failure",
                "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body."
            },
            "synonyms": [
                {
                    "id": "DOID:6000",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:6000",
                    "name": "CHF",
                    "description": ""
                },
                {
                    "id": "DOID:6000",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:6000",
                    "name": "Cardiac Failure Congestive",
                    "description": ""
                },
                {
                    "id": "DOID:6000",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:6000",
                    "name": "Congestive heart disease",
                    "description": ""
                },
                {
                    "id": "DOID:6000",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:6000",
                    "name": "Weak heart",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "6000",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:6000"
                }
            ]
        },
        {
            "disease_id": "DOID:700",
            "recommended_name": {
                "id": "DOID:700",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:700",
                "name": "mitochondrial metabolism disease",
                "description": "An inherited metabolic disorder that involves mitochondrial metabolism dysfunction."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "700",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:700"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Tomm70",
            "url": "https://www.uniprot.org/uniprot/Q75Q39",
            "locus": {
                "chromosome": "11",
                "start_pos": 43377216,
                "end_pos": 43417202,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000001640",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000001640"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000001640",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000001640",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "304017",
            "url": "https://www.ncbi.nlm.nih.gov/gene/304017",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q75Q39",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q75Q39*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR001440",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001440",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011990",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR019734",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:304017",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304017",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "QWRGDIE",
            "url": "https://omabrowser.org/oma/group/QWRGDIE/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1083789at2759",
            "url": "http://www.orthodb.org/?query=1083789at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR46208",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46208",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR46208:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46208:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00515",
            "url": "http://pfam.xfam.org/family/PF00515",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13174",
            "url": "http://pfam.xfam.org/family/PF13174",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13181",
            "url": "http://pfam.xfam.org/family/PF13181",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q75Q39",
            "url": "http://purl.obolibrary.org/obo/PR_Q75Q39",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-RNO-168928",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-168928",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-5205685",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5205685",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-5689880",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5689880",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_997684",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997684",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1303049",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1303049",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "Q75Q39",
            "url": "https://www.uniprot.org/uniprot/Q75Q39",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q75Q39-1",
            "url": "https://www.uniprot.org/uniprot/Q75Q39-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R9PXR4",
            "url": "https://www.uniprot.org/uniprot/R9PXR4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R9PXR4-1",
            "url": "https://www.uniprot.org/uniprot/R9PXR4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAASKPVEAAMAAAAAPASGNGVGSSGGTAAPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGPDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL",
        "length": 610,
        "header": "sp|Q75Q39-1|TOM70_RAT Isoform 1 of Mitochondrial import receptor subunit TOM70  OS=Rattus norvegicus OX=10116 GN=Tomm70 PE=1 SV=1 CANONICAL=Q75Q39-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q75Q39-1",
            "url": "",
            "sequence": {
                "sequence": "MAASKPVEAAMAAAAAPASGNGVGSSGGTAAPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGPDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL",
                "length": 610,
                "header": "sp|Q75Q39-1|TOM70_RAT Isoform 1 of Mitochondrial import receptor subunit TOM70  OS=Rattus norvegicus OX=10116 GN=Tomm70 PE=1 SV=1 CANONICAL=Q75Q39-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 43417021,
                "end_pos": 43379016,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000002238",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000002238"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000002238",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000002238"
                    }
                ]
            }
        },
        {
            "isoform_ac": "R9PXR4-1",
            "url": "",
            "sequence": {
                "sequence": "MAASKPVEAAMAAAAAPASGNGVGSSGGTAAPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGPDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQR",
                "length": 560,
                "header": "tr|R9PXR4-1|R9PXR4_RAT Computationally mapped isoform of Mitochondrial import receptor subunit TOM70  OS=Rattus norvegicus OX=10116 GN=Tomm70 PE=1 SV=1 CANONICAL=Q75Q39-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 43417021,
                "end_pos": 43379016,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000002238",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000002238"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000002238",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000002238"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 104,
            "end_pos": 104,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                },
                {
                    "database": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q75Q39",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q75Q39"
                }
            ],
            "site_lbl": "Ser104"
        },
        {
            "start_pos": 107,
            "end_pos": 107,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                }
            ],
            "site_lbl": "Ser107"
        },
        {
            "start_pos": 112,
            "end_pos": 112,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                }
            ],
            "site_lbl": "Ser112"
        },
        {
            "start_pos": 94,
            "end_pos": 94,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                },
                {
                    "database": "PubMed",
                    "id": "16396499",
                    "url": "https://glygen.org/publication/PubMed/16396499"
                },
                {
                    "database": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q75Q39",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q75Q39"
                }
            ],
            "site_lbl": "Ser94"
        },
        {
            "start_pos": 99,
            "end_pos": 99,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                }
            ],
            "site_lbl": "Ser99"
        }
    ],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Characterization of rat TOM70 as a receptor of the preprotein translocase of the mitochondrial outer membrane.",
            "journal": "J. Cell Sci.",
            "date": "2002",
            "authors": "Suzuki H., Maeda M., Mihara K.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11956321",
                    "url": "https://glygen.org/publication/PubMed/11956321"
                }
            ]
        },
        {
            "title": "Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS.",
            "journal": "Journal of proteome research",
            "date": "2006",
            "authors": "Moser K, White FM",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                },
                {
                    "database": "UniProtKB",
                    "id": "R9PXR4",
                    "url": "https://www.uniprot.org/uniprot/R9PXR4"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q75Q39",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q75Q39"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16396499",
                    "url": "https://glygen.org/publication/PubMed/16396499"
                }
            ]
        },
        {
            "title": "Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism.",
            "journal": "J. Biol. Chem.",
            "date": "2009",
            "authors": "Anandatheerthavarada HK, Sepuri NB, Avadhani NG",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19401463",
                    "url": "https://glygen.org/publication/PubMed/19401463"
                }
            ]
        },
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.",
            "journal": "Nature communications",
            "date": "2012",
            "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q75Q39",
                    "url": "https://www.uniprot.org/uniprot/Q75Q39"
                },
                {
                    "database": "UniProtKB",
                    "id": "R9PXR4",
                    "url": "https://www.uniprot.org/uniprot/R9PXR4"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q75Q39",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q75Q39"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                }
            ]
        },
        {
            "title": "Regulation of protein kinase C-epsilon and its age-dependence.",
            "journal": "Biochemical and biophysical research communications",
            "date": "2017",
            "authors": "Kang C, Qin J, Osei W, Hu K",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_997684",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997684"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27919679",
                    "url": "https://glygen.org/publication/PubMed/27919679"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:304017",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304017",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-168928",
            "name": "DDX58/IFIH1-mediated induction of interferon-alpha/beta",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-168928",
            "resource": "Reactome",
            "description": "DDX58/IFIH1-mediated induction of interferon-alpha/beta"
        },
        {
            "id": "R-RNO-5205685",
            "name": "PINK1-PRKN Mediated Mitophagy",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5205685",
            "resource": "Reactome",
            "description": "PINK1-PRKN Mediated Mitophagy"
        },
        {
            "id": "R-RNO-5689880",
            "name": "Ub-specific processing proteases",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5689880",
            "resource": "Reactome",
            "description": "Ub-specific processing proteases"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "O94826-1",
            "protein_name": "Mitochondrial import receptor subunit TOM70",
            "gene_name": "TOMM70",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
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                "length": 608
            },
            "evidence": [
                {
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                    "database": "MGI"
                },
                {
                    "id": "Q75Q39",
                    "url": "https://omabrowser.org/oma/group/Q75Q39/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P07213-1",
            "protein_name": "Mitochondrial import receptor subunit TOM70",
            "gene_name": "TOM70",
            "tax_id": 559292,
            "organism": "Saccharomyces cerevisiae S288C",
            "sequence": {
                "sequence": "MKSFITRNKTAILATVAATGTAIGAYYYYNQLQQQQQRGKKNTINKDEKKDTKDSQKETEGAKKSTAPSNPPIYPVSSNGEPDFSNKANFTAEEKDKYALALKDKGNQFFRNKKYDDAIKYYNWALELKEDPVFYSNLSACYVSVGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDLSVLSLNGDFNDASIEPMLERNLNKQAMSKLKEKFGDIDTATATPTELSTQPAKERKDKQENLPSVTSMASFFGIFKPELTFANYDESNEADKELMNGLSNLYKRSPESYDKADESFTKAARLFEEQLDKNNEDEKLKEKLAISLEHTGIFKFLKNDPLGAHEDIKKAIELFPRVNSYIYMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKATLLTRNPTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDEAITLFEESADLARTMEEKLQAITFAEAAKVQQRIRSDPVLAKKIQETLAKLREQGLM",
                "length": 617
            },
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                    "id": "Q75Q39",
                    "url": "https://omabrowser.org/oma/group/Q75Q39/",
                    "database": "OMA"
                }
            ],
            "common_name": "Yeast"
        },
        {
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            "protein_name": "Mitochondrial import receptor subunit TOM70",
            "gene_name": "Tomm70",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MAASKPIEAAMAAAAAPGSGNGVGGGGGTAGPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGHHDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEIIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL",
                "length": 611
            },
            "evidence": [
                {
                    "id": "45237173",
                    "url": "http://www.informatics.jax.org/homology/45237173",
                    "database": "MGI"
                },
                {
                    "id": "Q75Q39",
                    "url": "https://omabrowser.org/oma/group/Q75Q39/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 11,
                "go_terms": [
                    {
                        "name": "negative regulation of cell growth involved in cardiac muscle cell development",
                        "id": "GO:0061052",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061052",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to thyroxine",
                        "id": "GO:0097068",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097068",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein insertion into mitochondrial inner membrane",
                        "id": "GO:0045039",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of protein targeting to mitochondrion",
                        "id": "GO:1903955",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903955",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein targeting to mitochondrion",
                        "id": "GO:0006626",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006626",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of defense response to virus by host",
                        "id": "GO:0002230",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230",
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                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of apoptotic process",
                        "id": "GO:0042981",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "activation of innate immune response",
                        "id": "GO:0002218",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to virus",
                        "id": "GO:0098586",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein import into mitochondrial matrix",
                        "id": "GO:0030150",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of interferon-beta production",
                        "id": "GO:0032728",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032728",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "molecular adaptor activity",
                        "id": "GO:0060090",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrion targeting sequence binding",
                        "id": "GO:0030943",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030943",
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                            {
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                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
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                    {
                        "name": "molecular function activator activity",
                        "id": "GO:0140677",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140677",
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                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
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                        "pmid": ""
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            },
            {
                "name": "Cellular Component",
                "total": 3,
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                    {
                        "name": "mitochondrion",
                        "id": "GO:0005739",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739",
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                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrial outer membrane",
                        "id": "GO:0005741",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrial membrane",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966",
                        "evidence": [
                            {
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                                "id": "Q75Q39",
                                "url": "https://www.uniprot.org/uniprot/Q75Q39"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
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    "interactions": [],
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    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
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        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
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}