{
    "uniprot_canonical_ac": "Q6P7B7-1",
    "uniprot_ac": "Q6P7B7",
    "uniprot_id": "ZFY27_RAT",
    "mass": {
        "chemical_mass": 44948.0,
        "monoisotopic_mass": 44948.0
    },
    "refseq": {
        "ac": "NP_954535",
        "name": "protrudin",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535"
    },
    "gene_names": [
        {
            "name": "Zfyve27",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q6P7B7",
            "id": "Q6P7B7"
        },
        {
            "name": "Zfyve27",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006231454",
            "id": "XP_006231454"
        }
    ],
    "protein_names": [
        {
            "name": "Protrudin",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q6P7B7"
        },
        {
            "name": "Zinc finger FYVE domain-containing protein 27",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q6P7B7"
        },
        {
            "name": "protrudin isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006231454",
            "id": "XP_006231454"
        },
        {
            "name": "protrudin",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535",
            "id": "NP_954535"
        },
        {
            "name": "zinc finger FYVE domain-containing protein 27; zinc finger, FYVE domain containing 27",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535",
            "id": "NP_954535"
        }
    ],
    "function": [
        {
            "annotation": "A kinesin 1-protrudin complex mediates AMPA receptor synaptic removal during long-term depression.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_954535",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535"
                },
                {
                    "database": "PubMed",
                    "id": "34348158",
                    "url": "https://glygen.org/publication/PubMed/34348158"
                }
            ]
        },
        {
            "annotation": "Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport (PubMed:17082457). Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections. Acts as an adapter protein that facilitates the interaction of KIF5A with VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 and the ZFYVE27-KIF5A complex contributes to the transport of these proteins in neurons. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a KIF5A/B-dependent manner (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q6P7B7",
                    "url": "https://www.uniprot.org/uniprot/Q6P7B7#function"
                },
                {
                    "database": "PubMed",
                    "id": "17082457",
                    "url": "https://glygen.org/publication/PubMed/17082457"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q3TXX3",
                    "url": "https://www.uniprot.org/uniprot/Q3TXX3#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q5T4F4",
                    "url": "https://www.uniprot.org/uniprot/Q5T4F4#function"
                }
            ]
        },
        {
            "annotation": "Protrudin regulates Rab11-dependent membrane recycling to promote the directional membrane trafficking required for neurite formation [protrudin]",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_954535",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535"
                },
                {
                    "database": "PubMed",
                    "id": "17082457",
                    "url": "https://glygen.org/publication/PubMed/17082457"
                }
            ]
        },
        {
            "annotation": "VAP-A is an important regulator both of the subcellular localization of protrudin and of its ability to stimulate neurite outgrowth.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_954535",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535"
                },
                {
                    "database": "PubMed",
                    "id": "19289470",
                    "url": "https://glygen.org/publication/PubMed/19289470"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0110784",
            "recommended_name": {
                "id": "DOID:0110784",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0110784",
                "name": "hereditary spastic paraplegia 33",
                "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the ZFYVE27 gene on chromosome 10q24."
            },
            "synonyms": [
                {
                    "id": "DOID:0110784",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110784",
                    "name": "SPG33",
                    "description": ""
                },
                {
                    "id": "DOID:0110784",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110784",
                    "name": "autosomal dominant spastic paraplegia 33",
                    "description": ""
                },
                {
                    "id": "MONDO:0012448",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012448",
                    "name": "hereditary spastic paraplegia 33",
                    "description": "Any hereditary spastic paraplegia in which the cause of the disease is a mutation in the ZFYVE27 gene."
                },
                {
                    "id": "MONDO:0012448",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012448",
                    "name": "SPG33",
                    "description": ""
                },
                {
                    "id": "MONDO:0012448",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012448",
                    "name": "ZFYVE27 hereditary spastic paraplegia",
                    "description": ""
                },
                {
                    "id": "MONDO:0012448",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012448",
                    "name": "autosomal dominant spastic paraplegia 33",
                    "description": ""
                },
                {
                    "id": "MONDO:0012448",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012448",
                    "name": "hereditary spastic paraplegia caused by mutation in ZFYVE27",
                    "description": ""
                },
                {
                    "id": "MONDO:0012448",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012448",
                    "name": "hereditary spastic paraplegia type 33",
                    "description": ""
                },
                {
                    "id": "MONDO:0012448",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012448",
                    "name": "spastic paraplegia 33, autosomal dominant",
                    "description": ""
                },
                {
                    "id": "MIM:610244",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/610244",
                    "name": "Spastic paraplegia 33, autosomal dominant",
                    "description": "Spastic paraplegia 33, autosomal dominant"
                }
            ],
            "evidence": [
                {
                    "id": "0110784",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110784"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q6P7B7",
                    "url": "https://www.uniprot.org/uniprot/Q6P7B7"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Zfyve27",
            "url": "https://www.uniprot.org/uniprot/Q6P7B7",
            "locus": {
                "chromosome": "1",
                "start_pos": 241003193,
                "end_pos": 240979842,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000014903",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000014903"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000014903",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000014903",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd15723",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15723",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "309376",
            "url": "https://www.ncbi.nlm.nih.gov/gene/309376",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q6P7B7",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q6P7B7*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR000306",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011011",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013083",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017455",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR042405",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR042405",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:309376",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309376",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "FLLRWKM",
            "url": "https://omabrowser.org/oma/group/FLLRWKM/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "38671at2759",
            "url": "http://www.orthodb.org/?query=38671at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR14543",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14543",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR14543:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14543:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01363",
            "url": "http://pfam.xfam.org/family/PF01363",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q6P7B7",
            "url": "http://purl.obolibrary.org/obo/PR_Q6P7B7",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_954535",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "735177",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=735177",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A140TAG8",
            "url": "https://www.uniprot.org/uniprot/A0A140TAG8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A140TAG8-1",
            "url": "https://www.uniprot.org/uniprot/A0A140TAG8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AJX0",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AJX0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AJX0-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AJX0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AMM0",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AMM0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AMM0-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AMM0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6P7B7",
            "url": "https://www.uniprot.org/uniprot/Q6P7B7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6P7B7-1",
            "url": "https://www.uniprot.org/uniprot/Q6P7B7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MQSSDRDLSGPEASPSVMPEVLSECSPAPTKSTAFDLFNLVLSYKRLEIYLEPLKDAGDGVRYLLRWQMPLCSLLTCLGLNILFLTLNEGAWYSVGALIISVPALLGYLQEVCRAQLPESELMRRKYHSVRQEDLQRVRLSRPEAVAEVKSFLIRLEAFLARLCYTCESAYRVLHWENPVVSSQFYGALLGMVCMLYLLPLCWVLALLNSTLFLGNGEFFRVVSEYRACLQRRMSPKQEECVCEGSALQDAGGRAVVLDSTPAPTPTEDLTPGSVEEAEEAEPDEEFKDAIEEDDEGTPCPAEDELTMQDNGFLSKNEVLRSKVSKLTERLRKRYPTNNFGNCAGCAATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK",
        "length": 404,
        "header": "sp|Q6P7B7-1|ZFY27_RAT Isoform 1 of Protrudin  OS=Rattus norvegicus OX=10116 GN=Zfyve27 PE=1 SV=2 CANONICAL=Q6P7B7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A140TAG8-1",
            "url": "",
            "sequence": {
                "sequence": "MQSSDRDLSGPEASPSVMPEVLSECSPAPTKSTAFDLFNLVLSYKRLEIYLEPLKDAGDGVRYLLRWQMPLCSLLTCLGLNILFLTLNEGAWYSVGALIISVPALLGYLQEVCRAQLPESELMRRKYHSVRQEDLQRVRLSRPEAVAEVKSFLIRLEAFLARLCYTCESAYRVLHWENPVVSSQFYGALLGMVCMLYLLPLCWVLALLNSTLFLGNGEFFRVVSEYRACLQRRMSPKQEECVCEGSALQDAGGRAVVLDSTPAPTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLEDDEGTPCPAEDELTMQDNGFLSKNEVLRSKVSKLTERLRKRYPTNNFGNCAGCAATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK",
                "length": 411,
                "header": "tr|A0A140TAG8-1|ZFY27_RAT Computationally mapped isoform of Protrudin  OS=Rattus norvegicus OX=10116 GN=Zfyve27 PE=1 SV=1 CANONICAL=Q6P7B7-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 240999173,
                "end_pos": 240980745,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000040740.5",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000040740.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000051399.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000051399.4"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AJX0-1",
            "url": "",
            "sequence": {
                "sequence": "MVDARGNVFEDWTCIVSVGNYDYRMQSSDRDLSGPEASPSVMPEVLSECSPAPTKSTAFDLFNLVLSYKRLEIYLEPLKDAGDGVRYLLRWQMPLCSLLTCLGLNILFLTLNEGAWYSVGALIISVPALLGYLQEVCRAQLPESELMRRKYHSVRQEDLQRVRLSRPEAVAEVKSFLIRLEAFLARLCYTCESAYRVLHWENPVVSSQFYGALLGMVCMLYLLPLCWVLALLNSTLFLGNGEFFRVVSEYRACLQRRMSPKQEECVCEGSALQDAGGRAVVLDSTPAPTPTEDLTPGSVEEAEEAEPDEEFKDAIEEDDEGTPCPAEDELTMQDNGFLSKNEVLRSKVSKLTERLRKRYPTNNFGNCAGCAATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK",
                "length": 428,
                "header": "tr|A0A8I6AJX0-1|ZFY27_RAT Computationally mapped isoform of Protrudin  OS=Rattus norvegicus OX=10116 GN=Zfyve27 PE=1 SV=1 CANONICAL=Q6P7B7-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 240999173,
                "end_pos": 240980673,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000114879.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000114879.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000093987.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000093987.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AMM0-1",
            "url": "",
            "sequence": {
                "sequence": "MCDLFVPLLASCPTDLPMCISPWFLCPPPVCTARPLRLEEWLSCDQSSLCCRWQMPLCSLLTCLGLNILFLTLNEGAWYSVGALIISVPALLGYLQEVCRAQLPESELMRRKYHSVRQEDLQRVRLSRPEAVAEVKSFLIRLEAFLARLCYTCESAYRVLHWENPVVSSQFYGALLGMVCMLYLLPLCWVLALLNSTLFLGNGEFFRVVSEYRACLQRRMSPKQEECVCEGSALQDAGGRAVVLDSTPAPTPTEDLTPGSVEEAEEAEPDEEFKDAIEEDDEGTPCPAEDELTMQDNGFLSKNEVLRSKVSKLTERLRKRYPTNNFGNCAGCAATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK",
                "length": 390,
                "header": "tr|A0A8I6AMM0-1|A0A8I6AMM0_RAT Computationally mapped isoform of Protrudin  OS=Rattus norvegicus OX=10116 GN=Zfyve27 PE=4 SV=1 CANONICAL=Q6P7B7-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 240999173,
                "end_pos": 240986015,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000107917.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000107917.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000094645.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000094645.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q6P7B7-1",
            "url": "",
            "sequence": {
                "sequence": "MQSSDRDLSGPEASPSVMPEVLSECSPAPTKSTAFDLFNLVLSYKRLEIYLEPLKDAGDGVRYLLRWQMPLCSLLTCLGLNILFLTLNEGAWYSVGALIISVPALLGYLQEVCRAQLPESELMRRKYHSVRQEDLQRVRLSRPEAVAEVKSFLIRLEAFLARLCYTCESAYRVLHWENPVVSSQFYGALLGMVCMLYLLPLCWVLALLNSTLFLGNGEFFRVVSEYRACLQRRMSPKQEECVCEGSALQDAGGRAVVLDSTPAPTPTEDLTPGSVEEAEEAEPDEEFKDAIEEDDEGTPCPAEDELTMQDNGFLSKNEVLRSKVSKLTERLRKRYPTNNFGNCAGCAATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK",
                "length": 404,
                "header": "sp|Q6P7B7-1|ZFY27_RAT Isoform 1 of Protrudin  OS=Rattus norvegicus OX=10116 GN=Zfyve27 PE=1 SV=2 CANONICAL=Q6P7B7-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 240999173,
                "end_pos": 240980745,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000083287",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000083287"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000074613",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000074613"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Protrudin induces neurite formation by directional membrane trafficking.",
            "journal": "Science",
            "date": "2006",
            "authors": "Shirane M, Nakayama KI",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q6P7B7",
                    "url": "https://www.uniprot.org/uniprot/Q6P7B7"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_954535",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17082457",
                    "url": "https://glygen.org/publication/PubMed/17082457"
                }
            ]
        },
        {
            "title": "Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein.",
            "journal": "The Journal of biological chemistry",
            "date": "2009",
            "authors": "Saita S, Shirane M, Natume T, Iemura S, Nakayama KI",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_954535",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19289470",
                    "url": "https://glygen.org/publication/PubMed/19289470"
                }
            ]
        },
        {
            "title": "A kinesin 1-protrudin complex mediates AMPA receptor synaptic removal during long-term depression.",
            "journal": "Cell reports",
            "date": "2021",
            "authors": "Brachet A, Lario A, Fernandez-Rodrigo A, Heisler FF, Gutierrez Y, Lobo C, Kneussel M, Esteban JA",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_954535",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954535"
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                {
                    "type": "PubMed",
                    "id": "34348158",
                    "url": "https://glygen.org/publication/PubMed/34348158"
                }
            ]
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        {
            "id": "rno:309376",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309376",
            "resource": "KEGG Pathway"
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                "length": 415
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                "length": 411
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            "evidence": [
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                    "id": "45234246",
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                    "database": "MGI"
                }
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            "common_name": "Human"
        }
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                "name": "Cellular Component",
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                            }
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                                "id": "Q6P7B7",
                                "url": "https://www.uniprot.org/uniprot/Q6P7B7"
                            }
                        ],
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                    {
                        "name": "endoplasmic reticulum tubular network",
                        "id": "GO:0071782",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071782",
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                                "database": "UniProtKB",
                                "id": "Q6P7B7",
                                "url": "https://www.uniprot.org/uniprot/Q6P7B7"
                            }
                        ],
                        "pmid": ""
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                    {
                        "name": "cytoplasm",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
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                                "id": "Q6P7B7",
                                "url": "https://www.uniprot.org/uniprot/Q6P7B7"
                            }
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                                "id": "Q6P7B7",
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                    {
                        "name": "membrane",
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                                "id": "Q6P7B7",
                                "url": "https://www.uniprot.org/uniprot/Q6P7B7"
                            }
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                        "pmid": ""
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                                "database": "UniProtKB",
                                "id": "Q6P7B7",
                                "url": "https://www.uniprot.org/uniprot/Q6P7B7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
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            {
                "name": "Biological Process",
                "total": 6,
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                    {
                        "name": "neuron projection development",
                        "id": "GO:0031175",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175",
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                                "id": "Q6P7B7",
                                "url": "https://www.uniprot.org/uniprot/Q6P7B7"
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                        ],
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                    },
                    {
                        "name": "protein localization to plasma membrane",
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