{ "uniprot_canonical_ac": "Q6NWW9-1", "uniprot_ac": "Q6NWW9", "uniprot_id": "FND3B_MOUSE", "mass": { "chemical_mass": 132764.0, "monoisotopic_mass": 132764.0 }, "refseq": { "ac": "NP_775274", "name": "fibronectin type III domain-containing protein 3B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" }, "gene_names": [ { "name": "Fndc3b", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q6NWW9", "id": "Q6NWW9" }, { "name": "1600019O04Rik; Fad104; mKIAA4164", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274", "id": "NP_775274" }, { "name": "Fad104", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q6NWW9", "id": "Q6NWW9" }, { "name": "Fndc3b", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274", "id": "NP_775274" }, { "name": "Kiaa4164", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q6NWW9", "id": "Q6NWW9" }, { "name": "Ns5abp37", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q6NWW9", "id": "Q6NWW9" } ], "protein_names": [ { "name": "Fibronectin type III domain-containing protein 3B", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q6NWW9" }, { "name": "Factor for adipocyte differentiation 104", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q6NWW9" }, { "name": "HCV NS5A-binding protein 37; factor for adipocyte differentiation 104", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274", "id": "NP_775274" }, { "name": "HCV NS5A-binding protein 37", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q6NWW9" }, { "name": "fibronectin type III domain-containing protein 3B", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274", "id": "NP_775274" } ], "function": [ { "annotation": "FNDC3B protects steatosis and ferroptosis via the AMPK pathway in alcoholic fatty liver disease.", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" }, { "database": "PubMed", "id": "36336231", "url": "https://glygen.org/publication/PubMed/36336231" } ] }, { "annotation": "Fad104 is essential for the survival of newborns just after birth and important for cell proliferation, adhesion, spreading and migration.", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" }, { "database": "PubMed", "id": "19138685", "url": "https://glygen.org/publication/PubMed/19138685" } ] }, { "annotation": "Fad104 reciprocally regulates differentiation of adipocytes and osteoblast; functions as a positive regulator in adipocyte differentiation and as a negative regulator in osteoblast differentiation.", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" }, { "database": "PubMed", "id": "20493170", "url": "https://glygen.org/publication/PubMed/20493170" } ] }, { "annotation": "Fad104 suppressed anchorage-independent growth of melanoma cells, and the N-terminal region of FAD104 is essential for inhibiting malignant transformation and STAT3 activity", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" }, { "database": "PubMed", "id": "26948083", "url": "https://glygen.org/publication/PubMed/26948083" } ] }, { "annotation": "Findings highlight a physiological role for circRNAs in cardiac repair and indicate that modulation of circFndc3b expression may represent a potential strategy to promote cardiac function and remodeling after MI. Erratum:[Nat Commun. 2020 May 1;11(1):2234. PMID: 32358483] Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" }, { "database": "PubMed", "id": "31541092", "url": "https://glygen.org/publication/PubMed/31541092" } ] }, { "annotation": "May be positive regulator of adipogenesis.", "evidence": [ { "database": "UniProtKB", "id": "Q6NWW9", "url": "https://www.uniprot.org/uniprot/Q6NWW9#function" } ] }, { "annotation": "MiR-215-5p is a negative regulator of adipocyte differentiation through post-transcriptional regulation of FNDC3B and CTNNBIP1 during early adipogenesis", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" }, { "database": "PubMed", "id": "27521659", "url": "https://glygen.org/publication/PubMed/27521659" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NWW9", "url": "https://www.uniprot.org/uniprot/Q6NWW9" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Fndc3b", "url": "https://www.uniprot.org/uniprot/Q6NWW9", "locus": { "chromosome": "3", "start_pos": 27470311, "end_pos": 27765456, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000039286", "url": "https://www.ensembl.org/id/ENSMUSG00000039286" } ] } } ], "crossref": [ { "id": "ENSMUSG00000039286", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000039286", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "72007", "url": "https://www.ncbi.nlm.nih.gov/gene/72007", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q6NWW9", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q6NWW9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:72007", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:72007", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1919257", "url": "http://www.informatics.jax.org/marker/MGI:1919257", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "DTHFEIR", "url": "https://omabrowser.org/oma/group/DTHFEIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "316463at2759", "url": "http://www.orthodb.org/?query=316463at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "http://pfam.xfam.org/family/PF00041", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q6NWW9", "url": "http://purl.obolibrary.org/obo/PR_Q6NWW9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0A6YX88", "url": "https://www.uniprot.org/uniprot/A0A0A6YX88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0A6YX88-1", "url": "https://www.uniprot.org/uniprot/A0A0A6YX88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0R4J0H8", "url": "https://www.uniprot.org/uniprot/A0A0R4J0H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0R4J0H8-1", "url": "https://www.uniprot.org/uniprot/A0A0R4J0H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q6NWW9", "url": "https://www.uniprot.org/uniprot/Q6NWW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q6NWW9-1", "url": "https://www.uniprot.org/uniprot/Q6NWW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGEAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLPPYLTHHPHFIQNSHTAYYPPVTVPGDMPPQFFPQPHLPPTIYSEPEIIPLYGMSSYVTREDQYSKPPHKKLKDRQIDRQNRLNSPPSTIYKNSCATVYNGYGKGHSGGSSGGGGGGSGGGPGIKKTERRARSSPKSSDSDLQEYELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHGGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAVYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPLAPRLVRAGVTWITLQWSRPEGCSPEEVITYTLDIQEDENDSHFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNMEGKSCPSEVLVCTTSPDRPGPPTRPLIKGPVTSHGFSVKWDAPKDNGGSEIPKYLLEITDGTPEAGQWEVAYSGSATEYVFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSLAPGQCRPPRVLGRPKHKGVHLEWDVPASESGCEVSEYSVEMTEPENVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCRAPRVSFTPDGCVLVGWESPASPGADISEYRLEWGEDEQSLELVYHGPDTCFEMRDLLPAAQYCCRLQAFNPAGAGPYSELVHCQTPASAPDPVSTLCVLEEEPPSAHPDSPSVCLVLNWEEPCNNGSEILAYNIDLGDSCITVGNTTTHVMKNLLPETTYRIRIQAINEIGVGPFSQFIKAKTRPLPPSPPRLECAASGPQSLKLKWGDSNSKTHAAGDMVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAMSEAGEGPYSETYTFSTTKSVPPTLKAPRVTQLEGNSCEIFWETVPPMRGDPVSYVLQVLVGRDSEYKQVYKGEEATFQISGLQSNTDYRFRVCACRRCVDTSQELSGAFSPSAAFMLQQREVMLTGDLGGMEEAKMKGMMPTDEQFAALIVLGFATLSILFAFILQYFLMK", "length": 1207, "header": "sp|Q6NWW9-1|FND3B_MOUSE Isoform 1 of Fibronectin type III domain-containing protein 3B OS=Mus musculus OX=10090 GN=Fndc3b PE=1 SV=1 CANONICAL=Q6NWW9-1" }, "isoforms": [ { "isoform_ac": "A0A0A6YX88-1", "url": "", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGEAAQQVILVQVNPGETFTIRAEDGTLQCIQEYELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHGGLSFPYSYEVAL", "length": 119, "header": "tr|A0A0A6YX88-1|FND3B_MOUSE Computationally mapped isoform of Fibronectin type III domain-containing protein 3B OS=Mus musculus OX=10090 GN=Fndc3b PE=1 SV=1 CANONICAL=Q6NWW9-1" }, "locus": { "chromosome": "3", "start_pos": 27697210, "end_pos": 27555584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000193779.2", "url": "https://www.ensembl.org/id/ENSMUST00000193779.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000141888.2", "url": "https://www.ensembl.org/id/ENSMUSP00000141888.2" } ] } }, { "isoform_ac": "A0A0R4J0H8-1", "url": "", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGEAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLPPYLTHHPHFIQNSHTAYYPPVTVPGDMPPQFFPQPHLPPTIYSEPEIIPLYGMSSYVTREDQYSKPPHKKLKDRQIDRQNRLNSPPSTIYKNSCATVYNGYGKGHSGGSSGGGGGGSGGGPGIKKTERRARSSPKSSDSDLQEYELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHGGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAVYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPLAPRLVRAGVTWITLQWSRPEGCSPEEVITYTLDIQEDENDSHFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNMEGKSCPSEVLVCTTSPDRPGPPTRPLIKGPVTSHGFSVKWDAPKDNGGSEILKYLLEITDGTSEAGQWEVAYSGSATEYVFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSLAPGQCRPPRVLGRPKHKGVHLEWDVPASESGCEVSEYSVEMTEPENVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCRAPRVSFTPDGCVLVGWESPASPGADISEYRLEWGEDEQSLELVYHGPDTCFEMRDLLPAAQYCCRLQAFNPAGAGPYSELVHCQTPASAPDPVSTLCVLEEEPPSAHPDSPSVCLVLNWEEPCNNGSEILAYNIDLGDSCITVGNTTTHVMKNLLPETTYRIRIQAINEIGVGPFSQFIKAKTRPLPPSPPRLECAASGPQSLKLKWGDSNSKTHAAGDMVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAMSEAGEGPYSETYTFSTTKSVPPTLKAPRVTQLEGNSCEIFWETVPPMRGDPVSYVLQVLVGRDSEYKQVYKGEEATFQISGLQSNTDYRFRVCACRRCVDTSQELSGAFSPSAAFMLQQREVMLTGDLGGMEEAKMKGMMPTDEQFAALIVLGFATLSILFAFILQYFLMK", "length": 1207, "header": "tr|A0A0R4J0H8-1|FND3B_MOUSE Computationally mapped isoform of Fibronectin type III domain-containing protein 3B OS=Mus musculus OX=10090 GN=Fndc3b PE=1 SV=1 CANONICAL=Q6NWW9-1" }, "locus": { "chromosome": "3", "start_pos": 27697210, "end_pos": 27473443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000195008.6", "url": "https://www.ensembl.org/id/ENSMUST00000195008.6" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000141620.2", "url": "https://www.ensembl.org/id/ENSMUSP00000141620.2" } ] } }, { "isoform_ac": "Q6NWW9-1", "url": "", "sequence": { "sequence": "MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGEAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLPPYLTHHPHFIQNSHTAYYPPVTVPGDMPPQFFPQPHLPPTIYSEPEIIPLYGMSSYVTREDQYSKPPHKKLKDRQIDRQNRLNSPPSTIYKNSCATVYNGYGKGHSGGSSGGGGGGSGGGPGIKKTERRARSSPKSSDSDLQEYELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHGGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAVYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSSLTLQWKAPIDNGSKITSYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPLAPRLVRAGVTWITLQWSRPEGCSPEEVITYTLDIQEDENDSHFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNMEGKSCPSEVLVCTTSPDRPGPPTRPLIKGPVTSHGFSVKWDAPKDNGGSEIPKYLLEITDGTPEAGQWEVAYSGSATEYVFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSLAPGQCRPPRVLGRPKHKGVHLEWDVPASESGCEVSEYSVEMTEPENVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCRAPRVSFTPDGCVLVGWESPASPGADISEYRLEWGEDEQSLELVYHGPDTCFEMRDLLPAAQYCCRLQAFNPAGAGPYSELVHCQTPASAPDPVSTLCVLEEEPPSAHPDSPSVCLVLNWEEPCNNGSEILAYNIDLGDSCITVGNTTTHVMKNLLPETTYRIRIQAINEIGVGPFSQFIKAKTRPLPPSPPRLECAASGPQSLKLKWGDSNSKTHAAGDMVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAMSEAGEGPYSETYTFSTTKSVPPTLKAPRVTQLEGNSCEIFWETVPPMRGDPVSYVLQVLVGRDSEYKQVYKGEEATFQISGLQSNTDYRFRVCACRRCVDTSQELSGAFSPSAAFMLQQREVMLTGDLGGMEEAKMKGMMPTDEQFAALIVLGFATLSILFAFILQYFLMK", "length": 1207, "header": "sp|Q6NWW9-1|FND3B_MOUSE Isoform 1 of Fibronectin type III domain-containing protein 3B OS=Mus musculus OX=10090 GN=Fndc3b PE=1 SV=1 CANONICAL=Q6NWW9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 208, "end_pos": 208, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NWW9", "url": "https://www.uniprot.org/uniprot/Q6NWW9" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q6NWW9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NWW9" } ], "site_lbl": "Ser208" }, { "start_pos": 261, "end_pos": 261, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NWW9", "url": "https://www.uniprot.org/uniprot/Q6NWW9" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "phospho.ELM", "id": "Q6NWW9", "url": "http://phospho.elm.eu.org/byAccession/Q6NWW9.html" }, { "database": "iPTMnet", "id": "Q6NWW9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NWW9" } ], "site_lbl": "Ser261" }, { "start_pos": 396, "end_pos": 396, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NWW9", "url": "https://www.uniprot.org/uniprot/Q6NWW9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6NWW9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NWW9" } ], "site_lbl": "Ser396" } ], "glycation": [], "keywords": [], "publication": [ { "title": "FNDC3A is required for adhesion between spermatids and Sertoli cells.", "journal": "Dev. Biol.", "date": "2006", "authors": "Obholz KL, Akopyan A, Waymire KG, MacGregor GR", "evidence": [ { "database": "UniProtKB", "id": "Q6NWW9", "url": "https://www.uniprot.org/uniprot/Q6NWW9" } ], "reference": [ { "type": "PubMed", "id": "16904100", "url": "https://glygen.org/publication/PubMed/16904100" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NWW9", "url": "https://www.uniprot.org/uniprot/Q6NWW9" }, { "database": "UniProtKB", "id": "A0A0R4J0H8", "url": "https://www.uniprot.org/uniprot/A0A0R4J0H8" }, { "database": "iPTMnet", "id": "Q6NWW9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NWW9" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "Disruption of the novel gene fad104 causes rapid postnatal death and attenuation of cell proliferation, adhesion, spreading and migration.", "journal": "Experimental cell research", "date": "2009", "authors": "Nishizuka M, Kishimoto K, Kato A, Ikawa M, Okabe M, Sato R, Niida H, Nakanishi M, Osada S, Imagawa M", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" } ], "reference": [ { "type": "PubMed", "id": "19138685", "url": "https://glygen.org/publication/PubMed/19138685" } ] }, { "title": "Fad104, a positive regulator of adipogenesis, negatively regulates osteoblast differentiation.", "journal": "Biochemical and biophysical research communications", "date": "2010", "authors": "Kishimoto K, Kato A, Osada S, Nishizuka M, Imagawa M", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" } ], "reference": [ { "type": "PubMed", "id": "20493170", "url": "https://glygen.org/publication/PubMed/20493170" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NWW9", "url": "https://www.uniprot.org/uniprot/Q6NWW9" }, { "database": "iPTMnet", "id": "Q6NWW9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NWW9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "FAD104, a Regulator of Adipogenesis and Osteogenesis, Interacts with the C-Terminal Region of STAT3 and Represses Malignant Transformation of Melanoma Cells.", "journal": "Biological & pharmaceutical bulletin", "date": "2016", "authors": "Katoh D, Nishizuka M, Osada S, Imagawa M", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" } ], "reference": [ { "type": "PubMed", "id": "26948083", "url": "https://glygen.org/publication/PubMed/26948083" } ] }, { "title": "MicroRNA-215 impairs adipocyte differentiation and co-represses FNDC3B and CTNNBIP1.", "journal": "The international journal of biochemistry & cell biology", "date": "2016", "authors": "Peng Y, Li H, Li X, Yu S, Xiang H, Peng J, Jiang S", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" } ], "reference": [ { "type": "PubMed", "id": "27521659", "url": "https://glygen.org/publication/PubMed/27521659" } ] }, { "title": "Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis.", "journal": "Nature communications", "date": "2019", "authors": "Garikipati VNS, Verma SK, Cheng Z, Liang D, Truongcao MM, Cimini M, Yue Y, Huang G, Wang C, Benedict C, Tang Y, Mallaredy V, Ibetti J, Grisanti L, Schumacher SM, Gao E, Rajan S, Wilusz JE, Goukassian D, Houser SR, Koch WJ, Kishore R", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" } ], "reference": [ { "type": "PubMed", "id": "31541092", "url": "https://glygen.org/publication/PubMed/31541092" } ] }, { "title": "FNDC3B protects steatosis and ferroptosis via the AMPK pathway in alcoholic fatty liver disease.", "journal": "Free radical biology & medicine", "date": "2022-11-20", "authors": "You Yajing, Liu Chenxi, Liu Tiantian, Tian Miaomiao, Wu Nijin, Yu Zhen, Zhao Fenglin, Qi Jianni, Zhu Qiang", "evidence": [ { "database": "RefSeq", "id": "NP_775274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775274" } ], "reference": [ { "type": "PubMed", "id": "36336231", "url": "https://glygen.org/publication/PubMed/36336231" } ] } ], "pathway": [ { "id": "mmu:72007", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:72007", "resource": "KEGG Pathway" } ], "orthologs": 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