{ "uniprot_canonical_ac": "Q6MG64-1", "uniprot_ac": "Q6MG64", "uniprot_id": "VWA7_RAT", "mass": { "chemical_mass": 96045.0, "monoisotopic_mass": 96045.0 }, "refseq": { "ac": "NP_997664", "name": "von Willebrand factor A domain-containing protein 7 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997664" }, "gene_names": [ { "name": "Vwa7", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q6MG64", "id": "Q6MG64" }, { "name": "C6orf27; G7c; NG37", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997664", "id": "NP_997664" }, { "name": "G7c", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q6MG64", "id": "Q6MG64" }, { "name": "Vwa7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997664", "id": "NP_997664" } ], "protein_names": [ { "name": "von Willebrand factor A domain-containing protein 7", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q6MG64" }, { "name": "Protein G7c", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q6MG64" }, { "name": "protein G7c; von Willebrand factor A domain-containing protein 7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997664", "id": "NP_997664" }, { "name": "von Willebrand factor A domain-containing protein 7 precursor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997664", "id": "NP_997664" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q6MG64", "url": "https://www.uniprot.org/uniprot/Q6MG64" } ], "common_name": "Rat" } ], "gene": [ { "name": "Vwa7", "url": "https://www.uniprot.org/uniprot/Q6MG64", "locus": { "chromosome": "20", "start_pos": 3794991, "end_pos": 3805525, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000000860", "url": "https://www.ensembl.org/id/ENSRNOG00000000860" } ] } } ], "crossref": [ { "id": "ENSRNOG00000000860", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000000860", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "309611", "url": "https://www.ncbi.nlm.nih.gov/gene/309611", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:309611", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309611", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEPIHYV", "url": "https://omabrowser.org/oma/group/MEPIHYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "4136946at2759", "url": "http://www.orthodb.org/?query=4136946at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14905:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14905:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR_Q6MG64", "url": "http://purl.obolibrary.org/obo/PR_Q6MG64", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_997664", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997664", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1303137", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1303137", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "Q6MG64", "url": "https://www.uniprot.org/uniprot/Q6MG64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q6MG64-1", "url": "https://www.uniprot.org/uniprot/Q6MG64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPVEVPLSQLGPPVLLLQLLLPPTSAFFPNIWSLLAAPGSITHQDLTEEAALNVTLELFLEQPPPGRPHLHLEDYRGRTLLADDIFAAYFGSGFSSRRFRAALGEVSRANAAQDFLPASKSNPDLHFDAERLVQGRTRLEGALRETLVAARALEYTLARQRLGAALHALQDFYSHSNWVELGERQPHPHLLWPRRELWSLAQVGDPTCSDCEGLSCPGNMMNLTMLTSGYFGTNPPKPPGKCSHGGRFDQSSSQPPRGGINKDSTSPSFSPHHRLHLQAAEVALLASIEALSLLRSRLGTRGFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARRIVEQRQGSPMEPVSYILVPFHDPGFGPVFTTSDPDSFWQKLTEIHALGGGDEPEMCLSALELALLHTPPLSDIFVFTDASPKDAFLTNRVESLTRERRCRVTFLVTEDPSRAQGRGRREALSPSRFEPYEAIALASGGEVIFTKDQHIRDVAAVVGESMAGLVTLPLEPPIFTPGEPCVFAVDSLLSKVTVRMHGDISGFWIKSPAGLSQGPEEGIGPLGHTRRFGQFWTVTMTDPPQTGSWEIQVAAEGTPRVRVQAQTSLDFLFHFGISAEDGPHPGLYPLTQPVAGLQTQLLVEVTGLVSRQKLGDGQPQFSHAVLRRVSEGTHLGRVSLEPVGPPERGLLAASLPPTLLSVSVPFSLELVGQDVGGQCLRRSAPQPCSVAPVLLELSGPPDFLTPGSKAPLSLRVASFSGPQDVDLRSSVNPSFSLTSNLSRARLGLNESAWGCLWLEVPDSAAPDTVVTVTVTVTAVGQGASQVPPTHAFLQLLVLAQSSKDQLEDPTHSAAPVLPPTTPALLPSTLVTRGRAGRGTTGKTWWGTVGGVLFLLGCTSW", "length": 892, "header": "sp|Q6MG64-1|VWA7_RAT Isoform 1 of von Willebrand factor A domain-containing protein 7 OS=Rattus norvegicus OX=10116 GN=Vwa7 PE=3 SV=1 CANONICAL=Q6MG64-1" }, "isoforms": [ { "isoform_ac": "Q6MG64-1", "url": "", "sequence": { "sequence": "MLPVEVPLSQLGPPVLLLQLLLPPTSAFFPNIWSLLAAPGSITHQDLTEEAALNVTLELFLEQPPPGRPHLHLEDYRGRTLLADDIFAAYFGSGFSSRRFRAALGEVSRANAAQDFLPASKSNPDLHFDAERLVQGRTRLEGALRETLVAARALEYTLARQRLGAALHALQDFYSHSNWVELGERQPHPHLLWPRRELWSLAQVGDPTCSDCEGLSCPGNMMNLTMLTSGYFGTNPPKPPGKCSHGGRFDQSSSQPPRGGINKDSTSPSFSPHHRLHLQAAEVALLASIEALSLLRSRLGTRGFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARRIVEQRQGSPMEPVSYILVPFHDPGFGPVFTTSDPDSFWQKLTEIHALGGGDEPEMCLSALELALLHTPPLSDIFVFTDASPKDAFLTNRVESLTRERRCRVTFLVTEDPSRAQGRGRREALSPSRFEPYEAIALASGGEVIFTKDQHIRDVAAVVGESMAGLVTLPLEPPIFTPGEPCVFAVDSLLSKVTVRMHGDISGFWIKSPAGLSQGPEEGIGPLGHTRRFGQFWTVTMTDPPQTGSWEIQVAAEGTPRVRVQAQTSLDFLFHFGISAEDGPHPGLYPLTQPVAGLQTQLLVEVTGLVSRQKLGDGQPQFSHAVLRRVSEGTHLGRVSLEPVGPPERGLLAASLPPTLLSVSVPFSLELVGQDVGGQCLRRSAPQPCSVAPVLLELSGPPDFLTPGSKAPLSLRVASFSGPQDVDLRSSVNPSFSLTSNLSRARLGLNESAWGCLWLEVPDSAAPDTVVTVTVTVTAVGQGASQVPPTHAFLQLLVLAQSSKDQLEDPTHSAAPVLPPTTPALLPSTLVTRGRAGRGTTGKTWWGTVGGVLFLLGCTSW", "length": 892, "header": "sp|Q6MG64-1|VWA7_RAT Isoform 1 of von Willebrand factor A domain-containing protein 7 OS=Rattus norvegicus OX=10116 GN=Vwa7 PE=3 SV=1 CANONICAL=Q6MG64-1" }, "locus": { "chromosome": "20", "start_pos": 3805034, "end_pos": 3796460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000001153", "url": "https://www.ensembl.org/id/ENSRNOT00000001153" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000001153", "url": "https://www.ensembl.org/id/ENSRNOP00000001153" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 54, "start_aa": "Asn", "end_pos": 54, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn54", "evidence": [ { "id": "Q6MG64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6MG64#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genomic sequence and comparative analysis of the rat major histocompatibility complex.", "journal": "Genome Res.", "date": "2004", "authors": "Hurt P, Walter L, Sudbrak R, Klages S, Muller I, Shiina T, Inoko H, Lehrach H, Gunther E, Reinhardt R, Himmelbauer H", "evidence": [ { "database": "UniProtKB", "id": "Q6MG64", "url": "https://www.uniprot.org/uniprot/Q6MG64" } ], "reference": [ { "type": "PubMed", "id": "15060004", "url": "https://glygen.org/publication/PubMed/15060004" } ] } ], "pathway": [ { "id": "rno:309611", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309611", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9JHA8-1", "protein_name": "von Willebrand factor A domain-containing protein 7", "gene_name": "Vwa7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVEVPLSHLGPPILLLLQLLLPPTSAFFPNIWSLLAAPGSVTHQDLTEEAALNVTLVLFLEQPHPGRPRLHVEDYRGRTLLADDIFAAYFGPGFSSRRFRAALGEVSRANAAQDFLPAFKSNPDLHFDAERLVQGRTRLVGALRETLVAARALEYTLARQRLGAALHALQDFYSHSNWVELGERQPHPHLLWPRQELWSLAQVGDPTCSDCEGLSCPGNMLDSTLLTSGYFGMHPPKPPGKCSHGGHFDQSSSQPPRGGINKDSTSPSFSPHHKLHLQAAEVALLASIEAFSLLRSRLGDKAFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARRIVEQRQGSPMEPVFYILVPFHDPGFGPVFTTSDPDSFWQKLNEIHALGGGDEPEMCLSALELALLHTPPLSDIFVFTDASPKDALLTNRVESLTRERRCRVTFLVTEDPSRTGGRRRREALSPLRFEPYEAIARASGGEVIFTKDQYIQDVAAIVGESMAGLVTLPLDPPVFTPGEPCVFSVDSLLWQVTVRMHGDISSFWIKSPAGVSQGPEEGIGPLGHTRRFGQFWTVTMTDPPRTGTWEIQVAAAGTPRVRVQAQTSLDFLFHFGISVEDGPHPGLYPLTQPVAGLQTQLLVEVTGLTSRQKLVGGQPQFSHVVLRRVPEGTQLGRVSLEPVGPPVRGLLAASLPPTLLSVSSPFSLELVGQGGGGESLRRTAPQPCSVAPVLLELSGPPDFLTPGSKAPLSLHIVSFSGPQDLDLRTSVNPSFSLTSNLSRARLGLNESAWGRLWLEVPDSAAPDSVVMVTVTAAGQGASQVPPTHAFLRLLVLAQSSKDQLDGPAHSAAPVLPPVSPALLPSTLVTQGRAGGGMAGKAWWGTVGGVLFLLGCTSW", "length": 891 }, "evidence": [ { "id": "45228345", "url": "http://www.informatics.jax.org/homology/45228345", "database": "MGI" }, { "id": "Q6MG64", "url": "https://omabrowser.org/oma/group/Q6MG64/", "database": "OMA" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y334-1", "protein_name": "von Willebrand factor A domain-containing protein 7", "gene_name": "VWA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPTEVPQSHPGPSALLLLQLLLPPTSAFFPNIWSLLAAPGSITHQDLTEEAALNVTLQLFLEQPPPGRPPLRLEDFLGRTLLADDLFAAYFGPGSSRRFRAALGEVSRANAAQDFLPTSRNDPDLHFDAERLGQGRARLVGALRETVVAARALDHTLARQRLGAALHALQDFYSHSNWVELGEQQPHPHLLWPRQELQNLAQVADPTCSDCEELSCPRNWLGFTLLTSGYFGTHPPKPPGKCSHGGHFDRSSSQPPRGGINKDSTSPGFSPHHMLHLQAAKLALLASIQAFSLLRSRLGDRDFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARHLVEQRRGSPMEPVHYVLVPFHDPGFGPVFTTSDPDSFWQQLNEIHALGGGDEPEMCLSALQLALLHTPPLSDIFVFTDASPKDAFLTNQVESLTQERRCRVTFLVTEDTSRVQGRARREILSPLRFEPYKAVALASGGEVIFTKDQHIRDVAAIVGESMAALVTLPLDPPVVVPGQPLVFSVDGLLQKITVRIHGDISSFWIKNPAGVSQGQEEGGGPLGHTRRFGQFWMVTMDDPPQTGTWEIQVTAEDTPGVRVQAQTSLDFLFHFGIPMEDGPHPGLYPLTQPVAGLQTQLLVEVTGLGSRANPGDPQPHFSHVILRGVPEGAELGQVPLEPVGPPERGLLAASLSPTLLSTPRPFSLELIGQDAAGRRLHRAAPQPSTVVPVLLELSGPSGFLAPGSKVPLSLRIASFSGPQDLDLRTFVNPSFSLTSNLSRAHLELNESAWGRLWLEVPDSAAPDSVVMVTVTAGGREANPVPPTHAFLRLLVSAPAPQDRHTTPTGSSDPILTTATPAFSPFTLVTQGRAGAGLAAGSPWWGTVGGVLLLLGLASW", "length": 891 }, "evidence": [ { "id": "45228345", "url": "http://www.informatics.jax.org/homology/45228345", "database": "MGI" }, { "id": "Q6MG64", "url": "https://omabrowser.org/oma/group/Q6MG64/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q6MG64", "url": "https://www.uniprot.org/uniprot/Q6MG64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }