{
    "uniprot_canonical_ac": "Q6AYC6-1",
    "uniprot_ac": "Q6AYC6",
    "uniprot_id": "Q6AYC6_RAT",
    "mass": {
        "chemical_mass": 39133.0,
        "monoisotopic_mass": 39133.0
    },
    "refseq": {
        "ac": "NP_001013136",
        "name": "ABI gene family member 3",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013136"
    },
    "gene_names": [
        {
            "name": "Abi3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q6AYC6",
            "id": "Q6AYC6"
        },
        {
            "name": "Abi3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013136",
            "id": "NP_001013136"
        }
    ],
    "protein_names": [
        {
            "name": "ABI family, member 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q6AYC6"
        },
        {
            "name": "ABI gene family member 3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013136",
            "id": "NP_001013136"
        },
        {
            "name": "ABI gene family, member 3; NESH protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013136",
            "id": "NP_001013136"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q6AYC6",
                    "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Abi3",
            "url": "https://www.uniprot.org/uniprot/Q6AYC6",
            "locus": {
                "chromosome": "10",
                "start_pos": 80769822,
                "end_pos": 80780816,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000005575",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000005575"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000005575",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000005575",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd11826",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11826",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "303476",
            "url": "https://www.ncbi.nlm.nih.gov/gene/303476",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001452",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR012849",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012849",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR028455",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028455",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR028457",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028457",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036028",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:303476",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303476",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "YVTRRYS",
            "url": "https://omabrowser.org/oma/group/YVTRRYS/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3028771at2759",
            "url": "http://www.orthodb.org/?query=3028771at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10460",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10460",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10460:SF7",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10460:SF7",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07815",
            "url": "http://pfam.xfam.org/family/PF07815",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF14604",
            "url": "http://pfam.xfam.org/family/PF14604",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001013136",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013136",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1311794",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1311794",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8I5ZSD9",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZSD9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZSD9-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZSD9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6AYC6",
            "url": "https://www.uniprot.org/uniprot/Q6AYC6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6AYC6-1",
            "url": "https://www.uniprot.org/uniprot/Q6AYC6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAELQQLQQLQEFDIPTGREALRGNHSALLRVANYCEDNYLQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEAKMSTLGQMVNMHLEKVARREIGTLATVVRLPPSQKVIPPESLPPLTPYCRKPLNFACLDDVGHGVKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVQLPAVPDGKLSAASSVSSLASAGSAEGASGIPQSKGQVAPATPPPPPIAPVTPPPPPLPAEIFLLPPPMEESQPPPETELPLPPPPALQGDELGLLPPPPPGFGPDEPSWVPAAYLEKVVTLYPYTRQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC",
        "length": 367,
        "header": "tr|Q6AYC6-1|Q6AYC6_RAT Isoform 1 of ABI family, member 3  OS=Rattus norvegicus OX=10116 GN=Abi3 PE=1 SV=1 CANONICAL=Q6AYC6-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I5ZSD9-1",
            "url": "",
            "sequence": {
                "sequence": "MAELQQLQQLQEFDIPTGREALRGNHSALLRVANYCEDNYLQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEAKMSTLGQMVNMHLEKVARREIGTLATVVRLPPSQKVIPPESLPPLTPYCRKPLNFACLDDVGHGVKDLSTQLSRTGTLSRKSIKAPATPASATPAQPLVYMVWSFSSAEGASGIPQSKGQVAPATPPPPPIAPVTPPPPPLPAEIFLLPPPMEESQPPPETELPLPPPPALQGDELGLLPPPPPGFGPDEPSWVPAAYLEKVVTLYPYTRQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC",
                "length": 346,
                "header": "tr|A0A8I5ZSD9-1|A0A8I5ZSD9_RAT Computationally mapped isoform of ABI family, member 3  OS=Rattus norvegicus OX=10116 GN=Abi3 PE=1 SV=1 CANONICAL=Q6AYC6-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 80780532,
                "end_pos": 80770120,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000119228.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000119228.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000081789.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000081789.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q6AYC6-1",
            "url": "",
            "sequence": {
                "sequence": "MAELQQLQQLQEFDIPTGREALRGNHSALLRVANYCEDNYLQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEAKMSTLGQMVNMHLEKVARREIGTLATVVRLPPSQKVIPPESLPPLTPYCRKPLNFACLDDVGHGVKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVQLPAVPDGKLSAASSVSSLASAGSAEGASGIPQSKGQVAPATPPPPPIAPVTPPPPPLPAEIFLLPPPMEESQPPPETELPLPPPPALQGDELGLLPPPPPGFGPDEPSWVPAAYLEKVVTLYPYTRQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC",
                "length": 367,
                "header": "tr|Q6AYC6-1|Q6AYC6_RAT Isoform 1 of ABI family, member 3  OS=Rattus norvegicus OX=10116 GN=Abi3 PE=1 SV=1 CANONICAL=Q6AYC6-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 80780532,
                "end_pos": 80770120,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000007897.4",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000007897.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000007897.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000007897.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.",
            "journal": "Nat. Commun.",
            "date": "2012",
            "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q6AYC6",
                    "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:303476",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303476",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8BYZ1-1",
            "protein_name": "ABI gene family member 3",
            "gene_name": "Abi3",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MAELQQLQQLQEFDIPTGREALRGNHSALLRVANYCEDNYLQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEAKMSTLGQMVNMHMEKVARREIGTLATVVRLPSNQKVIPPESLPSLTPYHRKPLNFACLDDIGHGVKDLSTQLSRTGTLSRKSIKAPATPVSATLGRPPRIPEPVQLPAVPDGKLSAASSASSLASAGSAEGASGIPQSKGQVAPATPPPPPVAPVTPPPPPLSAEVFLPPPPLEVSQPPLEAELPLPPPPALEGDELGLLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTRQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC",
                "length": 367
            },
            "evidence": [
                {
                    "id": "45238576",
                    "url": "http://www.informatics.jax.org/homology/45238576",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9P2A4-1",
            "protein_name": "ABI gene family member 3",
            "gene_name": "ABI3",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSAFSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC",
                "length": 366
            },
            "evidence": [
                {
                    "id": "45238576",
                    "url": "http://www.informatics.jax.org/homology/45238576",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "SH3 domain binding",
                        "id": "GO:0017124",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AYC6",
                                "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "identical protein binding",
                        "id": "GO:0042802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AYC6",
                                "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "lamellipodium",
                        "id": "GO:0030027",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AYC6",
                                "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "SCAR complex",
                        "id": "GO:0031209",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031209",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AYC6",
                                "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 5,
                "go_terms": [
                    {
                        "name": "regulation of cell migration",
                        "id": "GO:0030334",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AYC6",
                                "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of protein localization to plasma membrane",
                        "id": "GO:1903077",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903077",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AYC6",
                                "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of cellular senescence",
                        "id": "GO:2000774",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000774",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AYC6",
                                "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "defense response to tumor cell",
                        "id": "GO:0002357",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002357",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AYC6",
                                "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of lamellipodium assembly",
                        "id": "GO:0010593",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010593",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AYC6",
                                "url": "https://www.uniprot.org/uniprot/Q6AYC6"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 25,
            "end_pos": 27,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}