{
    "uniprot_canonical_ac": "Q6AY62-1",
    "uniprot_ac": "Q6AY62",
    "uniprot_id": "NEUFC_RAT",
    "mass": {
        "chemical_mass": 29065.0,
        "monoisotopic_mass": 29065.0
    },
    "refseq": {
        "ac": "NP_001007672",
        "name": "neuferricin precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007672"
    },
    "gene_names": [
        {
            "name": "Cyb5d2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q6AY62",
            "id": "Q6AY62"
        },
        {
            "name": "Cyb5d2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007672",
            "id": "NP_001007672"
        }
    ],
    "protein_names": [
        {
            "name": "Neuferricin",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q6AY62"
        },
        {
            "name": "Cytochrome b5 domain-containing protein 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q6AY62"
        },
        {
            "name": "cytochrome b5 domain-containing protein 2; neuferricin",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007672",
            "id": "NP_001007672"
        },
        {
            "name": "neuferricin isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006246792",
            "id": "XP_006246792"
        },
        {
            "name": "neuferricin precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007672",
            "id": "NP_001007672"
        }
    ],
    "function": [
        {
            "annotation": "Heme-binding protein which promotes neuronal but not astrocyte differentiation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q6AY62",
                    "url": "https://www.uniprot.org/uniprot/Q6AY62#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q6AY62",
                    "url": "https://www.uniprot.org/uniprot/Q6AY62"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Cyb5d2",
            "url": "https://www.uniprot.org/uniprot/Q6AY62",
            "locus": {
                "chromosome": "10",
                "start_pos": 57396765,
                "end_pos": 57413715,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000024553",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000024553"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000024553",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000024553",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "303293",
            "url": "https://www.ncbi.nlm.nih.gov/gene/303293",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001199",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001199",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036400",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036400",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:303293",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303293",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "GHKHYGP",
            "url": "https://omabrowser.org/oma/group/GHKHYGP/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2872279at2759",
            "url": "http://www.orthodb.org/?query=2872279at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10281",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10281",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10281:SF4",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10281:SF4",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00173",
            "url": "http://pfam.xfam.org/family/PF00173",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q6AY62",
            "url": "http://purl.obolibrary.org/obo/PR_Q6AY62",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001007672",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007672",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1359124",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1359124",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8I6GFL4",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GFL4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6GFL4-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GFL4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6AY62",
            "url": "https://www.uniprot.org/uniprot/Q6AY62",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6AY62-1",
            "url": "https://www.uniprot.org/uniprot/Q6AY62-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MLRICGLGVVLSLAVAAAAVLAVWLMDWWGSHPSIRLFVPEELARYRGGPGDPGLYLALLGRVYDVSSGRKHYEPGAHYSGFAGRDASRAFVTGDYSEAGLVDDVNGLSSSEILTLHNWLSFYEKNYVFVGRLIGRFYGKDGLPTSELTQVEAMVTKGMEANEQEQREKQRFPPCNAEWSSAKGSRLWCSQKSGGVHRDWIGVPRKLYKPGAKEPHCVCVRTTGPPSDQQDNPRHSNRGDLDNPNLEEYTGCPPLAVTCFFPL",
        "length": 263,
        "header": "sp|Q6AY62-1|NEUFC_RAT Isoform 1 of Neuferricin  OS=Rattus norvegicus OX=10116 GN=Cyb5d2 PE=2 SV=1 CANONICAL=Q6AY62-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I6GFL4-1",
            "url": "",
            "sequence": {
                "sequence": "MGSPSWVLGGVAAAAAASQPRPVNLRQLLAGGDGVETTAAAATSGFLAVELGLMSQRSRQADSICSRQLGRDASRAFVTGDYSEAGLVDDVNGLSSSEILTLHNWLSFYEKNYVFVGRLIGRFYGKDGLPTSELTQVEAMVTKGMEANEQEQREKQRFPPCNAEWSSAKGSRLWCSQKSGGVHRDWIGVPRKLYKPGAKEPHCVCVRTTGPPSDQQDNPRHSNRGDLDNPNLEEYTGCPPLAVTCFFPL",
                "length": 249,
                "header": "tr|A0A8I6GFL4-1|A0A8I6GFL4_RAT Computationally mapped isoform of Cytochrome b5 domain containing 2  OS=Rattus norvegicus OX=10116 GN=Cyb5d2 PE=4 SV=1 CANONICAL=Q6AY62-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 57413300,
                "end_pos": 57397224,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000097276.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000097276.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000087907.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000087907.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q6AY62-1",
            "url": "",
            "sequence": {
                "sequence": "MLRICGLGVVLSLAVAAAAVLAVWLMDWWGSHPSIRLFVPEELARYRGGPGDPGLYLALLGRVYDVSSGRKHYEPGAHYSGFAGRDASRAFVTGDYSEAGLVDDVNGLSSSEILTLHNWLSFYEKNYVFVGRLIGRFYGKDGLPTSELTQVEAMVTKGMEANEQEQREKQRFPPCNAEWSSAKGSRLWCSQKSGGVHRDWIGVPRKLYKPGAKEPHCVCVRTTGPPSDQQDNPRHSNRGDLDNPNLEEYTGCPPLAVTCFFPL",
                "length": 263,
                "header": "sp|Q6AY62-1|NEUFC_RAT Isoform 1 of Neuferricin  OS=Rattus norvegicus OX=10116 GN=Cyb5d2 PE=2 SV=1 CANONICAL=Q6AY62-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 57412792,
                "end_pos": 57397224,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000036942",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000036942"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000038452",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000038452"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:303293",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303293",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q5SSH8-1",
            "protein_name": "Neuferricin",
            "gene_name": "Cyb5d2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MLRICGLGVVLSLAVAAVAVMAVWLMDWWGPRPGIRLFLPEELARYRGGPGDPGLYLALLGRVYDVSSGRRHYEPGAHYSGFAGRDASRAFVTGDYSEAGLVDDINGLSSSEILTLHNWLSFYEKNYVFVGRLVGRFYRKDGLPTSELTQVEAMVTKGMEANEQEQREKQKFPPCNSEWSSAKGSRLWCSQKSGGVHRDWIGVPRKLYKPGAKEPHCVCVRTTGPPSDQQDNPRHSNHGDLDNPNLEEYTGCPPLATTCSFPL",
                "length": 263
            },
            "evidence": [
                {
                    "id": "45236931",
                    "url": "http://www.informatics.jax.org/homology/45236931",
                    "database": "MGI"
                },
                {
                    "id": "Q6AY62",
                    "url": "https://omabrowser.org/oma/group/Q6AY62/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q8WUJ1-1",
            "protein_name": "Neuferricin",
            "gene_name": "CYB5D2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MLRCGGRGLLLGLAVAAAAVMAARLMGWWGPRAGFRLFIPEELSRYRGGPGDPGLYLALLGRVYDVSSGRRHYEPGSHYSGFAGRDASRAFVTGDCSEAGLVDDVSDLSAAEMLTLHNWLSFYEKNYVCVGRVTGRFYGEDGLPTPALTQVEAAITRGLEANKLQLQEKQTFPPCNAEWSSARGSRLWCSQKSGGVSRDWIGVPRKLYKPGAKEPRCVCVRTTGPPSGQMPDNPPHRNRGDLDHPNLAEYTGCPPLAITCSFPL",
                "length": 264
            },
            "evidence": [
                {
                    "id": "45236931",
                    "url": "http://www.informatics.jax.org/homology/45236931",
                    "database": "MGI"
                },
                {
                    "id": "Q6AY62",
                    "url": "https://omabrowser.org/oma/group/Q6AY62/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9W376-1",
            "protein_name": "Neuferricin homolog",
            "gene_name": "",
            "tax_id": 7227,
            "organism": "Drosophila melanogaster",
            "sequence": {
                "sequence": "MFGLLRHLFKFQFLFVVAAVLGGIYHTEIRQFLRRQTDNYLDQAGQDASIPLAFQAGDDIGTLFTPAELAKFNGEEEGRPLYLALLGSVFDVSRGIKHYGSGCSYNFFVGRDASVSFISGDFETYDPETADDVLTLKPDDLIGLAGWRDFYQKDYVYKGRVIGRFYDEKGALTTYHHKFLELLEQARDAKRQVEELRARYPGCNIEWSEERGTRVWCTTTSGDGKERSWIGYPRKLYSRGNKSFQCACVPDAELDEIDAGGKVAHGDAMLKPYDNCEPQARECFYRV",
                "length": 287
            },
            "evidence": [
                {
                    "id": "Q6AY62",
                    "url": "https://omabrowser.org/oma/group/Q6AY62/",
                    "database": "OMA"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "extracellular region",
                        "id": "GO:0005576",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AY62",
                                "url": "https://www.uniprot.org/uniprot/Q6AY62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AY62",
                                "url": "https://www.uniprot.org/uniprot/Q6AY62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endomembrane system",
                        "id": "GO:0012505",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AY62",
                                "url": "https://www.uniprot.org/uniprot/Q6AY62"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "positive regulation of neuron differentiation",
                        "id": "GO:0045666",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AY62",
                                "url": "https://www.uniprot.org/uniprot/Q6AY62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neuron differentiation",
                        "id": "GO:0030182",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AY62",
                                "url": "https://www.uniprot.org/uniprot/Q6AY62"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "heme binding",
                        "id": "GO:0020037",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q6AY62",
                                "url": "https://www.uniprot.org/uniprot/Q6AY62"
                            }
                        ],
                        "pmid": ""
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                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
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}