{ "uniprot_canonical_ac": "Q67FY2-1", "uniprot_ac": "Q67FY2", "uniprot_id": "BCL9L_MOUSE", "mass": { "chemical_mass": 156680.0, "monoisotopic_mass": 156680.0 }, "refseq": { "ac": "NP_084532", "name": "B-cell CLL/lymphoma 9-like protein isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084532" }, "gene_names": [ { "name": "Bcl9l", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q67FY2", "id": "Q67FY2" }, { "name": "B9L; BCL9-2; DLNB11", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084532", "id": "NP_084532" }, { "name": "B9l", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q67FY2", "id": "Q67FY2" }, { "name": "Bcl9l", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084532", "id": "NP_084532" } ], "protein_names": [ { "name": "B-cell CLL/lymphoma 9-like protein", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q67FY2" }, { "name": "B-cell CLL/lymphoma 9-like protein isoform 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084532", "id": "NP_084532" }, { "name": "B-cell CLL/lymphoma 9-like protein; nuclear co-factor of beta-catenin signalling; protein BCL9-2; BCL9-like protein; B-cell lymphoma 9-like protein; BCL9-related beta-catenin-binding protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084532", "id": "NP_084532" }, { "name": "B-cell lymphoma 9-like protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q67FY2" }, { "name": "BCL9-like protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q67FY2" }, { "name": "BCL9-related beta-catenin-binding protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q67FY2" }, { "name": "Protein BCL9-2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q67FY2" } ], "function": [ { "annotation": "BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer.", "evidence": [ { "database": "RefSeq", "id": "NP_084532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084532" }, { "database": "PubMed", "id": "33767438", "url": "https://glygen.org/publication/PubMed/33767438" } ] }, { "annotation": "Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1.", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2#function" }, { "database": "PubMed", "id": "15371335", "url": "https://glygen.org/publication/PubMed/15371335" } ] } ], "disease": [], "snv": [ { "evidence": [ { "id": "rs3388988720", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388988720" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 770, "end_pos": 770, "sequence_org": "N", "sequence_mut": "S", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (NMN->NMS).", "chr_id": "9", "chr_pos": "44418361", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N770", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Bcl9l", "url": "https://www.uniprot.org/uniprot/Q67FY2", "locus": { "chromosome": "9", "start_pos": 44423193, "end_pos": 44394122, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000063382", "url": "https://www.ensembl.org/id/ENSMUSG00000063382" } ] } } ], "crossref": [ { "id": "ENSMUSG00000063382", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000063382", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "80288", "url": "https://www.ncbi.nlm.nih.gov/gene/80288", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q67FY2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q67FY2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024670", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024670", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:80288", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:80288", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1933114", "url": "http://www.informatics.jax.org/marker/MGI:1933114", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "Q67FY2", "url": "https://oglcnac.org/atlas/detail/Q67FY2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "Q67FY2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q67FY2", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "NMMAEQP", "url": "https://omabrowser.org/oma/group/NMMAEQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "4259564at2759", "url": "http://www.orthodb.org/?query=4259564at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15185:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15185:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11502", "url": "http://pfam.xfam.org/family/PF11502", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q67FY2", "url": "http://purl.obolibrary.org/obo/PR_Q67FY2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-MMU-201722", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-201722", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_084532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1W2P7G4", "url": "https://www.uniprot.org/uniprot/A0A1W2P7G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2P7G4-1", "url": "https://www.uniprot.org/uniprot/A0A1W2P7G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q67FY2-1", "url": "https://www.uniprot.org/uniprot/Q67FY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q67FY2-2", "url": "https://www.uniprot.org/uniprot/Q67FY2-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIAAAHNCNVADPAMVTPQLGPGQTAQLPLSESSAPGPQHGPQPGLRPDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAPKVPPTPEPLPLNTPSAGTPQSQPPPLPPPPPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAATANNPLPPGGDPGSAPGSALLGEATPTGNGQRNLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPSAAQPPPSAPPGGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSMPMEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPAMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGTVGTARLSHMPLPPASNPPGSVHLASNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLSSSLGVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLSINSSSTLGNVEQGALPPSAPRNSSSAPPANPSSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNPAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGSSQNSMMMAPGGPDSLNAPCGPVPSSSQMMSFPPRLQQPHGAMAPTGAGGPGLQQHYPSGMALPPEDLPTQPPGPIPPQQHLMGKGMTGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPTPGSMANLPF", "length": 1494, "header": "sp|Q67FY2-1|BCL9L_MOUSE Isoform 1 of B-cell CLL/lymphoma 9-like protein OS=Mus musculus OX=10090 GN=Bcl9l PE=1 SV=1 CANONICAL=Q67FY2-1" }, "isoforms": [ { "isoform_ac": "A0A1W2P7G4-1", "url": "", "sequence": { "sequence": "MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQGPTCNLGSKGVGAGSHGAKANQISPS", "length": 90, "header": "tr|A0A1W2P7G4-1|A0A1W2P7G4_MOUSE Computationally mapped isoform of B cell CLL/lymphoma 9-like OS=Mus musculus OX=10090 GN=Bcl9l PE=1 SV=1 CANONICAL=Q67FY2-1" }, "locus": { "chromosome": "9", "start_pos": 44412285, "end_pos": 44410821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000218913.2", "url": "https://www.ensembl.org/id/ENSMUST00000218913.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000151653.2", "url": "https://www.ensembl.org/id/ENSMUSP00000151653.2" } ] } }, { "isoform_ac": "Q67FY2-1", "url": "", "sequence": { "sequence": "MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIAAAHNCNVADPAMVTPQLGPGQTAQLPLSESSAPGPQHGPQPGLRPDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAPKVPPTPEPLPLNTPSAGTPQSQPPPLPPPPPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAATANNPLPPGGDPGSAPGSALLGEATPTGNGQRNLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPSAAQPPPSAPPGGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSMPMEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPAMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGTVGTARLSHMPLPPASNPPGSVHLASNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLSSSLGVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLSINSSSTLGNVEQGALPPSAPRNSSSAPPANPSSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNPAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGSSQNSMMMAPGGPDSLNAPCGPVPSSSQMMSFPPRLQQPHGAMAPTGAGGPGLQQHYPSGMALPPEDLPTQPPGPIPPQQHLMGKGMTGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPTPGSMANLPF", "length": 1494, "header": "sp|Q67FY2-1|BCL9L_MOUSE Isoform 1 of B-cell CLL/lymphoma 9-like protein OS=Mus musculus OX=10090 GN=Bcl9l PE=1 SV=1 CANONICAL=Q67FY2-1" }, "locus": { "chromosome": "9", "start_pos": 44421077, "end_pos": 44410821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000074989", "url": "https://www.ensembl.org/id/ENSMUST00000074989" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000074516", "url": "https://www.ensembl.org/id/ENSMUSP00000074516" } ] } }, { "isoform_ac": "Q67FY2-2", "url": "", "sequence": { "sequence": "MHPENKLTNHGKTGNGGAQSQHQNVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIAAAHNCNVADPAMVTPQLGPGQTAQLPLSESSAPGPQHGPQPGLRPDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAPKVPPTPEPLPLNTPSAGTPQSQPPPLPPPPPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAATANNPLPPGGDPGSAPGSALLGEATPTGNGQRNLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPSAAQPPPSAPPGGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSMPMEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPAMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGTVGTARLSHMPLPPASNPPGSVHLASNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLSSSLGVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLSINSSSTLGNVEQGALPPSAPRNSSSAPPANPSSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNPAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGSSQNSMMMAPGGPDSLNAPCGPVPSSSQMMSFPPRLQQPHGAMAPTGAGGPGLQQHYPSGMALPPEDLPTQPPGPIPPQQHLMGKGMTGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPTPGSMANLPF", "length": 1457, "header": "sp|Q67FY2-2|BCL9L_MOUSE Isoform 2 of B-cell CLL/lymphoma 9-like protein OS=Mus musculus OX=10090 GN=Bcl9l PE=1 SV=1 CANONICAL=Q67FY2-1" }, "locus": { "chromosome": "9", "start_pos": 44421077, "end_pos": 44412127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000220303", "url": "https://www.ensembl.org/id/ENSMUST00000220303" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000151342", "url": "https://www.ensembl.org/id/ENSMUSP00000151342" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 893, "start_aa": "Ser", "end_pos": 893, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser893", "evidence": [ { "id": "Q67FY2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q67FY2" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 931, "start_aa": "Ser", "end_pos": 931, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser931", "evidence": [ { "id": "Q67FY2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q67FY2" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "phosphorylation": [ { "start_pos": 1001, "end_pos": 1001, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "site_lbl": "Ser1001" }, { "start_pos": 1007, "end_pos": 1007, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "site_lbl": "Ser1007" }, { "start_pos": 1014, "end_pos": 1014, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser1014" }, { "start_pos": 116, "end_pos": 116, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser116" }, { "start_pos": 118, "end_pos": 118, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser118" }, { "start_pos": 21, "end_pos": 21, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser21" }, { "start_pos": 25, "end_pos": 25, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser25" }, { "start_pos": 421, "end_pos": 421, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser421" }, { "start_pos": 511, "end_pos": 511, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Thr511" }, { "start_pos": 747, "end_pos": 747, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser747" }, { "start_pos": 810, "end_pos": 810, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser810" }, { "start_pos": 88, "end_pos": 88, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser88" }, { "start_pos": 912, "end_pos": 912, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "site_lbl": "Ser912" }, { "start_pos": 923, "end_pos": 923, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "site_lbl": "Ser923" }, { "start_pos": 935, "end_pos": 935, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser935" }, { "start_pos": 939, "end_pos": 939, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "site_lbl": "Ser939" }, { "start_pos": 944, "end_pos": 944, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "site_lbl": "Ser944" }, { "start_pos": 972, "end_pos": 972, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "site_lbl": "Ser972" }, { "start_pos": 984, "end_pos": 984, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "site_lbl": "Ser984" }, { "start_pos": 988, "end_pos": 988, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "site_lbl": "Ser988" }, { "start_pos": 994, "end_pos": 994, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "site_lbl": "Ser994" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.", "journal": "Genes Dev.", "date": "2004", "authors": "Brembeck FH, Schwarz-Romond T, Bakkers J, Wilhelm S, Hammerschmidt M, Birchmeier W", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "reference": [ { "type": "PubMed", "id": "15371335", "url": "https://glygen.org/publication/PubMed/15371335" } ] }, { "title": "Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling.", "journal": "Cancer Res.", "date": "2004", "authors": "Adachi S, Jigami T, Yasui T, Nakano T, Ohwada S, Omori Y, Sugano S, Ohkawara B, Shibuya H, Nakamura T, Akiyama T", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "reference": [ { "type": "PubMed", "id": "15574752", "url": "https://glygen.org/publication/PubMed/15574752" } ] }, { "title": "Crystal structure of a beta-catenin/BCL9/Tcf4 complex.", "journal": "Mol. Cell", "date": "2006", "authors": "Sampietro J, Dahlberg CL, Cho US, Hinds TR, Kimelman D, Xu W", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "reference": [ { "type": "PubMed", "id": "17052462", "url": "https://glygen.org/publication/PubMed/17052462" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "iPTMnet", "id": "Q67FY2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q67FY2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.", "journal": "Mol. Cell", "date": "2013", "authors": "Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" }, { "database": "UniProtKB", "id": "A0A1W2P7G4", "url": "https://www.uniprot.org/uniprot/A0A1W2P7G4" } ], "reference": [ { "type": "PubMed", "id": "23806337", "url": "https://glygen.org/publication/PubMed/23806337" } ] }, { "title": "Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.", "journal": "Mol. Cell. Proteomics", "date": "2014", "authors": "Guo A, Gu H, Zhou J, Mulhern D, Wang Y, Lee KA, Yang V, Aguiar M, Kornhauser J, Jia X, Ren J, Beausoleil SA, Silva JC, Vemulapalli V, Bedford MT, Comb MJ", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "reference": [ { "type": "PubMed", "id": "24129315", "url": "https://glygen.org/publication/PubMed/24129315" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q67FY2", "url": "https://oglcnac.org/atlas/detail/Q67FY2" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer.", "journal": "Oncogene", "date": "2021", "authors": "Wang X, Feng M, Xiao T, Guo B, Liu D, Liu C, Pei J, Liu Q, Xiao Y, Rosin-Arbesfeld R, Shi Y, Zhou Y, Yang M, Feng YX, Jiang Y, Shao Z, Yu K, Zhu D", "evidence": [ { "database": "RefSeq", "id": "NP_084532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084532" } ], "reference": [ { "type": "PubMed", "id": "33767438", "url": "https://glygen.org/publication/PubMed/33767438" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q67FY2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q67FY2" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "pathway": [ { "id": "mmu:80288", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:80288", "resource": "KEGG Pathway" }, { "id": "R-MMU-201722", "name": "Formation of the beta-catenin:TCF transactivating complex", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AJN4-1", "protein_name": "BCL9 like", "gene_name": "Bcl9l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGATHNCNVADPAMVAPQLGPGQTAQLPLSENSAPGPQHGPPPGLRPDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAPKVPPTPEPLPLNTPSAGTPQSQPPPLPPPPPAPGSAPPALPQEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAATANNPLPPGGDPGSAPGSALLGEATPTGNGQRNLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAVEGGPPAQAPSAAQQPPSAPPPGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGTQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSIPMEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQTHRQMDPTMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMAGPQKMLMPSQFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGAVGTARLSHMPLPPASNPPGSVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLSSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNINSSSTLGNLEQGALPPAGPRNSSSAPPANPPSSLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNPAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGPSQNSMMMAPGGPDSLNTPCGPVPSSSQMMSFPPRLQQPHGAMAATGGGGPGLQQHYPSGMALPPEDLPNQPPGPIPSQQHLMGKGMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKNENQPPKAQPPNLHLMNLQNMMAEQAPSRPPNLPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYTQPPHMLSPQGSLMAPPPQQNLMVSHPLRQRSVSLDSQMGYLPTPGGMANLPF", "length": 1494 }, "evidence": [ { "id": "45226442", "url": "http://www.informatics.jax.org/homology/45226442", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86UU0-1", "protein_name": "B-cell CLL/lymphoma 9-like protein", "gene_name": "BCL9L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQGPTCNVGSKGVGAGNHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRDRSVSVDSGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGATHNCNVADPAMAAPQLGPGQTTQLPLSESSVPGAPHGPPPGLRPDAPGGGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPPPPQQPPTAPPSGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPPGGDMGQQMNMMIQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGSRPLQDMMGMGGMMVRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRGGPPFPGPRFPGNQIQRVPGFGGMQSMPMEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNTMPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQAHRQMDPAMFPGQMAGGEGLAGTPMGMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDLMGPQGLSPEEMARVRAQNSSGVMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSHMPLPPASNPPGTVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLNMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYSQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPAPGGMANLPF", "length": 1499 }, "evidence": [ { "id": "45226442", "url": "http://www.informatics.jax.org/homology/45226442", "database": "MGI" }, { "id": "Q67FY2", "url": "https://omabrowser.org/oma/group/Q67FY2/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" }, { "name": "beta-catenin-TCF complex", "id": "GO:1990907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990907", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" }, { "name": "regulation of cell morphogenesis", "id": "GO:0022604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022604", "evidence": [ { "database": "UniProtKB", "id": "Q67FY2", "url": "https://www.uniprot.org/uniprot/Q67FY2" } ], "pmid": "" }, { "name": "skeletal muscle cell differentiation", "id": "GO:0035914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035914", 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