{ "uniprot_canonical_ac": "Q64700-1", "uniprot_ac": "Q64700", "uniprot_id": "RBL2_MOUSE", "mass": { "chemical_mass": 127485.0, "monoisotopic_mass": 127485.0 }, "refseq": {}, "gene_names": [ { "name": "Rbl2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q64700", "id": "Q64700" } ], "protein_names": [ { "name": "Retinoblastoma-like protein 2", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q64700" }, { "name": "130 kDa retinoblastoma-associated protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64700" }, { "name": "RBR-2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64700" }, { "name": "Retinoblastoma-related protein 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64700" }, { "name": "p130", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64700" }, { "name": "pRb2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64700" } ], "function": [ { "annotation": "Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.", "evidence": [ { "database": "UniProtKB", "id": "Q64700", "url": "https://www.uniprot.org/uniprot/Q64700#function" }, { "database": "PubMed", "id": "15750587", "url": "https://glygen.org/publication/PubMed/15750587" } ] } ], "disease": [ { "disease_id": "DOID:1059", "recommended_name": { "id": "DOID:1059", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills." }, "synonyms": [], "evidence": [ { "id": "1059", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ] }, { "disease_id": "DOID:162", "recommended_name": { "id": "DOID:162", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis." }, "synonyms": [ { "id": "DOID:162", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:162", "name": "malignant neoplasm", "description": "" }, { "id": "DOID:162", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:162", "name": "malignant tumor", "description": "" }, { "id": "DOID:162", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:162", "name": "primary cancer", "description": "" } ], "evidence": [ { "id": "162", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:162" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q64700", "url": "https://www.uniprot.org/uniprot/Q64700" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Rbl2", "url": "https://www.uniprot.org/uniprot/Q64700", "locus": { "chromosome": "8", "start_pos": 91850472, "end_pos": 91796685, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000031666", "url": "https://www.ensembl.org/id/ENSMUSG00000031666" } ] } } ], "crossref": [ { "id": "ENSMUSG00000031666", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000031666", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00043", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00043", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20606", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20606", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "Q64700", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q64700*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:19651", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:19651", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "105085", "url": "http://www.informatics.jax.org/marker/MGI:105085", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "Q64700", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q64700", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "MHWLACA", "url": "https://omabrowser.org/oma/group/MHWLACA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "519973at2759", "url": "http://www.orthodb.org/?query=519973at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13742:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13742:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01857", "url": "http://pfam.xfam.org/family/PF01857", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01858", "url": "http://pfam.xfam.org/family/PF01858", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF11934", "url": "http://pfam.xfam.org/family/PF11934", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q64700", "url": "http://purl.obolibrary.org/obo/PR_Q64700", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-MMU-1538133", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1538133", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-69231", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-69231", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "A0A1B0GR06", "url": "https://www.uniprot.org/uniprot/A0A1B0GR06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1B0GR06-1", "url": "https://www.uniprot.org/uniprot/A0A1B0GR06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1B0GRM0", "url": "https://www.uniprot.org/uniprot/A0A1B0GRM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1B0GRM0-1", "url": "https://www.uniprot.org/uniprot/A0A1B0GRM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q64700", "url": "https://www.uniprot.org/uniprot/Q64700", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q64700-1", "url": "https://www.uniprot.org/uniprot/Q64700-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGGNQSPPPPPAAAASSEEEEEDGDAADRAQPAGSPSHQIQQRFEELCSRLNMDEAARAEAWSSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTAEGNYVSLTRILRCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTTSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLSEDCHPKDSKASSDPPCVIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLFEKKLLKGKEENLTGFLEPGNFGESFKAVNKAYEEYVLAAGNLDERVFLGEDAEEEVGTLSRCLSAASGTESAERTQMRDILQQHLDKSKALRVCTPLTGVRYVQENSPCVTPVSTAAHSLSRLHTMLSGLRNAPSEKLERILRSCSRDPTQAIADRLKEMYEIYSQHFQPDENFSNCAKEIANKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGVLEHDAFHRSLLACCLEVVAFSHKPPGNFPFIAEIFDVPHYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWKTKSPLWDRIRDNENRVPTCEEVMPPQNLERTDEIYIAGSPLTPRRVGEVRADAGGLGRSITSPTTLYDRYSSPTVSTTRRRLFENDSPSEGSTSGRIPPQPLVNAVPVQNVPGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVAGSIQPLSAQALAGSLSSQQVTGTTLQVPGPVAIQQISPGGQQQNPGQPLTSSSIRPRKTSSLALFFRKVYYLAGVRLRDLCIKLDISDELRKKIWTCFEFSIIQCTELMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQARSQVYRSVLIKGKRRNSGSSESRSHQNSPTELNTDRASRDSSPVMRSNSTLPVPQPSSAPPTPTRLTGASSDVEEEERGDLIQFYNNIYRKQIQAFAMKYSQANAQTDTPPLSPYPFVRTGSPRRVQLSQSHPIYISPHNNEAMPSPREKIFYYFSNSPSKRLREINSMIRTGETPTKKRGILLDDGSESPAKRICPENHSALLRRLQDVANDRGSQ", "length": 1135, "header": "sp|Q64700-1|RBL2_MOUSE Isoform 1 of Retinoblastoma-like protein 2 OS=Mus musculus OX=10090 GN=Rbl2 PE=1 SV=3 CANONICAL=Q64700-1" }, "isoforms": [ { "isoform_ac": "A0A1B0GR06-1", "url": "", "sequence": { "sequence": "MASGGNQSPPPPPAAAASSEEEEEDGDAADRAQPAGSPSHQIQQRFEELCSRLNMDEAARAEAWSSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTAEGNYVSLTRILRCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTTSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLSEDCHPKDSKASSDPPCVIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLFEKKLLKGKEENLTGFLEPGNFGESFKAVNKAYEEYVLAAGNLDERVFLGEDAEEEVGTLSRCLSAASGTESAERTQMRDILQQHLDKSKALRVCTPLTGVRYVQENSPCVTPVSTAAHSLSRLHTMLSGLRNAPSEKLERILRSCSRDPTQAIADRLKEMYEIYSQHFQPDENFSNCAKEMLYYKVLESVIEQEQKRLGDMDLSGVLEHDAFHRSLLACCLEVVAFSHKPPGNFPFIAEIFDVPHYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWKTKSPLWDRIRDNENRVPTCEEVMPPQNLERTDEIYIAGSPLTPRRVGEVRADAGGLGRSITSPTTLYDRYSSPTVSTTRRRLFENDSPSEGSTSGRIPPQPLVNAVPVQNVPGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVAGSIQPLSAQALAGSLSSQQVTGTTLQVPGPVAIQQISPGGQQQNPGQPLTSSSIRPRKTSSLALFFRKVYYLAGVRLRDLCIKLDISDELRKKIWTCFEFSIIQCTELMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQARSQVYRSVLIKGKRRNSGSSESRSHQNSPTELNTDRASRDSSPVMRSNSTLPVPQPSSAPPTPTRLTGASSDVEEEERGDLIQFYNNIYRKQIQAFAMKYSQANAQTDTPPLSPYPFVRTGSPRRVQLSQSHPIYISPHNNEAMPSPREKIFYYFSNSPSKRLREINSMIRTGETPTKKRGILLDDGSESPAKRICPENHSALLRRLQDVANDRGSQ", "length": 1125, "header": "tr|A0A1B0GR06-1|A0A1B0GR06_MOUSE Computationally mapped isoform of RB transcriptional corepressor like 2 OS=Mus musculus OX=10090 GN=Rbl2 PE=1 SV=1 CANONICAL=Q64700-1" }, "locus": { "chromosome": "8", "start_pos": 91849071, "end_pos": 91796804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000209518.2", "url": "https://www.ensembl.org/id/ENSMUST00000209518.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000147327.2", "url": "https://www.ensembl.org/id/ENSMUSP00000147327.2" } ] } }, { "isoform_ac": "A0A1B0GRM0-1", "url": "", "sequence": { "sequence": "MASGGNQSPPPPPAAAASSEEEEEDGDAADRAQPAGSPSHQIQQRFEELCSRLNMDEAARAEAWSSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTAEGNYVSLTRILRCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTTSEIFHFCWVLFIYAKGLSEDCHPKDSKASSDPPCVIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLFEKKLLKGKEENLTGFLEPGNFGESFKAVNKAYEEYVLAAGNLDERVFLGEDAEEEVGTLSRCLSAASGTESAERTQMRDILQQHLDKSKALRVCTPLTGVRYVQENSPCVTPVSTAAHSLSRLHTMLSGLRNAPSEKLERILRSCSRDPTQAIADRLKEMYEIYSQHFQPDENFSNCAKEIANKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGVLEHDAFHRSLLACCLEVVAFSHKPPGNFPFIAEIFDVPHYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWKTKSPLWDRIRDNENRVPTCEEVMPPQNLERTDEIYIAGSPLTPRRVGEVRADAGGLGRSITSPTTLYDRYSSPTVSTTRRRLFENDSPSEGSTSGRIPPQPLVNAVPVQNVPGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVAGSIQPLSAQALAGSLSSQQVTGTTLQVPGPVAIQQISPGGQQQNPGQPLTSSSIRPRKTSSLALFFRKVYYLAGVRLRDLCIKLDISDELRKKIWTCFEFSIIQCTELMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQARSQVYRSVLIKGKRRNSGSSESRSHQNSPTELNTDRASRDSSPVMRSNSTLPVPQPSSAPPTPTRLTGASSDVEEEERGDLIQFYNNIYRKQIQAFAMKYSQANAQTDTPPLSPYPFVRTGSPRRVQLSQSHPIYISPHNNEAMPSPREKIFYYFSNSPSKRLREINSMIRTGETPTKKRGILLDDGSESPAKRICPENHSALLRRLQDVANDRGSQ", "length": 1092, "header": "tr|A0A1B0GRM0-1|RBL2_MOUSE Computationally mapped isoform of Retinoblastoma-like protein 2 OS=Mus musculus OX=10090 GN=Rbl2 PE=1 SV=1 CANONICAL=Q64700-1" }, "locus": { "chromosome": "8", "start_pos": 91849071, "end_pos": 91796804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000211136.2", "url": "https://www.ensembl.org/id/ENSMUST00000211136.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000147579.2", "url": "https://www.ensembl.org/id/ENSMUSP00000147579.2" } ] } }, { "isoform_ac": "Q64700-1", "url": "", "sequence": { "sequence": "MASGGNQSPPPPPAAAASSEEEEEDGDAADRAQPAGSPSHQIQQRFEELCSRLNMDEAARAEAWSSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTAEGNYVSLTRILRCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTTSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLSEDCHPKDSKASSDPPCVIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLFEKKLLKGKEENLTGFLEPGNFGESFKAVNKAYEEYVLAAGNLDERVFLGEDAEEEVGTLSRCLSAASGTESAERTQMRDILQQHLDKSKALRVCTPLTGVRYVQENSPCVTPVSTAAHSLSRLHTMLSGLRNAPSEKLERILRSCSRDPTQAIADRLKEMYEIYSQHFQPDENFSNCAKEIANKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGVLEHDAFHRSLLACCLEVVAFSHKPPGNFPFIAEIFDVPHYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWKTKSPLWDRIRDNENRVPTCEEVMPPQNLERTDEIYIAGSPLTPRRVGEVRADAGGLGRSITSPTTLYDRYSSPTVSTTRRRLFENDSPSEGSTSGRIPPQPLVNAVPVQNVPGETVSVTPVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVAGSIQPLSAQALAGSLSSQQVTGTTLQVPGPVAIQQISPGGQQQNPGQPLTSSSIRPRKTSSLALFFRKVYYLAGVRLRDLCIKLDISDELRKKIWTCFEFSIIQCTELMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQARSQVYRSVLIKGKRRNSGSSESRSHQNSPTELNTDRASRDSSPVMRSNSTLPVPQPSSAPPTPTRLTGASSDVEEEERGDLIQFYNNIYRKQIQAFAMKYSQANAQTDTPPLSPYPFVRTGSPRRVQLSQSHPIYISPHNNEAMPSPREKIFYYFSNSPSKRLREINSMIRTGETPTKKRGILLDDGSESPAKRICPENHSALLRRLQDVANDRGSQ", "length": 1135, "header": "sp|Q64700-1|RBL2_MOUSE Isoform 1 of Retinoblastoma-like protein 2 OS=Mus musculus OX=10090 GN=Rbl2 PE=1 SV=3 CANONICAL=Q64700-1" }, "locus": { "chromosome": "8", "start_pos": 91849071, "end_pos": 91796804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000034091", "url": "https://www.ensembl.org/id/ENSMUST00000034091" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000034091", "url": "https://www.ensembl.org/id/ENSMUSP00000034091" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "Q64700", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q64700" }, { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" } ] } ], "phosphorylation": [ { "start_pos": 1027, "end_pos": 1027, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "phospho.ELM", "id": "Q64700", "url": "http://phospho.elm.eu.org/byAccession/Q64700.html" }, { "database": "iPTMnet", "id": "Q64700", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q64700" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ], "site_lbl": "Thr1027" }, { "start_pos": 1031, "end_pos": 1031, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q64700", "url": "https://www.uniprot.org/uniprot/Q64700" } ], "site_lbl": "Ser1031" }, { "start_pos": 1064, "end_pos": 1064, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q64700", "url": "https://www.uniprot.org/uniprot/Q64700" } ], "site_lbl": "Ser1064" }, { "start_pos": 1076, "end_pos": 1076, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q64700", "url": "https://www.uniprot.org/uniprot/Q64700" } ], "site_lbl": "Ser1076" }, { "start_pos": 1108, "end_pos": 1108, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q64700", "url": "https://www.uniprot.org/uniprot/Q64700" } ], "site_lbl": "Ser1108" }, { "start_pos": 410, "end_pos": 410, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q64700", "url": "https://www.uniprot.org/uniprot/Q64700" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": 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