{ "uniprot_canonical_ac": "Q64455-1", "uniprot_ac": "Q64455", "uniprot_id": "PTPRJ_MOUSE", "mass": { "chemical_mass": 136769.0, "monoisotopic_mass": 136769.0 }, "refseq": { "ac": "XP_006499057", "name": "receptor-type tyrosine-protein phosphatase eta isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006499057" }, "gene_names": [ { "name": "Ptprj", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q64455", "id": "Q64455" }, { "name": "BET; Byp; CD148; DEP-1; Ptpb2; PTPbeta2; R-PTP-eta; R-PTP-J; RPTPJ; Scc-1; Scc1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006499057", "id": "XP_006499057" }, { "name": "Byp", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q64455", "id": "Q64455" }, { "name": "Ptprj", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006499057", "id": "XP_006499057" }, { "name": "Scc1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q64455", "id": "Q64455" } ], "protein_names": [ { "name": "Receptor-type tyrosine-protein phosphatase eta", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q64455" }, { "name": "3.1.3.48", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64455" }, { "name": "HPTP beta-like tyrosine phosphatase", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64455" }, { "name": "Protein-tyrosine phosphatase eta", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64455" }, { "name": "Protein-tyrosine phosphatase receptor type J", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64455" }, { "name": "R-PTP-J", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64455" }, { "name": "R-PTP-eta", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64455" }, { "name": "Susceptibility to colon cancer 1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q64455" }, { "name": "receptor-type tyrosine-protein phosphatase eta isoform 1 precursor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033008", "id": "NP_033008" }, { "name": "receptor-type tyrosine-protein phosphatase eta isoform 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129129", "id": "NP_001129129" }, { "name": "receptor-type tyrosine-protein phosphatase eta isoform X5", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006499057", "id": "XP_006499057" }, { "name": "receptor-type tyrosine-protein phosphatase eta; protein-tyrosine phosphatase eta; susceptibility to colon cancer 1; HPTP beta-like tyrosine phosphatase; colon tumor susceptibility 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129129", "id": "NP_001129129" } ], "function": [ { "annotation": "CD148 Deficiency in Fibroblasts Promotes the Development of Pulmonary Fibrosis.", "evidence": [ { "database": "RefSeq", "id": "NP_001129129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129129" }, { "database": "PubMed", "id": "33784491", "url": "https://glygen.org/publication/PubMed/33784491" }, { "database": "RefSeq", "id": "NP_033008", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033008" } ] }, { "annotation": "PTPRJ promotes osteoclast maturation and activity by inhibiting Cbl-mediated ubiquitination of NFATc1 in late osteoclastogenesis.", "evidence": [ { "database": "RefSeq", "id": "NP_001129129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129129" }, { "database": "PubMed", "id": "33605542", "url": "https://glygen.org/publication/PubMed/33605542" }, { "database": "RefSeq", "id": "NP_033008", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033008" } ] }, { "annotation": "The protein tyrosine phosphatase PTPRJ/DEP-1 contributes to the regulation of the Notch-signaling pathway and sprouting angiogenesis.", "evidence": [ { "database": "RefSeq", "id": "NP_001129129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129129" }, { "database": "PubMed", "id": "31598898", "url": "https://glygen.org/publication/PubMed/31598898" }, { "database": "RefSeq", "id": "NP_033008", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033008" } ] }, { "annotation": "Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2 (By similarity). Plays a role in cell adhesion, migration, proliferation and differentiation (PubMed:18249142). Involved in vascular development (PubMed:12588999). May be involved in the mechanism of contact inhibition of cell growth (PubMed:12771128). Regulator of macrophage adhesion and spreading (PubMed:19268662). Positively affects cell-matrix adhesion (PubMed:12833140). Positive regulator of platelet activation and thrombosis (PubMed:19246339). Negative regulator of cell proliferation (By similarity). Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR (PubMed:12833140). Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation (By similarity). Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation (By similarity). Enhances the barrier function of epithelial junctions during reassembly (By similarity). Negatively regulates T-cell receptor (TCR) signaling (By similarity). Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling (PubMed:12913111).", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455#function" }, { "database": "PubMed", "id": "19268662", "url": "https://glygen.org/publication/PubMed/19268662" }, { "database": "PubMed", "id": "12913111", "url": "https://glygen.org/publication/PubMed/12913111" }, { "database": "PubMed", "id": "18249142", "url": "https://glygen.org/publication/PubMed/18249142" }, { "database": "PubMed", "id": "19246339", "url": "https://glygen.org/publication/PubMed/19246339" }, { "database": "PubMed", "id": "12833140", "url": "https://glygen.org/publication/PubMed/12833140" }, { "database": "UniProtKB", "id": "Q12913", "url": "https://www.uniprot.org/uniprot/Q12913#function" }, { "database": "PubMed", "id": "12771128", "url": "https://glygen.org/publication/PubMed/12771128" }, { "database": "PubMed", "id": "12588999", "url": "https://glygen.org/publication/PubMed/12588999" } ] } ], "disease": [ { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "evidence": [ { "id": "10763", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] }, { "disease_id": "DOID:1588", "recommended_name": { "id": "DOID:1588", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood." }, "synonyms": [ { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia 4", "description": "Any thrombocytopenia in which the cause of the disease is a mutation in the CYCS gene." }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "CYCS thrombocytopenia", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia 4", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia caused by mutation in CYCS", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia type 4", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "THC4", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia, autosomal dominant, 4", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "thrombocytopenia, X-linked, with or without dyserythropoietic anemia", "description": "An X-linked condition caused by mutation(s) in the GATA1 gene, encoding erythroid transcription factor. It is characterized by thrombocytopenia, as well as abnormal platelet function and morphology. Dyserythropoietic anemia of variable severity may also be present." }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "X-linked thrombocytopenia, with or without dyserythropoietic Anaemia", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "X-linked thrombocytopenia, with or without dyserythropoietic Anemia", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "thrombocytopenia, X-linked, with or without dyserythropoietic anemia", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "thrombocytopenia, X-linked, with or without dyserythropoietic anemia, X-linked recessive", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "XLTDA", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia 2", "description": "An autosomal dominant disorder caused by mutation(s) in the ANKRD26 gene, encoding ANKRD26 protein. Additionally, in one family, a mutation(s) has been identified in the MASTL gene, encoding serine/threonine-protein kinase greatwall. The condition is characterized by mild to moderate bruisability." }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia 2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia type 2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "THC2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia autosomal dominant 2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "thrombocytopenia 3", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "THC3", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "thrombocytopenia 3", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "thrombocytopenia, autosomal recessive, 3", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "X-linked thrombocytopenia with normal platelets", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia type 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia, X-linked, X-linked recessive", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia, X-linked, intermittent, X-linked recessive", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "THC", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "THC1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "X-linked thrombocytopenia", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "XLT", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia, X-linked", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia, X-linked, 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia, X-linked, intermittent", "description": "" }, { "id": "MIM:612004", "resource": "MIM", "url": "https://www.omim.org/entry/612004", "name": "Thrombocytopenia 4", "description": "Thrombocytopenia 4" }, { "id": "MIM:300367", "resource": "MIM", "url": "https://www.omim.org/entry/300367", "name": "X-linked dyserythropoietic anemia and thrombocytopenia", "description": "X-linked dyserythropoietic anemia and thrombocytopenia" }, { "id": "MIM:188000", "resource": "MIM", "url": "https://www.omim.org/entry/188000", "name": "Thrombocytopenia 2", "description": "Thrombocytopenia 2" }, { "id": "MIM:273900", "resource": "MIM", "url": "https://www.omim.org/entry/273900", "name": "Thrombocytopenia 3", "description": "Thrombocytopenia 3" }, { "id": "MIM:313900", "resource": "MIM", "url": "https://www.omim.org/entry/313900", "name": "Thrombocytopenia 1", "description": "Thrombocytopenia 1" } ], "evidence": [ { "id": "1588", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ] }, { "disease_id": "DOID:3907", "recommended_name": { "id": "DOID:3907", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell." }, "synonyms": [ { "id": "DOID:3907", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3907", "name": "Epidermoid cell carcinoma of the lung", "description": "" } ], "evidence": [ { "id": "3907", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ] }, { "disease_id": "DOID:3910", "recommended_name": { "id": "DOID:3910", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin." }, "synonyms": [ { "id": "DOID:3910", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3910", "name": "bronchogenic lung adenocarcinoma", "description": "" }, { "id": "DOID:3910", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3910", "name": "nonsmall cell adenocarcinoma", "description": "" } ], "evidence": [ { "id": "3910", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ] }, { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, advanced, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer with chromosomal instability, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectum cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectum neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": 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"length": 1164, "header": "tr|A2AWF8-1|PTPRJ_MOUSE Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase eta OS=Mus musculus OX=10090 GN=Ptprj PE=1 SV=1 CANONICAL=Q64455-1" }, "locus": { "chromosome": "2", "start_pos": 90301572, "end_pos": 90266757, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000111493.8", "url": "https://www.ensembl.org/id/ENSMUST00000111493.8" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000107119.2", "url": "https://www.ensembl.org/id/ENSMUSP00000107119.2" } ] } }, { "isoform_ac": "A2AWF9-1", "url": "", "sequence": { "sequence": "MCMDNVLGGFEMPQALLAQGAAASAVQTSDYKDRTQHGSGGIRTMGDPGRRVLCAGAAPNPIFDIEAVVSPTSVLLTWKHNDSGASECRIENKMESNLTFPVKNQTSCNITGLSPGTSYTFSIISVTTNETLNKTITTEPWPVSDLHVTSVGVTQARLTWSNANGTASYRMLIEELTTHSSVNISGLKPGTNNSFAFPESNETQADFAVAEEVPDANGTKRIPVTNLSQLHKNSLVSVDPPSGQDPSLTEILLTDLKPDTQYNATIYSQAANGTEGQPRNKVFKTNSTQVSDVRAMNISASSMTLTWKSNYDGSRTSIVYKIHVAGGTHSVNQTVNKTEAIILGLSSSTLYNITVHPFLGQTEGTPGFLQVYTSPDQVSDFRVTNVSTRAIGLAWRSNDSKSFEIFIKQDGGEKHRNASTGNQSYMVEDLKPGTSYHFEIIPRGPDGTEGLSSTVNGSTDPSAVTDIRVVNISTTEMQLEWQNTDDASGYTYHLVLESKSGSIIRTNSSQKWITVGSLTPGTLYNVTIFPEVDQIQGISNSITQYTRPSSVSHIEVNTTTTTAAIRWKNEDAASASYAYSVLILKTGDGSNVTSNFTKDPSILIPELIPGVSYTVKILTQVGDGTTSLVPGWNLFCTEPEPVTSFHCEVVPKEPALVLKWACPFGMYTGFELGVRSDSWDNMTRLENCTSDDDTECRTEVAYLNFSTSYNISIATLSCGKMALPAQNICTTGITDPPTPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVILTTGEAAQPSADVLKYTYEDFKRGASDTYVTYLIRIEEKGQSQGLSEVLNYEIDVGNQSTTLGYYNGRLEPLGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVFLPQDPGVICGAVFGCIFGALAITAVGGFIFWRKKRTDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPKYTAEIAENRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRTKCEEYWPSKQAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQNSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRAQKDSKVDLIYQNTTAMTIYENLEPSSLNVTMLLHPQLNDFGCWVLGPGCCWSARIQGLVDIWEDVNCPAESLSFRCGH", "length": 1299, "header": "tr|A2AWF9-1|PTPRJ_MOUSE Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase eta OS=Mus musculus OX=10090 GN=Ptprj PE=1 SV=1 CANONICAL=Q64455-1" }, "locus": { "chromosome": "2", "start_pos": 90309463, "end_pos": 90260349, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000111495.9", "url": "https://www.ensembl.org/id/ENSMUST00000111495.9" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000107121.3", "url": "https://www.ensembl.org/id/ENSMUSP00000107121.3" } ] } }, { "isoform_ac": "E9Q4S7-1", "url": "", "sequence": { "sequence": "MTRGGGRGSSRGRGSRELGATRGGWAPLAPPREAPASLRPRPLRARRARLRRVAAAAAAAMSPGKPGAGGAGTRRTGWRRRRRRRRLETETRAPGFGHTAGRVPGTFQGAQGMKPAARETRTPPRSPGLRWALLPLLLLLRQGQVLCAGAAPNPIFDIEAVVSPTSVLLTWKHNDSGASECRIENKMESNLTFPVKNQTSCNITGLSPGTSYTFSIISVTTNETLNKTITTEPWPVSDLHVTSVGVTQARLTWSNANGTASYRMLIEELTTHSSVNISGLKPGTNNSFAFPESNETQADFAVAEEVPDANGTKRIPVTNLSQLHKNSLVSVDPPSGQDPSLTEILLTDLKPDTQYNATIYSQAANGTEGQPRNKVFKTNSTQVSDVRAMNISASSMTLTWKSNYDGSRTSIVYKIHVAGGTHSVNQTVNKTEAIILGLSSSTLYNITVHPFLGQTEGTPGFLQVYTSPDQVSDFRVTNVSTRAIGLAWRSNDSKSFEIFIKQDGGEKHRNASTGNQSYMVEDLKPGTSYHFEIIPRGPDGTEGLSSTVNGSTDPSAVTDIRVVNISTTEMQLEWQNTDDASGYTYHLVLESKSGSIIRTNSSQKWITVGSLTPGTLYNVTIFPEVDQIQGISNSITQYTRPSSVSHIEVNTTTTTAAIRWKNEDAASASYAYSVLILKTGDGSNVTSNFTKDPSILIPELIPGVSYTVKILTQVGDGTTSLVPGWNLFCTEPEPVTSFHCEVVPKEPALVLKWACPFGMYTGFELGVRSDSWDNMTRLENCTSDDDTECRTEVAYLNFSTSYNISIATLSCGKMALPAQNICTTGITDPPTPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVILTTGEAAQPSADVLKYTYEDFKRGASDTYVTYLIRIEEKGQSQGLSEVLNYEIDVGNQSTTLGYYNGRLEPLGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVFLPQDPGVICGAVFGCIFGALAITAVGGFIFWRKKRTDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPKYTAEIAENRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRTKCEEYWPSKQAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQNSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRAQKDSKVDLIYQNTTAMTIYENLEPVSMFGKTNGYIA", "length": 1350, "header": "tr|E9Q4S7-1|PTPRJ_MOUSE Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase eta OS=Mus musculus OX=10090 GN=Ptprj PE=1 SV=2 CANONICAL=Q64455-1" }, "locus": { "chromosome": "2", "start_pos": 90410595, "end_pos": 90266757, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000168621.3", "url": "https://www.ensembl.org/id/ENSMUST00000168621.3" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000129592.3", "url": "https://www.ensembl.org/id/ENSMUSP00000129592.3" } ] } }, { "isoform_ac": "Q64455-1", "url": "", "sequence": { "sequence": "MKPAARETRTPPRSPGLRWALLPLLLLLRQGQVLCAGAAPNPIFDIEAVVSPTSVLLTWKHNDSGASECRIENKMESNLTFPVKNQTSCNITGLSPGTSYTFSIISVTTNETLNKTITTEPWPVSDLHVTSVGVTQARLTWSNANGTASYRMLIEELTTHSSVNISGLKPGTNNSFAFPESNETQADFAVAEEVPDANGTKRIPVTNLSQLHKNSLVSVDPPSGQDPSLTEILLTDLKPDTQYNATIYSQAANGTEGQPRNKVFKTNSTQVSDVRAMNISASSMTLTWKSNYDGSRTSIVYKIHVAGGTHSVNQTVNKTEAIILGLSSSTLYNITVHPFLGQTEGTPGFLQVYTSPDQVSDFRVTNVSTRAIGLAWRSNDSKSFEIFIKQDGGEKHRNASTGNQSYMVEDLKPGTSYHFEIIPRGPDGTEGLSSTVNGSTDPSAVTDIRVVNISTTEMQLEWQNTDDASGYTYHLVLESKSGSIIRTNSSQKWITVGSLTPGTLYNVTIFPEVDQIQGISNSITQYTRPSSVSHIEVNTTTTTAAIRWKNEDAASASYAYSVLILKTGDGSNVTSNFTKDPSILIPELIPGVSYTVKILTQVGDGTTSLVPGWNLFCTEPEPVTSFHCEVVPKEPALVLKWACPFGMYTGFELGVRSDSWDNMTRLENCTSDDDTECRTEVAYLNFSTSYNISIATLSCGKMALPAQNICTTGITDPPTPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVILTTGEAAQPSADVLKYTYEDFKRGASDTYVTYLIRIEEKGQSQGLSEVLNYEIDVGNQSTTLGYYNGRLEPLGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVFLPQDPGVICGAVFGCIFGALAITAVGGFIFWRKKRTDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPKYTAEIAENRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRTKCEEYWPSKQAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQNSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRAQKDSKVDLIYQNTTAMTIYENLEPVSMFGKTNGYIA", "length": 1238, "header": "sp|Q64455-1|PTPRJ_MOUSE Isoform 1 of Receptor-type tyrosine-protein phosphatase eta OS=Mus musculus OX=10090 GN=Ptprj PE=1 SV=2 CANONICAL=Q64455-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 110, "start_aa": "Asn", "end_pos": 110, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn110", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 114, "start_aa": "Asn", "end_pos": 114, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn114", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 145, "start_aa": "Asn", "end_pos": 145, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn145", "evidence": [ { "id": "2668", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2668" }, { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 145, "start_aa": "Asn", "end_pos": 145, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn145", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 164, "start_aa": "Asn", "end_pos": 164, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn164", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 173, "start_aa": "Asn", "end_pos": 173, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn173", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 182, "start_aa": "Asn", "end_pos": 182, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn182", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 198, "start_aa": "Asn", "end_pos": 198, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn198", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "G66538GV", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 207, "start_aa": "Asn", "end_pos": 207, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn207", "evidence": [ { "id": "2668", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2668" }, { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 207, "start_aa": "Asn", "end_pos": 207, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn207", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 244, "start_aa": "Asn", "end_pos": 244, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn244", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 253, "start_aa": "Asn", "end_pos": 253, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn253", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 267, "start_aa": "Asn", "end_pos": 267, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn267", "evidence": [ { "id": "2668", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2668" }, { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "glytoucan_ac": "G14669DU", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 267, "start_aa": "Asn", "end_pos": 267, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn267", "evidence": [ { "id": "2668", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2668" }, { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "glytoucan_ac": "G32550BI", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 267, "start_aa": "Asn", "end_pos": 267, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn267", "evidence": [ { "id": "2668", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2668" }, { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "glytoucan_ac": "G63628AV", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 267, "start_aa": "Asn", "end_pos": 267, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn267", "evidence": [ { "id": "2668", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2668" }, { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "glytoucan_ac": "G66538GV", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 267, "start_aa": "Asn", "end_pos": 267, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn267", "evidence": [ { "id": "2668", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2668" }, { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 267, "start_aa": "Asn", "end_pos": 267, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn267", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 278, "start_aa": "Asn", "end_pos": 278, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn278", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 313, "start_aa": "Asn", 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regulation of vascular permeability", "id": "GO:0043116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043116", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "positive regulation of focal adhesion assembly", "id": "GO:0051894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051894", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "negative regulation of platelet-derived growth factor receptor signaling pathway", "id": "GO:0010642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010642", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "negative regulation of MAP kinase activity", "id": "GO:0043407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043407", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "negative regulation of protein kinase B signaling", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "negative regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042059", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "positive chemotaxis", "id": "GO:0050918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050918", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "platelet-derived growth factor receptor signaling pathway", "id": "GO:0048008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048008", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "negative regulation of T cell receptor signaling pathway", "id": "GO:0050860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050860", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "negative regulation of signaling receptor activity", "id": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0050731", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "calcium-mediated signaling using intracellular calcium source", "id": "GO:0035584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035584", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis", "id": "GO:1905451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905451", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity", "id": "GO:1990264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990264", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "oligodendrocyte differentiation", "id": "GO:0048709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048709", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "positive regulation of cell-matrix adhesion", "id": "GO:0001954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001954", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "positive regulation of macrophage chemotaxis", "id": "GO:0010759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010759", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "positive regulation of platelet activation", "id": "GO:0010572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010572", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "Q64455", "url": "https://www.uniprot.org/uniprot/Q64455" } ], "pmid": "" }, { "name": "platelet-derived growth factor receptor binding", "id": "GO:0005161", "url": 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576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 662, "end_pos": 664, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 691, "end_pos": 693, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6P9X4-1", "O08617-1", "B4F7B7-1", "Q03348-1", "Q64346-1", "Q5FVI9-1", "P0C595-1", "Q6AXW7-1", "Q62767-1", "Q63340-1", "O54838-1", "O54857-1", "Q91XQ2-1", "Q64623-1", "Q9JIM4-1", "B2RZ50-1", "P48965-1", "P48966-1", "Q5XIS1-1", "Q62728-1", "Q62656-1", "Q63475-1", "O88488-1", "O88902-1", "P04157-1", "P81718-1", "Q64604-1", "Q64605-1", "P0C089-1", "Q641Z2-1", "B2GV87-1", "D3ZDK7-1", "P35233-1", "P35234-1", "P20417-1", "P41498-1", "P41499-2", "P49445-1", "A1L1L3-1", "Q64612-1", "A0A8I5ZV35-1", "A0A0G2K3H0-1", "A0A0G2K2N0-1", "F1LP13-1", "A0A0G2K1T5-1", "A0A8I6A1V1-1", "Q5PQT2-1", "Q62797-1", "A0A8I6AF61-1", "Q78EG7-1", "A0A0G2K8V0-1", "A0A0G2JZ01-1", "A0A8I6B402-1", "A0A0G2K9N1-1", "D3ZVI5-1", "A0A8I6GK94-1", "F1LQQ5-1", "G3V6B9-1", "Q2YDV1-1", "G3V7Q4-1", "A0A8I5ZW41-1", "G3V9S3-1", "D4ADT2-1", "P20646-1", "A0A8I6G7Q4-1", "A6HQ12-1", "Q9UMZ3-1", "P18031-1", "Q99502-1", "O75061-1", "Q9UNH5-1", "A4D256-1", "O60729-1", "Q16667-1", "P51452-1", "Q9BV47-1", "Q99504-1", "O95677-1", "Q9H596-1", "O00167-1", "Q6B8I1-1", "Q9NRW4-1", "Q16828-1", "Q4G0W2-1", "Q99956-1", "Q8NEJ0-1", "O95147-1", "P28562-1", "Q9BVJ7-1", "Q9H1R2-1", "Q9UII6-1", "Q16690-1", "Q13115-1", "Q9UNI6-1", "Q9BY84-1", "Q9Y6W6-1", "Q05923-1", "B3EWF7-1", "Q68J44-1", "Q16829-1", "Q8WTR2-1", "Q13202-1", "P30307-1", "P30304-1", "Q86V88-1", "P30305-1", "Q9NYA4-1", "Q13615-1", "Q15678-1", "Q9Y2R2-1", "P60484-1", "Q15256-1", "Q16827-1", "Q06124-2", "Q15262-1", "Q4JDL3-1", "P54829-1", "O14522-3", "P28827-1", "P35236-1", "Q99952-1", "Q05209-1", "P29350-1", "Q12913-1", "P23467-1", "P08575-3", "P18433-5", "Q9HD43-1", "P23470-1", "Q92932-1", "A6NDG6-1", "Q8WUK0-1", "P43378-1", "P23468-1", "Q16825-1", "Q9H3S7-1", "P29074-1", "P17706-1", "P26045-1", "P10586-1", "Q92729-1", "P24666-1", "P23469-1", "Q12923-1", "P23471-1", "Q13332-1", "P56180-1", "O75365-1", "Q76I76-1", "Q12974-1", "Q8TE77-1", "Q93096-1", "Q8TF42-1", "Q8WYL5-1", "P15309-1", "Q63HR2-1", "Q9Z191-1", "P97767-1", "Q80TZ3-1", "Q810P3-1", "Q6GQT0-1", "Q6PFY9-1", "Q99N11-1", "Q8BTR5-1", "Q9DBB1-1", "Q9QYJ7-1", "Q8R4V2-1", "Q8VE01-1", "Q91Z46-1", "O09112-1", "P28563-1", "Q8K4T5-1", "Q6NT99-1", "O08575-1", "Q8BK84-1", "Q8BFV3-1", "Q9WUA5-1", "Q9JLY7-1", "Q05922-1", "P97480-1", "Q9D0T2-1", "Q9D700-1", "Q9D7X3-1", "Q9D9D8-1", "Q9ESS0-1", "Q9D967-1", "P48967-1", "P30306-1", "P48964-1", "Q91XS1-1", "Q8K296-1", "Q8CHP8-1", "Q9D358-1", "P54830-1", "Q62132-1", "Q64487-4", "O70274-1", "Q9D658-1", "P29352-1", "Q62130-1", "Q63739-1", "P28828-1", "P29351-1", "Q9WU22-1", "Q8K330-1", "Q62136-1", "A2A8L5-1", "B0V2N1-1", "B2RU80-1", "B9EKR1-1", "E9Q0N2-1", "E9Q612-1", "O08586-1", "B1AUH1-1", "O35239-1", "P35831-1", "P49446-1", "P35821-1", "P35822-1", "Q8BUM3-1", "Q8BGG7-1", "A2ALK8-1", "O55082-1", "P18052-1", "Q6PB44-1", "Q64512-1", "P06800-4", "P0C5E4-1", "P35235-2", "P80560-1", "Q05909-1", "Q06180-1", "Q61152-1", "Q5SW75-1", "Q64455-1", "Q66GT5-1", "Q76I79-1", "Q99M80-1", "P70289-1", "Q7TNL7-1", "Q1HL35-1", "Q8CE08-1", "Q8CGB6-1", "A0A991ELE1-1", "P25044-1", "Q00684-1", "P29461-1", "P23748-1", "P38148-1", "P50946-1", "P38590-1", "P40048-1", "P40347-1", "P40479-1", "Q02256-1", "P40081-1", "Q12454-1", "Q54T76-1", "Q1ZXG8-1", "Q54DU9-1", "Q54R42-1", "Q55BI8-1", "Q55CS8-1", "Q55E39-1", "Q55GW2-1", "Q86IL4-1", "P34137-1", "P34138-1", "P54637-1", "Q54QM6-1", "Q54Y32-1", "Q556Y8-1", "Q55CS7-1", "Q8T9S7-1", "P82890-1", "P35832-1", "P29349-1", "P35992-5", "Q6NN85-1", "Q86BN8-1", "Q7KMQ6-1", "P82891-1", "A1ZAB3-1", "P16621-1", "O61722-1", "Q9W0G1-1", "Q03019-1", "P20483-1", "X2JEB8-1", "Q9VVW5-1", "Q05201-1", "P16620-1", "Q9VWF4-1", "Q9W4F5-1", "Q9W0R3-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-MMU-202214", "name": "Dephosphorylation of Lck-pY505 by CD45", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P06800-4", "Q64455-1", "P06240-1" ], "evidence": [ { "id": "R-MMU-202214", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-202214" } ] }, { "id": "R-MMU-202233", "name": "Inactivation of Lck by Csk", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P06800-4", "Q64455-1", "P41241-1", "P06240-1" ], "evidence": [ { "id": "R-MMU-202233", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-202233" } ] }, { "id": "R-MMU-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q64455-1", "O09005-1", "Q9Z280-1", "O35598-1", "P70704-1", "P62482-1", "B2RU80-1", "Q9Z2A7-1", "O35488-1", "A2AN08-1", "P98197-1", "Q61093-1", "O70252-1", "Q3UDW8-1", "Q80VQ0-1", "Q64277-1", "Q8K3K7-1", "Q3U435-1", "P62835-1", "O55098-1", "P61226-1", "Q05910-1", "P06869-1", "A2ANX3-1" ], "evidence": [ { "id": "R-MMU-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6799350" } ] }, { "id": "R-MMU-6807008", "name": "PTPRJ dephosphorylates MET", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q64455-1", "P16056-1" ], "evidence": [ { "id": "R-MMU-6807008", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6807008" } ] }, { "id": "R-MMU-9698408", "name": "PTPRJ dephosphorylates active FLT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q64455-1", "Q00342-1" ], "evidence": [ { "id": "R-MMU-9698408", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9698408" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0G2JZ01", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2JZ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ01" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2JZ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ01" } ] } ] }, { "uniprot_ac": "A0A0G2K1T5", "gene_name": "Eya2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K1T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K1T5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K1T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K1T5" } ] } ] }, { "uniprot_ac": "A0A0G2K2N0", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K2N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2N0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K2N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2N0" } ] } ] }, { "uniprot_ac": "A0A0G2K3H0", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K3H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K3H0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K3H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K3H0" } ] } ] }, { "uniprot_ac": "A0A0G2K8V0", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K8V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K8V0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K8V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K8V0" } ] } ] }, { "uniprot_ac": "A0A0G2K9N1", "gene_name": "Dusp13b", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] } ] }, { "uniprot_ac": "A0A8I5ZV35", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I5ZV35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV35" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I5ZV35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV35" } ] } ] }, { "uniprot_ac": "A0A8I5ZW41", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I5ZW41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZW41" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I5ZW41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZW41" } ] } ] }, { "uniprot_ac": "A0A8I6A1V1", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6A1V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1V1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6A1V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1V1" } ] } ] }, { "uniprot_ac": "A0A8I6AF61", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] } ] }, { "uniprot_ac": "A0A8I6B402", "gene_name": "Eya4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6B402", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B402" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6B402", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B402" } ] } ] }, { "uniprot_ac": "A0A8I6G7Q4", "gene_name": "AABR07036974.1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8I6G7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G7Q4" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6G7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G7Q4" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8I6G7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G7Q4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6G7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G7Q4" } ] } ] }, { "uniprot_ac": "A0A8I6GK94", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6GK94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK94" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6GK94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK94" } ] } ] }, { "uniprot_ac": "A0A991ELE1", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A991ELE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A991ELE1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A991ELE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A991ELE1" } ] } ] }, { "uniprot_ac": "A1L1L3", "gene_name": "Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A1L1L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1L1L3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A1L1L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1L1L3" } ] } ] }, { "uniprot_ac": "A1ZAB3", "gene_name": "Ptp52F", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A1ZAB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZAB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A1ZAB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZAB3" } ] } ] }, { "uniprot_ac": "A2A8L5", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2A8L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2A8L5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2A8L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2A8L5" } ] } ] }, { "uniprot_ac": "A2ALK8", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2ALK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ALK8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2ALK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ALK8" } ] } ] }, { "uniprot_ac": "A2AN08", "gene_name": "Ubr4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A2AN08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AN08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A2AN08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AN08" } ] } ] }, { "uniprot_ac": "A2ANX3", "gene_name": "Atp8b4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A2ANX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A2ANX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ] } ] }, { "uniprot_ac": "A4D256", "gene_name": "CDC14C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] } ] }, { "uniprot_ac": "A6HQ12", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] } ] }, { "uniprot_ac": "A6NDG6", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "H2O + sn-glycerol 3-phosphate = glycerol + phosphate.", "evidence": [ { "id": "A6NDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6NDG6" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6NDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6NDG6" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A6NDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6NDG6" } ] } ] }, { "uniprot_ac": "B0V2N1", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B0V2N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0V2N1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B0V2N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0V2N1" } ] } ] }, { "uniprot_ac": "B1AUH1", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B1AUH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1AUH1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B1AUH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1AUH1" } ] } ] }, { "uniprot_ac": "B2GV87", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B2GV87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GV87" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B2GV87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GV87" } ] } ] }, { "uniprot_ac": "B2RU80", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B2RU80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RU80" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B2RU80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RU80" } ] } ] }, { "uniprot_ac": "B2RZ50", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] } ] }, { "uniprot_ac": "B3EWF7", "gene_name": "EPM2A", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] } ] }, { "uniprot_ac": "B4F7B7", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] } ] }, { "uniprot_ac": "B9EKR1", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B9EKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B9EKR1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B9EKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B9EKR1" } ] } ] }, { "uniprot_ac": "D3ZDK7", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "H2O + sn-glycerol 3-phosphate = glycerol + phosphate.", "evidence": [ { "id": "D3ZDK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDK7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZDK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDK7" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "D3ZDK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDK7" } ] } ] }, { "uniprot_ac": "D3ZVI5", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZVI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZVI5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "D3ZVI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZVI5" } ] } ] }, { "uniprot_ac": "D4ADT2", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "D4ADT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ADT2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "D4ADT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ADT2" } ] } ] }, { "uniprot_ac": "E9Q0N2", "gene_name": "Ptprh", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E9Q0N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q0N2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E9Q0N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q0N2" } ] } ] }, { "uniprot_ac": "E9Q612", "gene_name": "Ptpro", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E9Q612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q612" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E9Q612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q612" } ] } ] }, { "uniprot_ac": "F1LP13", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1LP13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP13" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1LP13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP13" } ] } ] }, { "uniprot_ac": "F1LQQ5", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1LQQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LQQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1LQQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LQQ5" } ] } ] }, { "uniprot_ac": "G3V6B9", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3V6B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6B9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3V6B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6B9" } ] } ] }, { "uniprot_ac": "G3V7Q4", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3V7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V7Q4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3V7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V7Q4" } ] } ] }, { "uniprot_ac": "G3V9S3", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3V9S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V9S3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3V9S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V9S3" } ] } ] }, { "uniprot_ac": "O00167", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O00167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00167" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O00167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00167" } ] } ] }, { "uniprot_ac": "O08575", "gene_name": "Eya2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O08575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08575" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O08575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08575" } ] } ] }, { "uniprot_ac": "O08586", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] } ] }, { "uniprot_ac": "O08617", "gene_name": "Ptprr", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O08617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08617" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O08617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08617" } ] } ] }, { "uniprot_ac": "O09005", "gene_name": "Degs1", "activity": [ { "ec_number": "1.14.19.17", "activity": "an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O.", "evidence": [ { "id": "O09005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09005" } ] }, { "ec_number": "5.2.1.-", "activity": "", "evidence": [ { "id": "O09005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09005" } ] }, { "ec_number": "1.14.19.17", "activity": "", "evidence": [ { "id": "O09005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09005" } ] } ] }, { "uniprot_ac": "O09112", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] } ] }, { "uniprot_ac": "O14522", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O14522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14522" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O14522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14522" } ] } ] }, { "uniprot_ac": "O35239", "gene_name": "Ptpn9", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O35239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35239" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O35239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35239" } ] } ] }, { "uniprot_ac": "O35488", "gene_name": "Slc27a2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] }, { "ec_number": "6.2.1.-", "activity": "", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] }, { "ec_number": "6.2.1.7", "activity": "(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + ATP + CoA = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] }, { "ec_number": "6.2.1.24", "activity": "3,7,11,15-tetramethylhexadecanoate + ATP + CoA = AMP + diphosphate + phytanoyl-CoA.", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] }, { "ec_number": "6.2.1.15", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] } ] }, { "uniprot_ac": "O35598", "gene_name": "Adam10", "activity": [ { "ec_number": "3.4.24.81", "activity": "Endopeptidase of broad specificity.", "evidence": [ { "id": "O35598", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35598" } ] }, { "ec_number": "3.4.24.81", "activity": "", "evidence": [ { "id": "O35598", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35598" } ] } ] }, { "uniprot_ac": "O54838", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] } ] }, { "uniprot_ac": "O54857", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] } ] }, { "uniprot_ac": "O55082", "gene_name": "Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O55082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55082" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O55082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55082" } ] } ] }, { "uniprot_ac": "O55098", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] } ] }, { "uniprot_ac": "O60729", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] } ] }, { "uniprot_ac": "O61722", "gene_name": "PRL-1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O61722", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61722" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O61722", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61722" } ] } ] }, { "uniprot_ac": "O70252", "gene_name": "Hmox2", "activity": [ { "ec_number": "1.14.14.18", "activity": "heme b + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = biliverdin IXalpha + CO + Fe(2+) + H(+) + 3 H2O + 3 oxidized [NADPH--hemoprotein reductase].", "evidence": [ { "id": "O70252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70252" } ] }, { "ec_number": "1.14.14.18", "activity": "", "evidence": [ { "id": "O70252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70252" } ] } ] }, { "uniprot_ac": "O70274", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O70274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70274" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O70274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70274" } ] } ] }, { "uniprot_ac": "O75061", "gene_name": "DNAJC6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O75061", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75061" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O75061", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75061" } ] } ] }, { "uniprot_ac": "O75365", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O75365", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75365" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O75365", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75365" } ] } ] }, { "uniprot_ac": "O88488", "gene_name": "Ptprq", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O88488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88488" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O88488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88488" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "O88488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88488" } ] } ] }, { "uniprot_ac": "O88902", "gene_name": "Ptpn23", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O88902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88902" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O88902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88902" } ] } ] }, { "uniprot_ac": "O95147", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] } ] }, { "uniprot_ac": "O95677", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O95677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95677" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O95677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95677" } ] } ] }, { "uniprot_ac": "P04157", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P04157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04157" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P04157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04157" } ] } ] }, { "uniprot_ac": "P06240", "gene_name": "Lck", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P06240", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06240" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P06240", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06240" } ] } ] }, { "uniprot_ac": "P06800", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P06800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06800" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P06800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06800" } ] } ] }, { "uniprot_ac": "P06869", "gene_name": "Plau", "activity": [ { "ec_number": "3.4.21.73", "activity": "Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.", "evidence": [ { "id": "P06869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06869" } ] }, { "ec_number": "3.4.21.73", "activity": "", "evidence": [ { "id": "P06869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06869" } ] } ] }, { "uniprot_ac": "P08575", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P08575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08575" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P08575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08575" } ] } ] }, { "uniprot_ac": "P0C089", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] } ] }, { "uniprot_ac": "P0C595", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] } ] }, { "uniprot_ac": "P0C5E4", "gene_name": "Ptprq", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "P0C5E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5E4" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C5E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5E4" } ] } ] }, { "uniprot_ac": "P10586", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P10586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10586" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P10586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10586" } ] } ] }, { "uniprot_ac": "P15309", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "P15309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15309" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P15309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15309" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P15309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15309" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "P15309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15309" } ] } ] }, { "uniprot_ac": "P16056", "gene_name": "Met", "activity": [ { "ec_number": "2.7.10.1", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16056" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16056" } ] } ] }, { "uniprot_ac": "P16620", "gene_name": "Ptp69D", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P16620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16620" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P16620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16620" } ] } ] }, { "uniprot_ac": "P16621", "gene_name": "Lar", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P16621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16621" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P16621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16621" } ] } ] }, { "uniprot_ac": "P17706", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P17706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17706" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P17706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17706" } ] } ] }, { "uniprot_ac": "P18031", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P18031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18031" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P18031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18031" } ] } ] }, { "uniprot_ac": "P18052", "gene_name": "Ptpra", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P18052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18052" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P18052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18052" } ] } ] }, { "uniprot_ac": "P18433", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P18433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18433" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P18433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18433" } ] } ] }, { "uniprot_ac": "P20417", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P20417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20417" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P20417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20417" } ] } ] }, { "uniprot_ac": "P20483", "gene_name": "stg", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P20483", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20483" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P20483", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20483" } ] } ] }, { "uniprot_ac": "P20646", "gene_name": "Acp3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "P20646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20646" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P20646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20646" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P20646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20646" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "P20646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20646" } ] } ] }, { "uniprot_ac": "P23467", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23467" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23467" } ] } ] }, { "uniprot_ac": "P23468", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23468" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23468" } ] } ] }, { "uniprot_ac": "P23469", "gene_name": "PTPRE", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23469" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23469" } ] } ] }, { "uniprot_ac": "P23470", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23470" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23470" } ] } ] }, { "uniprot_ac": "P23471", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23471", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23471" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23471", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23471" } ] } ] }, { "uniprot_ac": "P23748", "gene_name": "MIH1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23748" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23748" } ] } ] }, { "uniprot_ac": "P24666", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P24666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24666" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "P24666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24666" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P24666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24666" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P24666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24666" } ] } ] }, { "uniprot_ac": "P25044", "gene_name": "PTP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P25044", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25044" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P25044", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25044" } ] } ] }, { "uniprot_ac": "P26045", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P26045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26045" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P26045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26045" } ] } ] }, { "uniprot_ac": "P28562", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] } ] }, { "uniprot_ac": "P28563", "gene_name": "Dusp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] } ] }, { "uniprot_ac": "P28827", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28827" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28827" } ] }, { "ec_number": "2.7.10.1", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P28827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28827" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28827" } ] } ] }, { "uniprot_ac": "P28828", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28828", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28828" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28828", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28828" } ] } ] }, { "uniprot_ac": "P29074", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29074" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29074" } ] } ] }, { "uniprot_ac": "P29349", "gene_name": "csw", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29349" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29349" } ] } ] }, { "uniprot_ac": "P29350", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29350" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29350" } ] } ] }, { "uniprot_ac": "P29351", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29351" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29351" } ] } ] }, { "uniprot_ac": "P29352", "gene_name": "Ptpn22", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29352" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29352" } ] } ] }, { "uniprot_ac": "P29461", "gene_name": "PTP2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29461" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29461" } ] } ] }, { "uniprot_ac": "P30304", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P30304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30304" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P30304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30304" } ] } ] }, { "uniprot_ac": "P30305", "gene_name": "CDC25B", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P30305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30305" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P30305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30305" } ] } ] }, { "uniprot_ac": "P30306", "gene_name": "Cdc25b", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P30306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30306" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P30306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30306" } ] } ] }, { "uniprot_ac": "P30307", "gene_name": "CDC25C", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P30307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30307" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P30307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30307" } ] } ] }, { "uniprot_ac": "P34137", "gene_name": "ptpA1-2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P34137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34137" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P34137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34137" } ] } ] }, { "uniprot_ac": "P34138", "gene_name": "ptpB", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P34138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34138" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P34138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34138" } ] } ] }, { "uniprot_ac": "P35233", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35233" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35233" } ] } ] }, { "uniprot_ac": "P35234", "gene_name": "Ptpn5", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35234" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35234" } ] } ] }, { "uniprot_ac": "P35235", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35235" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35235" } ] } ] }, { "uniprot_ac": "P35236", "gene_name": "PTPN7", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35236" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35236" } ] } ] }, { "uniprot_ac": "P35821", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35821" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35821" } ] } ] }, { "uniprot_ac": "P35822", "gene_name": "Ptprk", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35822" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35822" } ] } ] }, { "uniprot_ac": "P35831", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35831" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35831" } ] } ] }, { "uniprot_ac": "P35832", "gene_name": "Ptp99A", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35832" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35832" } ] } ] }, { "uniprot_ac": "P35992", "gene_name": "Ptp10D", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35992" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35992" } ] } ] }, { "uniprot_ac": "P38148", "gene_name": "PPS1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] } ] }, { "uniprot_ac": "P38590", "gene_name": "MSG5", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P38590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38590" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P38590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38590" } ] } ] }, { "uniprot_ac": "P40048", "gene_name": "PTP3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P40048", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40048" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P40048", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40048" } ] } ] }, { "uniprot_ac": "P40081", "gene_name": "", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P40081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40081" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P40081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40081" } ] } ] }, { "uniprot_ac": "P40347", "gene_name": "LTP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P40347", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40347" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P40347", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40347" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P40347", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40347" } ] } ] }, { "uniprot_ac": "P40479", "gene_name": "SDP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P40479", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40479" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P40479", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40479" } ] } ] }, { "uniprot_ac": "P41241", "gene_name": "Csk", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P41241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41241" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P41241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41241" } ] } ] }, { "uniprot_ac": "P41498", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P41498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41498" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P41498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41498" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P41498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41498" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "P41498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41498" } ] } ] }, { "uniprot_ac": "P41499", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P41499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41499" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P41499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41499" } ] } ] }, { "uniprot_ac": "P43378", "gene_name": "PTPN9", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P43378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43378" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P43378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43378" } ] } ] }, { "uniprot_ac": "P48964", "gene_name": "Cdc25a", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P48964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48964" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P48964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48964" } ] } ] }, { "uniprot_ac": "P48965", "gene_name": "Cdc25a", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P48965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48965" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P48965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48965" } ] } ] }, { "uniprot_ac": "P48966", "gene_name": "Cdc25b", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P48966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48966" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P48966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48966" } ] } ] }, { "uniprot_ac": "P48967", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P48967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48967" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P48967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48967" } ] } ] }, { "uniprot_ac": "P49445", "gene_name": "Ptpn7", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P49445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49445" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P49445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49445" } ] } ] }, { "uniprot_ac": "P49446", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P49446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49446" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P49446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49446" } ] } ] }, { "uniprot_ac": "P50946", "gene_name": "OCA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P50946", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50946" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P50946", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50946" } ] } ] }, { "uniprot_ac": "P51452", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] } ] }, { "uniprot_ac": "P54637", "gene_name": "ptpC", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P54637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54637" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P54637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54637" } ] } ] }, { "uniprot_ac": "P54829", "gene_name": "PTPN5", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P54829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54829" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P54829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54829" } ] } ] }, { "uniprot_ac": "P54830", "gene_name": "Ptpn5", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P54830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54830" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P54830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54830" } ] } ] }, { "uniprot_ac": "P56180", "gene_name": "TPTE", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P56180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P56180" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P56180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P56180" } ] } ] }, { "uniprot_ac": "P60484", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] } ] }, { "uniprot_ac": "P61226", "gene_name": "Rap2b", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P61226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P61226" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P61226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P61226" } ] } ] }, { "uniprot_ac": "P62482", "gene_name": "Kcnab2", "activity": [ { "ec_number": "1.1.1.-", "activity": "", "evidence": [ { "id": "P62482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62482" } ] } ] }, { "uniprot_ac": "P62835", "gene_name": "Rap1a", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P62835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62835" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P62835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62835" } ] } ] }, { "uniprot_ac": "P70289", "gene_name": "Ptprv", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P70289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70289" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P70289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70289" } ] } ] }, { "uniprot_ac": "P70704", "gene_name": "Atp8a1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "P70704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70704" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "P70704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70704" } ] } ] }, { "uniprot_ac": "P80560", "gene_name": "Ptprn2", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "P80560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80560" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P80560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80560" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P80560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80560" } ] } ] }, { "uniprot_ac": "P81718", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P81718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P81718" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P81718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P81718" } ] } ] }, { "uniprot_ac": "P82890", "gene_name": "primo-1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P82890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82890" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P82890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82890" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P82890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82890" } ] } ] }, { "uniprot_ac": "P82891", "gene_name": "primo-2", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P82891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82891" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P82891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82891" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P82891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82891" } ] } ] }, { "uniprot_ac": "P97480", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P97480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97480" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P97480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97480" } ] } ] }, { "uniprot_ac": "P97767", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] } ] }, { "uniprot_ac": "P98197", "gene_name": "Atp11a", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "P98197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98197" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "P98197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98197" } ] } ] }, { "uniprot_ac": "Q00342", "gene_name": "Flt3", "activity": [ { "ec_number": "2.7.10.1", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q00342", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00342" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q00342", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00342" } ] } ] }, { "uniprot_ac": "Q00684", "gene_name": "CDC14", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q00684", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00684" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q00684", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00684" } ] } ] }, { "uniprot_ac": "Q02256", "gene_name": "YVH1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q02256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q02256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02256" } ] } ] }, { "uniprot_ac": "Q03019", "gene_name": "twe", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q03019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03019" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q03019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03019" } ] } ] }, { "uniprot_ac": "Q03348", "gene_name": "Ptpra", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q03348", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03348" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q03348", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03348" } ] } ] }, { "uniprot_ac": "Q05201", "gene_name": "eya", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05201", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05201" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05201", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05201" } ] } ] }, { "uniprot_ac": "Q05209", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05209" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05209" } ] } ] }, { "uniprot_ac": "Q05909", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05909" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05909" } ] } ] }, { "uniprot_ac": "Q05910", "gene_name": "Adam8", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q05910", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05910" } ] } ] }, { "uniprot_ac": "Q05922", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q05922", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05922" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05922", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05922" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q05922", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05922" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05922", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05922" } ] } ] }, { "uniprot_ac": "Q05923", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q05923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05923" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05923" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05923" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q05923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05923" } ] } ] }, { "uniprot_ac": "Q06124", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q06124", "database": "UniProtKB", "url": 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"", "evidence": [ { "id": "Q13115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13115" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q13115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13115" } ] } ] }, { "uniprot_ac": "Q13202", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q13202", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13202" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q13202", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13202" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q13202", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13202" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q13202", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13202" } ] } ] }, { "uniprot_ac": "Q13332", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q13332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13332" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q13332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13332" } ] } ] }, { "uniprot_ac": "Q13615", "gene_name": "MTMR3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] }, { "ec_number": "3.1.3.64", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate.", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] }, { "ec_number": "3.1.3.64", "activity": "", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] }, { "ec_number": "3.1.3.95", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate.", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] } ] }, { "uniprot_ac": "Q15256", "gene_name": "PTPRR", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q15256", "database": "UniProtKB", "url": 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"id": "Q15678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15678" } ] } ] }, { "uniprot_ac": "Q16667", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q16667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16667" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q16667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16667" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q16667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16667" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q16667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16667" } ] } ] }, { "uniprot_ac": "Q16690", "gene_name": "DUSP5", "activity": [ { 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"url": "https://www.uniprot.org/uniprot/Q16825" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q16825", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16825" } ] } ] }, { "uniprot_ac": "Q16827", "gene_name": "PTPRO", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q16827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16827" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q16827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16827" } ] } ] }, { "uniprot_ac": "Q16828", "gene_name": "DUSP6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q16828", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16828" } ] }, { "ec_number": "3.1.3.48", "activity": "", 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"https://www.uniprot.org/uniprot/Q4G0W2" } ] } ] }, { "uniprot_ac": "Q4JDL3", "gene_name": "PTPN20", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q4JDL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4JDL3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q4JDL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4JDL3" } ] } ] }, { "uniprot_ac": "Q54DU9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q54DU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DU9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q54DU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DU9" } ] } ] }, { "uniprot_ac": "Q54QM6", "gene_name": "cdc25", "activity": 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"url": "https://www.uniprot.org/uniprot/Q54R42" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q54R42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R42" } ] } ] }, { "uniprot_ac": "Q54T76", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q54T76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54T76" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q54T76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54T76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q54T76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54T76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q54T76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54T76" } ] } ] }, { "uniprot_ac": "Q54Y32", "gene_name": "mpl3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q54Y32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y32" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q54Y32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q54Y32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y32" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q54Y32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y32" } ] } ] }, { "uniprot_ac": "Q556Y8", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q556Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556Y8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q556Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556Y8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q556Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556Y8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q556Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556Y8" } ] } ] }, { "uniprot_ac": "Q55BI8", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q55BI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55BI8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q55BI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55BI8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q55BI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55BI8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q55BI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55BI8" } ] } ] }, { "uniprot_ac": "Q55CS7", "gene_name": "mpl1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q55CS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CS7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q55CS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CS7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q55CS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CS7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q55CS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CS7" } ] } ] }, { "uniprot_ac": "Q55CS8", "gene_name": "mpl2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q55CS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CS8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q55CS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CS8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q55CS8", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprot/Q55E39" } ] } ] }, { "uniprot_ac": "Q55GW2", "gene_name": "acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q55GW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GW2" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q55GW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GW2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q55GW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GW2" } ] } ] }, { "uniprot_ac": "Q5FVI9", "gene_name": "Dusp26", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5FVI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FVI9" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5FVI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FVI9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5FVI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FVI9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5FVI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FVI9" } ] } ] }, { "uniprot_ac": "Q5PQT2", "gene_name": "Mtmr3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] }, { "ec_number": "3.1.3.64", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate.", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] }, { "ec_number": "3.1.3.64", "activity": "", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] }, { "ec_number": "3.1.3.95", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate.", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] } ] }, { "uniprot_ac": "Q5SW75", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5SW75", "database": "UniProtKB", "url": 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} ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q62767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62767" } ] } ] }, { "uniprot_ac": "Q62797", "gene_name": "Ptpro", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q62797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62797" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q62797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62797" } ] } ] }, { "uniprot_ac": "Q63340", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q63340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63340" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + 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"https://www.uniprot.org/uniprot/Q63475" } ] } ] }, { "uniprot_ac": "Q63739", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q63739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63739" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q63739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63739" } ] } ] }, { "uniprot_ac": "Q63HR2", "gene_name": "TNS2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q63HR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63HR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q63HR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63HR2" } ] } ] }, { "uniprot_ac": "Q641Z2", "gene_name": "Ptpn9", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q641Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q641Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z2" } ] } ] }, { "uniprot_ac": "Q64277", "gene_name": "Bst1", "activity": [ { "ec_number": "3.2.2.6", "activity": "H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide.", "evidence": [ { "id": "Q64277", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64277" } ] }, { "ec_number": "3.2.2.6", "activity": "", "evidence": [ { "id": "Q64277", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64277" } ] } ] }, { "uniprot_ac": "Q64346", "gene_name": "Dusp6", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] } ] }, { "uniprot_ac": "Q64455", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455" } ] } ] }, { "uniprot_ac": "Q64487", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64487" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64487" } ] } ] }, { "uniprot_ac": "Q64512", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64512" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64512" } ] } ] }, { "uniprot_ac": "Q64604", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64604", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64604" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64604", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64604" } ] } ] }, { "uniprot_ac": "Q64605", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64605" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64605" } ] } ] }, { "uniprot_ac": "Q64612", "gene_name": "Ptprv", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64612" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64612" } ] } ] }, { "uniprot_ac": "Q64623", "gene_name": "Dusp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q64623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64623" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64623" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q64623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64623" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64623" } ] } ] }, { "uniprot_ac": "Q66GT5", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q66GT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66GT5" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "Q66GT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66GT5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q66GT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66GT5" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "Q66GT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66GT5" } ] } ] }, { "uniprot_ac": "Q68J44", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q68J44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q68J44" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q68J44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q68J44" } ] } ] }, { "uniprot_ac": "Q6AXW7", "gene_name": "Dusp18", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6AXW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6AXW7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6AXW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6AXW7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6AXW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6AXW7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6AXW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6AXW7" } ] } ] }, { "uniprot_ac": "Q6B8I1", "gene_name": "DUSP13A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6B8I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B8I1" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6B8I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B8I1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6B8I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B8I1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6B8I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B8I1" } ] } ] }, { "uniprot_ac": "Q6GQT0", "gene_name": "Cdc14a", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6GQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6GQT0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6GQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6GQT0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6GQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6GQT0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6GQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6GQT0" } ] } ] }, { "uniprot_ac": "Q6NN85", "gene_name": "ssh", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NN85" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NN85" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NN85" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NN85" } ] } ] }, { "uniprot_ac": "Q6NT99", "gene_name": "Dusp23", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NT99" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NT99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6NT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NT99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6NT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NT99" } ] } ] }, { "uniprot_ac": "Q6P9X4", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6P9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P9X4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6P9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P9X4" } ] } ] }, { "uniprot_ac": "Q6PB44", "gene_name": "Ptpn23", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6PB44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PB44" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6PB44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PB44" } ] } ] }, { "uniprot_ac": "Q6PFY9", "gene_name": "Cdc14b", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6PFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PFY9" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6PFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PFY9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6PFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PFY9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6PFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PFY9" } ] } ] }, { "uniprot_ac": "Q76I76", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q76I76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q76I76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I76" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q76I76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q76I76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I76" } ] } ] }, { "uniprot_ac": "Q76I79", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q76I79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I79" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q76I79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I79" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q76I79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I79" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q76I79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I79" } ] } ] }, { "uniprot_ac": "Q78EG7", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q78EG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q78EG7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q78EG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q78EG7" } ] } ] }, { "uniprot_ac": "Q7KMQ6", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] }, { "ec_number": "3.1.3.64", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate.", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] } ] }, { "uniprot_ac": "Q7TNL7", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] } ] }, { "uniprot_ac": "Q80TZ3", "gene_name": "Dnajc6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q80TZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80TZ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q80TZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80TZ3" } ] } ] }, { "uniprot_ac": "Q80VQ0", "gene_name": "Aldh3b1", "activity": [ { "ec_number": "1.2.1.5", "activity": "an aldehyde + H2O + NAD(+) = a carboxylate + 2 H(+) + NADH.", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.28", "activity": "benzaldehyde + H2O + NAD(+) = benzoate + 2 H(+) + NADH.", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.7", "activity": "benzaldehyde + H2O + NADP(+) = benzoate + 2 H(+) + NADPH.", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.7", "activity": "", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.5", "activity": "", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.28", "activity": "", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] } ] }, { "uniprot_ac": "Q810P3", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] } ] }, { "uniprot_ac": "Q86BN8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] } ] }, { "uniprot_ac": "Q86IL4", "gene_name": "", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q86IL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IL4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q86IL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IL4" } ] } ] }, { "uniprot_ac": "Q86V88", "gene_name": "MDP1", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q86V88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V88" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q86V88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q86V88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V88" } ] } ] }, { "uniprot_ac": "Q8BFV3", "gene_name": "Dusp4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] } ] }, { "uniprot_ac": "Q8BGG7", "gene_name": "Ubash3b", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BGG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGG7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BGG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGG7" } ] } ] }, { "uniprot_ac": "Q8BK84", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK84" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK84" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK84" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK84" } ] } ] }, { "uniprot_ac": "Q8BTR5", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTR5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTR5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTR5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTR5" } ] } ] }, { "uniprot_ac": "Q8BUM3", "gene_name": "Ptpn7", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BUM3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BUM3" } ] } ] }, { "uniprot_ac": "Q8CE08", "gene_name": "Acp3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "Q8CE08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE08" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q8CE08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE08" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CE08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE08" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "Q8CE08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE08" } ] } ] }, { "uniprot_ac": "Q8CGB6", "gene_name": "Tns2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CGB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CGB6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8CGB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CGB6" } ] } ] }, { "uniprot_ac": "Q8CHP8", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "H2O + sn-glycerol 3-phosphate = glycerol + phosphate.", "evidence": [ { "id": "Q8CHP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHP8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CHP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHP8" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "Q8CHP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHP8" } ] } ] }, { "uniprot_ac": "Q8K296", "gene_name": "Mtmr3", "activity": [ { "ec_number": "3.1.3.64", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate.", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] }, { "ec_number": "3.1.3.64", "activity": "", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] }, { "ec_number": "3.1.3.95", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate.", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] } ] }, { "uniprot_ac": "Q8K330", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] } ] }, { "uniprot_ac": "Q8K3K7", "gene_name": "Agpat2", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "Q8K3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K3K7" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "Q8K3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K3K7" } ] } ] }, { "uniprot_ac": "Q8K4T5", "gene_name": "Dusp19", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] } ] }, { "uniprot_ac": "Q8NEJ0", "gene_name": "DUSP18", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] } ] }, { "uniprot_ac": "Q8R4V2", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] } ] }, { "uniprot_ac": "Q8T9S7", "gene_name": "pteN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] } ] }, { "uniprot_ac": "Q8TE77", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] } ] }, { "uniprot_ac": "Q8TF42", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8TF42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF42" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8TF42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF42" } ] } ] }, { "uniprot_ac": "Q8VE01", "gene_name": "Dusp18", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": 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O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] } ] }, { "uniprot_ac": "Q8WYL5", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = 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"evidence": [ { "id": "Q91XS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XS1" } ] } ] }, { "uniprot_ac": "Q91Z46", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q91Z46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z46" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q91Z46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z46" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q91Z46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z46" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q91Z46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z46" } ] } ] }, { "uniprot_ac": "Q92729", "gene_name": "PTPRU", 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