{ "uniprot_canonical_ac": "Q62950-1", "uniprot_ac": "Q62950", "uniprot_id": "DPYL1_RAT", "mass": { "chemical_mass": 62196.0, "monoisotopic_mass": 62196.0 }, "refseq": { "ac": "NP_037064", "name": "dihydropyrimidinase-related protein 1 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064" }, "gene_names": [ { "name": "Crmp1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q62950", "id": "Q62950" }, { "name": "Dpysl1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q62950", "id": "Q62950" } ], "protein_names": [ { "name": "Dihydropyrimidinase-related protein 1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q62950" }, { "name": "CRMP-1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q62950" }, { "name": "Collapsin response mediator protein 1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q62950" }, { "name": "DRP-1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q62950" }, { "name": "Inactive dihydropyrimidinase", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q62950" }, { "name": "dihydropyrimidinase-related protein 1 isoform 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064", "id": "NP_037064" }, { "name": "dihydropyrimidinase-related protein 1; DRP-1; CRMP-1; inactive dihydropyrimidinase", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064", "id": "NP_037064" } ], "function": [ { "annotation": "Data link the reduction in PMCA2 expression with perturbations in CRMP1 expression and death of spinal cord neurons, representing an additional mechanism underlying AMPA/kainate receptor-mediated excitotoxicity with relevance to neurodegeneration in EAE.", "evidence": [ { "database": "RefSeq", "id": "NP_037064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064" }, { "database": "PubMed", "id": "20489728", "url": "https://glygen.org/publication/PubMed/20489728" } ] }, { "annotation": "FEZ1 Forms Complexes with CRMP1 and DCC to Regulate Axon and Dendrite Development. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_037064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064" }, { "database": "PubMed", "id": "33771901", "url": "https://glygen.org/publication/PubMed/33771901" } ] }, { "annotation": "High sugar but not high fat diet consumption induces hepatic metabolic disruption and up-regulation of mitochondrial fission-associated protein Drp1 in a model of moderate obesity.", "evidence": [ { "database": "RefSeq", "id": "NP_037064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064" }, { "database": "PubMed", "id": "32880477", "url": "https://glygen.org/publication/PubMed/32880477" } ] }, { "annotation": "Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Plays a role in axon guidance (By similarity). During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone (By similarity). Involved in invasive growth and cell migration. May participate in cytokinesis (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950#function" }, { "database": "UniProtKB", "id": "Q14194", "url": "https://www.uniprot.org/uniprot/Q14194#function" }, { "database": "UniProtKB", "id": "P97427", "url": "https://www.uniprot.org/uniprot/P97427#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "common_name": "Rat" } ], "gene": [ { "name": "Crmp1", "url": "https://www.uniprot.org/uniprot/Q62950", "locus": { "chromosome": "14", "start_pos": 73509933, "end_pos": 73556177, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000004781", "url": "https://www.ensembl.org/id/ENSRNOG00000004781" } ] } } ], "crossref": [ { "id": "ENSRNOG00000004781", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000004781", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01314", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01314", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "25415", "url": "https://www.ncbi.nlm.nih.gov/gene/25415", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q62950", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q62950*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR006680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:25415", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:25415", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q62950", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62950", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "HICHVSH", "url": "https://omabrowser.org/oma/group/HICHVSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "1772494at2759", "url": "http://www.orthodb.org/?query=1772494at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11647", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11647", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11647:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11647:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01979", "url": "http://pfam.xfam.org/family/PF01979", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q62950", "url": "http://purl.obolibrary.org/obo/PR_Q62950", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-RNO-399956", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-399956", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_037064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "2407", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=2407", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A8I6A2Y7", "url": "https://www.uniprot.org/uniprot/A0A8I6A2Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A2Y7-1", "url": "https://www.uniprot.org/uniprot/A0A8I6A2Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6ALU3", "url": "https://www.uniprot.org/uniprot/A0A8I6ALU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6ALU3-1", "url": "https://www.uniprot.org/uniprot/A0A8I6ALU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6ANJ3", "url": "https://www.uniprot.org/uniprot/A0A8I6ANJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6ANJ3-1", "url": "https://www.uniprot.org/uniprot/A0A8I6ANJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q62950-1", "url": "https://www.uniprot.org/uniprot/Q62950-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHQGKKSIPHITSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTRAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTLTAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "length": 572, "header": "sp|Q62950-1|DPYL1_RAT Isoform 1 of Dihydropyrimidinase-related protein 1 OS=Rattus norvegicus OX=10116 GN=Crmp1 PE=1 SV=1 CANONICAL=Q62950-1" }, "isoforms": [ { "isoform_ac": "A0A8I6A2Y7-1", "url": "", "sequence": { "sequence": "MAERRRAWNTEDDLPVYLARPGSAAQTPRQKYGGMFAAVEGAYENKTIDFDAYSVGRRGSARTPRSAGRPDAVGLPCPGGSEDTASDVSEPSGSAVSSPGDRDDRPPALRIRCPAPRDLPLGRDNGQSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTRAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTLTAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "length": 686, "header": "tr|A0A8I6A2Y7-1|A0A8I6A2Y7_RAT Computationally mapped isoform of Collapsin response mediator protein 1 OS=Rattus norvegicus OX=10116 GN=Crmp1 PE=1 SV=1 CANONICAL=Q62950-1" }, "locus": { "chromosome": "14", "start_pos": 73556083, "end_pos": 73510850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000106933.1", "url": "https://www.ensembl.org/id/ENSRNOT00000106933.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000086765.1", "url": "https://www.ensembl.org/id/ENSRNOP00000086765.1" } ] } }, { "isoform_ac": "A0A8I6ALU3-1", "url": "", "sequence": { "sequence": "MQFPTAAFAEGTNLILTLWEESRTPWESDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTRAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTLTAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "length": 586, "header": "tr|A0A8I6ALU3-1|DPYL1_RAT Computationally mapped isoform of Dihydropyrimidinase-related protein 1 OS=Rattus norvegicus OX=10116 GN=Crmp1 PE=1 SV=1 CANONICAL=Q62950-1" }, "locus": { "chromosome": "14", "start_pos": 73539871, "end_pos": 73510850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000119459.1", "url": "https://www.ensembl.org/id/ENSRNOT00000119459.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000094296.1", "url": "https://www.ensembl.org/id/ENSRNOP00000094296.1" } ] } }, { "isoform_ac": "A0A8I6ANJ3-1", "url": "", "sequence": { "sequence": "MSGSHEGGASIGSGSSSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTRAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQVASIHERGDPPAWEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTLTAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "length": 561, "header": "tr|A0A8I6ANJ3-1|A0A8I6ANJ3_RAT Computationally mapped isoform of Collapsin response mediator protein 1 OS=Rattus norvegicus OX=10116 GN=Crmp1 PE=1 SV=1 CANONICAL=Q62950-1" }, "locus": { "chromosome": "14", "start_pos": 73532936, "end_pos": 73510850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000108366.1", "url": "https://www.ensembl.org/id/ENSRNOT00000108366.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000094585.1", "url": "https://www.ensembl.org/id/ENSRNOP00000094585.1" } ] } }, { "isoform_ac": "Q62950-1", "url": "", "sequence": { "sequence": "MSHQGKKSIPHITSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTRAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTLTAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "length": 572, "header": "sp|Q62950-1|DPYL1_RAT Isoform 1 of Dihydropyrimidinase-related protein 1 OS=Rattus norvegicus OX=10116 GN=Crmp1 PE=1 SV=1 CANONICAL=Q62950-1" }, "locus": { "chromosome": "14", "start_pos": 73552130, "end_pos": 73510850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000065334", "url": "https://www.ensembl.org/id/ENSRNOT00000065334" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000063671", "url": "https://www.ensembl.org/id/ENSRNOP00000063671" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "Q62950", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62950" }, { "id": "18683930", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18683930" } ] } ], "phosphorylation": [ { "start_pos": 101, "end_pos": 101, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "site_lbl": "Thr101" }, { "start_pos": 102, "end_pos": 102, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "site_lbl": "Thr102" }, { "start_pos": 504, "end_pos": 504, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "site_lbl": "Tyr504" }, { "start_pos": 509, "end_pos": 509, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "site_lbl": "Thr509" }, { "start_pos": 521, "end_pos": 521, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "Q62950", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62950" } ], "site_lbl": "Ser521" }, { "start_pos": 522, "end_pos": 522, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "Q62950", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62950" } ], "site_lbl": "Ser522" }, { "start_pos": 537, "end_pos": 537, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "site_lbl": "Ser537" }, { "start_pos": 540, "end_pos": 540, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "site_lbl": "Ser540" }, { "start_pos": 542, "end_pos": 542, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "site_lbl": "Ser542" }, { "start_pos": 8, "end_pos": 8, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "Q62950", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62950" } ], "site_lbl": "Ser8" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Direct in-gel fluorescence detection and cellular imaging of O-GlcNAc-modified proteins.", "journal": "Journal of the American Chemical Society", "date": "2008", "authors": "Clark PM, Dweck JF, Mason DE, Hart CR, Buck SB, Peters EC, Agnew BJ, Hsieh-Wilson LC", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q62950", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q62950" } ], "reference": [ { "type": "PubMed", "id": "18683930", "url": "https://glygen.org/publication/PubMed/18683930" } ] }, { "title": "Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons.", "journal": "Cell death and differentiation", "date": "2010", "authors": "Kurnellas MP, Li H, Jain MR, Giraud SN, Nicot AB, Ratnayake A, Heary RF, Elkabes S", "evidence": [ { "database": "RefSeq", "id": "NP_037064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064" } ], "reference": [ { "type": "PubMed", "id": "20489728", "url": "https://glygen.org/publication/PubMed/20489728" } ] }, { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nature communications", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" }, { "database": "iPTMnet", "id": "Q62950", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q62950" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "title": "Amino- and carboxyl-terminal domains of Filamin-A interact with CRMP1 to mediate Sema3A signalling.", "journal": "Nat. Commun.", "date": "2014", "authors": "Nakamura F, Kumeta K, Hida T, Isono T, Nakayama Y, Kuramata-Matsuoka E, Yamashita N, Uchida Y, Ogura K, Gengyo-Ando K, Mitani S, Ogino T, Goshima Y", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "reference": [ { "type": "PubMed", "id": "25358863", "url": "https://glygen.org/publication/PubMed/25358863" } ] }, { "title": "High sugar but not high fat diet consumption induces hepatic metabolic disruption and up-regulation of mitochondrial fission-associated protein Drp1 in a model of moderate obesity.", "journal": "Archives of physiology and biochemistry", "date": "2020-09-03", "authors": "Cruz Hern\u00e1ndez Jarumi Hishel, Rosado Lom\u00e1n Wendy Natalia, G\u00f3mez-Cris\u00f3stomo Nancy Patricia, De la Cruz-Hern\u00e1ndez Erick Natividad, Guzm\u00e1n Garc\u00eda Luz Mar\u00eda, G\u00f3mez G\u00f3mez Montserrat, Hern\u00e1ndez Del \u00c1ngel Nadia Arely, Aguilar Gamas Carlos Francisco, Cruz Hern\u00e1ndez Vania Sherel, Martinez-Abundis Eduardo", "evidence": [ { "database": "RefSeq", "id": "NP_037064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064" } ], "reference": [ { "type": "PubMed", "id": "32880477", "url": "https://glygen.org/publication/PubMed/32880477" } ] }, { "title": "FEZ1 Forms Complexes with CRMP1 and DCC to Regulate Axon and Dendrite Development.", "journal": "eNeuro", "date": "2021", "authors": "Chua JY, Ng SJ, Yagensky O, Wanker EE, Chua JJE", "evidence": [ { "database": "RefSeq", "id": "NP_037064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037064" } ], "reference": [ { "type": "PubMed", "id": "33771901", "url": "https://glygen.org/publication/PubMed/33771901" } ] }, { "title": "A family of rat CRMP genes is differentially expressed in the nervous system.", "journal": "J. Neurosci.", "date": "1996", "authors": "Wang LH, Strittmatter SM", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "reference": [ { "type": "PubMed", "id": "8815901", "url": "https://glygen.org/publication/PubMed/8815901" } ] }, { "title": "Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase.", "journal": "J. Neurochem.", "date": "1997", "authors": "Wang LH, Strittmatter SM", "evidence": [ { "database": "UniProtKB", "id": "Q62950", "url": "https://www.uniprot.org/uniprot/Q62950" } ], "reference": [ { "type": "PubMed", "id": "9375656", "url": "https://glygen.org/publication/PubMed/9375656" } ] } ], "pathway": [ { "id": "rno:25415", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:25415", "resource": "KEGG Pathway" }, { "id": "R-RNO-399956", "name": "CRMPs in Sema3A signaling", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-399956", "resource": "Reactome", "description": "CRMPs in Sema3A signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "P97427-1", "protein_name": "Dihydropyrimidinase-related protein 1", "gene_name": "Crmp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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