{
    "uniprot_canonical_ac": "Q5UKY4-1",
    "uniprot_ac": "Q5UKY4",
    "uniprot_id": "MO2R3_MOUSE",
    "mass": {
        "chemical_mass": 33625.0,
        "monoisotopic_mass": 33625.0
    },
    "refseq": {
        "ac": "NP_001121604",
        "name": "cell surface glycoprotein CD200 receptor 3 isoform 1 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604"
    },
    "gene_names": [
        {
            "name": "Cd200r3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4",
            "id": "Q5UKY4"
        },
        {
            "name": "4733401I18Rik; 4833409J19Rik; mCD200RLb",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604",
            "id": "NP_001121604"
        },
        {
            "name": "Cd200r3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604",
            "id": "NP_001121604"
        },
        {
            "name": "Cd200rlb",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4",
            "id": "Q5UKY4"
        }
    ],
    "protein_names": [
        {
            "name": "Cell surface glycoprotein CD200 receptor 3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q5UKY4"
        },
        {
            "name": "CD200 cell surface glycoprotein receptor-like 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5UKY4"
        },
        {
            "name": "CD200 cell surface glycoprotein receptor-like b",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5UKY4"
        },
        {
            "name": "CD200 receptor-like 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5UKY4"
        },
        {
            "name": "CD200RLb",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5UKY4"
        },
        {
            "name": "Cell surface glycoprotein OX2 receptor 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5UKY4"
        },
        {
            "name": "cell surface glycoprotein CD200 receptor 3 isoform 1 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604",
            "id": "NP_001121604"
        },
        {
            "name": "cell surface glycoprotein CD200 receptor 3; CD200 cell surface glycoprotein receptor 3; CD200RLb; CD200 receptor-like 3; cell surface glycoprotein OX2 receptor 3; CD200 cell surface glycoprotein receptor-like 3; CD200 cell surface glycoprotein receptor-like b",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604",
            "id": "NP_001121604"
        }
    ],
    "function": [
        {
            "annotation": "According to PubMed:15187158 isoform 4 is a receptor for the CD200 cell surface glycoprotein. According to PubMed:16081818 isoform 4 is not a receptor for the CD200/OX2 cell surface glycoprotein. Isoform 1, isoform 2 and isoform 3 are involved in the recruitment or surface expression of the TYROBP receptor. Isoform 6, isoform 7 and isoform 8 are not involved in the recruitment or surface expression of the TYROBP receptor.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5UKY4",
                    "url": "https://www.uniprot.org/uniprot/Q5UKY4#function"
                },
                {
                    "database": "PubMed",
                    "id": "12960329",
                    "url": "https://glygen.org/publication/PubMed/12960329"
                },
                {
                    "database": "PubMed",
                    "id": "15187158",
                    "url": "https://glygen.org/publication/PubMed/15187158"
                },
                {
                    "database": "PubMed",
                    "id": "16081818",
                    "url": "https://glygen.org/publication/PubMed/16081818"
                },
                {
                    "database": "PubMed",
                    "id": "15471863",
                    "url": "https://glygen.org/publication/PubMed/15471863"
                }
            ]
        },
        {
            "annotation": "CD200R3 functions as an activating receptor on mast cells and basophils to regulate IgE-independent immune responses in cooperation with an inhibitory receptor CD200R",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001121604",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604"
                },
                {
                    "database": "PubMed",
                    "id": "17982101",
                    "url": "https://glygen.org/publication/PubMed/17982101"
                }
            ]
        },
        {
            "annotation": "During parasitic helminth infection, we identified CD200 receptor-like 3 as a transcript highly expressed in basophils and mast cells",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001121604",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604"
                },
                {
                    "database": "PubMed",
                    "id": "15471863",
                    "url": "https://glygen.org/publication/PubMed/15471863"
                }
            ]
        },
        {
            "annotation": "Expression of the immunoregulatory protein CD200 increases as murine dendritic cells undergo apoptosis.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001121604",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604"
                },
                {
                    "database": "PubMed",
                    "id": "14644999",
                    "url": "https://glygen.org/publication/PubMed/14644999"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5UKY4",
                    "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Cd200r3",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4",
            "locus": {
                "chromosome": "16",
                "start_pos": 44801743,
                "end_pos": 44764041,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000036172",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000036172"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000036172",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000036172",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "74603",
            "url": "https://www.ncbi.nlm.nih.gov/gene/74603",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR007110",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR040012",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR040012",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:74603",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74603",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1921853",
            "url": "http://www.informatics.jax.org/marker/MGI:1921853",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "GFRTTIC",
            "url": "https://omabrowser.org/oma/group/GFRTTIC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4837998at2759",
            "url": "http://www.orthodb.org/?query=4837998at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR21462",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21462",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR21462:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21462:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q5UKY4",
            "url": "http://purl.obolibrary.org/obo/PR_Q5UKY4",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001121604",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q7T2",
            "url": "https://www.uniprot.org/uniprot/E9Q7T2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q7T2-1",
            "url": "https://www.uniprot.org/uniprot/E9Q7T2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4-1",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4-2",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4-3",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4-3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4-4",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4-4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4-5",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4-5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4-6",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4-6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4-7",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4-7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4-8",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4-8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5UKY4-9",
            "url": "https://www.uniprot.org/uniprot/Q5UKY4-9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGENRTVVCEAIASKPAMQILWTPDEDCVTKSKSHNDTMIVRSKCHREKNNGHSVFCFISHLTDNWILSMEQNRGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFSSRDLVFMKERRSKRSVWQREALG",
        "length": 296,
        "header": "sp|Q5UKY4-1|MO2R3_MOUSE Isoform 1 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
    },
    "isoforms": [
        {
            "isoform_ac": "E9Q7T2-1",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGENRTVVCEAIASKPAMQILWTPDEDCVTKSKSHNDTMIVRSKCHREKNNGHSVFCFISHLTDNWILSMEQNRGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFR",
                "length": 273,
                "header": "tr|E9Q7T2-1|E9Q7T2_MOUSE Computationally mapped isoform of CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=3 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 44778197,
                "end_pos": 44764136,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000166731.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000166731.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000128974.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000128974.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5UKY4-1",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGENRTVVCEAIASKPAMQILWTPDEDCVTKSKSHNDTMIVRSKCHREKNNGHSVFCFISHLTDNWILSMEQNRGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFSSRDLVFMKERRSKRSVWQREALG",
                "length": 296,
                "header": "sp|Q5UKY4-1|MO2R3_MOUSE Isoform 1 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 44785728,
                "end_pos": 44764136,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000048479",
                        "url": "https://www.ensembl.org/id/ENSMUST00000048479"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000036624",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000036624"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5UKY4-2",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGENRTVVCEAIASKPAMQILWTPDEDCVTKSKSHNDTMIVRSKCHREKNNGHSVFCFISHLTDNWILSMEQNRGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFRSNEEPTTLAPT",
                "length": 284,
                "header": "sp|Q5UKY4-2|MO2R3_MOUSE Isoform 2 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 44785042,
                "end_pos": 44764136,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000114613",
                        "url": "https://www.ensembl.org/id/ENSMUST00000114613"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000110260",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000110260"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5UKY4-3",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGENRTVVCEAIASKPAMQILWTPDEDCVTKSKSHNDTMIVRSKCHREKNNGHSVFCFISHLTDNWILSMEQNRGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFRVPEGS",
                "length": 278,
                "header": "sp|Q5UKY4-3|MO2R3_MOUSE Isoform 3 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 44785960,
                "end_pos": 44764136,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000114611",
                        "url": "https://www.ensembl.org/id/ENSMUST00000114611"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000110258",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000110258"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5UKY4-4",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGENRTVVCEAIASKPAMQILWTPDEDCVTKSKSHNDTMIVRSKCHREKNNGHSVFCFISHLTDNWILSMEQNRGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFRWI",
                "length": 275,
                "header": "sp|Q5UKY4-4|MO2R3_MOUSE Isoform 4 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 44801165,
                "end_pos": 44764136,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000164007",
                        "url": "https://www.ensembl.org/id/ENSMUST00000164007"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000130480",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000130480"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5UKY4-5",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGENRTVVCEAIASKPAMQILWTPDEDCVTKSKSHNDTMIVRSKCHREKNNGHSCVLLYLPFD",
                "length": 226,
                "header": "sp|Q5UKY4-5|MO2R3_MOUSE Isoform 5 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "Q5UKY4-6",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFSSRDLVFMKERRSKRSVWQREALG",
                "length": 223,
                "header": "sp|Q5UKY4-6|MO2R3_MOUSE Isoform 6 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 44785728,
                "end_pos": 44764136,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000077178",
                        "url": "https://www.ensembl.org/id/ENSMUST00000077178"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000076421",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000076421"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5UKY4-7",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFRSNEEPTTLAPT",
                "length": 211,
                "header": "sp|Q5UKY4-7|MO2R3_MOUSE Isoform 7 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 44785042,
                "end_pos": 44764136,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000114612",
                        "url": "https://www.ensembl.org/id/ENSMUST00000114612"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000110259",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000110259"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5UKY4-8",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFRVPEGS",
                "length": 205,
                "header": "sp|Q5UKY4-8|MO2R3_MOUSE Isoform 8 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 44785960,
                "end_pos": 44764136,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000114622",
                        "url": "https://www.ensembl.org/id/ENSMUST00000114622"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000110269",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000110269"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5UKY4-9",
            "url": "",
            "sequence": {
                "sequence": "MHALGRTLALMLLIFITILVPESSCSVKGREEIPPDDSFPFSDDNIFPDGVGVTMEIEIITPVSVQIGIKAQLFCHPSPSKEATLRIWEITPRDWPSCRLPYRAELQQISKKICTERGTTRVPAHHQSSDLPIKSMALKHDGHYSCRIETTDGIFQERHSIQVPGTTSILPSLLSILYVKLAVTVLIVGFAFFQKRNYFRWI",
                "length": 202,
                "header": "sp|Q5UKY4-9|MO2R3_MOUSE Isoform 9 of Cell surface glycoprotein CD200 receptor 3  OS=Mus musculus OX=10090 GN=Cd200r3 PE=1 SV=1 CANONICAL=Q5UKY4-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 44801165,
                "end_pos": 44764136,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000171779",
                        "url": "https://www.ensembl.org/id/ENSMUST00000171779"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000132938",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000132938"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 167,
            "start_aa": "Asn",
            "end_pos": 167,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn167",
            "evidence": [
                {
                    "id": "Q5UKY4",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q5UKY4#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 199,
            "start_aa": "Asn",
            "end_pos": 199,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn199",
            "evidence": [
                {
                    "id": "Q5UKY4",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q5UKY4#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.",
            "journal": "J. Immunol.",
            "date": "2003",
            "authors": "Wright GJ, Cherwinski H, Foster-Cuevas M, Brooke G, Puklavec MJ, Bigler M, Song Y, Jenmalm M, Gorman D, McClanahan T, Liu MR, Brown MH, Sedgwick JD, Phillips JH, Barclay AN",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5UKY4",
                    "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12960329",
                    "url": "https://glygen.org/publication/PubMed/12960329"
                }
            ]
        },
        {
            "title": "CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance.",
            "journal": "Blood",
            "date": "2004",
            "authors": "Rosenblum MD, Olasz E, Woodliff JE, Johnson BD, Konkol MC, Gerber KA, Orentas RJ, Sandford G, Truitt RL",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001121604",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "14644999",
                    "url": "https://glygen.org/publication/PubMed/14644999"
                }
            ]
        },
        {
            "title": "CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules.",
            "journal": "J. Immunol.",
            "date": "2004",
            "authors": "Gorczynski R, Chen Z, Kai Y, Lee L, Wong S, Marsden PA",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5UKY4",
                    "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15187158",
                    "url": "https://glygen.org/publication/PubMed/15187158"
                }
            ]
        },
        {
            "title": "Structural and functional heterogeneity in the CD200R family of immunoregulatory molecules and their expression at the feto-maternal interface.",
            "journal": "Am. J. Reprod. Immunol.",
            "date": "2004",
            "authors": "Gorczynski RM, Chen Z, Clark DA, Kai Y, Lee L, Nachman J, Wong S, Marsden P",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5UKY4",
                    "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15274657",
                    "url": "https://glygen.org/publication/PubMed/15274657"
                }
            ]
        },
        {
            "title": "CD200 receptor family members represent novel DAP12-associated activating receptors on basophils and mast cells.",
            "journal": "J. Biol. Chem.",
            "date": "2004",
            "authors": "Voehringer D, Rosen DB, Lanier LL, Locksley RM",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5UKY4",
                    "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001121604",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15471863",
                    "url": "https://glygen.org/publication/PubMed/15471863"
                }
            ]
        },
        {
            "title": "Recombinant CD200 protein does not bind activating proteins closely related to CD200 receptor.",
            "journal": "J. Immunol.",
            "date": "2005",
            "authors": "Hatherley D, Cherwinski HM, Moshref M, Barclay AN",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5UKY4",
                    "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16081818",
                    "url": "https://glygen.org/publication/PubMed/16081818"
                }
            ]
        },
        {
            "title": "Mast cells and basophils are selectively activated in vitro and in vivo through CD200R3 in an IgE-independent manner.",
            "journal": "Journal of immunology (Baltimore, Md. : 1950)",
            "date": "2007",
            "authors": "Kojima T, Obata K, Mukai K, Sato S, Takai T, Minegishi Y, Karasuyama H",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001121604",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121604"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17982101",
                    "url": "https://glygen.org/publication/PubMed/17982101"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:74603",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74603",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZJX0-1",
            "protein_name": "CD200 receptor 1-like",
            "gene_name": "Cd200r1l",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MHALWKTPALTLLIFITMLVTESSCPDKNQTMQNSSSPMPEVNTTVFVQMGTKALLCCPSSPLTKVVLVTWIITPRGQPPCIISYKAETRETHESNCSDRSITWASTPDLPPDLQISAVALQHEGRYSCDIALPDGNFRNIYDLQVLVPPEAIHFPGENRTAVCEAIAGKPAAQITWTPDGDCVTKTESHSNGTVTVRSTCNWEQSNVSVVFCVVSHLTTGNQSLSIELGRGGTSSPPSLLTIIYVKMALLGIILLIVGFSFFQKRNYTR",
                "length": 270
            },
            "evidence": [
                {
                    "id": "45238363",
                    "url": "http://www.informatics.jax.org/homology/45238363",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q6Q8B3-1",
            "protein_name": "Cell surface glycoprotein CD200 receptor 2",
            "gene_name": "CD200R1L",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSAPRLLISIIIMVSASSSSCMGGKQMTQNYSTIFAEGNISQPVLMDINAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTVERITWVSRPDQNSDLQIRPVDTTHDGYYRGIVVTPDGNFHRGYHLQVLVTPEVNLFQSRNITAVCKAVTGKPAAQISWIPEGSILATKQEYWGNGTVTVKSTCPWEGHKSTVTCHVSHLTGNKSLSVKLNSGLRTSGSPALSLLIILYVKLSLFVVILVTTGFVFFQRINHVRKVL",
                "length": 271
            },
            "evidence": [
                {
                    "id": "45238363",
                    "url": "http://www.informatics.jax.org/homology/45238363",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TD46-4",
            "protein_name": "Cell surface glycoprotein CD200 receptor 1",
            "gene_name": "CD200R1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MLCPWRTANLGLLLILTIFLVAEAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLYIPYIILTIIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVDTDLHTL",
                "length": 348
            },
            "evidence": [
                {
                    "id": "45238363",
                    "url": "http://www.informatics.jax.org/homology/45238363",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
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                                "database": "UniProtKB",
                                "id": "Q5UKY4",
                                "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
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                                "id": "Q5UKY4",
                                "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell surface",
                        "id": "GO:0009986",
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                                "id": "Q5UKY4",
                                "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "external side of plasma membrane",
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                        "evidence": [
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                                "id": "Q5UKY4",
                                "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "signaling receptor activity",
                        "id": "GO:0038023",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023",
                        "evidence": [
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                                "database": "UniProtKB",
                                "id": "Q5UKY4",
                                "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "regulation of neuroinflammatory response",
                        "id": "GO:0150077",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150077",
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                                "id": "Q5UKY4",
                                "url": "https://www.uniprot.org/uniprot/Q5UKY4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
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            "end_pos": 169,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 199,
            "end_pos": 201,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 2
                },
                {
                    "field": "total_sites",
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                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
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                    "field": "o_linked_glycan_sites",
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        {
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}