{
    "uniprot_canonical_ac": "Q5RKJ1-1",
    "uniprot_ac": "Q5RKJ1",
    "uniprot_id": "MAEA_RAT",
    "mass": {
        "chemical_mass": 45336.0,
        "monoisotopic_mass": 45336.0
    },
    "refseq": {
        "ac": "NP_001008320",
        "name": "E3 ubiquitin-protein transferase MAEA",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008320"
    },
    "gene_names": [
        {
            "name": "Maea",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q5RKJ1",
            "id": "Q5RKJ1"
        },
        {
            "name": "Maea",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008320",
            "id": "NP_001008320"
        }
    ],
    "protein_names": [
        {
            "name": "E3 ubiquitin-protein transferase MAEA",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q5RKJ1"
        },
        {
            "name": "2.3.2.27",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5RKJ1"
        },
        {
            "name": "E3 ubiquitin-protein transferase MAEA",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008320",
            "id": "NP_001008320"
        },
        {
            "name": "Macrophage erythroblast attacher",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5RKJ1"
        }
    ],
    "function": [
        {
            "annotation": "Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages (By similarity). Mediates the attachment of erythroid cell to mature macrophages; this MAEA-mediated contact inhibits erythroid cell apoptosis (By similarity). Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages (By similarity). May contribute to nuclear architecture and cells division events (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5RKJ1",
                    "url": "https://www.uniprot.org/uniprot/Q5RKJ1#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q4VC33",
                    "url": "https://www.uniprot.org/uniprot/Q4VC33#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q7L5Y9",
                    "url": "https://www.uniprot.org/uniprot/Q7L5Y9#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5RKJ1",
                    "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Maea",
            "url": "https://www.uniprot.org/uniprot/Q5RKJ1",
            "locus": {
                "chromosome": "14",
                "start_pos": 77357264,
                "end_pos": 77390671,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000005397",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000005397"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000005397",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000005397",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd16659",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16659",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "298982",
            "url": "https://www.ncbi.nlm.nih.gov/gene/298982",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR006594",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006595",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006595",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013144",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013144",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR024964",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR024964",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR044063",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR044063",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR045098",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR045098",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:298982",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:298982",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "CHDNRSK",
            "url": "https://omabrowser.org/oma/group/CHDNRSK/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1429623at2759",
            "url": "http://www.orthodb.org/?query=1429623at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12170",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12170",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12170:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12170:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF10607",
            "url": "http://pfam.xfam.org/family/PF10607",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q5RKJ1",
            "url": "http://purl.obolibrary.org/obo/PR_Q5RKJ1",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001008320",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008320",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1309877",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1309877",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8L2Q2K9",
            "url": "https://www.uniprot.org/uniprot/A0A8L2Q2K9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8L2Q2K9-1",
            "url": "https://www.uniprot.org/uniprot/A0A8L2Q2K9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5RKJ1",
            "url": "https://www.uniprot.org/uniprot/Q5RKJ1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5RKJ1-1",
            "url": "https://www.uniprot.org/uniprot/Q5RKJ1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAVQESAAQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASMWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFPPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM",
        "length": 396,
        "header": "sp|Q5RKJ1-1|MAEA_RAT Isoform 1 of E3 ubiquitin-protein transferase MAEA  OS=Rattus norvegicus OX=10116 GN=Maea PE=2 SV=2 CANONICAL=Q5RKJ1-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8L2Q2K9-1",
            "url": "",
            "sequence": {
                "sequence": "MAVQESAAQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASMWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKVCKLSGLGSWWEHARKHFSQAEGSQLDEVRQVMGMLAFPPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM",
                "length": 382,
                "header": "tr|A0A8L2Q2K9-1|A0A8L2Q2K9_RAT Computationally mapped isoform of RING-type E3 ubiquitin transferase  OS=Rattus norvegicus OX=10116 GN=Maea PE=4 SV=1 CANONICAL=Q5RKJ1-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 77390650,
                "end_pos": 77358191,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000007181.6",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000007181.6"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000007181.5",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000007181.5"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5RKJ1-1",
            "url": "",
            "sequence": {
                "sequence": "MAVQESAAQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASMWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFPPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM",
                "length": 396,
                "header": "sp|Q5RKJ1-1|MAEA_RAT Isoform 1 of E3 ubiquitin-protein transferase MAEA  OS=Rattus norvegicus OX=10116 GN=Maea PE=2 SV=2 CANONICAL=Q5RKJ1-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 28,
            "end_pos": 28,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "Phosphothreonine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5RKJ1",
                    "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                }
            ],
            "site_lbl": "Thr28"
        }
    ],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [],
    "pathway": [
        {
            "id": "rno:298982",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:298982",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q4VC33-1",
            "protein_name": "E3 ubiquitin-protein transferase MAEA",
            "gene_name": "Maea",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MAVQESAAQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASMWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFPPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM",
                "length": 396
            },
            "evidence": [
                {
                    "id": "45235682",
                    "url": "http://www.informatics.jax.org/homology/45235682",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q7L5Y9-1",
            "protein_name": "E3 ubiquitin-protein transferase MAEA",
            "gene_name": "MAEA",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAVQESAAQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM",
                "length": 396
            },
            "evidence": [
                {
                    "id": "45235682",
                    "url": "http://www.informatics.jax.org/homology/45235682",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 9,
                "go_terms": [
                    {
                        "name": "erythrocyte maturation",
                        "id": "GO:0043249",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043249",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell adhesion",
                        "id": "GO:0007155",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell division",
                        "id": "GO:0051301",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoskeleton organization",
                        "id": "GO:0007010",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "proteasome-mediated ubiquitin-dependent protein catabolic process",
                        "id": "GO:0043161",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell cycle",
                        "id": "GO:0007049",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007049",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of myeloid cell apoptotic process",
                        "id": "GO:0033033",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033033",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "erythrocyte development",
                        "id": "GO:0048821",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048821",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "enucleate erythrocyte development",
                        "id": "GO:0048822",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048822",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "actin binding",
                        "id": "GO:0003779",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "metal ion binding",
                        "id": "GO:0046872",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin protein ligase activity",
                        "id": "GO:0061630",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 11,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleoplasm",
                        "id": "GO:0005654",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "spindle",
                        "id": "GO:0005819",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoskeleton",
                        "id": "GO:0005856",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "actin cytoskeleton",
                        "id": "GO:0015629",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nuclear matrix",
                        "id": "GO:0016363",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin ligase complex",
                        "id": "GO:0000151",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "actomyosin contractile ring",
                        "id": "GO:0005826",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005826",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "GID complex",
                        "id": "GO:0034657",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RKJ1",
                                "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 185,
            "end_pos": 187,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 282,
            "end_pos": 284,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "Autoubiquitinated as component of the CTLH E3 ubiquitin-protein ligase complex (in vitro).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5RKJ1",
                    "url": "https://www.uniprot.org/uniprot/Q5RKJ1"
                },
                {
                    "database": "PubMed",
                    "id": "Q7L5Y9",
                    "url": "https://glygen.org/publication/PubMed/Q7L5Y9"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                }
            ],
            "sort_fields": [
                "start_pos",
                "end_pos",
                "kinase_uniprot_canonical_ac",
                "kinase_gene_name",
                "residue",
                "comment",
                "site_lbl"
            ]
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}
