{
    "uniprot_canonical_ac": "Q5RJY2-1",
    "uniprot_ac": "Q5RJY2",
    "uniprot_id": "G2E3_MOUSE",
    "mass": {
        "chemical_mass": 81784.0,
        "monoisotopic_mass": 81784.0
    },
    "refseq": {
        "ac": "NP_001015099",
        "name": "G2/M phase-specific E3 ubiquitin-protein ligase isoform 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001015099"
    },
    "gene_names": [
        {
            "name": "G2e3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q5RJY2",
            "id": "Q5RJY2"
        },
        {
            "name": "6030408C04Rik; 9030416F18; D930034K21Rik; mKIAA1333",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161436",
            "id": "NP_001161436"
        },
        {
            "name": "G2e3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161436",
            "id": "NP_001161436"
        },
        {
            "name": "Kiaa1333",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q5RJY2",
            "id": "Q5RJY2"
        }
    ],
    "protein_names": [
        {
            "name": "G2/M phase-specific E3 ubiquitin-protein ligase",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q5RJY2"
        },
        {
            "name": "2.3.2.26",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5RJY2"
        },
        {
            "name": "G2/M phase-specific E3 ubiquitin-protein ligase isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001015099",
            "id": "NP_001015099"
        },
        {
            "name": "G2/M phase-specific E3 ubiquitin-protein ligase isoform 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161435",
            "id": "NP_001161435"
        },
        {
            "name": "G2/M phase-specific E3 ubiquitin-protein ligase isoform 3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161436",
            "id": "NP_001161436"
        },
        {
            "name": "G2/M phase-specific E3 ubiquitin-protein ligase; G2/M phase-specific HECT-type E3 ubiquitin transferase",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001015099",
            "id": "NP_001015099"
        },
        {
            "name": "G2/M phase-specific HECT-type E3 ubiquitin transferase",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5RJY2"
        }
    ],
    "function": [
        {
            "annotation": "E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity). Required for prevention of apoptotic death in early embryogenesis.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5RJY2",
                    "url": "https://www.uniprot.org/uniprot/Q5RJY2#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q7L622",
                    "url": "https://www.uniprot.org/uniprot/Q7L622#function"
                },
                {
                    "database": "PubMed",
                    "id": "18511420",
                    "url": "https://glygen.org/publication/PubMed/18511420"
                }
            ]
        },
        {
            "annotation": "G2E3 is a dual function ubiquitin ligase essential for prevention of apoptosis in early embryogenesis",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161435",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161435"
                },
                {
                    "database": "PubMed",
                    "id": "18511420",
                    "url": "https://glygen.org/publication/PubMed/18511420"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001161436",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161436"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001015099",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001015099"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5RJY2",
                    "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "G2e3",
            "url": "https://www.uniprot.org/uniprot/Q5RJY2",
            "locus": {
                "chromosome": "12",
                "start_pos": 51423769,
                "end_pos": 51394844,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000035293",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000035293"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000035293",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000035293",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd15496",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15496",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd15669",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15669",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "217558",
            "url": "https://www.ncbi.nlm.nih.gov/gene/217558",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q5RJY2",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q5RJY2*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR000569",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001965",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011011",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013083",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR019786",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR034732",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR035983",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR042012",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR042012",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR042013",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR042013",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:217558",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:217558",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "2444298",
            "url": "http://www.informatics.jax.org/marker/MGI:2444298",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "MEFTIRN",
            "url": "https://omabrowser.org/oma/group/MEFTIRN/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2899995at2759",
            "url": "http://www.orthodb.org/?query=2899995at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12420",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12420",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12420:SF37",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12420:SF37",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00632",
            "url": "http://pfam.xfam.org/family/PF00632",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13771",
            "url": "http://pfam.xfam.org/family/PF13771",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q5RJY2",
            "url": "http://purl.obolibrary.org/obo/PR_Q5RJY2",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001015099",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001015099",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q7C2",
            "url": "https://www.uniprot.org/uniprot/E9Q7C2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q7C2-1",
            "url": "https://www.uniprot.org/uniprot/E9Q7C2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q7E5",
            "url": "https://www.uniprot.org/uniprot/E9Q7E5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q7E5-1",
            "url": "https://www.uniprot.org/uniprot/E9Q7E5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5RJY2",
            "url": "https://www.uniprot.org/uniprot/Q5RJY2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5RJY2-1",
            "url": "https://www.uniprot.org/uniprot/Q5RJY2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MNENKPDNSQSLACVFCRKNDDCPNKYGEKKTYEKWNFSVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVQRASKLKCTVCKKNGASIGCVVPTCKRSYHLPCGLQKECIFQFTDNFASFCWKHRPVQAITSNKYSSSLPCTICLEFVEPIPTYNILQSPCCKNAWFHRDCLQVQAINAGVFFFRCTLCNNTDIFQKEMLRMGIHIPEKDASWELEENAYQELLQSHDRCDIRRCHCKKGRDYNEPNSKWEVKRCQSCGSSGTHLACSSLQSWEQNWECLDCRRITYTSDFQKAPKHPLANSTNVTVTDCLLEESSSKLPRQSTVAQHKELLRQGSKFRRDISTILIELGFQIKKKTKTLYINKANVWRSALEQFQSQKFNPSCSIDVVYVNGNEVGSQHLGSKQEFLSHLMHHLENSSVFEGSLAKNLSLNSQAVKENLYYEVGKMLAISLVHGGPSPGFFSETLFNCLAYGPENTLPTLDDVSDIDVAQIIIKIDSATDLNILNSVISQHYNYLEVSGCLRLTTSLSDKFMLVKDILFYHVINRVKAPFESFKQGLKTLGVLEKIQTYPEAFYKILCHKPENLSAKNLSDLFTIHSVADVQTLRFWNSYLKAIEDGKSATTMEDILIFATGCSSVPPTGFKPSLSVECLHVDFPVADKYRNHLVLPATNTYEEFQENMDFTIRDTLRLEKEERSHILPRTLNVSSNEEMLI",
        "length": 716,
        "header": "sp|Q5RJY2-1|G2E3_MOUSE Isoform 1 of G2/M phase-specific E3 ubiquitin-protein ligase  OS=Mus musculus OX=10090 GN=G2e3 PE=2 SV=2 CANONICAL=Q5RJY2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "E9Q7C2-1",
            "url": "",
            "sequence": {
                "sequence": "MNENKPDNSQSLACVFCRKNDDCPNKYGEKKTYEKWNFSVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVQRASKLKCTVCKKNGASIGCVVPTCKRSYHLPCGLQKECIFQFTDNFASFCWKHRPVQAITSNKYSSSLPCTICLEFVEPIPTYNILQSPCCKNAWFHRDCLQVQAINAGVFFFRCTLCNNTDIFQKEMLRMGIHIPEKDASWELEENAYQELLQSHDRCDIRRCHCKKGRDYNEPNSKWEVKRCQSCGSSGTHLACSSLQSWEQNWECLDCRRITYTSDFQKAPKHPLANSTNVTVTDCLLEESSSKLPRQSTVAQHKELLRLKQEIQLSTTACIFRRQSCLTQRQGSKFRRDISTILIELGFQIKKKTKTLYINKANVWRSALEQFQSQKFNPSCSIDVVYVNGNEVGSQHLGSKQEFLSHLMHHLENSSVFEGSLAKNLSLNSQAVKENLYYEVGKMLAISLVHGGPSPGFFSETLFNCLAYGPENTLPTLDDVSDIDVAQIIIKIDSATDLNILNSVISQHYNYLEVSGCLRLTTSLSDKFMLVKDILFYHVINRVKAPFESFKQGLKTLGVLEKIQTYPEAFYKILCHKPENLSAKNLSDLFTIHSVADVQTLRFWNSYLKAIEDGKSATTMEDILIFATGCSSVPPTGFKPSLSVECLHVDFPVADKYRNHLVLPATNTYEEFQENMDFTIRDTLRLEKEERSHILPRTLNVSSNEEMLI",
                "length": 739,
                "header": "tr|E9Q7C2-1|G2E3_MOUSE Computationally mapped isoform of G2/M phase-specific E3 ubiquitin-protein ligase  OS=Mus musculus OX=10090 GN=G2e3 PE=2 SV=1 CANONICAL=Q5RJY2-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 51419502,
                "end_pos": 51398192,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000119211.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000119211.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000113270.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000113270.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "E9Q7E5-1",
            "url": "",
            "sequence": {
                "sequence": "MNENKPDNSQSLACVFCRKNDDCPNKYGEKKTYEKWNFSVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVQRASKLKCTVCKKNGASIGCVVPTCKRSYHLPCGLQKECIFQFTDNFASFCWKHRPVQAITSNKYSSSLPCTICLEFVEPIPTYNILQSPCCKNAWFHRDCLQVQAINAGVFFFRCTLCNNTDIFQKEMLRMGIHIPEKDASWELEENAYQELLQSHDRCDIRRCHCKKGRDYNEPNSKWEVKRCQSCGSSGTHLACSSLQSWEQNWECLDCRRITYTSDFQKAPKHPLANSTNVTVTDCLLEESSSKLPRQSTVAQHKELLSLFLSVFTAVKENLYYEVGKMLAISLVHGGPSPGFFSETLFNCLAYGPENTLPTLDDVSDIDVAQIIIKIDSATDLNILNSVISQHYNYLEVSGCLRLTTSLSDKFMLVKDILFYHVINRVKAPFESFKQGLKTLGVLEKIQTYPEAFYKILCHKPENLSAKNLSDLFTIHSVADVQTLRFWNSYLKAIEDGKSATTMEDILIFATGCSSVPPTGFKPSLSVECLHVDFPVADKYRNHLVLPATNTYEEFQENMDFTIRDTLRLEKEERSHILPRTLNVSSNEEMLI",
                "length": 622,
                "header": "tr|E9Q7E5-1|G2E3_MOUSE Computationally mapped isoform of G2/M phase-specific E3 ubiquitin-protein ligase  OS=Mus musculus OX=10090 GN=G2e3 PE=2 SV=1 CANONICAL=Q5RJY2-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 51419502,
                "end_pos": 51398192,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000121521.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000121521.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000113191.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000113191.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5RJY2-1",
            "url": "",
            "sequence": {
                "sequence": "MNENKPDNSQSLACVFCRKNDDCPNKYGEKKTYEKWNFSVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVQRASKLKCTVCKKNGASIGCVVPTCKRSYHLPCGLQKECIFQFTDNFASFCWKHRPVQAITSNKYSSSLPCTICLEFVEPIPTYNILQSPCCKNAWFHRDCLQVQAINAGVFFFRCTLCNNTDIFQKEMLRMGIHIPEKDASWELEENAYQELLQSHDRCDIRRCHCKKGRDYNEPNSKWEVKRCQSCGSSGTHLACSSLQSWEQNWECLDCRRITYTSDFQKAPKHPLANSTNVTVTDCLLEESSSKLPRQSTVAQHKELLRQGSKFRRDISTILIELGFQIKKKTKTLYINKANVWRSALEQFQSQKFNPSCSIDVVYVNGNEVGSQHLGSKQEFLSHLMHHLENSSVFEGSLAKNLSLNSQAVKENLYYEVGKMLAISLVHGGPSPGFFSETLFNCLAYGPENTLPTLDDVSDIDVAQIIIKIDSATDLNILNSVISQHYNYLEVSGCLRLTTSLSDKFMLVKDILFYHVINRVKAPFESFKQGLKTLGVLEKIQTYPEAFYKILCHKPENLSAKNLSDLFTIHSVADVQTLRFWNSYLKAIEDGKSATTMEDILIFATGCSSVPPTGFKPSLSVECLHVDFPVADKYRNHLVLPATNTYEEFQENMDFTIRDTLRLEKEERSHILPRTLNVSSNEEMLI",
                "length": 716,
                "header": "sp|Q5RJY2-1|G2E3_MOUSE Isoform 1 of G2/M phase-specific E3 ubiquitin-protein ligase  OS=Mus musculus OX=10090 GN=G2e3 PE=2 SV=2 CANONICAL=Q5RJY2-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 51419502,
                "end_pos": 51398192,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000054308",
                        "url": "https://www.ensembl.org/id/ENSMUST00000054308"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000054474",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000054474"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [
        {
            "title": "G2E3 is a dual function ubiquitin ligase required for early embryonic development.",
            "journal": "J. Biol. Chem.",
            "date": "2008",
            "authors": "Brooks WS, Helton ES, Banerjee S, Venable M, Johnson L, Schoeb TR, Kesterson RA, Crawford DF",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5RJY2",
                    "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001161435",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161435"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001161436",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161436"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001015099",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001015099"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18511420",
                    "url": "https://glygen.org/publication/PubMed/18511420"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:217558",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:217558",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZC11-1",
            "protein_name": "G2/M-phase specific E3 ubiquitin protein ligase",
            "gene_name": "G2e3",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MNENKPGNSQSLACVFCRKNDDCPNKYGEKKTCEKWNFSVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCTVCKKNGASIGCVVPQCKRSYHLPCGLQKECIFQFTDNFASFCWKHRPVQAITSNKYRDSLPCTICLEFVEPIPTYNILQSPCCKNAWFHRDCLQVQAINAGVFFFRCTLCNNTDIFQKEMLRMGIHIPEKDASWELEENAYQELLQSHDRCDVRRCHCKEGREYNEPNSKWEIKRCQCCGSSGTHLACSSLQSWEKNWECLDCRRIAYTSDFQKAPKHPLANSTNVTVTDCLLEESSPKLPRQSTVAQQKELLRQGSKFRRDISTILIELGFQIKKKAKTLYINKANVWRSAVEQFQSQKFNPSYSIEVVYVNDNDEVGSKHPGSKQEFLSHLMHHLENSSVFEGSLAKNLSLNSQAVKENLYYEAGKMLAISLVHGGPSPGFFSETLFKCLAYGPENALPTLDDVSDLDVAQIIIKIDTAADLNILKSVINEYYNYLEFSGCLRLMTTLSDKYMLVKDILFYQVIKRVKAPFESFKQGLKTLGVLEKIQAYPEAFYNILCHKPESLSAKNLSDLFTIHKLPDVKTSRFWNSYLQAVEDGKSATTLEDILHFATGCSSVPPTGFKPAPSIECLHGDFPVANKCNNCLALPVTNTYEEFQENMDFAIRDSIRLEKEERSHLLPRTLNVSSNEEMLF",
                "length": 717
            },
            "evidence": [
                {
                    "id": "45226002",
                    "url": "http://www.informatics.jax.org/homology/45226002",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q7L622-1",
            "protein_name": "G2/M phase-specific E3 ubiquitin-protein ligase",
            "gene_name": "G2E3",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKKHVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKKTKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHLENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPENTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLVKDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFTVHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDFPVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH",
                "length": 706
            },
            "evidence": [
                {
                    "id": "45226002",
                    "url": "http://www.informatics.jax.org/homology/45226002",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "metal ion binding",
                        "id": "GO:0046872",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin-protein transferase activity",
                        "id": "GO:0004842",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin protein ligase activity",
                        "id": "GO:0061630",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "Golgi apparatus",
                        "id": "GO:0005794",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleolus",
                        "id": "GO:0005730",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "intracellular membrane-bounded organelle",
                        "id": "GO:0043231",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 4,
                "go_terms": [
                    {
                        "name": "apoptotic process",
                        "id": "GO:0006915",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein polyubiquitination",
                        "id": "GO:0000209",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of intrinsic apoptotic signaling pathway",
                        "id": "GO:2001243",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001243",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "blastocyst development",
                        "id": "GO:0001824",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001824",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5RJY2",
                                "url": "https://www.uniprot.org/uniprot/Q5RJY2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 193,
            "end_pos": 195,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 304,
            "end_pos": 306,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 307,
            "end_pos": 309,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 37,
            "end_pos": 39,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 420,
            "end_pos": 422,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 431,
            "end_pos": 433,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 587,
            "end_pos": 589,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 592,
            "end_pos": 594,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 707,
            "end_pos": 709,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                {
                    "field": "n_linked_glycans",
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                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
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                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
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                {
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                {
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
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            ],
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        {
            "table_id": "glycosylation_predicted",
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                    "field": "total",
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                {
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                {
                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": []
        },
        {
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        {
            "table_id": "phosphorylation",
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                {
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            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
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            ],
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        {
            "table_id": "snv_disease",
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        {
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        }
    ]
}