{
    "uniprot_canonical_ac": "Q5PPN4-1",
    "uniprot_ac": "Q5PPN4",
    "uniprot_id": "CAH8_RAT",
    "mass": {
        "chemical_mass": 32962.0,
        "monoisotopic_mass": 32962.0
    },
    "refseq": {
        "ac": "NP_001009662",
        "name": "carbonic anhydrase-related protein",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009662"
    },
    "gene_names": [
        {
            "name": "Ca8",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q5PPN4",
            "id": "Q5PPN4"
        },
        {
            "name": "Car8",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q5PPN4",
            "id": "Q5PPN4"
        },
        {
            "name": "Ca8",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009662",
            "id": "NP_001009662"
        },
        {
            "name": "Car8",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009662",
            "id": "NP_001009662"
        },
        {
            "name": "Car8",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q5PPN4",
            "id": "Q5PPN4"
        }
    ],
    "protein_names": [
        {
            "name": "Carbonic anhydrase-related protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q5PPN4"
        },
        {
            "name": "CA-VIII",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5PPN4"
        },
        {
            "name": "CARP; CA-VIII; carbonic anhydrase VIII",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009662",
            "id": "NP_001009662"
        },
        {
            "name": "CARP",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5PPN4"
        },
        {
            "name": "Carbonic anhydrase VIII",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5PPN4"
        },
        {
            "name": "carbonic anhydrase-related protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009662",
            "id": "NP_001009662"
        }
    ],
    "function": [
        {
            "annotation": "Does not have a carbonic anhydrase catalytic activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5PPN4",
                    "url": "https://www.uniprot.org/uniprot/Q5PPN4#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050997",
            "recommended_name": {
                "id": "DOID:0050997",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050997",
                "name": "cerebellar ataxia, mental retardation and dysequlibrium syndrome",
                "description": "An syndrome characterized by congenital onset of nonprogressive cerebellar ataxia, disturbed equilibrium, and mental retardation, associated with cerebellar hypoplasia."
            },
            "synonyms": [
                {
                    "id": "DOID:0050997",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050997",
                    "name": "CAMRQ",
                    "description": ""
                },
                {
                    "id": "DOID:0050997",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050997",
                    "name": "Cerebellar Ataxia, Mental Retardation, and Dysequilibrium Syndrome 1 (CAMRQ1)",
                    "description": ""
                },
                {
                    "id": "DOID:0050997",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050997",
                    "name": "VLDLR Cerebellar Hypoplasia",
                    "description": ""
                },
                {
                    "id": "DOID:0050997",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050997",
                    "name": "Uner Tan syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 4",
                    "description": "Any dysequilibrium syndrome in which the cause of the disease is a mutation in the ATP8A2 gene."
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "ATP8A2 dysequilibrium syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "cerebellar ataxia, mental retardation, and dysequilibrium syndrome 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "cerebellar ataxia, mental retardation, and dysequilibrium syndrome type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "dysequilibrium syndrome caused by mutation in ATP8A2",
                    "description": ""
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "CAMRQ4",
                    "description": ""
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "cerebellar ataxia and intellectual disability with or without quadrupedal locomotion 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0014104",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014104",
                    "name": "cerebellar ataxia and mental retardation with or without quadrupedal locomotion 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 1",
                    "description": "Any dysequilibrium syndrome in which the cause of the disease is a mutation in the VLDLR gene."
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "VLDLR dysequilibrium syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar ataxia, mental retardation, and dysequilibrium syndrome type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar hypoplasia and mental retardation with or without quadrupedal locomotion 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "dysequilibrium syndrome caused by mutation in VLDLR",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "CAMRQ1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar ataxia and intellectual disability with or without quadrupedal locomotion 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar ataxia and mental retardation with or without quadrupedal locomotion 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar ataxia, congenital, and intellectual disability, autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar ataxia, congenital, and mental retardation, autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar ataxia, mental retardation, and dysequilibrium syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "cerebellar hypoplasia, VLDLR-associated",
                    "description": ""
                },
                {
                    "id": "MONDO:0024542",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024542",
                    "name": "dysequilibrium syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 3",
                    "description": "Any dysequilibrium syndrome in which the cause of the disease is a mutation in the CA8 gene."
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "CA8 dysequilibrium syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "cerebellar ataxia, mental retardation, and dysequilibrium syndrome type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "dysequilibrium syndrome caused by mutation in CA8",
                    "description": ""
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "CAMRQ3",
                    "description": ""
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "cerebellar ataxia and intellectual disability with or without quadrupedal locomotion 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0013188",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013188",
                    "name": "cerebellar ataxia and mental retardation with or without quadrupedal locomotion 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 2",
                    "description": "Any dysequilibrium syndrome in which the cause of the disease is a mutation in the WDR81 gene."
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "WDR81 dysequilibrium syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "cerebellar ataxia, intellectual disability, and dysequilibrium syndrome type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "cerebellar ataxia, mental retardation, and dysequilibrium syndrome 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "cerebellar ataxia, mental retardation, and dysequilibrium syndrome type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "dysequilibrium syndrome caused by mutation in WDR81",
                    "description": ""
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "CAMRQ2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "cerebellar ataxia and intellectual disability with or without quadrupedal locomotion 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012430",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012430",
                    "name": "cerebellar ataxia and mental retardation with or without quadrupedal locomotion 2",
                    "description": ""
                },
                {
                    "id": "MIM:615268",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/615268",
                    "name": "Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 4",
                    "description": "Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 4"
                },
                {
                    "id": "MIM:224050",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/224050",
                    "name": "Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1",
                    "description": "Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1"
                },
                {
                    "id": "MIM:613227",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/613227",
                    "name": "Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 3",
                    "description": "Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 3"
                },
                {
                    "id": "MIM:610185",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/610185",
                    "name": "Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 2",
                    "description": "Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 2"
                }
            ],
            "evidence": [
                {
                    "id": "0050997",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050997"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5PPN4",
                    "url": "https://www.uniprot.org/uniprot/Q5PPN4"
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            ],
            "common_name": "Rat"
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        {
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            "locus": {}
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    ],
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        {
            "id": "ENSRNOG00000005669",
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            "categories": [
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        },
        {
            "id": "297814",
            "url": "https://www.ncbi.nlm.nih.gov/gene/297814",
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        },
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            "id": "IPR001148",
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        },
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            "id": "IPR018338",
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        },
        {
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            "categories": [
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        },
        {
            "id": "IPR036398",
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            "categories": [
                "Protein Classification"
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        },
        {
            "id": "IPR041877",
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            "categories": [
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        },
        {
            "id": "rno:297814",
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        },
        {
            "id": "SANGEYQ",
            "url": "https://omabrowser.org/oma/group/SANGEYQ/",
            "database": "OMA",
            "categories": [
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        },
        {
            "id": "49814at2759",
            "url": "http://www.orthodb.org/?query=49814at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
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        },
        {
            "id": "PTHR18952",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
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        },
        {
            "id": "PTHR18952:SF104",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952:SF104",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
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        },
        {
            "id": "PF00194",
            "url": "http://pfam.xfam.org/family/PF00194",
            "database": "Pfam",
            "categories": [
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            ]
        },
        {
            "id": "PR_Q5PPN4",
            "url": "http://purl.obolibrary.org/obo/PR_Q5PPN4",
            "database": "PRO",
            "categories": [
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            ]
        },
        {
            "id": "NP_001009662",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009662",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1304709",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1304709",
            "database": "RGD",
            "categories": [
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            ]
        },
        {
            "id": "A0A0G2K7B9",
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        },
        {
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            "database": "UniProtKB",
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        },
        {
            "id": "A0A8I5Y6A0",
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            "database": "UniProtKB",
            "categories": [
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        },
        {
            "id": "A0A8I5Y6A0-1",
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            "database": "UniProtKB",
            "categories": [
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        },
        {
            "id": "Q5PPN4",
            "url": "https://www.uniprot.org/uniprot/Q5PPN4",
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            "categories": [
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            ]
        },
        {
            "id": "Q5PPN4-1",
            "url": "https://www.uniprot.org/uniprot/Q5PPN4-1",
            "database": "UniProtKB",
            "categories": [
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            ]
        }
    ],
    "sequence": {
        "sequence": "MADLSFIEDAVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGQEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIVIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ",
        "length": 290,
        "header": "sp|Q5PPN4-1|CAH8_RAT Isoform 1 of Carbonic anhydrase-related protein  OS=Rattus norvegicus OX=10116 GN=Ca8 PE=1 SV=3 CANONICAL=Q5PPN4-1"
    },
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        {
            "isoform_ac": "A0A0G2K7B9-1",
            "url": "",
            "sequence": {
                "sequence": "RQLKGNATTCLQTGDSRRHTGVLGLGRLLHLIHWNSTLFGSIDEAVGKPHGIVIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ",
                "length": 179,
                "header": "tr|A0A0G2K7B9-1|A0A0G2K7B9_RAT Computationally mapped isoform of Carbonic anhydrase 8  OS=Rattus norvegicus OX=10116 GN=Car8 PE=1 SV=2 CANONICAL=Q5PPN4-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 21360666,
                "end_pos": 21334158,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000081296.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000081296.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000074141.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000074141.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5Y6A0-1",
            "url": "",
            "sequence": {
                "sequence": "METTLPAPHSPISSLWNFEKLHLIHWNSTLFGSIDEAVGKPHGIVIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ",
                "length": 171,
                "header": "tr|A0A8I5Y6A0-1|A0A8I5Y6A0_RAT Computationally mapped isoform of Carbonic anhydrase 8  OS=Rattus norvegicus OX=10116 GN=Car8 PE=1 SV=1 CANONICAL=Q5PPN4-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 21357959,
                "end_pos": 21334158,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000106574.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000106574.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000077757.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000077757.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5PPN4-1",
            "url": "",
            "sequence": {
                "sequence": "MADLSFIEDAVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGQEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIVIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ",
                "length": 290,
                "header": "sp|Q5PPN4-1|CAH8_RAT Isoform 1 of Carbonic anhydrase-related protein  OS=Rattus norvegicus OX=10116 GN=Ca8 PE=1 SV=3 CANONICAL=Q5PPN4-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 21402295,
                "end_pos": 21334158,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000007802",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000007802"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000007802",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000007802"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 5,
            "end_pos": 5,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5PPN4",
                    "url": "https://www.uniprot.org/uniprot/Q5PPN4"
                },
                {
                    "database": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q5PPN4",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5PPN4"
                }
            ],
            "site_lbl": "Ser5"
        }
    ],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.",
            "journal": "Nature communications",
            "date": "2012",
            "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5PPN4",
                    "url": "https://www.uniprot.org/uniprot/Q5PPN4"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K7B9",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K7B9"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q5PPN4",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5PPN4"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:297814",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:297814",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P28651-1",
            "protein_name": "Carbonic anhydrase-related protein",
            "gene_name": "Ca8",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MADLSFIEDAVAFPEKEEDEEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGQEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQMQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ",
                "length": 291
            },
            "evidence": [
                {
                    "id": "45233573",
                    "url": "http://www.informatics.jax.org/homology/45233573",
                    "database": "MGI"
                },
                {
                    "id": "Q5PPN4",
                    "url": "https://omabrowser.org/oma/group/Q5PPN4/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P35219-1",
            "protein_name": "Carbonic anhydrase-related protein",
            "gene_name": "CA8",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MADLSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ",
                "length": 290
            },
            "evidence": [
                {
                    "id": "45233573",
                    "url": "http://www.informatics.jax.org/homology/45233573",
                    "database": "MGI"
                },
                {
                    "id": "Q5PPN4",
                    "url": "https://omabrowser.org/oma/group/Q5PPN4/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "zinc ion binding",
                        "id": "GO:0008270",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270",
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                            {
                                "database": "UniProtKB",
                                "id": "Q5PPN4",
                                "url": "https://www.uniprot.org/uniprot/Q5PPN4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "carbonate dehydratase activity",
                        "id": "GO:0004089",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089",
                        "evidence": [
                            {
                                "database": "UniProtKB",
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                                "url": "https://www.uniprot.org/uniprot/Q5PPN4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "hydro-lyase activity",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016836",
                        "evidence": [
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                                "id": "Q5PPN4",
                                "url": "https://www.uniprot.org/uniprot/Q5PPN4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
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                                "database": "UniProtKB",
                                "id": "Q5PPN4",
                                "url": "https://www.uniprot.org/uniprot/Q5PPN4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "one-carbon metabolic process",
                        "id": "GO:0006730",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730",
                        "evidence": [
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                                "id": "Q5PPN4",
                                "url": "https://www.uniprot.org/uniprot/Q5PPN4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "phosphatidylinositol-mediated signaling",
                        "id": "GO:0048015",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPN4",
                                "url": "https://www.uniprot.org/uniprot/Q5PPN4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
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    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 146,
            "end_pos": 148,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
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            "table_stats": [
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                    "field": "total",
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                {
                    "field": "total_sites",
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                    "field": "n_linked_glycan_sites",
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                {
                    "field": "o_linked_glycans",
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                    "field": "o_linked_glycan_sites",
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        {
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        {
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        {
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        {
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}