{
    "uniprot_canonical_ac": "Q5PPJ9-1",
    "uniprot_ac": "Q5PPJ9",
    "uniprot_id": "SHLB2_RAT",
    "mass": {
        "chemical_mass": 44853.0,
        "monoisotopic_mass": 44853.0
    },
    "refseq": {
        "ac": "XP_006233878",
        "name": "endophilin-B2 isoform X1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006233878"
    },
    "gene_names": [
        {
            "name": "Sh3glb2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q5PPJ9",
            "id": "Q5PPJ9"
        },
        {
            "name": "Sh3glb2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008759884",
            "id": "XP_008759884"
        }
    ],
    "protein_names": [
        {
            "name": "Endophilin-B2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q5PPJ9"
        },
        {
            "name": "SH3 domain-containing GRB2-like protein B2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q5PPJ9"
        },
        {
            "name": "endophilin-B2 isoform X10",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008759884",
            "id": "XP_008759884"
        },
        {
            "name": "endophilin-B2 isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006233878",
            "id": "XP_006233878"
        },
        {
            "name": "endophilin-B2 isoform X2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008759883",
            "id": "XP_008759883"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5PPJ9",
                    "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Sh3glb2",
            "url": "https://www.uniprot.org/uniprot/Q5PPJ9",
            "locus": {
                "chromosome": "3",
                "start_pos": 13616938,
                "end_pos": 13631757,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000017295",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000017295"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000017295",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000017295",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd07617",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07617",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd11944",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11944",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "311848",
            "url": "https://www.ncbi.nlm.nih.gov/gene/311848",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q5PPJ9",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q5PPJ9*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR001452",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR004148",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR027267",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR035640",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035640",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036028",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:311848",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:311848",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "Q5PPJ9",
            "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5PPJ9",
            "database": "O-GlcNAc Database",
            "categories": [
                "Glycoproteomics"
            ]
        },
        {
            "id": "QMSFYAQ",
            "url": "https://omabrowser.org/oma/group/QMSFYAQ/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3494067at2759",
            "url": "http://www.orthodb.org/?query=3494067at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR14167",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR14167:SF68",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167:SF68",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF03114",
            "url": "http://pfam.xfam.org/family/PF03114",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF14604",
            "url": "http://pfam.xfam.org/family/PF14604",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q5PPJ9",
            "url": "http://purl.obolibrary.org/obo/PR_Q5PPJ9",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-RNO-264870",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-264870",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-6794361",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6794361",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-6798695",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6798695",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001009692",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009692",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1305886",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305886",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2K9P4",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K9P4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K9P4-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K9P4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5Y0M5",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y0M5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5Y0M5-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y0M5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZMU1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZMU1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZMU1-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZMU1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZYB8",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZYB8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZYB8-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZYB8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZZ43",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZZ43",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZZ43-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZZ43-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6GHN4",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GHN4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6GHN4-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GHN4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6GM93",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GM93",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6GM93-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GM93-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A7V1",
            "url": "https://www.uniprot.org/uniprot/D4A7V1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A7V1-1",
            "url": "https://www.uniprot.org/uniprot/D4A7V1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5PPJ9",
            "url": "https://www.uniprot.org/uniprot/Q5PPJ9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q5PPJ9-1",
            "url": "https://www.uniprot.org/uniprot/Q5PPJ9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
        "length": 404,
        "header": "sp|Q5PPJ9-1|SHLB2_RAT Isoform 1 of Endophilin-B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=2 CANONICAL=Q5PPJ9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K9P4-1",
            "url": "",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASAAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 392,
                "header": "tr|A0A0G2K9P4-1|SHLB2_RAT Computationally mapped isoform of Endophilin-B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=2 CANONICAL=Q5PPJ9-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 13631684,
                "end_pos": 13617447,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000085042.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000085042.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000075076.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000075076.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5Y0M5-1",
            "url": "",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASASAVSNPSIMPCPTLASLAHSSCHWLCQLRPGRQQLWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 431,
                "header": "tr|A0A8I5Y0M5-1|SHLB2_RAT Computationally mapped isoform of Endophilin-B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=1 CANONICAL=Q5PPJ9-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 13631684,
                "end_pos": 13617447,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000103772.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000103772.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000077030.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000077030.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5ZMU1-1",
            "url": "",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDLWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 383,
                "header": "tr|A0A8I5ZMU1-1|SHLB2_RAT Computationally mapped isoform of Endophilin-B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=1 CANONICAL=Q5PPJ9-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 13631684,
                "end_pos": 13617447,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000116005.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000116005.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000079486.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000079486.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5ZYB8-1",
            "url": "",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASASATLDDTSRSPPWAEWKEKHPGGWRLPCFFLLPLTPSVTLARGCLSLPEDRKLWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 454,
                "header": "tr|A0A8I5ZYB8-1|A0A8I5ZYB8_RAT Computationally mapped isoform of SH3 domain-containing GRB2-like endophilin B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=1 CANONICAL=Q5PPJ9-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 13631684,
                "end_pos": 13617447,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000100859.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000100859.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000085000.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000085000.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5ZZ43-1",
            "url": "",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASATLDDTSRSPPWAEWKEKHPGGWRLPCFFLLPLTPSVTLARGCLSLPEDRKLWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 450,
                "header": "tr|A0A8I5ZZ43-1|SHLB2_RAT Computationally mapped isoform of Endophilin-B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=1 CANONICAL=Q5PPJ9-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 13631684,
                "end_pos": 13617447,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000116758.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000116758.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000084372.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000084372.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6GHN4-1",
            "url": "",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATLWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 374,
                "header": "tr|A0A8I6GHN4-1|SHLB2_RAT Computationally mapped isoform of Endophilin-B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=1 CANONICAL=Q5PPJ9-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 13631684,
                "end_pos": 13617447,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000107109.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000107109.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000089795.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000089795.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6GM93-1",
            "url": "",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTLDDTSRSPPWAEWKEKHPGGWRLPCFFLLPLTPSVTLARGCLSLPEDRKLWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 429,
                "header": "tr|A0A8I6GM93-1|SHLB2_RAT Computationally mapped isoform of Endophilin-B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=1 CANONICAL=Q5PPJ9-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 13631684,
                "end_pos": 13617447,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000109601.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000109601.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000097875.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000097875.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D4A7V1-1",
            "url": "",
            "sequence": {
                "sequence": "MGSCWLSTWQRQPANWAPTLPMSGLCSAPPHPMTLFPGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISRWLLQTERLLQNRRLDLDACKARLKKAKAAEAKATVSAPTVPDFQETRPRNYILSASASALWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 334,
                "header": "tr|D4A7V1-1|SHLB2_RAT Computationally mapped isoform of Endophilin-B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=4 CANONICAL=Q5PPJ9-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 13627044,
                "end_pos": 13617447,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000023527.8",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000023527.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000023527.7",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000023527.7"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q5PPJ9-1",
            "url": "",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPNTPYGKTLMKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRAAQTEFDRQAEVTRLLLEGISSAHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 404,
                "header": "sp|Q5PPJ9-1|SHLB2_RAT Isoform 1 of Endophilin-B2  OS=Rattus norvegicus OX=10116 GN=Sh3glb2 PE=1 SV=2 CANONICAL=Q5PPJ9-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "evidence": [
                {
                    "id": "Q5PPJ9",
                    "database": "O-GlcNAc Database",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5PPJ9"
                },
                {
                    "id": "34502162",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/34502162"
                },
                {
                    "id": "18683930",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/18683930"
                }
            ]
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 10,
            "end_pos": 10,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5PPJ9",
                    "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                }
            ],
            "site_lbl": "Ser10"
        },
        {
            "start_pos": 404,
            "end_pos": 404,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5PPJ9",
                    "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                },
                {
                    "database": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q5PPJ9",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5PPJ9"
                }
            ],
            "site_lbl": "Ser404"
        }
    ],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_reported_with_glycan"
    ],
    "publication": [
        {
            "title": "Direct in-gel fluorescence detection and cellular imaging of O-GlcNAc-modified proteins.",
            "journal": "Journal of the American Chemical Society",
            "date": "2008",
            "authors": "Clark PM, Dweck JF, Mason DE, Hart CR, Buck SB, Peters EC, Agnew BJ, Hsieh-Wilson LC",
            "evidence": [
                {
                    "database": "O-GlcNAc Database",
                    "id": "Q5PPJ9",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5PPJ9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18683930",
                    "url": "https://glygen.org/publication/PubMed/18683930"
                }
            ]
        },
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.",
            "journal": "Nature communications",
            "date": "2012",
            "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q5PPJ9",
                    "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                },
                {
                    "database": "UniProtKB",
                    "id": "D4A7V1",
                    "url": "https://www.uniprot.org/uniprot/D4A7V1"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K9P4",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K9P4"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q5PPJ9",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5PPJ9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                }
            ]
        },
        {
            "title": "An O-GlcNAcylomic Approach Reveals ACLY as a Potential Target in Sepsis in the Young Rat.",
            "journal": "International journal of molecular sciences",
            "date": "2021",
            "authors": "Denis M, Dupas T, Persello A, Dontaine J, Bultot L, Betus C, Pele T, Dhot J, Erraud A, Maillard A, Montnach J, Leroux AA, Bigot-Corbel E, Vertommen D, Riviere M, Lebreton J, Tessier A, Waard M, Bertrand L, Rozec B, Lauzier B",
            "evidence": [
                {
                    "database": "O-GlcNAc Database",
                    "id": "Q5PPJ9",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5PPJ9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34502162",
                    "url": "https://glygen.org/publication/PubMed/34502162"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:311848",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:311848",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-264870",
            "name": "Caspase-mediated cleavage of cytoskeletal proteins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-264870",
            "resource": "Reactome",
            "description": "Caspase-mediated cleavage of cytoskeletal proteins"
        },
        {
            "id": "R-RNO-6794361",
            "name": "Neurexins and neuroligins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6794361",
            "resource": "Reactome",
            "description": "Neurexins and neuroligins"
        },
        {
            "id": "R-RNO-6798695",
            "name": "Neutrophil degranulation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6798695",
            "resource": "Reactome",
            "description": "Neutrophil degranulation"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8R3V5-4",
            "protein_name": "Endophilin-B2",
            "gene_name": "Sh3glb2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPSTPYGKTLIKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAVLAPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 400
            },
            "evidence": [
                {
                    "id": "45234295",
                    "url": "http://www.informatics.jax.org/homology/45234295",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9NR46-1",
            "protein_name": "Endophilin-B2",
            "gene_name": "SH3GLB2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS",
                "length": 395
            },
            "evidence": [
                {
                    "id": "45234295",
                    "url": "http://www.informatics.jax.org/homology/45234295",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 7,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "synapse",
                        "id": "GO:0045202",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glutamatergic synapse",
                        "id": "GO:0098978",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "postsynaptic endocytic zone",
                        "id": "GO:0098843",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098843",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleoplasm",
                        "id": "GO:0005654",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "postsynaptic neurotransmitter receptor internalization",
                        "id": "GO:0098884",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098884",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane organization",
                        "id": "GO:0061024",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "identical protein binding",
                        "id": "GO:0042802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q5PPJ9",
                                "url": "https://www.uniprot.org/uniprot/Q5PPJ9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 51,
            "end_pos": 53,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 1
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 1
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "type",
                "subtype",
                "site_category",
                "site_seq",
                "relation",
                "comment"
            ]
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 1
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 1
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "type",
                "subtype",
                "site_category",
                "site_seq",
                "relation",
                "comment"
            ]
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 2
                },
                {
                    "field": "total_sites",
                    "count": 2
                }
            ],
            "sort_fields": [
                "start_pos",
                "end_pos",
                "kinase_uniprot_canonical_ac",
                "kinase_gene_name",
                "residue",
                "comment",
                "site_lbl"
            ]
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 3
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}