{ "uniprot_canonical_ac": "Q558Z9-1", "uniprot_ac": "Q558Z9", "uniprot_id": "EXOC7_DICDI", "mass": { "chemical_mass": 94447.0, "monoisotopic_mass": 94447.0 }, "refseq": { "ac": "XP_644917", "name": "exocyst complex subunit 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644917" }, "gene_names": [ { "name": "exoc7", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q558Z9", "id": "Q558Z9" }, { "name": "DDB_G0272991", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q558Z9", "id": "Q558Z9" }, { "name": "exo70", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q558Z9", "id": "Q558Z9" }, { "name": "exoc7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644917", "id": "XP_644917" } ], "protein_names": [ { "name": "Exocyst complex component 7", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q558Z9" }, { "name": "Exocyst complex component Exo70", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q558Z9" }, { "name": "exocyst complex subunit 7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644917", "id": "XP_644917" } ], "function": [ { "annotation": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "common_name": "Dictyostelium discoideum" } ], "gene": [ { "name": "exoc7", "url": "https://www.uniprot.org/uniprot/Q558Z9", "locus": {} } ], "crossref": [ { "id": "DDB_G0272991", "url": "", "database": "", "categories": [ "Organism-specific" ] }, { "id": "8618596", "url": "https://www.ncbi.nlm.nih.gov/gene/8618596", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ddi:DDB_G0272991", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0272991", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FAVIFEN", "url": "https://omabrowser.org/oma/group/FAVIFEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12542", 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"Q558Z9-1", "url": "https://www.uniprot.org/uniprot/Q558Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAPPRLSARLSVLDQKKSNAPSPTSPTGLKTSLGMPPNSGSSGGGGGLKSSVGISSLPTIPSTKSTSPTLPKRNSANLSLLQQQQQQHTNKSTSPSSNTPTATSTTSPFSYLGKQASAQNLNTMMSMMMLNKNPLSPVVPQPGASLFYATPTEADDEEFEHIRNLLNSEYSVTTVQSTGALKSSNLVVMSWKNNATSELTEQDDQLENDKRDLQFIKEQLEKNNSMSKQMIYILDRFNEGLSQLEMDVAPINASMNEWSSIFNNINSTMEQVKSVLDKFDVDKIDSKINDGAKGDYVSYMLALEHVGNAIDYIAEKSHFKSSDKVMDALKQLKATGLNELETSFKSLLLKISNLVDPTTIAKLPNSKRYLAIILPNHVEEISKYIELFEKLHYNAFLKEYKDKRSKFILLSLRKMAPEKFIKQTSETKNLAYVKGSHPLISYVQETLRLYQIEYDLASELFGNQYQLILDEIIDPAHELLLETTEPIIKVRKTPGDKIFSIFPLLDLFDTFTKLLPDFITAISSRDGKHISELKTQIKHLQDTCASLLDFSLDEEKEISSSNRKEIISDATVDEISSNMINYFKRLIEYKHSVELLLKGQDNNNSNSNSNAPSSTSSNSKSSSSSSSSSSSNSASSTILPTSFIGFLEKILKNLIKYLQGRAKKDFPTQPATDFFKPPIKSVIFQINNYHYISTSLKQSKILSNQQFENNELASANHILHEFETCLDNEIKVLNSFWKTIADILITNKSNKEKDEVKSIIKKHTNFLKTFNDLNKLKFDIPDQELKLKLKTEAKNIIGRSYDQFKELCRLEKIHLEKNFVPFETTDDINRKLDRVFDSQ", "length": 840, "header": "sp|Q558Z9-1|EXOC7_DICDI Isoform 1 of Exocyst complex component 7 OS=Dictyostelium discoideum OX=44689 GN=exoc7 PE=3 SV=1 CANONICAL=Q558Z9-1" }, "isoforms": [ { "isoform_ac": "Q558Z9-1", "url": "", "sequence": { "sequence": "MSAPPRLSARLSVLDQKKSNAPSPTSPTGLKTSLGMPPNSGSSGGGGGLKSSVGISSLPTIPSTKSTSPTLPKRNSANLSLLQQQQQQHTNKSTSPSSNTPTATSTTSPFSYLGKQASAQNLNTMMSMMMLNKNPLSPVVPQPGASLFYATPTEADDEEFEHIRNLLNSEYSVTTVQSTGALKSSNLVVMSWKNNATSELTEQDDQLENDKRDLQFIKEQLEKNNSMSKQMIYILDRFNEGLSQLEMDVAPINASMNEWSSIFNNINSTMEQVKSVLDKFDVDKIDSKINDGAKGDYVSYMLALEHVGNAIDYIAEKSHFKSSDKVMDALKQLKATGLNELETSFKSLLLKISNLVDPTTIAKLPNSKRYLAIILPNHVEEISKYIELFEKLHYNAFLKEYKDKRSKFILLSLRKMAPEKFIKQTSETKNLAYVKGSHPLISYVQETLRLYQIEYDLASELFGNQYQLILDEIIDPAHELLLETTEPIIKVRKTPGDKIFSIFPLLDLFDTFTKLLPDFITAISSRDGKHISELKTQIKHLQDTCASLLDFSLDEEKEISSSNRKEIISDATVDEISSNMINYFKRLIEYKHSVELLLKGQDNNNSNSNSNAPSSTSSNSKSSSSSSSSSSSNSASSTILPTSFIGFLEKILKNLIKYLQGRAKKDFPTQPATDFFKPPIKSVIFQINNYHYISTSLKQSKILSNQQFENNELASANHILHEFETCLDNEIKVLNSFWKTIADILITNKSNKEKDEVKSIIKKHTNFLKTFNDLNKLKFDIPDQELKLKLKTEAKNIIGRSYDQFKELCRLEKIHLEKNFVPFETTDDINRKLDRVFDSQ", "length": 840, "header": "sp|Q558Z9-1|EXOC7_DICDI Isoform 1 of Exocyst complex component 7 OS=Dictyostelium discoideum OX=44689 GN=exoc7 PE=3 SV=1 CANONICAL=Q558Z9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.", "journal": "Nature", "date": "2002", "authors": "Gloeckner G., Kumpf K., Lehmann R., Platzer M., Rosenthal A., Bankier A.T., Dear P.H., Szafranski K., Guigo R., Parra G., Noegel A.A., Glockner G., Tunggal B., Abril J.F., Cox E., Eichinger L., Quail M.A., Cox E.C., Baumgart C., Pachebat J.A.", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "reference": [ { "type": "PubMed", "id": "12097910", "url": "https://glygen.org/publication/PubMed/12097910" } ] }, { "title": "The genome of the social amoeba Dictyostelium discoideum.", "journal": "Nature", "date": "2005", "authors": "Chen G., Gibbs R.A., Gloeckner G., Hernandez J., Johnson D., Knights A., Lehmann R., Loulseged H., Ma J., Muzny D.M., Oliver K., Platzer M., Rosenthal A., Saito T., Sodergren E., Steffen D., Sugano S., Walker D., Weinstock G., Lu M., Muzny D., Tanaka Y., Song J., Sodergren E.J., Xu Q., Bankier A.T., Barrell B.G., Williams J., Fey P., Nie X., Gibbs R., Dear P.H., Szafranski K., Davies R., Price C., James K., Noegel A.A., Glockner G., Cooper J., Morio T., Davis P., Williams J.G., Kay R.R., Cronin A., Schleicher M., Olsen R., Kummerfeld S., Sharp S., Hauser H., Weinstock G.M., White B., Quiles M., Rost R., Tunggal B., Pain A., Madan Babu M., Madera M., Rivero F., Saunders D., Eichinger L., Sanders M., Kohara Y., Chisholm R.L., Barrell B., Churcher C.M., Hamlin N., Rajandream M.A., Thangavelu M., Quail M.A., Anjard C., Cox E.C., Haydock S., Kuspa A., Loomis W.F., Shaulsky G., Sucgang R., Urushihara H., Bason N., Berriman M., Buchrieser C., Churcher C., Desany B., Farbrother P., Felder M., Gaudet P., Goodhead I., Hall N., Harper D., Hemphill L., James K.D., Just E., Kerhornou A., Konfortov B.A., Lindsay R., Mourier T., Mungall K., Mungall K.L., Pachebat J.A., Pilcher K., Rabbinowitsch E., Simmonds M., Simmonds M.N., Spiegler S., Tivey A., Wardroper A., Winckler T., Woodward J., Woodward J.R., van Driessche N.", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "reference": [ { "type": "PubMed", "id": "15875012", "url": "https://glygen.org/publication/PubMed/15875012" } ] } ], "pathway": [ { "id": "ddi:DDB_G0272991", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0272991", "resource": "KEGG Pathway" }, { "id": "R-DDI-264876", "name": "Insulin processing", "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-264876", "resource": "Reactome", "description": "Insulin processing" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q558Z9", "url": "https://www.uniprot.org/uniprot/Q558Z9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, 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