{
    "uniprot_canonical_ac": "Q4V899-1",
    "uniprot_ac": "Q4V899",
    "uniprot_id": "TM165_RAT",
    "mass": {
        "chemical_mass": 34810.0,
        "monoisotopic_mass": 34810.0
    },
    "refseq": {
        "ac": "NP_001019973",
        "name": "transmembrane protein 165 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019973"
    },
    "gene_names": [
        {
            "name": "Tmem165",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q4V899",
            "id": "Q4V899"
        },
        {
            "name": "Tmem165",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019973",
            "id": "NP_001019973"
        },
        {
            "name": "Tparl",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019973",
            "id": "NP_001019973"
        },
        {
            "name": "Tparl",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q4V899",
            "id": "Q4V899"
        }
    ],
    "protein_names": [
        {
            "name": "Transmembrane protein 165",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q4V899"
        },
        {
            "name": "Transmembrane protein TPARL",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q4V899"
        },
        {
            "name": "transmembrane protein 165 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019973",
            "id": "NP_001019973"
        },
        {
            "name": "transmembrane protein TPARL; TPA regulated locus",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019973",
            "id": "NP_001019973"
        }
    ],
    "function": [
        {
            "annotation": "May function as a calcium/proton transporter involved in calcium and in lysosomal pH homeostasis. Therefore, it may play an indirect role in protein glycosylation (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q4V899",
                    "url": "https://www.uniprot.org/uniprot/Q4V899#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050571",
            "recommended_name": {
                "id": "DOID:0050571",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050571",
                "name": "congenital disorder of glycosylation type II",
                "description": "A congenital disorder of glycosylation that involves malfunctioning trimming or processing of the protein-bound oligosaccharide chain."
            },
            "synonyms": [
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "MGAT2-congenital disorder of glycosylation",
                    "description": "MGAT2-CDG is a form of congenital disorders of N-linked glycosylation characterized by facial dysmorphism (large, posteriorly rotated ears with prominent antihelices, convex nasal ridge, open mouth, large and crowded teeth), stereotypic hand movements, seizures, and varying degrees of developmental delay. A bleeding tendency is also observed and this results from diminished platelet aggregation. The disease is caused by loss-of-function mutations in the gene MGAT2 (14q21)."
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "CDG syndrome type IIa",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "CDG-IIa",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "CDG2A",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "MGAT2-CDG",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "N-acetylglucosaminyltransferase 2 deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "carbohydrate deficient glycoprotein syndrome type IIa",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "congenital disorder of glycosylation type 2a",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "congenital disorder of glycosylation type IIa",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "Alkuraya syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "CDG 2A",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "CDG IIa",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "CDGS2",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "MGAT2-CDG (CDG-IIa)",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "carbohydrate-deficient glycoprotein syndrome type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "carbohydrate-deficient glycoprotein syndrome, type II",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "carbohydrate-deficient glycoprotein syndrome, type II, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "carbohydrate-deficient glycoprotein syndrome, type II, formerly; CDGS2, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "congenital disorder of glycosylation, type IIa",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "intellectual disability, Growth retardation, prominent columella, and open mouth",
                    "description": ""
                },
                {
                    "id": "MONDO:0008908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008908",
                    "name": "mental retardation, Growth retardation, prominent columella, and open mouth",
                    "description": ""
                },
                {
                    "id": "MIM:212066",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/212066",
                    "name": "Congenital disorder of glycosylation 2A",
                    "description": "Congenital disorder of glycosylation 2A"
                }
            ],
            "evidence": [
                {
                    "id": "0050571",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050571"
                }
            ]
        },
        {
            "disease_id": "DOID:0070263",
            "recommended_name": {
                "id": "DOID:0070263",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0070263",
                "name": "congenital disorder of glycosylation type IIk",
                "description": "A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the TMEM165 gene on chromosome 4q12."
            },
            "synonyms": [
                {
                    "id": "DOID:0070263",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0070263",
                    "name": "CDG IIk",
                    "description": ""
                },
                {
                    "id": "DOID:0070263",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0070263",
                    "name": "CDG syndrome type IIk",
                    "description": ""
                },
                {
                    "id": "DOID:0070263",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0070263",
                    "name": "CDG2K",
                    "description": ""
                },
                {
                    "id": "DOID:0070263",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0070263",
                    "name": "CDGIIdk",
                    "description": ""
                },
                {
                    "id": "DOID:0070263",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0070263",
                    "name": "Congenital disorder of glycosylation type 2k",
                    "description": ""
                },
                {
                    "id": "DOID:0070263",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0070263",
                    "name": "Carbohydrate deficient glycoprotein syndrome type IIk",
                    "description": ""
                },
                {
                    "id": "DOID:0070263",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0070263",
                    "name": "TMEM165-CDG",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "TMEM165-congenital disorder of glycosylation",
                    "description": "TMEM165-CDG is a form of congenital disorders of N-linked glycosylation characterized by a psychomotor delay-dysmorphism (pectus carinatum, dorsolumbar kyphosis and severe sinistroconvex scoliosis, short distal phalanges, genua vara, pedes planovalgi syndrome) with postnatal growth deficiency and major spondylo-, epi-, and metaphyseal skeletal involvement. Additional features include facial dysmorphism (midface hypoplasia, internal strabism of the right eye, low-set ears, moderately high arched palate, small teeth), nephrotic syndrome, cardiac defects, and feeding problems. The disease is caused by mutations in the gene TMEM165 (4q12)."
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "CDG syndrome type IIk",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "CDG-IIk",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "CDG2K",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "TMEM165-CDG",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "TMEM165-congenital disorder of glycosylation",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "carbohydrate deficient glycoprotein syndrome type IIk",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "congenital disorder of glycosylation type 2k",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "congenital disorder of glycosylation type IIk",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "CDG IIk",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "TMEM165-CDG (CDG-IIk)",
                    "description": ""
                },
                {
                    "id": "MONDO:0013870",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013870",
                    "name": "congenital disorder of glycosylation, type IIk",
                    "description": ""
                },
                {
                    "id": "MIM:614727",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/614727",
                    "name": "Congenital disorder of glycosylation 2K",
                    "description": "Congenital disorder of glycosylation 2K"
                }
            ],
            "evidence": [
                {
                    "id": "0070263",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070263"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q4V899",
                    "url": "https://www.uniprot.org/uniprot/Q4V899"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Tmem165",
            "url": "https://www.uniprot.org/uniprot/Q4V899",
            "locus": {
                "chromosome": "14",
                "start_pos": 31993493,
                "end_pos": 32018717,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000002199",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000002199"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000002199",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000002199",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "364137",
            "url": "https://www.ncbi.nlm.nih.gov/gene/364137",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001727",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001727",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:364137",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:364137",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "VWSLWEA",
            "url": "https://omabrowser.org/oma/group/VWSLWEA/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "180756at2759",
            "url": "http://www.orthodb.org/?query=180756at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12608",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12608",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12608:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12608:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01169",
            "url": "http://pfam.xfam.org/family/PF01169",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q4V899",
            "url": "http://purl.obolibrary.org/obo/PR_Q4V899",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001019973",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019973",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1306983",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306983",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "Q4V899",
            "url": "https://www.uniprot.org/uniprot/Q4V899",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q4V899-1",
            "url": "https://www.uniprot.org/uniprot/Q4V899-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAASARGSGRAPTRRLLVLLLLPLLWAPAGVRAGPEEDLSHRNQEPPAPAQQLQPQPAAVQGLEPARAEKGFTPAAPVHTNREDAATQANLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALALMTCLSVLFGYATTVIPRVYTYYVSTALFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPDVETGTSTAIPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTVTIIGGIVFLAFAFSALFISPESGF",
        "length": 323,
        "header": "sp|Q4V899-1|TM165_RAT Isoform 1 of Transmembrane protein 165  OS=Rattus norvegicus OX=10116 GN=Tmem165 PE=2 SV=1 CANONICAL=Q4V899-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q4V899-1",
            "url": "",
            "sequence": {
                "sequence": "MAASARGSGRAPTRRLLVLLLLPLLWAPAGVRAGPEEDLSHRNQEPPAPAQQLQPQPAAVQGLEPARAEKGFTPAAPVHTNREDAATQANLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALALMTCLSVLFGYATTVIPRVYTYYVSTALFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPDVETGTSTAIPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTVTIIGGIVFLAFAFSALFISPESGF",
                "length": 323,
                "header": "sp|Q4V899-1|TM165_RAT Isoform 1 of Transmembrane protein 165  OS=Rattus norvegicus OX=10116 GN=Tmem165 PE=2 SV=1 CANONICAL=Q4V899-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 32018509,
                "end_pos": 31994187,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000003010",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000003010"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000003010",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000003010"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:364137",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:364137",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P38301-1",
            "protein_name": "GCR1-dependent translation factor 1",
            "gene_name": "GDT1",
            "tax_id": 559292,
            "organism": "Saccharomyces cerevisiae S288C",
            "sequence": {
                "sequence": "MGNMIKKASLIALLPLFTAAAAAATDAETSMESGSSSHLKSFLMSVSMIGLSEIGDKTFLIAALMAMRHKRVLVFSAAATSLAIMTILSGVVGHSAVAFLSERYTAFFAGILFLVFGYKLTMEGLEMSKDAGVEEEMAEVEEEIAIKDMNQDMDDVEKGGDTAYDKQLKNASIGKKIVHRIRELASFMFSPVWVQIFLMVFLGELGDRSQISIIAMATDSDYWYVIAGAVIGHAICSGLAVVGGKLLATRISIRTITLASSLLFFIFALMYIYQAFTTQD",
                "length": 280
            },
            "evidence": [
                {
                    "id": "Q4V899",
                    "url": "https://omabrowser.org/oma/group/Q4V899/",
                    "database": "OMA"
                }
            ],
            "common_name": "Yeast"
        },
        {
            "uniprot_canonical_ac": "P52875-1",
            "protein_name": "Transmembrane protein 165",
            "gene_name": "Tmem165",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MAAAARGSGRAPTRRLLVLLLLQLLWAPAGVRAGPEEDLSHRNQEPPAPAQQLQPQPAAVQGLEPARAEKGLTPVAPVHTNKEDAAAQTNLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALALMTCLSVLFGYATTVIPRVYTYYVSTALFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPDVETGTSTAIPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTVTIIGGIVFLAFAFSALFISPESGF",
                "length": 323
            },
            "evidence": [
                {
                    "id": "45235711",
                    "url": "http://www.informatics.jax.org/homology/45235711",
                    "database": "MGI"
                },
                {
                    "id": "Q4V899",
                    "url": "https://omabrowser.org/oma/group/Q4V899/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9HC07-1",
            "protein_name": "Transmembrane protein 165",
            "gene_name": "TMEM165",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAAAAPGNGRASAPRLLLLFLVPLLWAPAAVRAGPDEDLSHRNKEPPAPAQQLQPQPVAVQGPEPARVEKIFTPAAPVHTNKEDPATQTNLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALGLMTCLSVLFGYATTVIPRVYTYYVSTVLFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPGDVETGTSITVPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTVTIIGGIVFLAFAFSALFISPDSGF",
                "length": 324
            },
            "evidence": [
                {
                    "id": "45235711",
                    "url": "http://www.informatics.jax.org/homology/45235711",
                    "database": "MGI"
                },
                {
                    "id": "Q4V899",
                    "url": "https://omabrowser.org/oma/group/Q4V899/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 7,
                "go_terms": [
                    {
                        "name": "Golgi membrane",
                        "id": "GO:0000139",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi apparatus",
                        "id": "GO:0005794",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "trans-Golgi network membrane",
                        "id": "GO:0032588",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lysosomal membrane",
                        "id": "GO:0005765",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "late endosome membrane",
                        "id": "GO:0031902",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "early endosome membrane",
                        "id": "GO:0031901",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endosome membrane",
                        "id": "GO:0010008",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "intracellular calcium ion homeostasis",
                        "id": "GO:0006874",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein N-linked glycosylation",
                        "id": "GO:0006487",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "calcium ion transmembrane transport",
                        "id": "GO:0070588",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi calcium ion homeostasis",
                        "id": "GO:0032468",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032468",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi calcium ion transport",
                        "id": "GO:0032472",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032472",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "manganese ion transmembrane transport",
                        "id": "GO:0071421",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071421",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of lysosomal lumen pH",
                        "id": "GO:0035751",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035751",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "calcium ion transmembrane transporter activity",
                        "id": "GO:0015085",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015085",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "manganese ion transmembrane transporter activity",
                        "id": "GO:0005384",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005384",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4V899",
                                "url": "https://www.uniprot.org/uniprot/Q4V899"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
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                },
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                    "field": "total_sites",
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                {
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                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
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                {
                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
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                    "field": "n_linked_glycan_sites",
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                {
                    "field": "o_linked_glycan_sites",
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            ],
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        },
        {
            "table_id": "phosphorylation",
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                    "field": "total",
                    "count": 0
                },
                {
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
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                {
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            ],
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        {
            "table_id": "snv_disease",
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                    "field": "total_sites",
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            ],
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        {
            "table_id": "snv_non_disease",
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        {
            "table_id": "publication",
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    ]
}