{
    "uniprot_canonical_ac": "Q4FZU2-1",
    "uniprot_ac": "Q4FZU2",
    "uniprot_id": "K2C6A_RAT",
    "mass": {
        "chemical_mass": 59249.0,
        "monoisotopic_mass": 59249.0
    },
    "refseq": {
        "ac": "NP_001094477",
        "name": "keratin, type II cytoskeletal 6A",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094477"
    },
    "gene_names": [
        {
            "name": "Krt6a",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q4FZU2",
            "id": "Q4FZU2"
        },
        {
            "name": "CK-6A; Krt6a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094477",
            "id": "NP_001094477"
        },
        {
            "name": "Krt6c",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094477",
            "id": "NP_001094477"
        }
    ],
    "protein_names": [
        {
            "name": "Keratin, type II cytoskeletal 6A",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q4FZU2"
        },
        {
            "name": "CK-6A",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q4FZU2"
        },
        {
            "name": "Cytokeratin-6A",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q4FZU2"
        },
        {
            "name": "K6A",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q4FZU2"
        },
        {
            "name": "Keratin-6A",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q4FZU2"
        },
        {
            "name": "Type-II keratin Kb6",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q4FZU2"
        },
        {
            "name": "keratin K6; K6a keratin; cytokeratin-6A; type-II keratin Kb6; keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 5-like",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094477",
            "id": "NP_001094477"
        },
        {
            "name": "keratin, type II cytoskeletal 6A",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094477",
            "id": "NP_001094477"
        }
    ],
    "function": [
        {
            "annotation": "Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q4FZU2",
                    "url": "https://www.uniprot.org/uniprot/Q4FZU2#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "P50446",
                    "url": "https://www.uniprot.org/uniprot/P50446#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050449",
            "recommended_name": {
                "id": "DOID:0050449",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050449",
                "name": "pachyonychia congenita",
                "description": "A syndrome that is characterized by hypertrophic nails and hyperkeratosis of the hands and feet and has_material_basis_in gene mutations that result in changes in keratin."
            },
            "synonyms": [
                {
                    "id": "DOID:0050449",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050449",
                    "name": "Jackson-Lawler Type Pachyonychia Congenita",
                    "description": ""
                },
                {
                    "id": "DOID:0050449",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050449",
                    "name": "Jadassohn-Lewandowsky Syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0050449",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050449",
                    "name": "PACHYONYCHIA CONGENITA, JADASSOHN-LEWANDOWSKY TYPE",
                    "description": ""
                },
                {
                    "id": "DOID:0050449",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050449",
                    "name": "Pachyonychia Congenita Type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita 1",
                    "description": "Any pachyonychia congenita in which the cause of the disease is a mutation in the KRT16 gene."
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "KRT16 pachyonychia congenita",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita caused by mutation in KRT16",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "Jadassohn-Lewandowsky syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "Jadassohn-Lewandowsky syndrome, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "PC1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita, Jadassohn-Lewandowsky type",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita, Jadassohn-Lewandowsky type, formerly",
                    "description": ""
                },
                {
                    "id": "MIM:167200",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/167200",
                    "name": "Pachyonychia congenita 1",
                    "description": "Pachyonychia congenita 1"
                }
            ],
            "evidence": [
                {
                    "id": "0050449",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050449"
                }
            ]
        },
        {
            "disease_id": "DOID:0111710",
            "recommended_name": {
                "id": "DOID:0111710",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111710",
                "name": "focal or diffuse nonepidermolytic palmoplantar keratoderma",
                "description": "A nonepidermolytic palmoplantar keratoderma characterized by focal or diffuse palmoplantar keratodermas with minor or absent nail changes that has_material_basis_in heterozygous mutation in the KRT6C gene on chromosome 12q13.13."
            },
            "synonyms": [
                {
                    "id": "DOID:0111710",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111710",
                    "name": "PPKNEFD",
                    "description": ""
                },
                {
                    "id": "DOID:0111710",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111710",
                    "name": "autosomal dominant focal non-epidermolytic palmoplantar keratoderma with plantar blistering",
                    "description": ""
                },
                {
                    "id": "MONDO:0014327",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014327",
                    "name": "palmoplantar keratoderma, nonepidermolytic, focal or diffuse",
                    "description": ""
                },
                {
                    "id": "MONDO:0014327",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014327",
                    "name": "autosomal dominant focal non-epidermolytic palmoplantar keratoderma with plantar blistering",
                    "description": ""
                },
                {
                    "id": "MONDO:0014327",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014327",
                    "name": "palmoplantar keratoderma, nonepidermolytic, focal or diffuse",
                    "description": ""
                },
                {
                    "id": "MONDO:0014327",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014327",
                    "name": "PPKNEFD",
                    "description": ""
                },
                {
                    "id": "MIM:615735",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/615735",
                    "name": "Palmoplantar keratoderma, non-epidermolytic, focal or diffuse",
                    "description": "Palmoplantar keratoderma, non-epidermolytic, focal or diffuse"
                }
            ],
            "evidence": [
                {
                    "id": "0111710",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111710"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q4FZU2",
                    "url": "https://www.uniprot.org/uniprot/Q4FZU2"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Krt6a",
            "url": "https://www.uniprot.org/uniprot/Q4FZU2",
            "locus": {
                "chromosome": "7",
                "start_pos": 132829278,
                "end_pos": 132833714,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000068586",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000068586"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "683313",
            "url": "https://www.ncbi.nlm.nih.gov/gene/683313",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR003054",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003054",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018039",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR032444",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032444",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR039008",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:683313",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:683313",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "Q4FZU2",
            "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q4FZU2",
            "database": "O-GlcNAc Database",
            "categories": [
                "Glycoproteomics"
            ]
        },
        {
            "id": "TTEGSHI",
            "url": "https://omabrowser.org/oma/group/TTEGSHI/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4640531at2759",
            "url": "http://www.orthodb.org/?query=4640531at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR45616",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR45616:SF39",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF39",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00038",
            "url": "http://pfam.xfam.org/family/PF00038",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF16208",
            "url": "http://pfam.xfam.org/family/PF16208",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q4FZU2",
            "url": "http://purl.obolibrary.org/obo/PR_Q4FZU2",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-RNO-6805567",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6805567",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-6809371",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6809371",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001094477",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094477",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1588056",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1588056",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "Q4FZU2",
            "url": "https://www.uniprot.org/uniprot/Q4FZU2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q4FZU2-1",
            "url": "https://www.uniprot.org/uniprot/Q4FZU2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSTKTVIRSQTSHRGFSAGSARLPGLNRSGFSSVSVCRSRGSGGSRAVCGGAGFGSRSLCGVGSSQRISIGGGSCGIGGGYGGRFGGSFGYGGGAGGSLGFGAGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLTPMNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQGLETLFEQYINDLRKELDNILGQRGRLDSELRNMQGTVEDYKSKYEDEINRRTAAENEFVTLKKDVDAAYMNKVELQAKADSLTDEINFLRALYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIAKRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEISEINRMIQRLRSEIDHVKKQIANLQAAIAEAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQDLMNVKLALDVEIATYRTLLEGEECRLNGEGVGPVNISVVQSTVSSSYGSAGGASSSIGLGGSSSFSYGGSHSIGGGFSAGSGRGISSGLSSSGGSSSTIKYTTTSSTRKSYRP",
        "length": 552,
        "header": "sp|Q4FZU2-1|K2C6A_RAT Isoform 1 of Keratin, type II cytoskeletal 6A  OS=Rattus norvegicus OX=10116 GN=Krt6a PE=1 SV=1 CANONICAL=Q4FZU2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q4FZU2-1",
            "url": "",
            "sequence": {
                "sequence": "MSTKTVIRSQTSHRGFSAGSARLPGLNRSGFSSVSVCRSRGSGGSRAVCGGAGFGSRSLCGVGSSQRISIGGGSCGIGGGYGGRFGGSFGYGGGAGGSLGFGAGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLTPMNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQGLETLFEQYINDLRKELDNILGQRGRLDSELRNMQGTVEDYKSKYEDEINRRTAAENEFVTLKKDVDAAYMNKVELQAKADSLTDEINFLRALYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIAKRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEISEINRMIQRLRSEIDHVKKQIANLQAAIAEAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQDLMNVKLALDVEIATYRTLLEGEECRLNGEGVGPVNISVVQSTVSSSYGSAGGASSSIGLGGSSSFSYGGSHSIGGGFSAGSGRGISSGLSSSGGSSSTIKYTTTSSTRKSYRP",
                "length": 552,
                "header": "sp|Q4FZU2-1|K2C6A_RAT Isoform 1 of Keratin, type II cytoskeletal 6A  OS=Rattus norvegicus OX=10116 GN=Krt6a PE=1 SV=1 CANONICAL=Q4FZU2-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 132804012,
                "end_pos": 132800141,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000102479",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000102479"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000087976",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000087976"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "evidence": [
                {
                    "id": "Q4FZU2",
                    "database": "O-GlcNAc Database",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q4FZU2"
                },
                {
                    "id": "34502162",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/34502162"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_reported_with_glycan"
    ],
    "publication": [
        {
            "title": "An O-GlcNAcylomic Approach Reveals ACLY as a Potential Target in Sepsis in the Young Rat.",
            "journal": "International journal of molecular sciences",
            "date": "2021",
            "authors": "Denis M, Dupas T, Persello A, Dontaine J, Bultot L, Betus C, Pele T, Dhot J, Erraud A, Maillard A, Montnach J, Leroux AA, Bigot-Corbel E, Vertommen D, Riviere M, Lebreton J, Tessier A, Waard M, Bertrand L, Rozec B, Lauzier B",
            "evidence": [
                {
                    "database": "O-GlcNAc Database",
                    "id": "Q4FZU2",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q4FZU2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34502162",
                    "url": "https://glygen.org/publication/PubMed/34502162"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:683313",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:683313",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-6805567",
            "name": "Keratinization",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6805567",
            "resource": "Reactome",
            "description": "Keratinization"
        },
        {
            "id": "R-RNO-6809371",
            "name": "Formation of the cornified envelope",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6809371",
            "resource": "Reactome",
            "description": "Formation of the cornified envelope"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P02538-1",
            "protein_name": "Keratin, type II cytoskeletal 6A",
            "gene_name": "KRT6A",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYKH",
                "length": 564
            },
            "evidence": [
                {
                    "id": "45224093",
                    "url": "http://www.informatics.jax.org/homology/45224093",
                    "database": "MGI"
                },
                {
                    "id": "45224102",
                    "url": "http://www.informatics.jax.org/homology/45224102",
                    "database": "MGI"
                },
                {
                    "id": "45224109",
                    "url": "http://www.informatics.jax.org/homology/45224109",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04259-1",
            "protein_name": "Keratin, type II cytoskeletal 6B",
            "gene_name": "KRT6B",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVGGGSSTIKYTTTSSSSRKSYKH",
                "length": 564
            },
            "evidence": [
                {
                    "id": "45224093",
                    "url": "http://www.informatics.jax.org/homology/45224093",
                    "database": "MGI"
                },
                {
                    "id": "45224102",
                    "url": "http://www.informatics.jax.org/homology/45224102",
                    "database": "MGI"
                },
                {
                    "id": "45224109",
                    "url": "http://www.informatics.jax.org/homology/45224109",
                    "database": "MGI"
                },
                {
                    "id": "Q4FZU2",
                    "url": "https://omabrowser.org/oma/group/Q4FZU2/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P48668-1",
            "protein_name": "Keratin, type II cytoskeletal 6C",
            "gene_name": "KRT6C",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYKH",
                "length": 564
            },
            "evidence": [
                {
                    "id": "45224093",
                    "url": "http://www.informatics.jax.org/homology/45224093",
                    "database": "MGI"
                },
                {
                    "id": "45224102",
                    "url": "http://www.informatics.jax.org/homology/45224102",
                    "database": "MGI"
                },
                {
                    "id": "45224109",
                    "url": "http://www.informatics.jax.org/homology/45224109",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P50446-1",
            "protein_name": "Keratin, type II cytoskeletal 6A",
            "gene_name": "Krt6a",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSTKTTIKSQTSHRGYSASSARVPGLNRSGFSSVSVCRSRGSGGSSAMCGGAGFGSRSLYGVGSSKRISIGGGSCGIGGGYGSRFGGSFGIGGGAGSGFGFGGGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLTPLNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQNLEPMFEQYISNLRRQLDSIIGERGRLDSELRNMQDTVEDYKSKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADSLTDDINFLRALYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEDIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGPVNISVVQSTVSSGYGSAGGASSSLGLGGGSSYSYSSSHGLGGGFSAGSGRAIGGGLSSSGGLSSSTIKYTTTSSSKKSYRQ",
                "length": 553
            },
            "evidence": [
                {
                    "id": "45224109",
                    "url": "http://www.informatics.jax.org/homology/45224109",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q6IFZ8-1",
            "protein_name": "Predicted gene 5414",
            "gene_name": "Gm5414",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSTQTTIKSQTSHCGSSASSARVPGLNHSGFSCVSLCQSRGISGSGPMCRVASFGSRSLYSEGSSKRISIGGSSCGNREFYGRHYGGDLGIGRGACGCFGFGAGAGFGDGYGGAGFPGYPSGGIQEVTISQSLLIPLNLQIDPTIQRVRTEEREQIKTLNNRFASFIDKVQFLEQQNKVLDTKWALLQEQGTKTVKPEVETLFEDYINILSRRLGFTVAEKGHLDAELRRSQGVLEDYKYKYEDEISKRTAAENEFLTLKKDADAAFMIENELTAKVHSLIDEINFLRTLFDAEMSQMQTPLSDTSVIISMDNNHSLDMESIIAEVKTQYENIAKKSQAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDARGKLEGLKDAPQKAKQDRTRLQKEYQELLSVNIYLDVEITTYRKLLEGEENRFNGEGIGPVNISVVPSTGSSGYDSAGGANRNHGLGGGSSHSYGRNHGLGGGFSTGRSRGIGGGLGSSSGSSSTIKYTTTSSSRKSNRH",
                "length": 552
            },
            "evidence": [
                {
                    "id": "45224093",
                    "url": "http://www.informatics.jax.org/homology/45224093",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9Z331-1",
            "protein_name": "Keratin, type II cytoskeletal 6B",
            "gene_name": "Krt6b",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSTKTTIKSQTSHRGYSASSARVPGLNRSGFSSVSVCRSRGSGGSSAMCGGAGFGSRSLYGVGSSKRISIGGGSCGIGGGYGSRFGGAYGSRFGGSFGIGGGAGSGFGFGGGVGFGGGYGGAGFPVCPPGGIQEVTINQNLLTPLNVQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQNLEPMFEQYISNLRRQLDSIIGERGRLDSELRNMQDTVEDYKSKYEDEINKRTKAENEFVTVKKDVDAAYMTKVELQAKADSLADEINFLRVIYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEDIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDARGKLEGLEDALQKAKQEMARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGPVNISVVQSTVSSGYGSAGGASSSLGLGGSSSYSYGSSHGLGGGFSAGSGRAIGGGLSSSGGLSSSTIKYTTSASSSRKSYRH",
                "length": 562
            },
            "evidence": [
                {
                    "id": "45224102",
                    "url": "http://www.informatics.jax.org/homology/45224102",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 5,
                "go_terms": [
                    {
                        "name": "keratinization",
                        "id": "GO:0031424",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4FZU2",
                                "url": "https://www.uniprot.org/uniprot/Q4FZU2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "intermediate filament organization",
                        "id": "GO:0045109",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4FZU2",
                                "url": "https://www.uniprot.org/uniprot/Q4FZU2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "wound healing",
                        "id": "GO:0042060",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4FZU2",
                                "url": "https://www.uniprot.org/uniprot/Q4FZU2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "intermediate filament cytoskeleton organization",
                        "id": "GO:0045104",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045104",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4FZU2",
                                "url": "https://www.uniprot.org/uniprot/Q4FZU2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "morphogenesis of an epithelium",
                        "id": "GO:0002009",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4FZU2",
                                "url": "https://www.uniprot.org/uniprot/Q4FZU2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "keratin filament",
                        "id": "GO:0045095",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4FZU2",
                                "url": "https://www.uniprot.org/uniprot/Q4FZU2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "structural constituent of skin epidermis",
                        "id": "GO:0030280",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q4FZU2",
                                "url": "https://www.uniprot.org/uniprot/Q4FZU2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 130,
            "end_pos": 132,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 27,
            "end_pos": 29,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 314,
            "end_pos": 316,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 474,
            "end_pos": 476,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
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                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 1
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                {
                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": [
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                "site_seq",
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        },
        {
            "table_id": "glycosylation_reported",
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            "sort_fields": []
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        {
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        {
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                    "field": "total",
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                {
                    "field": "total_sites",
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                {
                    "field": "o_linked_glycan_sites",
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            "sort_fields": []
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        {
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        {
            "table_id": "phosphorylation",
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                    "field": "total",
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                {
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            ],
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        {
            "table_id": "snv",
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        {
            "table_id": "snv_disease",
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        {
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        {
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    ]
}