{ "uniprot_canonical_ac": "Q499V8-1", "uniprot_ac": "Q499V8", "uniprot_id": "SARG_RAT", "mass": { "chemical_mass": 64612.0, "monoisotopic_mass": 64612.0 }, "refseq": { "ac": "NP_001094258", "name": "specifically androgen-regulated gene protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094258" }, "gene_names": [ { "name": "Sarg", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q499V8", "id": "Q499V8" }, { "name": "C13h1orf116", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094258", "id": "NP_001094258" }, { "name": "Sarg", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094258", "id": "NP_001094258" } ], "protein_names": [ { "name": "Specifically androgen-regulated gene protein", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q499V8" }, { "name": "specifically androgen-regulated gene protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094258", "id": "NP_001094258" } ], "function": [ { "annotation": "Putative androgen-specific receptor.", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" } ], "common_name": "Rat" } ], "gene": [ { "name": "Sarg", "url": "https://www.uniprot.org/uniprot/Q499V8", "locus": {} } ], "crossref": [ { "id": "ENSRNOG00000004341", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000004341", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "498222", "url": "https://www.ncbi.nlm.nih.gov/gene/498222", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:498222", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:498222", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NSHTPGE", "url": "https://omabrowser.org/oma/group/NSHTPGE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5322942at2759", "url": "http://www.orthodb.org/?query=5322942at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21555", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21555", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21555:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21555:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15385", "url": "http://pfam.xfam.org/family/PF15385", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q499V8", "url": "http://purl.obolibrary.org/obo/PR_Q499V8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001094258", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094258", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1565034", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1565034", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q499V8-1", "url": "https://www.uniprot.org/uniprot/Q499V8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKRELWPAGSCSEPVTHIGSCGSMMSTTSTHSGSSDSSYDFLSAEEKECLLFLEKTIGSLEAEADSGLSTDESEPATSPQSFRALPTTTQRAPQGKPEARDTQQVPVPVPKRAAQSSGPPESPSPGLRSGSYSLPRNLHLGRSQNLRKSATQTNSVSEAPEVFLEEPKKGQTRQGAKTIQPPAPSQEGTPDLNTVLIPPPEAFQDITSKKAEGESPPKKPGEQTHRPQGHILERSPHSQKKADMSSETMTHKATEKGWTEGPQRPQQPPTQPSQNTQAEEPSLPSGVKPNIQQSLLTATKPRRLPPNIVLKSSRSSFHSHPQNWLSNHTEATDSGPVSSLQEQRKARREALEKLGLPQDQDDPSLPVNKHTGSFKVKEAQAQTSSQARAPAQPASPALVRGTASVAEKASSVKAITPLDSLSKGWIPAQETPPGKVGAAKSMPIPIPKASKENSSLTQSKPDPRLTLQESSIPGLRQMNFKSNTLERSGVGLSSYLSAAEKDPGGQTSTSLGKSPFLDKVSSSVFRNSRPRPASLGMGKDFAGIQGGKLVGLEQGQCSQQPSFKGQSHDKLPRPPCVSVKISPKGIPDGHRREALKKLGLLKE", "length": 604, "header": "sp|Q499V8-1|SARG_RAT Isoform 1 of Specifically androgen-regulated gene protein OS=Rattus norvegicus OX=10116 GN=Sarg PE=1 SV=2 CANONICAL=Q499V8-1" }, "isoforms": [ { "isoform_ac": "Q499V8-1", "url": "", "sequence": { "sequence": "MPKRELWPAGSCSEPVTHIGSCGSMMSTTSTHSGSSDSSYDFLSAEEKECLLFLEKTIGSLEAEADSGLSTDESEPATSPQSFRALPTTTQRAPQGKPEARDTQQVPVPVPKRAAQSSGPPESPSPGLRSGSYSLPRNLHLGRSQNLRKSATQTNSVSEAPEVFLEEPKKGQTRQGAKTIQPPAPSQEGTPDLNTVLIPPPEAFQDITSKKAEGESPPKKPGEQTHRPQGHILERSPHSQKKADMSSETMTHKATEKGWTEGPQRPQQPPTQPSQNTQAEEPSLPSGVKPNIQQSLLTATKPRRLPPNIVLKSSRSSFHSHPQNWLSNHTEATDSGPVSSLQEQRKARREALEKLGLPQDQDDPSLPVNKHTGSFKVKEAQAQTSSQARAPAQPASPALVRGTASVAEKASSVKAITPLDSLSKGWIPAQETPPGKVGAAKSMPIPIPKASKENSSLTQSKPDPRLTLQESSIPGLRQMNFKSNTLERSGVGLSSYLSAAEKDPGGQTSTSLGKSPFLDKVSSSVFRNSRPRPASLGMGKDFAGIQGGKLVGLEQGQCSQQPSFKGQSHDKLPRPPCVSVKISPKGIPDGHRREALKKLGLLKE", "length": 604, "header": "sp|Q499V8-1|SARG_RAT Isoform 1 of Specifically androgen-regulated gene protein OS=Rattus norvegicus OX=10116 GN=Sarg PE=1 SV=2 CANONICAL=Q499V8-1" }, "locus": { "chromosome": "13", "start_pos": 42200696, "end_pos": 42194342, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000005791", "url": "https://www.ensembl.org/id/ENSRNOT00000005791" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000005791", "url": "https://www.ensembl.org/id/ENSRNOP00000005791" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 132, "end_pos": 132, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" } ], "site_lbl": "Ser132" }, { "start_pos": 134, "end_pos": 134, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" } ], "site_lbl": "Ser134" }, { "start_pos": 333, "end_pos": 333, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" } ], "site_lbl": "Thr333" }, { "start_pos": 396, "end_pos": 396, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "Q499V8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q499V8" } ], "site_lbl": "Ser396" }, { "start_pos": 411, "end_pos": 411, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" } ], "site_lbl": "Ser411" }, { "start_pos": 522, "end_pos": 522, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" } ], "site_lbl": "Ser522" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nature communications", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" }, { "database": "iPTMnet", "id": "Q499V8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q499V8" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] } ], "pathway": [ { "id": "rno:498222", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:498222", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8BI29-1", "protein_name": "Specifically androgen-regulated gene protein", "gene_name": "Sarg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKRELWPAGLCSEPVTHIGSCGDMMSTTSTRSGSSDSSYDFLSAEEKECLLFLEKTIGSLEAEADSGLSTDESEPATSPRSFRALPTATQQAPQGKPEATDIQQVPVPKRVAQPSCPPESHSLGLRAGSYSLPRNLHLGRSQNLRESATQANSPVSEASEVFLEEPEKGQTSQGAKAKTIQPPAPSQKGTLDLSTVLIPPPEAFQDIRPKESGEESPPKKPGEQTHTPQVHSLERSPHSQKKVEMSSETVSHKATEKGWTEGLQQPQQPPAQSSQPTKAEELSLPSGVKPSIQQTPLTASKARKLPPNIVLKSSRSSFHSHPQNWLSNHTEATDSGPVSSLQEQRKARREALEKLGLPQDQDDPSLLVNKHTSTLKVREAQPQTPSQARAPARPASPALVSGTASAAGKVSPKKAVAPMDSLSKGWIPTQETPPGKVAEAKSMPIPIPKTLKENSSRTQPKPDPRLTLQESSIPGLRQMNFKSNTLERSGVGLSSYLSAAEKKDPSCQTSTSLGKSPFLDKVSPSAFRNSRPRPASLGMGKDFAGIQGGKLVGLEQDQCSQQPSFKGQSYDKLPRPPCISVKISPKGIPDGHRREALKKLGLLKE", "length": 606 }, "evidence": [ { "id": "45239976", "url": "http://www.informatics.jax.org/homology/45239976", "database": "MGI" }, { "id": "Q499V8", "url": "https://omabrowser.org/oma/group/Q499V8/", "database": "OMA" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BW04-1", "protein_name": "Specifically androgen-regulated gene protein", "gene_name": "SARG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPERELWPAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFAGIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLKE", "length": 601 }, "evidence": [ { "id": "45239976", "url": "http://www.informatics.jax.org/homology/45239976", "database": "MGI" }, { "id": "Q499V8", "url": "https://omabrowser.org/oma/group/Q499V8/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q499V8", "url": "https://www.uniprot.org/uniprot/Q499V8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }