{ "uniprot_canonical_ac": "Q3UZ57-1", "uniprot_ac": "Q3UZ57", "uniprot_id": "AXDN1_MOUSE", "mass": { "chemical_mass": 126656.0, "monoisotopic_mass": 126656.0 }, "refseq": { "ac": "NP_001333896", "name": "axonemal dynein light chain domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333896" }, "gene_names": [ { "name": "Axdnd1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q3UZ57", "id": "Q3UZ57" }, { "name": "9430070O13Rik; Gm979", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333896", "id": "NP_001333896" }, { "name": "Axdnd1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333896", "id": "NP_001333896" } ], "protein_names": [ { "name": "Axonemal dynein light chain domain-containing protein 1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q3UZ57" }, { "name": "axonemal dynein light chain domain-containing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333896", "id": "NP_001333896" } ], "function": [ { "annotation": "Essential for spermiogenesis and male fertility probably by regulating the manchette dynamics, spermatid head shaping and sperm flagellum assembly.", "evidence": [ { "database": "UniProtKB", "id": "Q3UZ57", "url": "https://www.uniprot.org/uniprot/Q3UZ57#function" }, { "database": "PubMed", "id": "35386379", "url": "https://glygen.org/publication/PubMed/35386379" }, { "database": "PubMed", "id": "34759295", "url": "https://glygen.org/publication/PubMed/34759295" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UZ57", "url": "https://www.uniprot.org/uniprot/Q3UZ57" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Axdnd1", "url": "https://www.uniprot.org/uniprot/Q3UZ57", "locus": { "chromosome": "1", "start_pos": 156151079, "end_pos": 156248729, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000026601", "url": "https://www.ensembl.org/id/ENSMUSG00000026601" } ] } } ], "crossref": [ { "id": "ENSMUSG00000026601", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000026601", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12148", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12148", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "77352", "url": "https://www.ncbi.nlm.nih.gov/gene/77352", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:77352", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:77352", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1924602", "url": "http://www.informatics.jax.org/marker/MGI:1924602", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "KKECYEW", "url": "https://omabrowser.org/oma/group/KKECYEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2908507at2759", "url": "http://www.orthodb.org/?query=2908507at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23052:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23052:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10211", "url": "http://pfam.xfam.org/family/PF10211", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q3UZ57", "url": "http://purl.obolibrary.org/obo/PR_Q3UZ57", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001333896", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333896", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5RM11", "url": "https://www.uniprot.org/uniprot/A0A1D5RM11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5RM11-1", "url": "https://www.uniprot.org/uniprot/A0A1D5RM11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J3KMJ8", "url": "https://www.uniprot.org/uniprot/J3KMJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J3KMJ8-1", "url": "https://www.uniprot.org/uniprot/J3KMJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J3QMK9", "url": "https://www.uniprot.org/uniprot/J3QMK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J3QMK9-1", "url": "https://www.uniprot.org/uniprot/J3QMK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J3QNG8", "url": "https://www.uniprot.org/uniprot/J3QNG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J3QNG8-1", "url": "https://www.uniprot.org/uniprot/J3QNG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J3QPL7", "url": "https://www.uniprot.org/uniprot/J3QPL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J3QPL7-1", "url": "https://www.uniprot.org/uniprot/J3QPL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3UZ57", "url": "https://www.uniprot.org/uniprot/Q3UZ57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3UZ57-1", "url": "https://www.uniprot.org/uniprot/Q3UZ57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3UZ57-2", "url": "https://www.uniprot.org/uniprot/Q3UZ57-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLHKVSDTSLTSPSTSESKQAKLYVVKEAKGLPELKEKKSMVNHLKPLPPLQNDYRIPEEVLLSLNYAANAGPCPESLLPVKKPKAPKCALPRLVDHVWQHPIRRDKFKYLIDHPVSLTGAGRDISFLYDVKYVKGEAVEKKLCPPNKSTQSQSSAMVPHKEKTLADTLVPEEFHIVSNTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVVQLSNVMDTMLERAGIENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIREKYVQMLDHIAQQMIEFYKDLVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYELALKVIERNRVILAKKLYLSEKGWNKYAKHFIIMLSTKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKEKSEIVKAGIIKWQEFFNNNLGKDVIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKSMDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENFLDYSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGAALLEHICEMIQQWLLKLGNEITNGQIELLRHMDEMHIAMIQWMVNLLTIMLPDFTDQDILPKREESSLETPEEHEIGIAELEINAIALVKRLARYSSYLHSCCIGMVRAMALSRAAHLQKNPAKDRQDLERMNRECYDWISTCSHLISDIKGRKIRLLSYEEAEKLLGEEEASKLYFDPEKPPIDDDTDDEIDFKKPKFQEKEAPLPAAAEAEAIEATEAAGAATAEATGAAETATAEATGPATAEAAGAAGAATAEATEAAGAATAEATGAAGAKVTTEQGPSPSTNEKTIRYIKKDENIHCKPLFEEGIFFSWREPPSQGVMEPKYLEIMNVIEHMQRKLTEMDTRARKAEERFDEVNEQLHHSLIRNRNLERELEELVKTTMMGSQVKTENAKENQEDRGGKDDDEHQQTQTPPTSAKKEAQPTNSSEAPEDQNTPEPKPN", "length": 1111, "header": "sp|Q3UZ57-1|AXDN1_MOUSE Isoform 1 of Axonemal dynein light chain domain-containing protein 1 OS=Mus musculus OX=10090 GN=Axdnd1 PE=1 SV=2 CANONICAL=Q3UZ57-1" }, "isoforms": [ { "isoform_ac": "A0A1D5RM11-1", "url": "", "sequence": { "sequence": "MEASKLYFDPEKPPIDDDTDDEIDFKKPKFQEKEAPLPAAAEAEAIEATEAAGAATAEATGAAETATAEATGPATAEAAGAAGAATAEATEAAGAATAEATGAAGAKVTTEQGPSPSTNEKTIRYIKKDENIHCKPLFEEGIFFSWREPPSQGVMEPKYLEIMNVIEHMQRKLTEMDTRARKAEERFDEVNEQLHHSLIRNRNLERELEELVKTTMMGSQVKTENAKENQEDRGGKDDDEHQQTQTPPTSAKKEAQPTNSSEAPEDQNTPEPKPN", "length": 275, "header": "tr|A0A1D5RM11-1|A0A1D5RM11_MOUSE Computationally mapped isoform of Axonemal dynein light chain domain containing 1 OS=Mus musculus OX=10090 GN=Axdnd1 PE=1 SV=1 CANONICAL=Q3UZ57-1" }, "locus": { "chromosome": "1", "start_pos": 156168333, "end_pos": 156158216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000212747.2", "url": "https://www.ensembl.org/id/ENSMUST00000212747.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000148583.2", "url": "https://www.ensembl.org/id/ENSMUSP00000148583.2" } ] } }, { "isoform_ac": "J3KMJ8-1", "url": "", "sequence": { "sequence": "LNYAANAGPCPESLLPVKKPKAPKCALPRLVDHVWQHPIRRDKFKYLIDHPVSLTGAGRDISFLYDVKYVKGEAVEKKLCPPNKSTQSQSSAMVPHKEKTLADTLVPEEFHIVSNTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVVQLSNVMDTMLERAGIENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIREKYVQMLDHIAQQMIEFYKDLVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYELALKVIERNRVILAKKLYLSEKGWNKYAKHFIIMLSTKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKEKSEIVKAGIIKWQEFFNNNLGKDVIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKSMDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENFLDYSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGAALLEHICEMIQQWLLKLGNEITNGQIELLRHMDEMHIAMIQWMVNLLTIMLPDFTDQDILPKREESSLETPEEHEIGIAELEINAIALVKRLARYSSYLHSCCIGMVRAMALSRAAHLQKNPAKDRQDLERMNGPSPSTNEKTIRYIKKDENIHCKPLFEEGIFFSWREPPSQGVMEPKYLEIMNVIEHMQRKLTEMDTRARKAEERFDEVNEQLHHSLIRNRNLERELEELVKTTMMGSQVKTENAKENQEDRGGKDDDEHQQTQTPPTSAKKGHCI", "length": 880, "header": "tr|J3KMJ8-1|J3KMJ8_MOUSE Computationally mapped isoform of Axonemal dynein light chain domain containing 1 OS=Mus musculus OX=10090 GN=Axdnd1 PE=1 SV=1 CANONICAL=Q3UZ57-1" }, "locus": { "chromosome": "1", "start_pos": 156246880, "end_pos": 156151316, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000177824.8", "url": "https://www.ensembl.org/id/ENSMUST00000177824.8" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000135900.2", "url": "https://www.ensembl.org/id/ENSMUSP00000135900.2" } ] } }, { "isoform_ac": "J3QMK9-1", "url": "", "sequence": { "sequence": "MSLHKVSDTSLTSPSTSESKQAKLYVVKEAKGLPELKEKKSMVNHLKP", "length": 48, "header": "tr|J3QMK9-1|AXDN1_MOUSE Computationally mapped isoform of Axonemal dynein light chain domain-containing protein 1 OS=Mus musculus OX=10090 GN=Axdnd1 PE=1 SV=1 CANONICAL=Q3UZ57-1" }, "locus": { "chromosome": "1", "start_pos": 156247998, "end_pos": 156246932, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000179744.2", "url": "https://www.ensembl.org/id/ENSMUST00000179744.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000137094.2", "url": "https://www.ensembl.org/id/ENSMUSP00000137094.2" } ] } }, { "isoform_ac": "J3QNG8-1", "url": "", "sequence": { "sequence": "XTTLLTDSENRLLLFPSMKPNKRVEVVQLSNVMDTMLERAGIENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIRYLLIFCVRAAREEPGFPPITSPPVLCLSHREKYVQMLDHIAQQMIEFYKDLVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYELALKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKEKSEIVKAGIIKWQEFFNNNLGKDVIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKSMDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENFLDYSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGA", "length": 471, "header": "tr|J3QNG8-1|J3QNG8_MOUSE Computationally mapped isoform of Axonemal dynein light chain domain containing 1 OS=Mus musculus OX=10090 GN=Axdnd1 PE=1 SV=1 CANONICAL=Q3UZ57-1" }, "locus": { "chromosome": "1", "start_pos": 156226112, "end_pos": 156193183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000180173.2", "url": "https://www.ensembl.org/id/ENSMUST00000180173.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000136744.2", "url": "https://www.ensembl.org/id/ENSMUSP00000136744.2" } ] } }, { "isoform_ac": "J3QPL7-1", "url": "", "sequence": { "sequence": "MSLHKVSDTSLTSPSTSESKQAKLYVVKEAKGLPELKEKKSMVNHLKPLPPLQNDYRIPEEVLLSLNYAANAGPCPESLLPVKKPKAPKCALPRLVDHVWQHPIRRDKFKYLIDHPVSLTGAGRDISFLYDVKYVKGEAVEKKLCPPNKSTQSQSSAMVPHKEKTLADTLVPEEFHIVSNTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVVQLSNVMDTMLERAGIENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIREKYVQMLDHIAQQMIEFYKDLVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYELALKVIERNRVILAKKLYLSEKGWNKYAKHFIIMLSTKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKEKSEIVKAGIIKWQEFFNNNLGKDVIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKSMDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENFLDYSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGAALLEHICEMIQQWLLKLGNEITNGQIELLRHMDEMHIAMIQWMVNLLTIMLPDFTDQDILPKREESSLETPEEHEIGIAELEINAIALVKRLARYSSYLHSCCIGMVRAMALSRAAHLQKNPAKDRQDLERMNRECYDWISTCSHLISDIKGRKIRLLSYEEAEKLLGEEGPSPSTNEKTIRYIKKDENIHCKPLFEEGIFFSWREPPSQGVMEPKYLEIMNVIEHMQRKLTEMDTRARKAEERFDEVNEQLHHSLIRNRNLERELEELVKTTMMGSQVKTENAKENQEDRGGKDDDEHQQTQTPPTSAKKGHCI", "length": 982, "header": "tr|J3QPL7-1|J3QPL7_MOUSE Computationally mapped isoform of Axonemal dynein light chain domain containing 1 OS=Mus musculus OX=10090 GN=Axdnd1 PE=1 SV=1 CANONICAL=Q3UZ57-1" }, "locus": { "chromosome": "1", "start_pos": 156247998, "end_pos": 156151316, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000178036.8", "url": "https://www.ensembl.org/id/ENSMUST00000178036.8" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000137354.2", "url": "https://www.ensembl.org/id/ENSMUSP00000137354.2" } ] } }, { "isoform_ac": "Q3UZ57-1", "url": "", "sequence": { "sequence": "MSLHKVSDTSLTSPSTSESKQAKLYVVKEAKGLPELKEKKSMVNHLKPLPPLQNDYRIPEEVLLSLNYAANAGPCPESLLPVKKPKAPKCALPRLVDHVWQHPIRRDKFKYLIDHPVSLTGAGRDISFLYDVKYVKGEAVEKKLCPPNKSTQSQSSAMVPHKEKTLADTLVPEEFHIVSNTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVVQLSNVMDTMLERAGIENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIREKYVQMLDHIAQQMIEFYKDLVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYELALKVIERNRVILAKKLYLSEKGWNKYAKHFIIMLSTKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKEKSEIVKAGIIKWQEFFNNNLGKDVIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKSMDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENFLDYSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGAALLEHICEMIQQWLLKLGNEITNGQIELLRHMDEMHIAMIQWMVNLLTIMLPDFTDQDILPKREESSLETPEEHEIGIAELEINAIALVKRLARYSSYLHSCCIGMVRAMALSRAAHLQKNPAKDRQDLERMNRECYDWISTCSHLISDIKGRKIRLLSYEEAEKLLGEEEASKLYFDPEKPPIDDDTDDEIDFKKPKFQEKEAPLPAAAEAEAIEATEAAGAATAEATGAAETATAEATGPATAEAAGAAGAATAEATEAAGAATAEATGAAGAKVTTEQGPSPSTNEKTIRYIKKDENIHCKPLFEEGIFFSWREPPSQGVMEPKYLEIMNVIEHMQRKLTEMDTRARKAEERFDEVNEQLHHSLIRNRNLERELEELVKTTMMGSQVKTENAKENQEDRGGKDDDEHQQTQTPPTSAKKEAQPTNSSEAPEDQNTPEPKPN", "length": 1111, "header": "sp|Q3UZ57-1|AXDN1_MOUSE Isoform 1 of Axonemal dynein light chain domain-containing protein 1 OS=Mus musculus OX=10090 GN=Axdnd1 PE=1 SV=2 CANONICAL=Q3UZ57-1" }, "locus": {} }, { "isoform_ac": "Q3UZ57-2", "url": "", "sequence": { "sequence": "MKPNKRVEVVQLSNVMDTMLERAGIENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCADRGELLSKIREKYVQMLDHIAQQMIEFYKDLVTQRMMDQRILQELYNFKNVIEELTRELCLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMTERDIWSSATYELALKDTGDLGMVEKLTEKWKKLVNKFKQDVERTEESTKEKSEIVKAGIIKWQEFFNNNLGKDVIIPSKRSPFAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKSMDGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENFLDYSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGA", "length": 424, "header": "sp|Q3UZ57-2|AXDN1_MOUSE Isoform 2 of Axonemal dynein light chain domain-containing protein 1 OS=Mus musculus OX=10090 GN=Axdnd1 PE=1 SV=2 CANONICAL=Q3UZ57-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "AXDND1, a novel testis-enriched gene, is required for spermiogenesis and male fertility.", "journal": "Cell. Death. Discov.", "date": "2021", "authors": "Ma Qian, Cao Congcong, Zhuang Changshui, Luo Xiaomin, Li Xiaofeng, Wan Huijuan, Ye Jing, Chen Fangfang, Cui Lina, Zhang Yan, Wen Yujiao, Yuan Shuiqiao, Gui Yaoting", "evidence": [ { "database": "UniProtKB", "id": "Q3UZ57", "url": "https://www.uniprot.org/uniprot/Q3UZ57" } ], "reference": [ { "type": "PubMed", "id": "34759295", "url": "https://glygen.org/publication/PubMed/34759295" } ] }, { "title": "Loss of Axdnd1 causes sterility due to impaired spermatid differentiation in mice.", "journal": "Reprod. Med. Biol.", "date": "2022", "authors": "Kobayashi T., Hara K., Yasui A., Kanno S.I., Nagasawa K., Osada M., Matsuyama M., Tanemura K., Harima R., Hiradate Y., Yanai R.", "evidence": [ { "database": "UniProtKB", "id": "Q3UZ57", "url": "https://www.uniprot.org/uniprot/Q3UZ57" } ], "reference": [ { "type": "PubMed", "id": "35386379", "url": "https://glygen.org/publication/PubMed/35386379" } ] } ], "pathway": [ { "id": "mmu:77352", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:77352", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5T1B0-1", "protein_name": "Axonemal dynein light chain domain-containing protein 1", "gene_name": "AXDND1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLPKTPSTPLNSTSTSESKKLKVSVAKEGTRGLPELKEKKNMVDRSKLLPTSLQNEFIPKEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSLTGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHIVSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGVENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKKGH", "length": 1012 }, "evidence": [ { "id": "45228468", "url": "http://www.informatics.jax.org/homology/45228468", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1095, "end_pos": 1097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }