{
    "uniprot_canonical_ac": "Q2TA51-1",
    "uniprot_ac": "Q2TA51",
    "uniprot_id": "KRA55_MOUSE",
    "mass": {
        "chemical_mass": 23063.0,
        "monoisotopic_mass": 23063.0
    },
    "refseq": {
        "ac": "NP_001032911",
        "name": "keratin-associated protein 5-5",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032911"
    },
    "gene_names": [
        {
            "name": "Krtap5-5",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q2TA51",
            "id": "Q2TA51"
        },
        {
            "name": "A030001H12Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032911",
            "id": "NP_001032911"
        },
        {
            "name": "Krtap5-5",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032911",
            "id": "NP_001032911"
        }
    ],
    "protein_names": [
        {
            "name": "Keratin-associated protein 5-5",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q2TA51"
        },
        {
            "name": "keratin-associated protein 5-5",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032911",
            "id": "NP_001032911"
        }
    ],
    "function": [
        {
            "annotation": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q2TA51",
                    "url": "https://www.uniprot.org/uniprot/Q2TA51#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q2TA51",
                    "url": "https://www.uniprot.org/uniprot/Q2TA51"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Krtap5-5",
            "url": "https://www.uniprot.org/uniprot/Q2TA51",
            "locus": {
                "chromosome": "7",
                "start_pos": 141782532,
                "end_pos": 141783708,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000073785",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000073785"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000073785",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000073785",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "114666",
            "url": "https://www.ncbi.nlm.nih.gov/gene/114666",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR002494",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002494",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:114666",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:114666",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "2149673",
            "url": "http://www.informatics.jax.org/marker/MGI:2149673",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "DSCCKPC",
            "url": "https://omabrowser.org/oma/group/DSCCKPC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13885",
            "url": "http://pfam.xfam.org/family/PF13885",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q2TA51",
            "url": "http://purl.obolibrary.org/obo/PR_Q2TA51",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-6805567",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6805567",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001032911",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032911",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q2TA51",
            "url": "https://www.uniprot.org/uniprot/Q2TA51",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q2TA51-1",
            "url": "https://www.uniprot.org/uniprot/Q2TA51-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MTCCGCSGGCGSSCGGCGCSGGCGSSCGGCGSSCCCKPVCCCKPVCCCVPACSCSSCGGCKGGCGSCGGCKGSCGSCGGCKGGCGSCGGCGSCGGCKPSCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCAPVCCQCKI",
        "length": 241,
        "header": "sp|Q2TA51-1|KRA55_MOUSE Isoform 1 of Keratin-associated protein 5-5  OS=Mus musculus OX=10090 GN=Krtap5-5 PE=2 SV=1 CANONICAL=Q2TA51-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q2TA51-1",
            "url": "",
            "sequence": {
                "sequence": "MTCCGCSGGCGSSCGGCGCSGGCGSSCGGCGSSCCCKPVCCCKPVCCCVPACSCSSCGGCKGGCGSCGGCKGSCGSCGGCKGGCGSCGGCGSCGGCKPSCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCAPVCCQCKI",
                "length": 241,
                "header": "sp|Q2TA51-1|KRA55_MOUSE Isoform 1 of Keratin-associated protein 5-5  OS=Mus musculus OX=10090 GN=Krtap5-5 PE=2 SV=1 CANONICAL=Q2TA51-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 141783648,
                "end_pos": 141782926,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000097942",
                        "url": "https://www.ensembl.org/id/ENSMUST00000097942"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000095555",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000095555"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:114666",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:114666",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-6805567",
            "name": "Keratinization",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6805567",
            "resource": "Reactome",
            "description": "Keratinization"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q701N2-1",
            "protein_name": "Keratin-associated protein 5-5",
            "gene_name": "KRTAP5-5",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MGCCGCSGGCGSGCGGRGSGCGGCGSGCGGCGSGCGGCGSGCGGCGGCGSGCAGCGGCGSGCCVPVCCCKPMCCCVPACSCSSCGKGGCGSCGGSKRGCVSCGVSKGACGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSYGCSQSSCCKPCCCSSGCGSSCCQSSCCKPYCCQSSCCKPYCCQSSCCKPCSCFSGCGSSCCQSSCYKPCCCQSSCCVPVCCQCKI",
                "length": 237
            },
            "evidence": [
                {
                    "id": "45241852",
                    "url": "http://www.informatics.jax.org/homology/45241852",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "hematopoietic progenitor cell differentiation",
                        "id": "GO:0002244",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2TA51",
                                "url": "https://www.uniprot.org/uniprot/Q2TA51"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "keratin filament",
                        "id": "GO:0045095",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2TA51",
                                "url": "https://www.uniprot.org/uniprot/Q2TA51"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
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}
