{
    "uniprot_canonical_ac": "Q2PWT8-1",
    "uniprot_ac": "Q2PWT8",
    "uniprot_id": "AP4M1_RAT",
    "mass": {
        "chemical_mass": 49853.0,
        "monoisotopic_mass": 49853.0
    },
    "refseq": {
        "ac": "NP_001033066",
        "name": "AP-4 complex subunit mu-1 isoform 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033066"
    },
    "gene_names": [
        {
            "name": "Ap4m1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q2PWT8",
            "id": "Q2PWT8"
        },
        {
            "name": "Ap4m1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033066",
            "id": "NP_001033066"
        }
    ],
    "protein_names": [
        {
            "name": "AP-4 complex subunit mu-1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q2PWT8"
        },
        {
            "name": "AP-4 adaptor complex mu subunit",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q2PWT8"
        },
        {
            "name": "AP-4 complex subunit mu-1 isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033066",
            "id": "NP_001033066"
        },
        {
            "name": "AP-4 complex subunit mu-1; mu4; mu-ARP2; mu4-adaptin; mu subunit of AP-4; mu-adaptin-related protein 2; AP-4 adapter complex mu subunit; adaptor-related protein complex 4, mu 1 subunit; adapter-related protein complex 4 mu-1 subunit; adaptor-related protein complex AP-4, mu 1; adapter-related protein complex 4 subunit mu-1; AP-4 adaptor complex mu subunit",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033066",
            "id": "NP_001033066"
        },
        {
            "name": "Adaptor-related protein complex 4 subunit mu-1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q2PWT8"
        },
        {
            "name": "Mu subunit of AP-4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q2PWT8"
        },
        {
            "name": "Mu-adaptin-related protein 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q2PWT8"
        },
        {
            "name": "Mu4-adaptin",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q2PWT8"
        },
        {
            "name": "mu-ARP2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q2PWT8"
        },
        {
            "name": "mu4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q2PWT8"
        }
    ],
    "function": [
        {
            "annotation": "AP4M1 is not only down-regulated at both the mRNA and protein levels, but also redistributed from dendrites to axons in oxygen-glucose deprived hippocampal neurons.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001033066",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033066"
                },
                {
                    "database": "PubMed",
                    "id": "24486887",
                    "url": "https://glygen.org/publication/PubMed/24486887"
                }
            ]
        },
        {
            "annotation": "Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos (By similarity). The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal (PubMed:14572453).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q2PWT8",
                    "url": "https://www.uniprot.org/uniprot/Q2PWT8#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "O00189",
                    "url": "https://www.uniprot.org/uniprot/O00189#function"
                },
                {
                    "database": "PubMed",
                    "id": "14572453",
                    "url": "https://glygen.org/publication/PubMed/14572453"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A8I6B231",
                    "url": "https://www.uniprot.org/uniprot/A0A8I6B231#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "PIRNR005992",
                    "url": "https://www.uniprot.org/uniprot/PIRNR005992#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0110802",
            "recommended_name": {
                "id": "DOID:0110802",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0110802",
                "name": "hereditary spastic paraplegia 50",
                "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the AP4M1 gene on chromosome 7q22.1."
            },
            "synonyms": [
                {
                    "id": "DOID:0110802",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110802",
                    "name": "SPG50",
                    "description": ""
                },
                {
                    "id": "DOID:0110802",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110802",
                    "name": "autosomal recessive spastic paraplegia 50",
                    "description": ""
                },
                {
                    "id": "DOID:0110802",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110802",
                    "name": "AP-4 deficiency syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0110802",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110802",
                    "name": "AP-4-Associated Hereditary Spastic Paraplegia",
                    "description": ""
                },
                {
                    "id": "DOID:0110802",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110802",
                    "name": "adaptor protein complex 4 deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0013048",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013048",
                    "name": "hereditary spastic paraplegia 50",
                    "description": "Any hereditary spastic paraplegia in which the cause of the disease is a mutation in the AP4M1 gene."
                },
                {
                    "id": "MONDO:0013048",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013048",
                    "name": "AP4M1 hereditary spastic paraplegia",
                    "description": ""
                },
                {
                    "id": "MONDO:0013048",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013048",
                    "name": "SPG50",
                    "description": ""
                },
                {
                    "id": "MONDO:0013048",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013048",
                    "name": "autosomal recessive spastic paraplegia 50",
                    "description": ""
                },
                {
                    "id": "MONDO:0013048",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013048",
                    "name": "hereditary spastic paraplegia caused by mutation in AP4M1",
                    "description": ""
                },
                {
                    "id": "MONDO:0013048",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013048",
                    "name": "hereditary spastic paraplegia type 50",
                    "description": ""
                },
                {
                    "id": "MONDO:0013048",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013048",
                    "name": "cerebral palsy, spastic quadriplegic, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0013048",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013048",
                    "name": "cerebral palsy, spastic quadriplegic, 3, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0013048",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013048",
                    "name": "spastic paraplegia 50, autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MIM:612936",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/612936",
                    "name": "Spastic paraplegia 50, autosomal recessive",
                    "description": "Spastic paraplegia 50, autosomal recessive"
                }
            ],
            "evidence": [
                {
                    "id": "0110802",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110802"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q2PWT8",
                    "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Ap4m1",
            "url": "https://www.uniprot.org/uniprot/Q2PWT8",
            "locus": {
                "chromosome": "12",
                "start_pos": 17058026,
                "end_pos": 17049777,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000001353",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000001353"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000001353",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000001353",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd09253",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09253",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd14838",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14838",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "304344",
            "url": "https://www.ncbi.nlm.nih.gov/gene/304344",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001392",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001392",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011012",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018240",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018240",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR022775",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR028565",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028565",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036168",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036168",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:304344",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304344",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "DYGYIQN",
            "url": "https://omabrowser.org/oma/group/DYGYIQN/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5353102at2759",
            "url": "http://www.orthodb.org/?query=5353102at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10529",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10529",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10529:SF270",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10529:SF270",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00928",
            "url": "http://pfam.xfam.org/family/PF00928",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01217",
            "url": "http://pfam.xfam.org/family/PF01217",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q2PWT8",
            "url": "http://purl.obolibrary.org/obo/PR_Q2PWT8",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-RNO-432720",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-432720",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001033066",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033066",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1310233",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310233",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8I6B231",
            "url": "https://www.uniprot.org/uniprot/A0A8I6B231",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6B231-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6B231-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q2PWT8",
            "url": "https://www.uniprot.org/uniprot/Q2PWT8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q2PWT8-1",
            "url": "https://www.uniprot.org/uniprot/Q2PWT8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGGESPVVMYHDDRHFIHIRHSGLYLVATTSENVSPFSLLELLSRLATLLGDYCGSLNEGTISRNVALVYELLDEVLDYGYVQTTSTDMLRNFIQTEAAVSKPFSLFDLSSVGLFGAETQQNRVAPSSAASRPVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSSSEICIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILHLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDQGSGRLQVYLKLRCDLPPKSQALNIHLHLPLPRGVVSLSQELSSPDQKAELGEGALHWDLPRVQGGSQLSGLFQMDVPGLQGPPSRGPSPSAPPLGLGPASLSFELPRHTCSGLQVRFLRLSFSACGNANPHKWVRHLSHSNAYVIRI",
        "length": 453,
        "header": "sp|Q2PWT8-1|AP4M1_RAT Isoform 1 of AP-4 complex subunit mu-1  OS=Rattus norvegicus OX=10116 GN=Ap4m1 PE=1 SV=1 CANONICAL=Q2PWT8-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I6B231-1",
            "url": "",
            "sequence": {
                "sequence": "MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGGESPVVMYHDDRHFIHIRHSGLYLVATTSENVSPFSLLELLSRLATLLGDYCGSLNEGTISRNVALVYELLDEVLDYGYVQTTSTDMLRNFIQTEAAVSKPFSLFDLSSVGLFGAETQQNRVAPSSAASRPVLSSRSDQVREGSVGPDLMIFLGSLLKVDVQGEIRLKSFLPSSSEICIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILHLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDQGSGRLQVYLKLRCDLPPKSQALNIHLHLPLPRGVVSLSQELSSPDQKAELGEGALHWDLPRVQGGSQLSGLFQMDVPGLQGPPSRGPSPSAPPLGLGPASLSFELPRHTCSGLQVRFLRLSFSACGNANPHKWVRHLSHSNAYVIRI",
                "length": 446,
                "header": "tr|A0A8I6B231-1|A0A8I6B231_RAT Computationally mapped isoform of AP-4 complex subunit mu-1  OS=Rattus norvegicus OX=10116 GN=Ap4m1 PE=3 SV=1 CANONICAL=Q2PWT8-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 17055734,
                "end_pos": 17049844,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000111429.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000111429.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000095152.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000095152.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q2PWT8-1",
            "url": "",
            "sequence": {
                "sequence": "MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGGESPVVMYHDDRHFIHIRHSGLYLVATTSENVSPFSLLELLSRLATLLGDYCGSLNEGTISRNVALVYELLDEVLDYGYVQTTSTDMLRNFIQTEAAVSKPFSLFDLSSVGLFGAETQQNRVAPSSAASRPVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSSSEICIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILHLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDQGSGRLQVYLKLRCDLPPKSQALNIHLHLPLPRGVVSLSQELSSPDQKAELGEGALHWDLPRVQGGSQLSGLFQMDVPGLQGPPSRGPSPSAPPLGLGPASLSFELPRHTCSGLQVRFLRLSFSACGNANPHKWVRHLSHSNAYVIRI",
                "length": 453,
                "header": "sp|Q2PWT8-1|AP4M1_RAT Isoform 1 of AP-4 complex subunit mu-1  OS=Rattus norvegicus OX=10116 GN=Ap4m1 PE=1 SV=1 CANONICAL=Q2PWT8-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 17055734,
                "end_pos": 17049844,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000001827",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000001827"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000001827",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000001827"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Adaptor protein complex-4 (AP-4) is expressed in the central nervous system neurons and interacts with glutamate receptor delta2.",
            "journal": "Mol. Cell. Neurosci.",
            "date": "2003",
            "authors": "Yap CC, Murate M, Kishigami S, Muto Y, Kishida H, Hashikawa T, Yano R",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q2PWT8",
                    "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "14572453",
                    "url": "https://glygen.org/publication/PubMed/14572453"
                }
            ]
        },
        {
            "title": "AP4M1 is abnormally expressed in oxygen-glucose deprived hippocampal neurons.",
            "journal": "Neuroscience letters",
            "date": "2014",
            "authors": "Zhang J, Cheng XY, Sheng GY",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001033066",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033066"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "24486887",
                    "url": "https://glygen.org/publication/PubMed/24486887"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:304344",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304344",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-432720",
            "name": "Lysosome Vesicle Biogenesis",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-432720",
            "resource": "Reactome",
            "description": "Lysosome Vesicle Biogenesis"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "O00189-1",
            "protein_name": "AP-4 complex subunit mu-1",
            "gene_name": "AP4M1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGRHFIHIRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIRI",
                "length": 453
            },
            "evidence": [
                {
                    "id": "45232918",
                    "url": "http://www.informatics.jax.org/homology/45232918",
                    "database": "MGI"
                },
                {
                    "id": "Q2PWT8",
                    "url": "https://omabrowser.org/oma/group/Q2PWT8/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9JKC7-1",
            "protein_name": "AP-4 complex subunit mu-1",
            "gene_name": "Ap4m1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGGESPVVMYHGDRHFIHIRHSGLYLVATTLENVSPFSLLELLSRLATLLGDYCGSLNEGTISRNVALVYELLDEVLDYGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQNKVAPSSAASRPVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEICIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDQGSGRLQVYLKLRCDLPPKSQALNIHLHLPLPRGVISLSQELSSPDQKAELGEGALHWDLPRVQGGSQLSGLFQMDVPGLQGLPNHGPSPLGLGPASLSFELPRHTCSGLQVRFLRLSFSACGNANPHKWVRHLSHSNAYVIRI",
                "length": 449
            },
            "evidence": [
                {
                    "id": "45232918",
                    "url": "http://www.informatics.jax.org/homology/45232918",
                    "database": "MGI"
                },
                {
                    "id": "Q2PWT8",
                    "url": "https://omabrowser.org/oma/group/Q2PWT8/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 9,
                "go_terms": [
                    {
                        "name": "autophagosome assembly",
                        "id": "GO:0000045",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "intracellular protein transport",
                        "id": "GO:0006886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein targeting",
                        "id": "GO:0006605",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein localization",
                        "id": "GO:0008104",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein targeting to lysosome",
                        "id": "GO:0006622",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006622",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi to lysosome transport",
                        "id": "GO:0090160",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090160",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi to endosome transport",
                        "id": "GO:0006895",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein localization to basolateral plasma membrane",
                        "id": "GO:1903361",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903361",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "vesicle-mediated transport",
                        "id": "GO:0016192",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 7,
                "go_terms": [
                    {
                        "name": "early endosome",
                        "id": "GO:0005769",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasmic vesicle",
                        "id": "GO:0031410",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "trans-Golgi network",
                        "id": "GO:0005802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "clathrin adaptor complex",
                        "id": "GO:0030131",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030131",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "AP-4 adaptor complex",
                        "id": "GO:0030124",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030124",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi apparatus",
                        "id": "GO:0005794",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "protein domain specific binding",
                        "id": "GO:0019904",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q2PWT8",
                                "url": "https://www.uniprot.org/uniprot/Q2PWT8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 202,
            "end_pos": 204,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 73,
            "end_pos": 75,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 2
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}