{ "uniprot_canonical_ac": "Q24563-1", "uniprot_ac": "Q24563", "uniprot_id": "DOPR2_DROME", "mass": { "chemical_mass": 59505.0, "monoisotopic_mass": 59505.0 }, "refseq": { "ac": "NP_524548", "name": "dopamine 1-like receptor 2, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524548" }, "gene_names": [ { "name": "Dop1R2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "CG18741; CG7569; D1R2; D2R; damb; Damb; DAMB; Dar2; DDR2; DmDOP2; Dmel\\CG18741; DopD1; DopR; dopr2; DopR2; DOPR2; DopR99B; DOPR99B; DopRII; DR2; K13sc", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263072", "id": "NP_001263072" }, { "name": "CG18741", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "CG7569", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "D2R", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DAMB", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DDR2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DOPR2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DOPR99B", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DR2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "Damb", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "Dar2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DmDOP2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "Dmel\\CG18741", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "Dmel_CG18741", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "Dop1R2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263072", "id": "NP_001263072" }, { "name": "DopD1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DopR2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DopR99B", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DopRII", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "DopR", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "K13sc", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "damb", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" }, { "name": "dopr2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q24563", "id": "Q24563" } ], "protein_names": [ { "name": "Dopamine receptor 2", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q24563" }, { "name": "CG18741-PB; Dop1R2-PB; dopamine receptor in mushroom body; DAMB DA receptor; D[[2]]-like receptor; dopamine receptor 2; damb; K13sc; dopamine-2 receptor; dopamine receptor in mushroom bodies", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524548", "id": "NP_524548" }, { "name": "CG18741-PC; Dop1R2-PC; dopamine receptor in mushroom body; DAMB DA receptor; D[[2]]-like receptor; dopamine receptor 2; damb; K13sc; dopamine-2 receptor; dopamine receptor in mushroom bodies", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263072", "id": "NP_001263072" }, { "name": "Dopamine 1-like receptor 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q24563" }, { "name": "dopamine 1-like receptor 2, isoform B", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524548", "id": "NP_524548" }, { "name": "dopamine 1-like receptor 2, isoform C", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263072", "id": "NP_001263072" } ], "function": [ { "annotation": "Receptor for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Also capable of generating a calcium signal. In terms of antagonist responses, would be classed with the D1-like dopamine receptor group. This receptor is an attractive candidate for initiating biochemical cascades underlying olfactory learning.", "evidence": [ { "database": "UniProtKB", "id": "Q24563", "url": "https://www.uniprot.org/uniprot/Q24563#function" }, { "database": "PubMed", "id": "8656286", "url": "https://glygen.org/publication/PubMed/8656286" }, { "database": "PubMed", "id": "8663989", "url": "https://glygen.org/publication/PubMed/8663989" } ] } ], "disease": [ { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "evidence": [ { "id": "10652", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "evidence": [ { "id": "10763", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] }, { "disease_id": "DOID:11612", "recommended_name": { "id": "DOID:11612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11612", "name": "polycystic ovary syndrome", "description": "An ovarian dysfunction that is characterized by hyperandrogenism, polycystic ovaries, hirsutism, oligomenorrhea or amenorrhea, anovulation and excessive body weight." }, "synonyms": [ { "id": "DOID:11612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11612", "name": "Multicystic ovaries", "description": "" }, { "id": "DOID:11612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11612", "name": "PCOS", "description": "" }, { "id": "DOID:11612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11612", "name": "Polycystic Ovarian disease", "description": "" }, { "id": "DOID:11612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11612", "name": "Polycystic ovaries", "description": "" }, { "id": "DOID:11612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11612", "name": "Stein-Leventhal synd.", "description": "" }, { "id": "DOID:11612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11612", "name": "Stein-Leventhal syndrome", "description": "" }, { "id": "DOID:11612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11612", "name": "polycystic ovary", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "polycystic ovary syndrome", "description": "A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity." }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "PCOS", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "Stein-Leventhal synd.", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "Stein-Leventhal syndrome", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "multicystic ovaries", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "polycystic ovarian disease", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "polycystic ovaries", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "polycystic ovary", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "polycystic ovary syndrome", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "PCOS1", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "polycystic ovary syndrome 1", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "PCO1", "description": "" }, { "id": "MONDO:0008487", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008487", "name": "hyperandrogenemia", "description": "" } ], "evidence": [ { "id": "11612", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:11612" } ] }, { "disease_id": "DOID:13948", "recommended_name": { "id": "DOID:13948", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:13948", "name": "bladder neck obstruction", "description": "" }, "synonyms": [ { "id": "DOID:13948", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:13948", "name": "Obstruction of bladder neck or vesicourethral orifice", "description": "" } ], "evidence": [ { "id": "13948", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:13948" } ] }, { "disease_id": "DOID:1574", "recommended_name": { "id": "DOID:1574", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences." }, "synonyms": [ { "id": "DOID:1574", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1574", "name": "Ethanol abuse", "description": "" }, { "id": "DOID:1574", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1574", "name": "alcohol abuse", "description": "" } ], "evidence": [ { "id": "1574", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q24563", "url": "https://www.uniprot.org/uniprot/Q24563" } ], "common_name": "Fruit fly" } ], "gene": [ { "name": "Dop1R2", "url": "https://www.uniprot.org/uniprot/Q24563", "locus": { "chromosome": "3R", "start_pos": 29630304, "end_pos": 29659984, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0266137", "url": "https://www.ensembl.org/id/FBgn0266137" } ] } } ], "crossref": [ { "id": "FBgn0266137", "url": "https://bgee.org/?page=gene&gene_id=FBgn0266137", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15067", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15067", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0266137", "url": "https://flybase.org/reports/FBgn0266137", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "43484", "url": "https://www.ncbi.nlm.nih.gov/gene/43484", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG18741", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG18741", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DRTLMXR", "url": "https://omabrowser.org/oma/group/DRTLMXR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "4073525at2759", "url": "http://www.orthodb.org/?query=4073525at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248:SF185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248:SF185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "http://pfam.xfam.org/family/PF00001", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q24563", "url": "http://purl.obolibrary.org/obo/PR_Q24563", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_524548", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0B4KI18", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KI18-1", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q24563", "url": "https://www.uniprot.org/uniprot/Q24563", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q24563-1", "url": "https://www.uniprot.org/uniprot/Q24563-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q24563-2", "url": "https://www.uniprot.org/uniprot/Q24563-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDDNGSSPEVEGAEGAGAPLLALLRVDGLNQTQTRSPSPSFFGSYNISEDVYFYFNGLPTSTELVLNATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARDGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLMASGELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCCPRKIRRKYQPTMRSKSQRFATRRCYSTCSLHGIQHVRHNSCEQTYI", "length": 539, "header": "sp|Q24563-1|DOPR2_DROME Isoform 1 of Dopamine receptor 2 OS=Drosophila melanogaster OX=7227 GN=Dop1R2 PE=2 SV=1 CANONICAL=Q24563-1" }, "isoforms": [ { "isoform_ac": "A0A0B4KI18-1", "url": "", "sequence": { "sequence": "MVDDNGSSPEVEGAEGAGAPLLALLRVDGLNQTQTRSPSPSFFGSYNISEDVYFYFNGLPTSTELVLNATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARDGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLMASGELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCCPRKIRRKYQPTMRSKSQCHVAAAMVAASTSFGYHSVNQIDRTLMXRQLSSCSTCSGGSNCGGSRSAHHQHHSSGTATPSSSQRSCTRCQSFHRHHHRSRRRSSGMQMRGDYNSTTAVNSALAKTIVTISAPPVAAASASSLHLGVGGRPSSVSTLTIASVPPTLSGSGSPGGSVSGATTPLAPSLKALTPGPSNSSGHHVSFMPMTGMKRLRSSNASLGSPNGIISTVAGADTTSAPSLIDASEDQVQMRNQHRILEQCQSVQSQITTLGDVEDDDEEVSDSESESVGLALVVTTPQLESQPVEASSSSSSSVK", "length": 807, "header": "tr|A0A0B4KI18-1|DOPR2_DROME Computationally mapped isoform of Dopamine receptor 2 OS=Drosophila melanogaster OX=7227 GN=Dop1R2 PE=2 SV=1 CANONICAL=Q24563-1" }, "locus": { "chromosome": "3R", "start_pos": 29642073, "end_pos": 29631970, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0330293", "url": "https://www.ensembl.org/id/FBtr0330293" }, { "database": "Ensembl Peptide", "id": "FBpp0303325", "url": "https://www.ensembl.org/id/FBpp0303325" } ] } }, { "isoform_ac": "Q24563-1", "url": "", "sequence": { "sequence": "MVDDNGSSPEVEGAEGAGAPLLALLRVDGLNQTQTRSPSPSFFGSYNISEDVYFYFNGLPTSTELVLNATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARDGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLMASGELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCCPRKIRRKYQPTMRSKSQRFATRRCYSTCSLHGIQHVRHNSCEQTYI", "length": 539, "header": "sp|Q24563-1|DOPR2_DROME Isoform 1 of Dopamine receptor 2 OS=Drosophila melanogaster OX=7227 GN=Dop1R2 PE=2 SV=1 CANONICAL=Q24563-1" }, "locus": { "chromosome": "3R", "start_pos": 29642073, "end_pos": 29639019, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0085468", "url": "https://www.ensembl.org/id/FBtr0085468" }, { "database": "Ensembl Peptide", "id": "FBpp0084834", "url": "https://www.ensembl.org/id/FBpp0084834" } ] } }, { "isoform_ac": "Q24563-2", "url": "", "sequence": { "sequence": "MVDDNGSSPEVEGAEGAGAPLLALLRVDGLNQTQTRSPSPSFFGSYNISEDVYFYFNGLPTSTELVLNATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARDGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLMASGELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCCPRKIRRKYQPTMRSKSQCHVAAAMVAASTSFGYHSVNQIDRTLM", "length": 537, "header": "sp|Q24563-2|DOPR2_DROME Isoform 2 of Dopamine receptor 2 OS=Drosophila melanogaster OX=7227 GN=Dop1R2 PE=2 SV=1 CANONICAL=Q24563-1" }, "locus": { "chromosome": "3R", "start_pos": 29642073, "end_pos": 29632780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0085467", "url": "https://www.ensembl.org/id/FBtr0085467" }, { "database": "Ensembl Peptide", "id": "FBpp0084833", "url": "https://www.ensembl.org/id/FBpp0084833" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 31, "start_aa": "Asn", "end_pos": 31, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn31", "evidence": [ { "id": "Q24563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24563#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 47, "start_aa": "Asn", "end_pos": 47, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn47", "evidence": [ { "id": "Q24563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24563#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 5, "start_aa": "Asn", "end_pos": 5, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn5", "evidence": [ { "id": "Q24563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24563#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 68, "start_aa": "Asn", "end_pos": 68, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn68", "evidence": [ { "id": "Q24563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24563#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI18", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18" }, { "database": "UniProtKB", "id": "Q24563", "url": "https://www.uniprot.org/uniprot/Q24563" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI18", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI18", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18" }, { "database": "UniProtKB", "id": "Q24563", "url": "https://www.uniprot.org/uniprot/Q24563" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI18", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI18", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI18", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI18", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI18", "url": "https://www.uniprot.org/uniprot/A0A0B4KI18" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "Cloning and functional characterization of a novel dopamine receptor from Drosophila melanogaster.", "journal": "J. Neurosci.", "date": "1996", "authors": "Feng G., Hannan F., Hon Y.Y., Evans P.D., Hall L.M., Kousky C.T., Reale V.", "evidence": [ { "database": "UniProtKB", "id": "Q24563", "url": "https://www.uniprot.org/uniprot/Q24563" } ], "reference": [ { "type": "PubMed", "id": "8656286", "url": "https://glygen.org/publication/PubMed/8656286" } ] }, { "title": "DAMB, a novel dopamine receptor expressed specifically in Drosophila mushroom bodies.", "journal": "Neuron", "date": "1996", "authors": "Millar N.S., Davis R.L., Grotewiel M.S., Han K.-A.", "evidence": [ { "database": "UniProtKB", "id": "Q24563", "url": "https://www.uniprot.org/uniprot/Q24563" } ], "reference": [ { "type": "PubMed", "id": "8663989", "url": "https://glygen.org/publication/PubMed/8663989" } ] } ], "pathway": [ { "id": "dme:Dmel_CG18741", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG18741", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": 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