{
    "uniprot_canonical_ac": "Q12458-1",
    "uniprot_ac": "Q12458",
    "uniprot_id": "YPR1_YEAST",
    "mass": {
        "chemical_mass": 34755.0,
        "monoisotopic_mass": 34755.0
    },
    "refseq": {
        "ac": "NP_010656",
        "name": "trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010656"
    },
    "gene_names": [
        {
            "name": "YPR1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q12458",
            "id": "Q12458"
        },
        {
            "name": "D9481.8",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q12458",
            "id": "Q12458"
        },
        {
            "name": "YPR1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010656",
            "id": "NP_010656"
        }
    ],
    "protein_names": [
        {
            "name": "Putative reductase 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q12458"
        },
        {
            "name": "1.1.1.-",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q12458"
        },
        {
            "name": "trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010656",
            "id": "NP_010656"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0060074",
            "recommended_name": {
                "id": "DOID:0060074",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060074",
                "name": "ductal carcinoma in situ",
                "description": "A breast carcinoma in situ that is characterized by being non-invasive, not having spread outside of the duct into the surrounding breast tissue, has_material_basis_in abnormally proliferating cells, derives_from epithelial cells."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0060074",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060074"
                }
            ]
        },
        {
            "disease_id": "DOID:0080630",
            "recommended_name": {
                "id": "DOID:0080630",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080630",
                "name": "B-lymphoblastic leukemia/lymphoma",
                "description": "A B-cell acute lymphoblastic leukemia that is characterized by the presence of too many B-cell lymphoblasts in the blood and bone marrow."
            },
            "synonyms": [
                {
                    "id": "DOID:0080630",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080630",
                    "name": "precursor B lymphoblastic lymphoma/leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:0080630",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080630",
                    "name": "B-ALL",
                    "description": ""
                },
                {
                    "id": "DOID:0080630",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080630",
                    "name": "B lymphoblastic leukemia/lymphoma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0080630",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080630"
                }
            ]
        },
        {
            "disease_id": "DOID:0080909",
            "recommended_name": {
                "id": "DOID:0080909",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080909",
                "name": "castration-resistant prostate carcinoma",
                "description": "A prostate carcinoma that is characterized by continued growth and spread despite the surgical removal of the testes or medical intervention to block androgen production."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0080909",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080909"
                }
            ]
        },
        {
            "disease_id": "DOID:0111069",
            "recommended_name": {
                "id": "DOID:0111069",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111069",
                "name": "congenital bile acid synthesis defect 2",
                "description": "A congenital bile acid synthesis defect characterized by rapid progession of severe cholestatic liver disease, decreased levels of chenodeoxycholic acid and cholic acid in the serum and urine, and malabsorption of fat and fat-soluble vitamins that has_material_basis_in homozygous or compound heterozygous mutation in the AKR1D1 gene on chromosome 7q33."
            },
            "synonyms": [
                {
                    "id": "DOID:0111069",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111069",
                    "name": "cholestasis with delta(4)-3-oxosteroid 5-beta-reductase deficiency",
                    "description": ""
                },
                {
                    "id": "DOID:0111069",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111069",
                    "name": "CBAS2",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "congenital bile acid synthesis defect 2",
                    "description": "Congenital bile acid synthesis defect type 2 (BAS defect type 2) is an anomaly of bile acid synthesis characterized by severe and rapidly progressive cholestatic liver disease, and malabsorption of fat and fat-soluble vitamins."
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "AKR1D1 congenital bile acid synthesis defect",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "BASD2",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "CBAS2",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "bile acid synthesis defect, congenital, type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "cholestasis with delta(4)-3-oxosteroid 5-beta-reductase deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "congenital bile acid synthesis defect caused by mutation in AKR1D1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "congenital bile acid synthesis defect type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "bile acid synthesis defect, congenital, 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "cholestasis with Delta(4)-3-oxosteroid 5-Beta-reductase deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009339",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009339",
                    "name": "congenital bile acid synthesis defect, type 2",
                    "description": ""
                },
                {
                    "id": "MIM:235555",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/235555",
                    "name": "Congenital bile acid synthesis defect 2",
                    "description": "Congenital bile acid synthesis defect 2"
                }
            ],
            "evidence": [
                {
                    "id": "0111069",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111069"
                }
            ]
        },
        {
            "disease_id": "DOID:0111773",
            "recommended_name": {
                "id": "DOID:0111773",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111773",
                "name": "46,XY sex reversal 8",
                "description": "A 46 XY sex reversal characterized by an XY karyotype, phenotypically female genitalia and failure to develop secondary sexual characteristics at puberty including menstruation that has_material_basis_in homozygous or compound heterozygous mutation in the AKR1C2 gene on chromosome 10p15.1."
            },
            "synonyms": [
                {
                    "id": "DOID:0111773",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111773",
                    "name": "SRXY8",
                    "description": ""
                },
                {
                    "id": "DOID:0111773",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111773",
                    "name": "TDD",
                    "description": ""
                },
                {
                    "id": "DOID:0111773",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111773",
                    "name": "male pseudohermaphroditism due to deficiency of testicular 17,20-desmolase",
                    "description": ""
                },
                {
                    "id": "MONDO:0013664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013664",
                    "name": "46,XY disorder of sex development due to testicular 17,20-desmolase deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0013664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013664",
                    "name": "46,XY sex reversal type 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0013664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013664",
                    "name": "46XY sex reversal 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0013664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013664",
                    "name": "46XY sex reversal 8, modifier of",
                    "description": ""
                },
                {
                    "id": "MONDO:0013664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013664",
                    "name": "46,XY sex reversal 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0013664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013664",
                    "name": "SRXY8",
                    "description": ""
                },
                {
                    "id": "MONDO:0013664",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013664",
                    "name": "male pseudohermaphroditism due to deficiency of testicular 17,20-desmolase",
                    "description": ""
                },
                {
                    "id": "MIM:614279",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/614279",
                    "name": "46,XY sex reversal 8",
                    "description": "46,XY sex reversal 8"
                }
            ],
            "evidence": [
                {
                    "id": "0111773",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111773"
                }
            ]
        },
        {
            "disease_id": "DOID:10283",
            "recommended_name": {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10283",
                "name": "prostate cancer",
                "description": "A male reproductive organ cancer that is located_in the prostate."
            },
            "synonyms": [
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "NGP - new growth of prostate",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "hereditary prostate cancer",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "malignant tumor of the prostate",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostate cancer, familial",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostate neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostatic cancer",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostatic neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "tumor of the prostate",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, type 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "HPC9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, 12",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene."
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "EHBP1 familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "familial prostate cancer caused by mutation in EHBP1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, type 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "HPC12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, type 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "HPC5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, susceptibility to, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "HPC3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, susceptibility to, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "HPC4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, on chromosome 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, 13",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene."
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "MSMB familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "familial prostate cancer caused by mutation in MSMB",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, type 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "HPC13",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, type 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "HPC8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "predisposing for prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, type 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "HPC6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "prostate cancer, hereditary, 10",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "HPC10",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "prostate cancer, hereditary, 10",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "familial prostate carcinoma",
                    "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma."
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "hereditary prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "hereditary prostate carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, familial",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, hereditary",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer, hereditary, 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "HPC7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer, hereditary, 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer aggressiveness",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, 1",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene."
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "RNASEL familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "familial prostate cancer caused by mutation in RNASEL",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "HPC1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "Prca1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "prostate cancer, hereditary, 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "HPC11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "prostate cancer, hereditary, 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "prostate cancer, hereditary, 14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "HPC14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "prostate cancer, hereditary, 14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "prostate cancer, hereditary, 15",
                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "HPC15",
                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "prostate cancer, hereditary, 15",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "prostate cancer, hereditary, X-linked 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "HPCX1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "prostate cancer, hereditary, X-linked 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "prostate cancer susceptibility, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010405",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                    "name": "prostate cancer, hereditary, X-linked 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0010405",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                    "name": "HPCX2",
                    "description": ""
                },
                {
                    "id": "MONDO:0010405",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                    "name": "prostate cancer, hereditary, X-linked 2",
                    "description": ""
                },
                {
                    "id": "MIM:611868",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611868",
                    "name": "Prostate cancer, hereditary, 12",
                    "description": "Prostate cancer, hereditary, 12"
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                {
                    "id": "MIM:611928",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611928",
                    "name": "Prostate cancer, hereditary, 13",
                    "description": "Prostate cancer, hereditary, 13"
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                {
                    "id": "MIM:176807",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/176807",
                    "name": "Prostate cancer",
                    "description": "Prostate cancer"
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                {
                    "id": "MIM:601518",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/601518",
                    "name": "Prostate cancer, hereditary, 1",
                    "description": "Prostate cancer, hereditary, 1"
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                {
                    "id": "MIM:611955",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611955",
                    "name": "Prostate cancer, hereditary, 11",
                    "description": "Prostate cancer, hereditary, 11"
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            ],
            "evidence": [
                {
                    "id": "10283",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10283"
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            ]
        },
        {
            "disease_id": "DOID:10534",
            "recommended_name": {
                "id": "DOID:10534",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10534",
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                {
                    "id": "DOID:10534",
                    "resource": "Disease Ontology",
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                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric cancer",
                    "description": "A primary or metastatic malignant neoplasm involving the stomach."
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "Ca lesser curvature - stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "cancer of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric cancer risk after h. pylori infection",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant gastric neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant gastric tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant gastric tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant neoplasm of lesser curve of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant neoplasm of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant neoplasm of the stomach",
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                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant stomach neoplasm",
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                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of body of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of greater curve of stomach",
                    "description": ""
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                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of lesser curve of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of the stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of body of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of greater curve of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of lesser curve of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of stomach",
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                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of the stomach",
                    "description": ""
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                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
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                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
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                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "ca greater curvature of stomach",
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                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
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                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric cancer, intestinal",
                    "description": ""
                },
                {
                    "id": "MIM:613659",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/613659",
                    "name": "Gastric cancer",
                    "description": "Gastric cancer"
                }
            ],
            "evidence": [
                {
                    "id": "10534",
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                }
            ]
        },
        {
            "disease_id": "DOID:10591",
            "recommended_name": {
                "id": "DOID:10591",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10591",
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                },
                {
                    "id": "DOID:10591",
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                    "description": ""
                },
                {
                    "id": "DOID:10591",
                    "resource": "Disease Ontology",
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                },
                {
                    "id": "DOID:10591",
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                    "url": "http://disease-ontology.org/term/DOID:10591",
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                    "description": ""
                },
                {
                    "id": "DOID:10591",
                    "resource": "Disease Ontology",
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                    "description": ""
                },
                {
                    "id": "DOID:10591",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10591",
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                },
                {
                    "id": "DOID:10591",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10591",
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                    "description": ""
                },
                {
                    "id": "DOID:10591",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10591",
                    "name": "proteinuric hypertension of pregnancy",
                    "description": ""
                },
                {
                    "id": "DOID:10591",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10591",
                    "name": "toxaemia of pregnancy",
                    "description": ""
                },
                {
                    "id": "MONDO:0012266",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012266",
                    "name": "preeclampsia/eclampsia 4",
                    "description": "Any preeclampsia in which the cause of the disease is a mutation in the STOX1 gene."
                },
                {
                    "id": "MONDO:0012266",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012266",
                    "name": "Preeclampsia/eclampsia type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012266",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012266",
                    "name": "STOX1 preeclampsia",
                    "description": ""
                },
                {
                    "id": "MONDO:0012266",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012266",
                    "name": "preeclampsia caused by mutation in STOX1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012266",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012266",
                    "name": "preeclampsia/eclampsia 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012266",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012266",
                    "name": "PEE4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012266",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012266",
                    "name": "PREECLAMPSIA/eclampsia 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012265",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012265",
                    "name": "preeclampsia/eclampsia 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012265",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012265",
                    "name": "PEE3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012265",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012265",
                    "name": "PREECLAMPSIA/eclampsia 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012264",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012264",
                    "name": "preeclampsia/eclampsia 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012264",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012264",
                    "name": "PEE2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012264",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012264",
                    "name": "PREECLAMPSIA/eclampsia 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0100467",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100467",
                    "name": "preeclampsia/eclampsia 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0100467",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100467",
                    "name": "toxaemia of pregnancy",
                    "description": ""
                },
                {
                    "id": "MONDO:0100467",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100467",
                    "name": "toxemia of pregnancy",
                    "description": ""
                },
                {
                    "id": "MONDO:0100467",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100467",
                    "name": "PEE1",
                    "description": ""
                },
                {
                    "id": "MONDO:0100467",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100467",
                    "name": "PREECLAMPSIA/eclampsia 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0100467",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100467",
                    "name": "PREG1",
                    "description": ""
                },
                {
                    "id": "MONDO:0100467",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100467",
                    "name": "hemolysis, elevated liver enzymes, and low platelet count",
                    "description": ""
                },
                {
                    "id": "MONDO:0100467",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100467",
                    "name": "hypertension, pregnancy-induced",
                    "description": ""
                },
                {
                    "id": "MONDO:0013815",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013815",
                    "name": "bent bone dysplasia syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0013815",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013815",
                    "name": "FGFR2-related bent bone dysplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0013815",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013815",
                    "name": "perinatal lethal bent bone dysplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0013815",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013815",
                    "name": "BBDS",
                    "description": ""
                },
                {
                    "id": "MONDO:0013815",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013815",
                    "name": "bent bone dysplasia (BBD)-FGFR2 type",
                    "description": ""
                },
                {
                    "id": "MONDO:0013815",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013815",
                    "name": "bent bone dysplasia syndrome",
                    "description": ""
                },
                {
                    "id": "MIM:609404",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/609404",
                    "name": "Pre-eclampsia/eclampsia 4",
                    "description": "Pre-eclampsia/eclampsia 4"
                },
                {
                    "id": "MIM:614592",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/614592",
                    "name": "Bent bone dysplasia syndrome 1",
                    "description": "Bent bone dysplasia syndrome 1"
                }
            ],
            "evidence": [
                {
                    "id": "10591",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10591"
                }
            ]
        },
        {
            "disease_id": "DOID:11612",
            "recommended_name": {
                "id": "DOID:11612",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:11612",
                "name": "polycystic ovary syndrome",
                "description": "An ovarian dysfunction that is characterized by hyperandrogenism, polycystic ovaries, hirsutism, oligomenorrhea or amenorrhea, anovulation and excessive body weight."
            },
            "synonyms": [
                {
                    "id": "DOID:11612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11612",
                    "name": "Multicystic ovaries",
                    "description": ""
                },
                {
                    "id": "DOID:11612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11612",
                    "name": "PCOS",
                    "description": ""
                },
                {
                    "id": "DOID:11612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11612",
                    "name": "Polycystic Ovarian disease",
                    "description": ""
                },
                {
                    "id": "DOID:11612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11612",
                    "name": "Polycystic ovaries",
                    "description": ""
                },
                {
                    "id": "DOID:11612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11612",
                    "name": "Stein-Leventhal synd.",
                    "description": ""
                },
                {
                    "id": "DOID:11612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11612",
                    "name": "Stein-Leventhal syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:11612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11612",
                    "name": "polycystic ovary",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "polycystic ovary syndrome",
                    "description": "A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity."
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "PCOS",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "Stein-Leventhal synd.",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "Stein-Leventhal syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "multicystic ovaries",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "polycystic ovarian disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "polycystic ovaries",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "polycystic ovary",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "polycystic ovary syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "PCOS1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "polycystic ovary syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "PCO1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008487",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008487",
                    "name": "hyperandrogenemia",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "11612",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:11612"
                }
            ]
        },
        {
            "disease_id": "DOID:1205",
            "recommended_name": {
                "id": "DOID:1205",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:1205",
                "name": "allergic disease",
                "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods."
            },
            "synonyms": [
                {
                    "id": "DOID:1205",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1205",
                    "name": "hypersensitivity",
                    "description": ""
                },
                {
                    "id": "DOID:1205",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1205",
                    "name": "hypersensitivity reaction type I disease",
                    "description": ""
                },
                {
                    "id": "DOID:1205",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1205",
                    "name": "allergic hypersensitivity disease",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "1205",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:1205"
                }
            ]
        },
        {
            "disease_id": "DOID:1240",
            "recommended_name": {
                "id": "DOID:1240",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:1240",
                "name": "leukemia",
                "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "1240",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:1240"
                }
            ]
        },
        {
            "disease_id": "DOID:1612",
            "recommended_name": {
                "id": "DOID:1612",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:1612",
                "name": "breast cancer",
                "description": "A thoracic cancer that originates in the mammary gland."
            },
            "synonyms": [
                {
                    "id": "DOID:1612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1612",
                    "name": "breast tumor",
                    "description": ""
                },
                {
                    "id": "DOID:1612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1612",
                    "name": "malignant neoplasm of breast",
                    "description": ""
                },
                {
                    "id": "DOID:1612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1612",
                    "name": "malignant tumor of the breast",
                    "description": ""
                },
                {
                    "id": "DOID:1612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1612",
                    "name": "mammary cancer",
                    "description": ""
                },
                {
                    "id": "DOID:1612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1612",
                    "name": "mammary tumor",
                    "description": ""
                },
                {
                    "id": "DOID:1612",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1612",
                    "name": "primary breast cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "hereditary breast carcinoma",
                    "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma."
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer susceptibility, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, lobular, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, protection against, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "familial breast cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "familial breast carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "familial cancer of breast",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "familial cancer of the breast",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "hereditary breast cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "hereditary breast carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, familial",
                    "description": ""
                },
                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, familial Male",
                    "description": ""
                },
                {
                    "id": "MIM:114480",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/114480",
                    "name": "Breast cancer",
                    "description": "Breast cancer"
                }
            ],
            "evidence": [
                {
                    "id": "1612",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:1612"
                }
            ]
        },
        {
            "disease_id": "DOID:2349",
            "recommended_name": {
                "id": "DOID:2349",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:2349",
                "name": "arteriosclerosis",
                "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries."
            },
            "synonyms": [
                {
                    "id": "DOID:2349",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2349",
                    "name": "Arteriosclerotic vascular disease",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "2349",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:2349"
                }
            ]
        },
        {
            "disease_id": "DOID:3910",
            "recommended_name": {
                "id": "DOID:3910",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3910",
                "name": "lung adenocarcinoma",
                "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin."
            },
            "synonyms": [
                {
                    "id": "DOID:3910",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3910",
                    "name": "bronchogenic lung adenocarcinoma",
                    "description": ""
                },
                {
                    "id": "DOID:3910",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3910",
                    "name": "nonsmall cell adenocarcinoma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "3910",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3910"
                }
            ]
        },
        {
            "disease_id": "DOID:4195",
            "recommended_name": {
                "id": "DOID:4195",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:4195",
                "name": "hyperglycemia",
                "description": ""
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "4195",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:4195"
                }
            ]
        },
        {
            "disease_id": "DOID:4500",
            "recommended_name": {
                "id": "DOID:4500",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:4500",
                "name": "hypokalemia",
                "description": ""
            },
            "synonyms": [
                {
                    "id": "DOID:4500",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4500",
                    "name": "hypopotassemia",
                    "description": ""
                },
                {
                    "id": "DOID:4500",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4500",
                    "name": "potassium deficiency disorder",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "4500",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:4500"
                }
            ]
        },
        {
            "disease_id": "DOID:5603",
            "recommended_name": {
                "id": "DOID:5603",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:5603",
                "name": "T-cell acute lymphoblastic leukemia",
                "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood."
            },
            "synonyms": [
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "T-cell leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "acute T cell leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "precursor T-lymphoblastic lymphoma/leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "Precursor T Lymphoblastic Leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "T Acute Lymphoblastic Leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "T-cell acute lymphocytic leukaemia",
                    "description": ""
                },
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "T-cell lymphoblastic leukemia/lymphoma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "5603",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:5603"
                }
            ]
        },
        {
            "disease_id": "DOID:684",
            "recommended_name": {
                "id": "DOID:684",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:684",
                "name": "hepatocellular carcinoma",
                "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver."
            },
            "synonyms": [
                {
                    "id": "DOID:684",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:684",
                    "name": "Hepatoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular carcinoma",
                    "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation."
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "HCC",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "cancer, hepatocellular",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "carcinoma of liver",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "carcinoma of liver cells",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "carcinoma of the liver cells",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "carcinoma, hepatocellular, malignant",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatoblastoma, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular adenocarcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular carcinoma, childhood type, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular carcinoma, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver cell cancer (hepatocellular carcinoma)",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver cell carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "primary carcinoma of liver cells",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "primary carcinoma of the liver cells",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "adult hepatoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "adult primary hepatocellular carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatoblastoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatoblastoma caused by somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver and intrahepatic bile duct carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular carcinoma",
                    "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation."
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "HCC",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "cancer, hepatocellular",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "carcinoma of liver",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "carcinoma of liver cells",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "carcinoma of the liver cells",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "carcinoma, hepatocellular, malignant",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatoblastoma, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular adenocarcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular carcinoma, childhood type, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatocellular carcinoma, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver cell cancer (hepatocellular carcinoma)",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver cell carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "primary carcinoma of liver cells",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "primary carcinoma of the liver cells",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "adult hepatoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "adult primary hepatocellular carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatoblastoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "hepatoblastoma caused by somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver and intrahepatic bile duct carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007256",
                    "name": "liver cancer",
                    "description": ""
                },
                {
                    "id": "MIM:114550",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/114550",
                    "name": "Hepatocellular carcinoma",
                    "description": "Hepatocellular carcinoma"
                }
            ],
            "evidence": [
                {
                    "id": "684",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:684"
                }
            ]
        },
        {
            "disease_id": "DOID:83",
            "recommended_name": {
                "id": "DOID:83",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:83",
                "name": "cataract",
                "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision."
            },
            "synonyms": [
                {
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                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "cataract 1 multiple types",
                    "description": "Any cataract (disease) in which the cause of the disease is a mutation in the GJA8 gene."
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "CTRCT1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "Duffy linked cataract",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "GJA8 cataract (disease)",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "cataract (disease) caused by mutation in GJA8",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "cataract 1, multiple types, with or without microcornea",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "CAE1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "CZP1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "zonular pulverulent cataract 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "cataract 1, multiple types",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "cataract, Duffy-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0007285",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007285",
                    "name": "cataract, zonular pulverulent, 1",
                    "description": ""
                },
                {
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                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011060",
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                },
                {
                    "id": "MONDO:0011060",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011060",
                    "name": "cataract, age-related nuclear",
                    "description": ""
                },
                {
                    "id": "MONDO:0011060",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011060",
                    "name": "nuclear sclerosis of the lens",
                    "description": ""
                },
                {
                    "id": "MIM:116200",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/116200",
                    "name": "Cataract 1, multiple types",
                    "description": "Cataract 1, multiple types"
                }
            ],
            "evidence": [
                {
                    "id": "83",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:83"
                }
            ]
        },
        {
            "disease_id": "DOID:8947",
            "recommended_name": {
                "id": "DOID:8947",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:8947",
                "name": "diabetic retinopathy",
                "description": ""
            },
            "synonyms": [
                {
                    "id": "DOID:8947",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8947",
                    "name": "Retinal abnormality - diabetes-related",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "8947",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:8947"
                }
            ]
        },
        {
            "disease_id": "DOID:9352",
            "recommended_name": {
                "id": "DOID:9352",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:9352",
                "name": "type 2 diabetes mellitus",
                "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin."
            },
            "synonyms": [
                {
                    "id": "DOID:9352",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9352",
                    "name": "NIDDM",
                    "description": ""
                },
                {
                    "id": "DOID:9352",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9352",
                    "name": "non-insulin-dependent diabetes mellitus",
                    "description": ""
                },
                {
                    "id": "DOID:9352",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9352",
                    "name": "type 2 diabetes",
                    "description": ""
                },
                {
                    "id": "DOID:9352",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9352",
                    "name": "type II diabetes mellitus",
                    "description": ""
                },
                {
                    "id": "DOID:9352",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9352",
                    "name": "insulin resistance",
                    "description": ""
                },
                {
                    "id": "MONDO:0011955",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011955",
                    "name": "diabetes mellitus, noninsulin-dependent, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0011955",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011955",
                    "name": "diabetes mellitus, noninsulin-dependent, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0011955",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011955",
                    "name": "diabetes mellitus, noninsulin-dependent, type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0011955",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011955",
                    "name": "Niddm4",
                    "description": ""
                },
                {
                    "id": "MONDO:0011955",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011955",
                    "name": "noninsulin-dependent diabetes mellitus 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0005148",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005148",
                    "name": "type 2 diabetes mellitus",
                    "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity."
                },
                {
                    "id": "MONDO:0005148",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005148",
                    "name": "NIDDM",
                    "description": ""
                },
                {
                    "id": "MONDO:0005148",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005148",
                    "name": "T2DM - type 2 diabetes mellitus",
                    "description": ""
                },
                {
                    "id": "MONDO:0005148",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005148",
                    "name": "adult onset diabetes",
                    "description": ""
                },
                {
                    "id": "MONDO:0005148",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005148",
                    "name": "adult-onset diabetes",
                    "description": ""
                },
                {
                    "id": "MONDO:0005148",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005148",
                    "name": "diabetes mellitis type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0005148",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005148",
                    "name": "diabetes mellitis type II",
                    "description": ""
                },
                {
                    "id": "MONDO:0005148",
                    "resource": "MONDO",
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                    "url": "https://www.yeastgenome.org/locus/Q12458"
                }
            ],
            "site_lbl": "Ser172"
        }
    ],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [
        {
            "title": "Global analysis of protein expression in yeast.",
            "journal": "Nature",
            "date": "2003",
            "authors": "Dephoure N., Weissman J.S., Howson R.W., Huh W.-K., O'Shea E.K., Belle A., Bower K., Ghaemmaghami S.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q12458",
                    "url": "https://www.uniprot.org/uniprot/Q12458"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "14562106",
                    "url": "https://glygen.org/publication/PubMed/14562106"
                }
            ]
        },
        {
            "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.",
            "journal": "Molecular & cellular proteomics : MCP",
            "date": "2008-07",
            "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "Q12458",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q12458"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18407956",
                    "url": "https://glygen.org/publication/PubMed/18407956"
                }
            ]
        },
        {
            "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.",
            "journal": "G3 (Bethesda)",
            "date": "2014",
            "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q12458",
                    "url": "https://www.uniprot.org/uniprot/Q12458"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "24374639",
                    "url": "https://glygen.org/publication/PubMed/24374639"
                }
            ]
        },
        {
            "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.",
            "journal": "Nature",
            "date": "1997",
            "authors": "Andrews S., Bahr A., Bloecker H., Brandt P., Connor R., Du Z., Fulton L., Gentles S., Hawkins J., Hillier L.W., Johnson D., Latreille P., Mardis E., Mewes H.-W., Miller N., Niblett D., Oliver K., Schaefer M., Scharfe M., Vaudin M., Wambutt R., Waterston R., Wedler H., Wilson R., Chen E., Le T., Verhasselt P., Bowman S., Hunt S., Wagner G., Chung E., Nakahara K., Botstein D., Brueckner M., Davis R.W., Lin D., Hankeln T., Schneider C., Schmidt E.R., Duncan M., Favello A., Kucaba T., Rifkin L., Trevaskis E., Wohldman P., Barrell B.G., Rieger M., Berno A., Schroeder M., Ding H., Oh C., Oefner P., Schwarz S., Woelfl S., Kleine K., Becker A., Prydz H., Cooper J., Arnold W., Eide L.G., Kraemer C., Lashkari D., Allen E., Jimenez A., Kuester H., Hoheisel J.D., Pauley A., Paulin L., Brown D., Jaeger W., Volckaert G., Hyman R.W., Andre B., Perez-Alonso M., Araujo R., Komp C., Lew H., Namath A., Roberts D., Paricio N., Boskovic J., Louis E.J., Mulligan J.T., Delaveau T., Greco T., Johnston L., Nhan M., Jones L., Odell C., Menezes S., Johnston M., Pohl T.M., Harris D.E., Schramm S., McDonald S., Salom D., Bargues M., Cherry J.M., Ballesta J.P.G., Churcher C.M., Dedman K., Dietrich F.S., Dujon B., Goffeau A., Hamlin N., Hani J., Jacq C., Mueller-Auer S., Perea J., Perez-Ortin J.E., Rajandream M.A., Remacha M.A., Revuelta J.L., Vissers S., Walsh S.V., Zollner A., del Rey F., Jonniaux J.-L., Purnelle B., Saiz J.E., Urrestarazu L.A., Voet M., Wilcox L., Albermann K., Alt-Moerbe J., Aviles E., Baron L., Biteau N., Blugeon C., Brinkman R., Buitrago M.J., Carpenter J., Coster F., Garcia-Cantalejo J.M., Gattung S., Gomez-Peris A., Granotier C., Hallsworth K., Hanemann V., Heumann K., Hunicke-Smith S., Jier M., Kirsten J., Laamanen P., Langston Y., Legros Y., Moeller-Rieker S., Monnet A., Moro M., Mosedale D., Murphy L.D., Nussbaumer B., Peluso D., Petel F.X., Rasmussen S.W., Richards C., Riles L., Saluz H.P., Saren A.-M., Scholler P., Shogren T., Shore L., Shroff N., Soler-Mira A., Taich A., Vignati D., Wedler E., Winant A., Yelton M.A., Zaccaria P.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q12458",
                    "url": "https://www.uniprot.org/uniprot/Q12458"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "9169867",
                    "url": "https://glygen.org/publication/PubMed/9169867"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "sce:YDR368W",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YDR368W",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P52895-1",
            "protein_name": "Aldo-keto reductase family 1 member C2",
            "gene_name": "AKR1C2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY",
                "length": 323
            },
            "evidence": [
                {
                    "id": "Q12458",
                    "url": "https://omabrowser.org/oma/group/Q12458/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q12458",
                                "url": "https://www.uniprot.org/uniprot/Q12458"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q12458",
                                "url": "https://www.uniprot.org/uniprot/Q12458"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q12458",
                                "url": "https://www.uniprot.org/uniprot/Q12458"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "alditol:NADP+ 1-oxidoreductase activity",
                        "id": "GO:0004032",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004032",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q12458",
                                "url": "https://www.uniprot.org/uniprot/Q12458"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "carbonyl reductase (NADPH) activity",
                        "id": "GO:0004090",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004090",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q12458",
                                "url": "https://www.uniprot.org/uniprot/Q12458"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "cellular response to oxidative stress",
                        "id": "GO:0034599",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q12458",
                                "url": "https://www.uniprot.org/uniprot/Q12458"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "D-xylose catabolic process",
                        "id": "GO:0042843",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042843",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q12458",
                                "url": "https://www.uniprot.org/uniprot/Q12458"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "arabinose catabolic process",
                        "id": "GO:0019568",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019568",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q12458",
                                "url": "https://www.uniprot.org/uniprot/Q12458"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 170,
            "end_pos": 172,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 290,
            "end_pos": 292,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 7,
            "end_pos": 9,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 95,
            "end_pos": 97,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [
        {
            "id": "R-SCE-192033",
            "name": "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, endoplasmic reticulum membrane",
            "input_participant_list": [
                "R-ALL-192136"
            ],
            "output_participant_list": [],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-192033",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-192033"
                }
            ]
        },
        {
            "id": "R-SCE-192036",
            "name": "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [
                "R-ALL-192064"
            ],
            "output_participant_list": [
                "R-ALL-192087"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-192036",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-192036"
                }
            ]
        },
        {
            "id": "R-SCE-192067",
            "name": "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, endoplasmic reticulum membrane",
            "input_participant_list": [
                "R-ALL-192195"
            ],
            "output_participant_list": [],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-192067",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-192067"
                }
            ]
        },
        {
            "id": "R-SCE-192160",
            "name": "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [
                "R-ALL-191980"
            ],
            "output_participant_list": [
                "R-ALL-192030"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-192160",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-192160"
                }
            ]
        },
        {
            "id": "R-SCE-193746",
            "name": "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, endoplasmic reticulum membrane",
            "input_participant_list": [
                "R-ALL-193724"
            ],
            "output_participant_list": [
                "R-ALL-193760"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-193746",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-193746"
                }
            ]
        },
        {
            "id": "R-SCE-193755",
            "name": "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, endoplasmic reticulum membrane",
            "input_participant_list": [
                "R-ALL-193745"
            ],
            "output_participant_list": [],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-193755",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-193755"
                }
            ]
        },
        {
            "id": "R-SCE-193758",
            "name": "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [],
            "output_participant_list": [
                "R-ALL-213285"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-193758",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-193758"
                }
            ]
        },
        {
            "id": "R-SCE-193781",
            "name": "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [
                "R-ALL-193707"
            ],
            "output_participant_list": [
                "R-ALL-193728"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-193781",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-193781"
                }
            ]
        },
        {
            "id": "R-SCE-193800",
            "name": "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [
                "R-ALL-193829"
            ],
            "output_participant_list": [
                "R-ALL-193843"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-193800",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-193800"
                }
            ]
        },
        {
            "id": "R-SCE-193821",
            "name": "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, endoplasmic reticulum membrane",
            "input_participant_list": [
                "R-ALL-9617026"
            ],
            "output_participant_list": [],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-193821",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-193821"
                }
            ]
        },
        {
            "id": "R-SCE-193824",
            "name": "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, endoplasmic reticulum membrane",
            "input_participant_list": [
                "R-ALL-193835"
            ],
            "output_participant_list": [],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-193824",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-193824"
                }
            ]
        },
        {
            "id": "R-SCE-193841",
            "name": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [
                "R-ALL-193830"
            ],
            "output_participant_list": [
                "R-ALL-193842"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-193841",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-193841"
                }
            ]
        },
        {
            "id": "R-SCE-196060",
            "name": "Reduction of isocaproaldehyde to 4-methylpentan-1-ol",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [
                "R-ALL-196095"
            ],
            "output_participant_list": [
                "R-ALL-196066"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-196060",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-196060"
                }
            ]
        },
        {
            "id": "R-SCE-2161549",
            "name": "PGH2 is reduced to PGF2a by AKR1C3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [
                "R-ALL-265283"
            ],
            "output_participant_list": [
                "R-ALL-879535"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-2161549",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-2161549"
                }
            ]
        },
        {
            "id": "R-SCE-2161614",
            "name": "PGD2 is reduced to 11-epi-PGF2a by AKRIC3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [
                "R-ALL-879629"
            ],
            "output_participant_list": [
                "R-ALL-2142710"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-2161614",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-2161614"
                }
            ]
        },
        {
            "id": "R-SCE-5615668",
            "name": "AKR1C3 reduces atRAL to atROL",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, endoplasmic reticulum membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-5615668",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-5615668"
                }
            ]
        },
        {
            "id": "R-SCE-5652172",
            "name": "AKR1B1 reduces Glc to D-sorbitol",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [],
            "output_participant_list": [
                "R-ALL-5652213"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-5652172",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-5652172"
                }
            ]
        },
        {
            "id": "R-SCE-5696822",
            "name": "AKR1B15 reduces EST17b to E1",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "mitochondrial matrix",
            "input_participant_list": [
                "R-ALL-5696835"
            ],
            "output_participant_list": [
                "R-ALL-113600",
                "R-ALL-113529",
                "R-ALL-5696848"
            ],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-5696822",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-5696822"
                }
            ]
        },
        {
            "id": "R-SCE-9758682",
            "name": "AKR1C1 hydrogenates PREDN,PREDL",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q07551-1",
                "P38115-1",
                "P47137-1",
                "Q12458-1",
                "P14065-1"
            ],
            "evidence": [
                {
                    "id": "R-SCE-9758682",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-SCE-9758682"
                }
            ]
        }
    ],
    "reaction_participants": [
        {
            "participant_id": "R-ALL-113529",
            "participant_name": "H+ [mitochondrial matrix]",
            "crossref": [
                {
                    "id": "C00080",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "15378",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0059597",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "8145820",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "C00080",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "15378",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0059597",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "8145820",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "C00080",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "15378",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0059597",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "8145820",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "C00080",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "15378",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0059597",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "8145820",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "C00080",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "15378",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0059597",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "8145820",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "C00080",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "15378",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0059597",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "8145820",
                    "database": "PubChem Substance",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-ALL-113600",
            "participant_name": "NADPH [mitochondrial matrix]",
            "crossref": [
                {
                    "id": "C00005",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "16474",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0000221",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "3041",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "8145663",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "000008215411",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "HMDB0000221",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "8145663",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "C00005",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "000008215411",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "3041",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "16474",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C00005",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "16474",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0000221",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "3041",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "8145663",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "000008215411",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "16474",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "3041",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "000008215411",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "HMDB0000221",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "C00005",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "8145663",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "C00005",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "16474",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0000221",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "3041",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "8145663",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "000008215411",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "C00005",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "16474",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "HMDB0000221",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "3041",
                    "database": "Guide to Pharmacology - Ligands",
                    "url": ""
                },
                {
                    "id": "8145663",
                    "database": "PubChem Substance",
                    "url": ""
                },
                {
                    "id": "000008215411",
                    "database": "ZINC",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-ALL-191980",
            "participant_name": "5beta-cholestan-7alpha-ol-3-one [cytosol]",
            "crossref": [
                {
                    "id": "HMDB0006892",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "2290",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05451",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "000013543210",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "C05451",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "2290",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "000013543210",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "HMDB0006892",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "000013543210",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "C05451",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "HMDB0006892",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "2290",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05451",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "2290",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "000013543210",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "HMDB0006892",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "C05451",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "000013543210",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "HMDB0006892",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "2290",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05451",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "2290",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "000013543210",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "HMDB0006892",
                    "database": "HMDB Metabolite",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-ALL-192030",
            "participant_name": "5beta-cholestan-3alpha,7alpha-diol [cytosol]",
            "crossref": [
                {
                    "id": "28047",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05452",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "000013512028",
                    "database": "ZINC",
                    "url": ""
                },
                {
                    "id": "HMDB0006893",
                    "database": "HMDB Metabolite",
                    "url": ""
                },
                {
                    "id": "28047",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05452",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "000013512028",
                    "database": "ZINC",
                    "url": ""
                },
                {
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