{
    "uniprot_canonical_ac": "Q06506-1",
    "uniprot_ac": "Q06506",
    "uniprot_id": "RRP9_YEAST",
    "mass": {
        "chemical_mass": 65054.0,
        "monoisotopic_mass": 65054.0
    },
    "refseq": {
        "ac": "NP_015463",
        "name": "Rrp9p",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015463"
    },
    "gene_names": [
        {
            "name": "RRP9",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q06506",
            "id": "Q06506"
        },
        {
            "name": "RRP9",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015463",
            "id": "NP_015463"
        }
    ],
    "protein_names": [
        {
            "name": "Ribosomal RNA-processing protein 9",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q06506"
        },
        {
            "name": "Rrp9p",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015463",
            "id": "NP_015463"
        }
    ],
    "function": [
        {
            "annotation": "Involved in nucleolar processing of pre-18S ribosomal RNA. Required for efficient pre-rRNA cleavage at sites A0, A1 and A2, and biosynthesis of 18S rRNA.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506#function"
                },
                {
                    "database": "PubMed",
                    "id": "11105764",
                    "url": "https://glygen.org/publication/PubMed/11105764"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Saccharomyces cerevisiae S288C",
            "taxid": 559292,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                }
            ],
            "common_name": "Yeast"
        }
    ],
    "gene": [
        {
            "name": "RRP9",
            "url": "https://www.uniprot.org/uniprot/Q06506",
            "locus": {}
        }
    ],
    "crossref": [
        {
            "id": "856255",
            "url": "https://www.ncbi.nlm.nih.gov/gene/856255",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q06506",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q06506*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR001680",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR015943",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036322",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "sce:YPR137W",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YPR137W",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "RIWKITE",
            "url": "https://omabrowser.org/oma/group/RIWKITE/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "72797at2759",
            "url": "http://www.orthodb.org/?query=72797at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR19865",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19865",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR19865:SF0",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19865:SF0",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4J0X",
            "url": "https://www.rcsb.org/structure/4J0X",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "5JPQ",
            "url": "https://www.rcsb.org/structure/5JPQ",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "5TZS",
            "url": "https://www.rcsb.org/structure/5TZS",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "5WLC",
            "url": "https://www.rcsb.org/structure/5WLC",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "5WYJ",
            "url": "https://www.rcsb.org/structure/5WYJ",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "5WYK",
            "url": "https://www.rcsb.org/structure/5WYK",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6KE6",
            "url": "https://www.rcsb.org/structure/6KE6",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6LQP",
            "url": "https://www.rcsb.org/structure/6LQP",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6LQQ",
            "url": "https://www.rcsb.org/structure/6LQQ",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6LQR",
            "url": "https://www.rcsb.org/structure/6LQR",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6LQS",
            "url": "https://www.rcsb.org/structure/6LQS",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6LQT",
            "url": "https://www.rcsb.org/structure/6LQT",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6LQU",
            "url": "https://www.rcsb.org/structure/6LQU",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6LQV",
            "url": "https://www.rcsb.org/structure/6LQV",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6ND4",
            "url": "https://www.rcsb.org/structure/6ND4",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6ZQA",
            "url": "https://www.rcsb.org/structure/6ZQA",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6ZQB",
            "url": "https://www.rcsb.org/structure/6ZQB",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6ZQC",
            "url": "https://www.rcsb.org/structure/6ZQC",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6ZQD",
            "url": "https://www.rcsb.org/structure/6ZQD",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "6ZQE",
            "url": "https://www.rcsb.org/structure/6ZQE",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "7AJT",
            "url": "https://www.rcsb.org/structure/7AJT",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "7AJU",
            "url": "https://www.rcsb.org/structure/7AJU",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "7D4I",
            "url": "https://www.rcsb.org/structure/7D4I",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "7D5S",
            "url": "https://www.rcsb.org/structure/7D5S",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "7D5T",
            "url": "https://www.rcsb.org/structure/7D5T",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "7D63",
            "url": "https://www.rcsb.org/structure/7D63",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "PF00400",
            "url": "http://pfam.xfam.org/family/PF00400",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q06506",
            "url": "http://purl.obolibrary.org/obo/PR_Q06506",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_015463",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015463",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "S000006341",
            "url": "https://www.yeastgenome.org/locus/S000006341",
            "database": "SGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "Q06506",
            "url": "https://www.uniprot.org/uniprot/Q06506",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q06506-1",
            "url": "https://www.uniprot.org/uniprot/Q06506-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSDVTQQKKRKRSKGEVNPSKPTVDEEITDPSSNEDEQLEVSDEEDALESEEEFEGENPADKRRRLAKQYLENLKSEANDILTDNRNAEEKDLNNLKERTIDEYNNFDAGDLDKDIIASRLKEDVAEQQGRVFRYFGDKLLISEAKQSFTRVGENNLTCISCFQPVLNKYTFEESSNGDKNKGRLFAYTVSKDLQLTKYDITDFSKRPKKLKYAKGGAKYIPTSKHEYENTTEGHYDEILTVAASPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIVEDISALAMERCVTVGARDRTAMLWKIPDETRLTFRGGDEPQKLLRRWMKENAKEGEDGEVKYPDESEAPLFFCEGSIDVVSMVDDFHFITGSDNGNICLWSLAKKKPIFTERIAHGILPEPSFNDISGETDEELRKRQLQGKKLLQPFWITSLYAIPYSNVFISGSWSGSLKVWKISDNLRSFELLGELSGAKGVVTKIQVVESGKHGKEKFRILASIAKEHRLGRWIANVSGARNGIYSAVIDQTGF",
        "length": 573,
        "header": "sp|Q06506-1|RRP9_YEAST Isoform 1 of Ribosomal RNA-processing protein 9  OS=Saccharomyces cerevisiae S288C OX=559292 GN=RRP9 PE=1 SV=1 CANONICAL=Q06506-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q06506-1",
            "url": "",
            "sequence": {
                "sequence": "MSDVTQQKKRKRSKGEVNPSKPTVDEEITDPSSNEDEQLEVSDEEDALESEEEFEGENPADKRRRLAKQYLENLKSEANDILTDNRNAEEKDLNNLKERTIDEYNNFDAGDLDKDIIASRLKEDVAEQQGRVFRYFGDKLLISEAKQSFTRVGENNLTCISCFQPVLNKYTFEESSNGDKNKGRLFAYTVSKDLQLTKYDITDFSKRPKKLKYAKGGAKYIPTSKHEYENTTEGHYDEILTVAASPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIVEDISALAMERCVTVGARDRTAMLWKIPDETRLTFRGGDEPQKLLRRWMKENAKEGEDGEVKYPDESEAPLFFCEGSIDVVSMVDDFHFITGSDNGNICLWSLAKKKPIFTERIAHGILPEPSFNDISGETDEELRKRQLQGKKLLQPFWITSLYAIPYSNVFISGSWSGSLKVWKISDNLRSFELLGELSGAKGVVTKIQVVESGKHGKEKFRILASIAKEHRLGRWIANVSGARNGIYSAVIDQTGF",
                "length": 573,
                "header": "sp|Q06506-1|RRP9_YEAST Isoform 1 of Ribosomal RNA-processing protein 9  OS=Saccharomyces cerevisiae S288C OX=559292 GN=RRP9 PE=1 SV=1 CANONICAL=Q06506-1"
            },
            "locus": {
                "chromosome": "XVI",
                "start_pos": 804077,
                "end_pos": 802359,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "YPR137W_mRNA",
                        "url": "https://www.ensembl.org/id/YPR137W_mRNA"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "YPR137W",
                        "url": "https://www.ensembl.org/id/YPR137W"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 176,
            "end_pos": 176,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "",
            "evidence": [
                {
                    "database": "SGD",
                    "id": "Q06506",
                    "url": "https://www.yeastgenome.org/locus/Q06506"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q06506",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506"
                },
                {
                    "database": "PubMed",
                    "id": "23749301",
                    "url": "https://glygen.org/publication/PubMed/23749301"
                }
            ],
            "site_lbl": "Ser176"
        },
        {
            "start_pos": 29,
            "end_pos": 29,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "Q06506",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506"
                },
                {
                    "database": "PubMed",
                    "id": "19795423",
                    "url": "https://glygen.org/publication/PubMed/19795423"
                },
                {
                    "database": "PubMed",
                    "id": "19823750",
                    "url": "https://glygen.org/publication/PubMed/19823750"
                }
            ],
            "site_lbl": "Thr29"
        },
        {
            "start_pos": 50,
            "end_pos": 50,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                },
                {
                    "database": "PubMed",
                    "id": "18407956",
                    "url": "https://glygen.org/publication/PubMed/18407956"
                },
                {
                    "database": "SGD",
                    "id": "Q06506",
                    "url": "https://www.yeastgenome.org/locus/Q06506"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q06506",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506"
                }
            ],
            "site_lbl": "Ser50"
        }
    ],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Yeast Rrp9p is an evolutionarily conserved U3 snoRNP protein essential for early pre-rRNA processing cleavages and requires box C for its association.",
            "journal": "RNA",
            "date": "2000",
            "authors": "van Venrooij W.J., Vos H.R., Faber A.W., Raue H.A., Venema J.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11105764",
                    "url": "https://glygen.org/publication/PubMed/11105764"
                }
            ]
        },
        {
            "title": "A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.",
            "journal": "Nature",
            "date": "2002",
            "authors": "Dragon F, Gallagher JE, Compagnone-Post PA, Mitchell BM, Porwancher KA, Wehner KA, Wormsley S, Settlage RE, Shabanowitz J, Osheim Y, Beyer AL, Hunt DF, Baserga SJ",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12068309",
                    "url": "https://glygen.org/publication/PubMed/12068309"
                }
            ]
        },
        {
            "title": "Global analysis of protein localization in budding yeast.",
            "journal": "Nature",
            "date": "2003",
            "authors": "Weissman J.S., Carroll A.S., Howson R.W., Huh W.-K., O'Shea E.K., Falvo J.V., Gerke L.C.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "14562095",
                    "url": "https://glygen.org/publication/PubMed/14562095"
                }
            ]
        },
        {
            "title": "Global analysis of protein expression in yeast.",
            "journal": "Nature",
            "date": "2003",
            "authors": "Dephoure N., Weissman J.S., Howson R.W., Huh W.-K., O'Shea E.K., Belle A., Bower K., Ghaemmaghami S.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "14562106",
                    "url": "https://glygen.org/publication/PubMed/14562106"
                }
            ]
        },
        {
            "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.",
            "journal": "Molecular & cellular proteomics : MCP",
            "date": "2008-07",
            "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q06506",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18407956",
                    "url": "https://glygen.org/publication/PubMed/18407956"
                }
            ]
        },
        {
            "title": "High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast.",
            "journal": "Proteomics",
            "date": "2009-10",
            "authors": "Gnad Florian, de Godoy Lyris M F, Cox J\u00fcrgen, Neuhauser Nadin, Ren Shubin, Olsen Jesper V, Mann Matthias",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "Q06506",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19795423",
                    "url": "https://glygen.org/publication/PubMed/19795423"
                }
            ]
        },
        {
            "title": "Global analysis of the yeast osmotic stress response by quantitative proteomics.",
            "journal": "Molecular bioSystems",
            "date": "2009-11",
            "authors": "Soufi Boumediene, Kelstrup Christian D, Stoehr Gabriele, Fr\u00f6hlich Florian, Walther Tobias C, Olsen Jesper V",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "Q06506",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19823750",
                    "url": "https://glygen.org/publication/PubMed/19823750"
                }
            ]
        },
        {
            "title": "The DEAD-box RNA helicase-like Utp25 is an SSU processome component.",
            "journal": "RNA",
            "date": "2010",
            "authors": "Baserga S.J., Charette J.M.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "20884785",
                    "url": "https://glygen.org/publication/PubMed/20884785"
                }
            ]
        },
        {
            "title": "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.",
            "journal": "Proc. Natl. Acad. Sci. U.S.A.",
            "date": "2012",
            "authors": "Van Damme P, Lasa M, Polevoda B, Gazquez C, Elosegui-Artola A, Kim DS, De Juan-Pardo E, Demeyer K, Hole K, Larrea E, Timmerman E, Prieto J, Arnesen T, Sherman F, Gevaert K, Aldabe R",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22814378",
                    "url": "https://glygen.org/publication/PubMed/22814378"
                }
            ]
        },
        {
            "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.",
            "journal": "Nature methods",
            "date": "2013-07",
            "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "Q06506",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "23749301",
                    "url": "https://glygen.org/publication/PubMed/23749301"
                }
            ]
        },
        {
            "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.",
            "journal": "G3 (Bethesda)",
            "date": "2014",
            "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "24374639",
                    "url": "https://glygen.org/publication/PubMed/24374639"
                }
            ]
        },
        {
            "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.",
            "journal": "Nature",
            "date": "1997",
            "authors": "Ansorge W., Davis K., Duesterhoeft A., Hillier L.W., Mewes H.-W., Pearson D., Schaefer M., Scharfe M., Wambutt R., Wang Y., Wedler H., Hall J., Bowman S., Chung E., Benes V., Botstein D., Brueckner M., Davis R.W., Lin A., Lin D., Duncan M., Barrell B.G., Rieger M., Ahmed A., Schroeder M., Oefner P., Delius H., Kleine K., Floeth M., Bussey H., Voss H., Lashkari D., Allen E., Dubois E., Hyman R.W., Aparicio A., Araujo R., Kalman S., Komp C., Kurdi O., Lew H., Namath A., Roberts D., Friesen J.D., Louis E.J., Johnston M., Pohl T.M., Schramm S., Cherry J.M., Badcock K., Churcher C.M., DiPaolo T., Dietrich F.S., Goffeau A., Hani J., Messenguy F., Mueller-Auer S., Rajandream M.A., Scherens B., Vissers S., Walsh S.V., Zollner A., Fortin N., Purnelle B., Sdicu A.-M., Storms R.K., Urrestarazu L.A., Vierendeels F., Vo D.H., Zhong W.-W., Albermann K., Carpenter J., Coster F., Fritz C., Hebling U., Heumann K., Hilbert H., Hunicke-Smith S., Marathe R., Mirtipati S., Moestl D., Nentwich U., Petel F.X., Rechmann S., Riles L., Tettelin H., Ushinsky S., Wedler E., Winnett E.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q06506",
                    "url": "https://www.uniprot.org/uniprot/Q06506"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "9169875",
                    "url": "https://glygen.org/publication/PubMed/9169875"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "sce:YPR137W",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YPR137W",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "O43818-1",
            "protein_name": "U3 small nucleolar RNA-interacting protein 2",
            "gene_name": "RRP9",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSATAAARKRGKPASGAGAGAGAGKRRRKADSAGDRGKSKGGGKMNEEISSDSESESLAPRKPEEEEEEELEETAQEKKLRLAKLYLEQLRQQEEEKAEARAFEEDQVAGRLKEDVLEQRGRLQKLVAKEIQAPASADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDCIHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLRGEPGLEQPFWISSVAALLNTDLVATGSHSSCVRLWQCGEGFRQLDLLCDIPLVGFINSLKFSSSGDFLVAGVGQEHRLGRWWRIKEARNSVCIIPLRRVPVPPAAGS",
                "length": 475
            },
            "evidence": [
                {
                    "id": "Q06506",
                    "url": "https://omabrowser.org/oma/group/Q06506/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q91WM3-1",
            "protein_name": "U3 small nucleolar RNA-interacting protein 2",
            "gene_name": "Rrp9",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSTAVATRKRAKPAPGPGAAPVAGKRRRKVDSAADRGKSKGGGKMNEEISSDSESESLAPRKTEEEEEEELEETAQEKKLRLAKLYLEQLRQQEEEKAEARAFEEDQVAGRLKEDVLEQRGRLQKSVAKEIQAPAPTDIRVLRGHQLSITCLVITPDDLAIFSAAKDCTIIKWSVETGRKLHVIPRAKKGAQGQPAGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRKGTHQLYSTSHDRSVKVWNAAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDCIHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLHGEPGLEQPFWVSSVAALLNTDLVATGSHNARVRLWQCGEGFRQLDPLCDIPLVGFINSLKFSSAGDFLVAGVGQEHRLGRWWRIKEARNSVCIIPLRRLPVSPVAGS",
                "length": 475
            },
            "evidence": [
                {
                    "id": "Q06506",
                    "url": "https://omabrowser.org/oma/group/Q06506/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "nucleoplasm",
                        "id": "GO:0005654",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleolus",
                        "id": "GO:0005730",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "box C/D RNP complex",
                        "id": "GO:0031428",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031428",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "90S preribosome",
                        "id": "GO:0030686",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "small-subunit processome",
                        "id": "GO:0032040",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "snoRNA binding",
                        "id": "GO:0030515",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "U3 snoRNA binding",
                        "id": "GO:0034511",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 4,
                "go_terms": [
                    {
                        "name": "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",
                        "id": "GO:0000447",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000447",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",
                        "id": "GO:0000472",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000472",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",
                        "id": "GO:0000480",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000480",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "maturation of SSU-rRNA",
                        "id": "GO:0030490",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q06506",
                                "url": "https://www.uniprot.org/uniprot/Q06506"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 156,
            "end_pos": 158,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 230,
            "end_pos": 232,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 555,
            "end_pos": 557,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 3
                },
                {
                    "field": "total_sites",
                    "count": 3
                }
            ],
            "sort_fields": [
                "start_pos",
                "end_pos",
                "kinase_uniprot_canonical_ac",
                "kinase_gene_name",
                "residue",
                "comment",
                "site_lbl"
            ]
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 12
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}