{ "uniprot_canonical_ac": "Q05043-1", "uniprot_ac": "Q05043", "uniprot_id": "RSF1_YEAST", "mass": { "chemical_mass": 43460.0, "monoisotopic_mass": 43460.0 }, "refseq": { "ac": "NP_013743", "name": "Rsf1p", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013743" }, "gene_names": [ { "name": "RSF1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q05043", "id": "Q05043" }, { "name": "RSF1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013743", "id": "NP_013743" }, { "name": "YM9973.03", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q05043", "id": "Q05043" } ], "protein_names": [ { "name": "Respiration factor 1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q05043" }, { "name": "Rsf1p", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013743", "id": "NP_013743" } ], "function": [ { "annotation": "Mitochondrial and nuclear transcriptional activator required for respiratory growth.", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043#function" }, { "database": "PubMed", "id": "16464826", "url": "https://glygen.org/publication/PubMed/16464826" }, { "database": "PubMed", "id": "17003135", "url": "https://glygen.org/publication/PubMed/17003135" }, { "database": "PubMed", "id": "12734673", "url": "https://glygen.org/publication/PubMed/12734673" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" } ], "common_name": "Yeast" } ], "gene": [ { "name": "RSF1", "url": "https://www.uniprot.org/uniprot/Q05043", "locus": {} } ], "crossref": [ { "id": "855045", "url": "https://www.ncbi.nlm.nih.gov/gene/855045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YMR030W", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YMR030W", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRTKRIC", "url": "https://omabrowser.org/oma/group/RRTKRIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2026034at2759", "url": "http://www.orthodb.org/?query=2026034at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF14876", "url": "http://pfam.xfam.org/family/PF14876", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q05043", "url": "http://purl.obolibrary.org/obo/PR_Q05043", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_013743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013743", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000004632", "url": "https://www.yeastgenome.org/locus/S000004632", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05043-1", "url": "https://www.uniprot.org/uniprot/Q05043-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDLNPEMGKFATTKGPPQDNRGMVDIATLPNFPANRSGTPREEMYLAPNKMETPRILNMNMVPDYLQKENFSPDFSSATVSAKSSPVNVTHDESLPLGTIESNSTKDSKYAVQRQQQQVVDFIENNMQLLSSETLNFRSDIMKTLELPIPKRRDIKGNHLSKLLFAKSPLTINTYCQFYDRRTKRICNQEMIWKDKNSREKHGSRKYQRHLSKVHDVQLTPNNFTEFFDHNSPLFQECYDYQSRLMRDLLVEPDAKFKEKKKKKKGDVNGNHPETGSSLINHQVQQQNVRELQSKIAMNDLIEILIDLNIPFSVLDYQPMRNWLIKYSIISTDTLPDEVYFKTDPGVNELEHNSSNLNNSNSGTPHNHNQNQHTN", "length": 376, "header": "sp|Q05043-1|RSF1_YEAST Isoform 1 of Respiration factor 1 OS=Saccharomyces cerevisiae S288C OX=559292 GN=RSF1 PE=1 SV=1 CANONICAL=Q05043-1" }, "isoforms": [ { "isoform_ac": "Q05043-1", "url": "", "sequence": { "sequence": "MKDLNPEMGKFATTKGPPQDNRGMVDIATLPNFPANRSGTPREEMYLAPNKMETPRILNMNMVPDYLQKENFSPDFSSATVSAKSSPVNVTHDESLPLGTIESNSTKDSKYAVQRQQQQVVDFIENNMQLLSSETLNFRSDIMKTLELPIPKRRDIKGNHLSKLLFAKSPLTINTYCQFYDRRTKRICNQEMIWKDKNSREKHGSRKYQRHLSKVHDVQLTPNNFTEFFDHNSPLFQECYDYQSRLMRDLLVEPDAKFKEKKKKKKGDVNGNHPETGSSLINHQVQQQNVRELQSKIAMNDLIEILIDLNIPFSVLDYQPMRNWLIKYSIISTDTLPDEVYFKTDPGVNELEHNSSNLNNSNSGTPHNHNQNQHTN", "length": 376, "header": "sp|Q05043-1|RSF1_YEAST Isoform 1 of Respiration factor 1 OS=Saccharomyces cerevisiae S288C OX=559292 GN=RSF1 PE=1 SV=1 CANONICAL=Q05043-1" }, "locus": { "chromosome": "XIII", "start_pos": 331920, "end_pos": 330793, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "YMR030W_mRNA", "url": "https://www.ensembl.org/id/YMR030W_mRNA" }, { "database": "Ensembl Peptide", "id": "YMR030W", "url": "https://www.ensembl.org/id/YMR030W" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 40, "end_pos": 40, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "Q05043", "url": "https://www.yeastgenome.org/locus/Q05043" }, { "database": "iPTMnet", "id": "Q05043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05043" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Thr40" }, { "start_pos": 73, "end_pos": 73, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q05043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05043" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "Q05043", "url": "https://www.yeastgenome.org/locus/Q05043" } ], "site_lbl": "Ser73" }, { "start_pos": 86, "end_pos": 86, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q05043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05043" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "Q05043", "url": "https://www.yeastgenome.org/locus/Q05043" } ], "site_lbl": "Ser86" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Rsf1p, a protein required for respiratory growth of Saccharomyces cerevisiae.", "journal": "Curr. Genet.", "date": "2003", "authors": "Yu J., Lu L., Simon K., Hudson A.P., Roberts G.", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" } ], "reference": [ { "type": "PubMed", "id": "12734673", "url": "https://glygen.org/publication/PubMed/12734673" } ] }, { "title": "Global analysis of protein localization in budding yeast.", "journal": "Nature", "date": "2003", "authors": "Weissman J.S., Carroll A.S., Howson R.W., Huh W.-K., O'Shea E.K., Falvo J.V., Gerke L.C.", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" } ], "reference": [ { "type": "PubMed", "id": "14562095", "url": "https://glygen.org/publication/PubMed/14562095" } ] }, { "title": "Transcriptional activators in yeast.", "journal": "Nucleic Acids Res.", "date": "2006", "authors": "Chiba T., Ito T., Thomas S., Uetz P., Titz B., Rajagopala S.V.", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" } ], "reference": [ { "type": "PubMed", "id": "16464826", "url": "https://glygen.org/publication/PubMed/16464826" } ] }, { "title": "Genomic analysis of the hierarchical structure of regulatory networks.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2006", "authors": "Yu H., Gerstein M.", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" } ], "reference": [ { "type": "PubMed", "id": "17003135", "url": "https://glygen.org/publication/PubMed/17003135" } ] }, { "title": "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.", "journal": "Genome Res.", "date": "2007", "authors": "Hu Y., LaBaer J., Moreira D., Raphael J., Rolfs A., Zuo D., Richardson A., Simpson A.J.G., Zhu C., Harlow E., Camargo A.A., Jepson D., Kelley F., McCarron S., Taycher E., Kolodner R.D., Kane M.F., Williamson J., Berger M.F., Bulyk M.L., Bhullar B., Mohr S., Marsischky G., Murthy T.V.S.", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" } ], "reference": [ { "type": "PubMed", "id": "17322287", "url": "https://glygen.org/publication/PubMed/17322287" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" }, { "database": "iPTMnet", "id": "Q05043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05043" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science", "date": "2009", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "Q05043", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05043" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.", "journal": "Nature", "date": "1997", "authors": "Connor R., Gentles S., Pearson D., Bowman S., Hunt S., Barrell B.G., Skelton J., Brown D., Rice P., Odell C., Whitehead S., Badcock K., Chillingworth T., Churcher C.M., Dedman K., Devlin K., Hamlin N., Jagels K., Lye G., Moule S., Rajandream M.A., Walsh S.V.", "evidence": [ { "database": "UniProtKB", "id": "Q05043", "url": "https://www.uniprot.org/uniprot/Q05043" } ], "reference": [ { "type": "PubMed", "id": "9169872", "url": "https://glygen.org/publication/PubMed/9169872" } ] } ], "pathway": [ { "id": "sce:YMR030W", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YMR030W", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": 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