{ "uniprot_canonical_ac": "Q04003-1", "uniprot_ac": "Q04003", "uniprot_id": "SAS4_YEAST", "mass": { "chemical_mass": 55409.0, "monoisotopic_mass": 55409.0 }, "refseq": { "ac": "NP_010467", "name": "Sas4p", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010467" }, "gene_names": [ { "name": "SAS4", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q04003", "id": "Q04003" }, { "name": "SAS4", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010467", "id": "NP_010467" }, { "name": "YD9395.15C", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q04003", "id": "Q04003" } ], "protein_names": [ { "name": "Something about silencing protein 4", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q04003" }, { "name": "Sas4p", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010467", "id": "NP_010467" } ], "function": [ { "annotation": "Component of the SAS complex, a multiprotein complex that acetylates 'Lys-16' of histone H4 and 'Lys-14' of histone H3. The SAS complex is however unable to acetylate nucleosomal histones. The complex is involved in transcriptional silencing at telomeres and at HML locus. Also involved in rDNA silencing. In the complex, SAS4 is essential for histone acetyltransferase (HAT) activity of the complex.", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003#function" }, { "database": "PubMed", "id": "12626510", "url": "https://glygen.org/publication/PubMed/12626510" }, { "database": "PubMed", "id": "10471696", "url": "https://glygen.org/publication/PubMed/10471696" }, { "database": "PubMed", "id": "10471697", "url": "https://glygen.org/publication/PubMed/10471697" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "common_name": "Yeast" } ], "gene": [ { "name": "SAS4", "url": "https://www.uniprot.org/uniprot/Q04003", "locus": {} } ], "crossref": [ { "id": "851762", "url": "https://www.ncbi.nlm.nih.gov/gene/851762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q04003", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q04003*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR016158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YDR181C", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YDR181C", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYHKKML", "url": "https://omabrowser.org/oma/group/PYHKKML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2025323at2759", "url": "http://www.orthodb.org/?query=2025323at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38422:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38422:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15460", "url": "http://pfam.xfam.org/family/PF15460", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q04003", "url": "http://purl.obolibrary.org/obo/PR_Q04003", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_010467", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010467", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000002589", "url": "https://www.yeastgenome.org/locus/S000002589", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q04003-1", "url": "https://www.uniprot.org/uniprot/Q04003-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGIFQSIEEANNTSERLLRSEIKNSHGEFEKFDFDTEEYEINPKRKLRLVSRINPNAGHLRKSKSCFTVDEHVDETRCQKPVMKSPFMSNVDDEIKKKRETITKMTLEIEHHELSQNIRKPTDDLLPDSTYQPYHKKMLKQENRMIQSDIVNGENEADRLSLISDRLGMLNWEVTLQKVTKINDPTDENEMETKRYQTKELIDSMLHKFESMKKKSRNLARRPASSDSLLKLVSGKDWPKIYTRIDRTFIPDYASSSDEEEEKITVEEIRERRLKKREQQCGGSIIVLLSDHQSQKGMTRFAIVAEPLRKPYLIKTSTKERNSWKNKVPTNPKKFKKAPRISTQIAVKRRREVIPLTMEVEPEVIRDIRQDTQKSMKLNVKAEEISVTETVKSKEMNALRNNAASISPTLSEKAPLGSISSCTASQISQRSSENVGAIINNINPNLAIVPSCNEKTFVKTHNGMKTNSGINILPVRKKKKV", "length": 481, "header": "sp|Q04003-1|SAS4_YEAST Isoform 1 of Something about silencing protein 4 OS=Saccharomyces cerevisiae S288C OX=559292 GN=SAS4 PE=1 SV=1 CANONICAL=Q04003-1" }, "isoforms": [ { "isoform_ac": "Q04003-1", "url": "", "sequence": { "sequence": "MGIFQSIEEANNTSERLLRSEIKNSHGEFEKFDFDTEEYEINPKRKLRLVSRINPNAGHLRKSKSCFTVDEHVDETRCQKPVMKSPFMSNVDDEIKKKRETITKMTLEIEHHELSQNIRKPTDDLLPDSTYQPYHKKMLKQENRMIQSDIVNGENEADRLSLISDRLGMLNWEVTLQKVTKINDPTDENEMETKRYQTKELIDSMLHKFESMKKKSRNLARRPASSDSLLKLVSGKDWPKIYTRIDRTFIPDYASSSDEEEEKITVEEIRERRLKKREQQCGGSIIVLLSDHQSQKGMTRFAIVAEPLRKPYLIKTSTKERNSWKNKVPTNPKKFKKAPRISTQIAVKRRREVIPLTMEVEPEVIRDIRQDTQKSMKLNVKAEEISVTETVKSKEMNALRNNAASISPTLSEKAPLGSISSCTASQISQRSSENVGAIINNINPNLAIVPSCNEKTFVKTHNGMKTNSGINILPVRKKKKV", "length": 481, "header": "sp|Q04003-1|SAS4_YEAST Isoform 1 of Something about silencing protein 4 OS=Saccharomyces cerevisiae S288C OX=559292 GN=SAS4 PE=1 SV=1 CANONICAL=Q04003-1" }, "locus": { "chromosome": "IV", "start_pos": 827355, "end_pos": 825913, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "YDR181C_mRNA", "url": "https://www.ensembl.org/id/YDR181C_mRNA" }, { "database": "Ensembl Peptide", "id": "YDR181C", "url": "https://www.ensembl.org/id/YDR181C" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 225, "end_pos": 225, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "Q04003", "url": "https://www.yeastgenome.org/locus/Q04003" }, { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser225" }, { "start_pos": 405, "end_pos": 405, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "Q04003", "url": "https://www.yeastgenome.org/locus/Q04003" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser405" }, { "start_pos": 407, "end_pos": 407, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" }, { "database": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" }, { "database": "SGD", "id": "Q04003", "url": "https://www.yeastgenome.org/locus/Q04003" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser407" }, { "start_pos": 411, "end_pos": 411, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ], "site_lbl": "Ser411" }, { "start_pos": 432, "end_pos": 432, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "Q04003", "url": "https://www.yeastgenome.org/locus/Q04003" } ], "site_lbl": "Ser432" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of SAS4 and SAS5, two genes that regulate silencing in Saccharomyces cerevisiae.", "journal": "Genetics", "date": "1999", "authors": "Kim S., Xu E.Y., Rine J., Replogle K., Rivier D.H.", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "10471696", "url": "https://glygen.org/publication/PubMed/10471696" } ] }, { "title": "SAS4 and SAS5 are locus-specific regulators of silencing in Saccharomyces cerevisiae.", "journal": "Genetics", "date": "1999", "authors": "Kim S., Xu E.Y., Rivier D.H.", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "10471697", "url": "https://glygen.org/publication/PubMed/10471697" } ] }, { "title": "Yeast ASF1 protein is required for cell cycle regulation of histone gene transcription.", "journal": "Genetics", "date": "2001", "authors": "Osley M.A., Sternglanz R., Sutton A., Bucaria J.", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "11404324", "url": "https://glygen.org/publication/PubMed/11404324" } ] }, { "title": "The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1.", "journal": "Genes Dev.", "date": "2001", "authors": "Osada S, Sutton A, Muster N, Brown C E, Yates J R, Sternglanz R, Workman J L", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "11731479", "url": "https://glygen.org/publication/PubMed/11731479" } ] }, { "title": "The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.", "journal": "Genes Dev.", "date": "2001", "authors": "Meijsing S H, Ehrenhofer-Murray A E", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "11731480", "url": "https://glygen.org/publication/PubMed/11731480" } ] }, { "title": "Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex.", "journal": "J. Biol. Chem.", "date": "2003", "authors": "Workman J.L., Kaufman P.D., Osada S., Sternglanz R., Sutton A., Band D., Shia W.-J.", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "12626510", "url": "https://glygen.org/publication/PubMed/12626510" } ] }, { "title": "Global analysis of protein expression in yeast.", "journal": "Nature", "date": "2003", "authors": "Dephoure N., Weissman J.S., Howson R.W., Huh W.-K., O'Shea E.K., Belle A., Bower K., Ghaemmaghami S.", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "14562106", "url": "https://glygen.org/publication/PubMed/14562106" } ] }, { "title": "Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.", "journal": "Molecular & cellular proteomics : MCP", "date": "2005-03", "authors": "Gruhler Albrecht, Olsen Jesper V, Mohammed Shabaz, Mortensen Peter, Faergeman Nils J, Mann Matthias, Jensen Ole N", "evidence": [ { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" } ], "reference": [ { "type": "PubMed", "id": "15665377", "url": "https://glygen.org/publication/PubMed/15665377" } ] }, { "title": "Multiple bromodomain genes are involved in restricting the spread of heterochromatic silencing at the Saccharomyces cerevisiae HMR-tRNA boundary.", "journal": "Genetics", "date": "2005", "authors": "Donze D., Agochukwu N.B., Dugas S.L., Ibos M.E., Jambunathan N., Martinez A.W., Robert E.C.", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "16079223", "url": "https://glygen.org/publication/PubMed/16079223" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" }, { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2012", "authors": "Van Damme P, Lasa M, Polevoda B, Gazquez C, Elosegui-Artola A, Kim DS, De Juan-Pardo E, Demeyer K, Hole K, Larrea E, Timmerman E, Prieto J, Arnesen T, Sherman F, Gevaert K, Aldabe R", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "22814378", "url": "https://glygen.org/publication/PubMed/22814378" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "Q04003", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q04003" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.", "journal": "Nature", "date": "1997", "authors": "Andrews S., Bahr A., Bloecker H., Brandt P., Connor R., Du Z., Fulton L., Gentles S., Hawkins J., Hillier L.W., Johnson D., Latreille P., Mardis E., Mewes H.-W., Miller N., Niblett D., Oliver K., Schaefer M., Scharfe M., Vaudin M., Wambutt R., Waterston R., Wedler H., Wilson R., Chen E., Le T., Verhasselt P., Bowman S., Hunt S., Wagner G., Chung E., Nakahara K., Botstein D., Brueckner M., Davis R.W., Lin D., Hankeln T., Schneider C., Schmidt E.R., Duncan M., Favello A., Kucaba T., Rifkin L., Trevaskis E., Wohldman P., Barrell B.G., Rieger M., Berno A., Schroeder M., Ding H., Oh C., Oefner P., Schwarz S., Woelfl S., Kleine K., Becker A., Prydz H., Cooper J., Arnold W., Eide L.G., Kraemer C., Lashkari D., Allen E., Jimenez A., Kuester H., Hoheisel J.D., Pauley A., Paulin L., Brown D., Jaeger W., Volckaert G., Hyman R.W., Andre B., Perez-Alonso M., Araujo R., Komp C., Lew H., Namath A., Roberts D., Paricio N., Boskovic J., Louis E.J., Mulligan J.T., Delaveau T., Greco T., Johnston L., Nhan M., Jones L., Odell C., Menezes S., Johnston M., Pohl T.M., Harris D.E., Schramm S., McDonald S., Salom D., Bargues M., Cherry J.M., Ballesta J.P.G., Churcher C.M., Dedman K., Dietrich F.S., Dujon B., Goffeau A., Hamlin N., Hani J., Jacq C., Mueller-Auer S., Perea J., Perez-Ortin J.E., Rajandream M.A., Remacha M.A., Revuelta J.L., Vissers S., Walsh S.V., Zollner A., del Rey F., Jonniaux J.-L., Purnelle B., Saiz J.E., Urrestarazu L.A., Voet M., Wilcox L., Albermann K., Alt-Moerbe J., Aviles E., Baron L., Biteau N., Blugeon C., Brinkman R., Buitrago M.J., Carpenter J., Coster F., Garcia-Cantalejo J.M., Gattung S., Gomez-Peris A., Granotier C., Hallsworth K., Hanemann V., Heumann K., Hunicke-Smith S., Jier M., Kirsten J., Laamanen P., Langston Y., Legros Y., Moeller-Rieker S., Monnet A., Moro M., Mosedale D., Murphy L.D., Nussbaumer B., Peluso D., Petel F.X., Rasmussen S.W., Richards C., Riles L., Saluz H.P., Saren A.-M., Scholler P., Shogren T., Shore L., Shroff N., Soler-Mira A., Taich A., Vignati D., Wedler E., Winant A., Yelton M.A., Zaccaria P.", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "reference": [ { "type": "PubMed", "id": "9169867", "url": "https://glygen.org/publication/PubMed/9169867" } ] } ], "pathway": [ { "id": "sce:YDR181C", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YDR181C", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "subtelomeric heterochromatin formation", "id": "GO:0031509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031509", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "pmid": "" }, { "name": "histone acetylation", "id": "GO:0016573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016573", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "pmid": "" }, { "name": "SAS acetyltransferase complex", "id": "GO:0033255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033255", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "pmid": "" }, { "name": "acetyltransferase activity", "id": "GO:0016407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016407", "evidence": [ { "database": "UniProtKB", "id": "Q04003", "url": "https://www.uniprot.org/uniprot/Q04003" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }