{
    "uniprot_canonical_ac": "Q02862-1",
    "uniprot_ac": "Q02862",
    "uniprot_id": "CS2LA_MOUSE",
    "mass": {
        "chemical_mass": 21101.0,
        "monoisotopic_mass": 21101.0
    },
    "refseq": {
        "ac": "NP_001291696",
        "name": "alpha-S2-casein-like A isoform 3 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291696"
    },
    "gene_names": [
        {
            "name": "Csn1s2a",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q02862",
            "id": "Q02862"
        },
        {
            "name": "Csn1s2a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291696",
            "id": "NP_001291696"
        },
        {
            "name": "Csng; PP22",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291696",
            "id": "NP_001291696"
        },
        {
            "name": "Csng",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q02862",
            "id": "Q02862"
        }
    ],
    "protein_names": [
        {
            "name": "Alpha-S2-casein-like A",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q02862"
        },
        {
            "name": "Casein alpha S2-like A",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q02862"
        },
        {
            "name": "Gamma-casein",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q02862"
        },
        {
            "name": "PP22",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q02862"
        },
        {
            "name": "alpha-S2-casein-like A isoform 1 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_031811",
            "id": "NP_031811"
        },
        {
            "name": "alpha-S2-casein-like A isoform 2 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291694",
            "id": "NP_001291694"
        },
        {
            "name": "alpha-S2-casein-like A isoform 3 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291696",
            "id": "NP_001291696"
        },
        {
            "name": "alpha-S2-casein-like A isoform 5 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291697",
            "id": "NP_001291697"
        },
        {
            "name": "alpha-S2-casein-like A; gamma casein; milk protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291694",
            "id": "NP_001291694"
        }
    ],
    "function": [
        {
            "annotation": "Important role in the capacity of milk to transport calcium phosphate.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q02862",
                    "url": "https://www.uniprot.org/uniprot/Q02862#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2JGC6",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JGC6#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "ARBA00003383",
                    "url": "https://www.uniprot.org/uniprot/ARBA00003383#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2JET6",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JET6#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q3TP41",
                    "url": "https://www.uniprot.org/uniprot/Q3TP41#function"
                }
            ]
        },
        {
            "annotation": "Promoter is active in lactating mammary tissue; can be induced synergistically by glucocorticoids and prolactin; regulation of the promoter was analysed in cell culture models and compared to the regulaton of the beta casein promoter",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_031811",
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                },
                {
                    "database": "PubMed",
                    "id": "12427545",
                    "url": "https://glygen.org/publication/PubMed/12427545"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001291697",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291697"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001291696",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291696"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001291694",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291694"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q02862",
                    "url": "https://www.uniprot.org/uniprot/Q02862"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Csn1s2a",
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                "end_pos": 87922426,
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                "evidence": [
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                        "database": "Ensembl Gene",
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                        "url": "https://www.ensembl.org/id/ENSMUSG00000061937"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000061937",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000061937",
            "database": "Bgee",
            "categories": [
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            ]
        },
        {
            "id": "12993",
            "url": "https://www.ncbi.nlm.nih.gov/gene/12993",
            "database": "GeneID",
            "categories": [
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            ]
        },
        {
            "id": "IPR011175",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011175",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:12993",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:12993",
            "database": "KEGG Pathway",
            "categories": [
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            ]
        },
        {
            "id": "88542",
            "url": "http://www.informatics.jax.org/marker/MGI:88542",
            "database": "MGI",
            "categories": [
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            ]
        },
        {
            "id": "QRIAMNP",
            "url": "https://omabrowser.org/oma/group/QRIAMNP/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5223369at2759",
            "url": "http://www.orthodb.org/?query=5223369at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR16656",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16656",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR16656:SF7",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16656:SF7",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q02862",
            "url": "http://purl.obolibrary.org/obo/PR_Q02862",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_031811",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_031811",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2JET6",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JET6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2JET6-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JET6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2JGC6",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JGC6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2JGC6-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JGC6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q02862",
            "url": "https://www.uniprot.org/uniprot/Q02862",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q02862-1",
            "url": "https://www.uniprot.org/uniprot/Q02862-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q3TP41",
            "url": "https://www.uniprot.org/uniprot/Q3TP41",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q3TP41-1",
            "url": "https://www.uniprot.org/uniprot/Q3TP41-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MKFFIFACLVVVALAKHEIKDKSSSEESSASIYPGKSKLDNSVFFQTTKDSASSSSSEESSEEVSEKIVQSEEQKVNLNQQKKFKQFSQESSFSQCCTPLHQQQQSSVNQWPQPNAIHNTPTQESISTSVEEILKKIIDMIKYIQYQQVTIPQLPQALHPQIPVSYWYPSKDYTFPNAHYTRFY",
        "length": 184,
        "header": "sp|Q02862-1|CS2LA_MOUSE Isoform 1 of Alpha-S2-casein-like A  OS=Mus musculus OX=10090 GN=Csn1s2a PE=1 SV=1 CANONICAL=Q02862-1"
    },
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        {
            "isoform_ac": "A0A0G2JET6-1",
            "url": "",
            "sequence": {
                "sequence": "MKFFIFACLVVVALAKHEIKDKSSSEESSASIYPGKSKLDNSVFFQTTKDSASSSSSEKIVQSEEQKVNLNQQKKFKQFSQESSFSQCCTPLHQQQQSSVNQWPQPNAIHNTPTQESISTSVEEILKKIIDMIKYIQYQQVTIPQLPQALHPQIPVSYWYPSKDYTFPNAHYTRFY",
                "length": 176,
                "header": "tr|A0A0G2JET6-1|CS2LA_MOUSE Computationally mapped isoform of Alpha-S2-casein-like A  OS=Mus musculus OX=10090 GN=Csn1s2a PE=1 SV=1 CANONICAL=Q02862-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 87935596,
                "end_pos": 87923646,
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                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000200322.5",
                        "url": "https://www.ensembl.org/id/ENSMUST00000200322.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000142901.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000142901.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A0G2JGC6-1",
            "url": "",
            "sequence": {
                "sequence": "MKFFIFACLVVVALAKHEIKDKSSSEESSASIYPGKSKLDNSVFFQTTKDSASSSSSEESSEEVSEKKFKQFSQESSFSQCCTPLHQQQQSSVNQWPQPNAIHNTPTQESISTSVEEILKKIIDMIKYIQYQQVTIPQLPQALHPQIPVSYWYPSKDYTFPNAHYTRFY",
                "length": 169,
                "header": "tr|A0A0G2JGC6-1|A0A0G2JGC6_MOUSE Computationally mapped isoform of Casein alpha s2-like A  OS=Mus musculus OX=10090 GN=Csn1s2a PE=1 SV=1 CANONICAL=Q02862-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 87935596,
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                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000196585.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000196585.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000143515.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000143515.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q02862-1",
            "url": "",
            "sequence": {
                "sequence": "MKFFIFACLVVVALAKHEIKDKSSSEESSASIYPGKSKLDNSVFFQTTKDSASSSSSEESSEEVSEKIVQSEEQKVNLNQQKKFKQFSQESSFSQCCTPLHQQQQSSVNQWPQPNAIHNTPTQESISTSVEEILKKIIDMIKYIQYQQVTIPQLPQALHPQIPVSYWYPSKDYTFPNAHYTRFY",
                "length": 184,
                "header": "sp|Q02862-1|CS2LA_MOUSE Isoform 1 of Alpha-S2-casein-like A  OS=Mus musculus OX=10090 GN=Csn1s2a PE=1 SV=1 CANONICAL=Q02862-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 87935596,
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                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000076379",
                        "url": "https://www.ensembl.org/id/ENSMUST00000076379"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000075716",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000075716"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q3TP41-1",
            "url": "",
            "sequence": {
                "sequence": "MKFFIFACLVVVALAKHEIKDKSSSEESSASIYPGSKLDNSVFFQTTKDSASSSSSEESSEEVSEKIVQSEEQKVNLNQQKKFKQFSQESSFSQCCTPLHQQQQSSVNQWPQPNAIHNTPTQESISTSVEEILKKIIDMIKYIQYQQVTIPQLPQALHPQIPVSYWYPSKDYTFPNAHYTRFY",
                "length": 183,
                "header": "tr|Q3TP41-1|CS2LA_MOUSE Computationally mapped isoform of Alpha-S2-casein-like A  OS=Mus musculus OX=10090 GN=Csn1s2a PE=1 SV=1 CANONICAL=Q02862-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 87935596,
                "end_pos": 87923646,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000196749.5",
                        "url": "https://www.ensembl.org/id/ENSMUST00000196749.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000143715.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000143715.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 23,
            "end_pos": 23,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q02862",
                    "url": "https://www.uniprot.org/uniprot/Q02862"
                },
                {
                    "database": "PubMed",
                    "id": "7763793",
                    "url": "https://glygen.org/publication/PubMed/7763793"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q02862",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02862"
                }
            ],
            "site_lbl": "Ser23"
        },
        {
            "start_pos": 24,
            "end_pos": 24,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q02862",
                    "url": "https://www.uniprot.org/uniprot/Q02862"
                },
                {
                    "database": "PubMed",
                    "id": "7763793",
                    "url": "https://glygen.org/publication/PubMed/7763793"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q02862",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02862"
                }
            ],
            "site_lbl": "Ser24"
        },
        {
            "start_pos": 25,
            "end_pos": 25,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q02862",
                    "url": "https://www.uniprot.org/uniprot/Q02862"
                },
                {
                    "database": "PubMed",
                    "id": "7763793",
                    "url": "https://glygen.org/publication/PubMed/7763793"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q02862",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02862"
                }
            ],
            "site_lbl": "Ser25"
        },
        {
            "start_pos": 37,
            "end_pos": 37,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q02862",
                    "url": "https://www.uniprot.org/uniprot/Q02862"
                },
                {
                    "database": "PubMed",
                    "id": "7763793",
                    "url": "https://glygen.org/publication/PubMed/7763793"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q02862",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02862"
                }
            ],
            "site_lbl": "Ser37"
        }
    ],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Structure and regulation of the murine gamma-casein gene.",
            "journal": "Biochimica et biophysica acta",
            "date": "2002",
            "authors": "Kolb AF",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001291694",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291694"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001291696",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291696"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_031811",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_031811"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001291697",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291697"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12427545",
                    "url": "https://glygen.org/publication/PubMed/12427545"
                }
            ]
        },
        {
            "title": "Mouse gamma-casein cDNA: PCR cloning and sequence analysis.",
            "journal": "Zoological science",
            "date": "1993",
            "authors": "Sasaki T, Sasaki M, Enami J",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q02862",
                    "url": "https://www.uniprot.org/uniprot/Q02862"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q02862",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02862"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "7763793",
                    "url": "https://glygen.org/publication/PubMed/7763793"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:12993",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:12993",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P02667-1",
            "protein_name": "Alpha-S2-casein-like A",
            "gene_name": "Csn1s2a",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MKFFIFTCLVAAALAKHAVKDKPSSEESASVYLGKYKQGNSVFFQTPQDSASSSSSEESSEEISEKIEQSEEQKVNLNQQKKSKQFSQDSSFPQICTPYQQQSSVNQRPQPNAIYDVPSQESTSTSVEEILKKIIDIVKYFQYQQLTNPHFPQAVHPQIRVSSWAPSKDYTFPTARYMA",
                "length": 179
            },
            "evidence": [
                {
                    "id": "45240903",
                    "url": "http://www.informatics.jax.org/homology/45240903",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "extracellular region",
                        "id": "GO:0005576",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q02862",
                                "url": "https://www.uniprot.org/uniprot/Q02862"
                            }
                        ],
                        "pmid": ""
                    },
                    {
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