{ "uniprot_canonical_ac": "Q01815-1", "uniprot_ac": "Q01815", "uniprot_id": "CAC1C_MOUSE", "mass": { "chemical_mass": 240138.0, "monoisotopic_mass": 240138.0 }, "refseq": { "ac": "NP_001153005", "name": "voltage-dependent L-type calcium channel subunit alpha-1C isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005" }, "gene_names": [ { "name": "Cacna1c", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q01815", "id": "Q01815" }, { "name": "CaV1.2-a", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q01815", "id": "Q01815" }, { "name": "Cach2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q01815", "id": "Q01815" }, { "name": "Cacn2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q01815", "id": "Q01815" }, { "name": "Cacna1c", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927", "id": "NP_001242927" }, { "name": "Cacnl1a1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q01815", "id": "Q01815" }, { "name": "Cav1.2; Cchl1a1; D930026N18Rik; MBC; MELC-CC", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927", "id": "NP_001242927" }, { "name": "Cchl1a1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q01815", "id": "Q01815" } ], "protein_names": [ { "name": "Voltage-dependent L-type calcium channel subunit alpha-1C", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q01815" }, { "name": "Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q01815" }, { "name": "MBC", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q01815" }, { "name": "MELC-CC", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q01815" }, { "name": "Mouse brain class C", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q01815" }, { "name": "Voltage-gated calcium channel subunit alpha Cav1.2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q01815" }, { "name": "voltage-dependent L-type calcium channel subunit alpha-1C isoform 10", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242931", "id": "NP_001242931" }, { "name": "voltage-dependent L-type calcium channel subunit alpha-1C isoform 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005", "id": "NP_001153005" }, { "name": "voltage-dependent L-type calcium channel subunit alpha-1C isoform 3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153006", "id": "NP_001153006" }, { "name": "voltage-dependent L-type calcium channel subunit alpha-1C isoform 6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927", "id": "NP_001242927" }, { "name": "voltage-dependent L-type calcium channel subunit alpha-1C isoform 7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242928", "id": "NP_001242928" }, { "name": "voltage-dependent L-type calcium channel subunit alpha-1C isoform 8", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242929", "id": "NP_001242929" }, { "name": "voltage-dependent L-type calcium channel subunit alpha-1C; skeletal muscle-specific calcium channel; calcium channel voltage-dependent alpha1c subunit; neuronal voltage-gated calcium channel alpha 1C subunit; brain class C; voltage-gated calcium channel subunit alpha Cav1.2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242929", "id": "NP_001242929" } ], "function": [ { "annotation": "Increased Ca[2+] signaling through CaV 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties.", "evidence": [ { "database": "RefSeq", "id": "NP_001242927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927" }, { "database": "PubMed", "id": "37261735", "url": "https://glygen.org/publication/PubMed/37261735" }, { "database": "RefSeq", "id": "NP_001242929", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242929" }, { "database": "RefSeq", "id": "NP_001242928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242928" }, { "database": "RefSeq", "id": "NP_001242931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242931" }, { "database": "RefSeq", "id": "NP_001153005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005" }, { "database": "RefSeq", "id": "NP_001153006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153006" } ] }, { "annotation": "Neuronal deletion of CaV1.2 is associated with sex-specific behavioral phenotypes in mice. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001242927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927" }, { "database": "PubMed", "id": "36550186", "url": "https://glygen.org/publication/PubMed/36550186" }, { "database": "RefSeq", "id": "NP_001242929", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242929" }, { "database": "RefSeq", "id": "NP_001242928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242928" }, { "database": "RefSeq", "id": "NP_001242931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242931" }, { "database": "RefSeq", "id": "NP_001153005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005" }, { "database": "RefSeq", "id": "NP_001153006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153006" } ] }, { "annotation": "Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:14609949, PubMed:18586882, PubMed:21216955, PubMed:25368181, PubMed:28119464). Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm (By similarity). Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm (PubMed:21216955). Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells (PubMed:14609949, PubMed:28119464). Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group (Probable).", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815#function" }, { "database": "PubMed", "id": "18586882", "url": "https://glygen.org/publication/PubMed/18586882" }, { "database": "UniProtKB", "id": "P15381", "url": "https://www.uniprot.org/uniprot/P15381#function" }, { "database": "PubMed", "id": "28119464", "url": "https://glygen.org/publication/PubMed/28119464" }, { "database": "PubMed", "id": "14609949", "url": "https://glygen.org/publication/PubMed/14609949" }, { "database": "PubMed", "id": "21216955", "url": "https://glygen.org/publication/PubMed/21216955" }, { "database": "PubMed", "id": "25368181", "url": "https://glygen.org/publication/PubMed/25368181" } ] }, { "annotation": "Silencing of circCacna1c Inhibits ISO-Induced Cardiac Hypertrophy through miR-29b-2-5p/NFATc1 Axis. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001242927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927" }, { "database": "PubMed", "id": "37371137", "url": "https://glygen.org/publication/PubMed/37371137" }, { "database": "RefSeq", "id": "NP_001242929", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242929" }, { "database": "RefSeq", "id": "NP_001242928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242928" }, { "database": "RefSeq", "id": "NP_001242931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242931" }, { "database": "RefSeq", "id": "NP_001153005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005" }, { "database": "RefSeq", "id": "NP_001153006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153006" } ] }, { "annotation": "The CaV1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca(2+) channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome.", "evidence": [ { "database": "RefSeq", "id": "NP_001242927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927" }, { "database": "PubMed", "id": "36162529", "url": "https://glygen.org/publication/PubMed/36162529" }, { "database": "RefSeq", "id": "NP_001242929", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242929" }, { "database": "RefSeq", "id": "NP_001242928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242928" }, { "database": "RefSeq", "id": "NP_001242931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242931" }, { "database": "RefSeq", "id": "NP_001153005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005" }, { "database": "RefSeq", "id": "NP_001153006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153006" } ] }, { "annotation": "Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.", "evidence": [ { "database": "UniProtKB", "id": "A0A087WQT9", "url": "https://www.uniprot.org/uniprot/A0A087WQT9#function" }, { "database": "UniProtKB", "id": "RU003808", "url": "https://www.uniprot.org/uniprot/RU003808#function" }, { "database": "UniProtKB", "id": "A0A1W2P6T3", "url": "https://www.uniprot.org/uniprot/A0A1W2P6T3#function" }, { "database": "UniProtKB", "id": "A0A087WPP1", "url": "https://www.uniprot.org/uniprot/A0A087WPP1#function" }, { "database": "UniProtKB", "id": "A0A087WRZ6", "url": "https://www.uniprot.org/uniprot/A0A087WRZ6#function" }, { "database": "UniProtKB", "id": "F7C376", "url": "https://www.uniprot.org/uniprot/F7C376#function" }, { "database": "UniProtKB", "id": "A0A087WPZ8", "url": "https://www.uniprot.org/uniprot/A0A087WPZ8#function" }, { "database": "UniProtKB", "id": "C7TQ59", "url": "https://www.uniprot.org/uniprot/C7TQ59#function" }, { "database": "UniProtKB", "id": "C7TQ57", "url": "https://www.uniprot.org/uniprot/C7TQ57#function" }, { "database": "UniProtKB", "id": "A0A087WRM3", "url": "https://www.uniprot.org/uniprot/A0A087WRM3#function" }, { "database": "UniProtKB", "id": "A0A1W2P731", "url": "https://www.uniprot.org/uniprot/A0A1W2P731#function" }, { "database": "UniProtKB", "id": "A0A1W2P805", "url": "https://www.uniprot.org/uniprot/A0A1W2P805#function" }, { "database": "UniProtKB", "id": "F8WJL1", "url": "https://www.uniprot.org/uniprot/F8WJL1#function" }, { "database": "UniProtKB", "id": "Q0PCR6", "url": "https://www.uniprot.org/uniprot/Q0PCR6#function" }, { "database": "UniProtKB", "id": "A0A087WR02", "url": "https://www.uniprot.org/uniprot/A0A087WR02#function" }, { "database": "UniProtKB", "id": "A0A087WQJ4", "url": "https://www.uniprot.org/uniprot/A0A087WQJ4#function" }, { "database": "UniProtKB", "id": "A0A1W2P6Z7", "url": "https://www.uniprot.org/uniprot/A0A1W2P6Z7#function" }, { "database": "UniProtKB", "id": "A0A087WSE7", "url": "https://www.uniprot.org/uniprot/A0A087WSE7#function" }, { "database": "UniProtKB", "id": "A0A087WS67", "url": "https://www.uniprot.org/uniprot/A0A087WS67#function" }, { "database": "UniProtKB", "id": "A0A087WS40", "url": "https://www.uniprot.org/uniprot/A0A087WS40#function" } ] } ], "disease": [ { "disease_id": "DOID:0050741", "recommended_name": { "id": "DOID:0050741", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol." }, "synonyms": [ { "id": "DOID:0050741", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050741", "name": "alcoholism", "description": "" }, { "id": "MONDO:0007079", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007079", "name": "alcohol dependence", "description": "Physical and psychological dependence on alcohol." }, { "id": "MONDO:0007079", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007079", "name": "alcohol dependence", "description": "" }, { "id": "MONDO:0007079", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007079", "name": "alcoholism", "description": "" }, { "id": "MONDO:0007079", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007079", "name": "aerodigestive tract cancer, squamous cell, alcohol-related, protection against", "description": "" }, { "id": "MONDO:0007079", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007079", "name": "alcohol dependence, protection against", "description": "" }, { "id": "MONDO:0007079", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007079", "name": "alcohol dependence, susceptibility to", "description": "" } ], "evidence": [ { "id": "0050741", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ] }, { "disease_id": "DOID:0060173", "recommended_name": { "id": "DOID:0060173", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060173", "name": "Timothy syndrome", "description": "A syndrome that is characterized by cardiac, hand/foot, facial, and neurodevelopmental features. The two forms are type 1 (classic) and type 2, a rare form that has_material_basis_in mutations in a transcript variant of the CACNA1C gene on chromosome 12p13.33." }, "synonyms": [ { "id": "MONDO:0010979", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010979", "name": "Timothy syndrome", "description": "Timothy syndrome is a multi-system disorder characterized by cardiac, hand, facial and neurodevelopmental features that include QT prolongation, webbed fingers and toes, flattened nasal bridge, low-set ears, small upper jaw, thin upper lip, and characteristic features of autism or autistic spectrum disorders." }, { "id": "MONDO:0010979", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010979", "name": "TIMOTHY syndrome", "description": "" }, { "id": "MONDO:0010979", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010979", "name": "TS", "description": "" }, { "id": "MONDO:0010979", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010979", "name": "Timothy syndrome", "description": "" }, { "id": "MONDO:0010979", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010979", "name": "long QT syndrome-syndactyly syndrome", "description": "" }, { "id": "MONDO:0010979", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010979", "name": "LQT8", "description": "" }, { "id": "MONDO:0010979", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010979", "name": "long QT syndrome 8", "description": "" }, { "id": "MONDO:0010979", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010979", "name": "long QT syndrome type 8", "description": "" }, { "id": "MONDO:0010979", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010979", "name": "long QT syndrome with syndactyly", "description": "" }, { "id": "MIM:601005", "resource": "MIM", "url": "https://www.omim.org/entry/601005", "name": "Timothy syndrome", "description": "Timothy syndrome" } ], "evidence": [ { "id": "0060173", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0060173" } ] }, { "disease_id": "DOID:0110220", "recommended_name": { "id": "DOID:0110220", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110220", "name": "Brugada syndrome 3", "description": "A Brugada syndrome that has_material_basis_in heterozygous mutation in the gene encoding the alpha-1C subunit of the L-type voltage-dependent calcium channel (CACNA1C) on chromosome 12p13." }, "synonyms": [ { "id": "DOID:0110220", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110220", "name": "BRGDA3", "description": "" }, { "id": "MONDO:0012742", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012742", "name": "Brugada syndrome 3", "description": "Any Brugada syndrome in which the cause of the disease is a mutation in the CACNA1C gene." }, { "id": "MONDO:0012742", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012742", "name": "BRGDA3", "description": "" }, { "id": "MONDO:0012742", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012742", "name": "Brugada syndrome 3", "description": "" }, { "id": "MONDO:0012742", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012742", "name": "Brugada syndrome caused by mutation in CACNA1C", "description": "" }, { "id": "MONDO:0012742", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012742", "name": "Brugada syndrome type 3", "description": "" }, { "id": "MONDO:0012742", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012742", "name": "CACNA1C Brugada syndrome", "description": "" }, { "id": "MIM:611875", "resource": "MIM", "url": "https://www.omim.org/entry/611875", "name": "Brugada syndrome 3", "description": "Brugada syndrome 3" } ], "evidence": [ { "id": "0110220", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0110220" } ] }, { "disease_id": "DOID:11723", "recommended_name": { "id": "DOID:11723", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11723", "name": "Duchenne muscular dystrophy", "description": "A muscular dystrophy that has_material_basis_in X-linked mutations in the DMD gene found on the X chromosome. It is characterized by rapidly progressing muscle weakness and muscle atrophy initially involving the lower extremities and eventually affecting the whole body. It affects males whereas females can be carriers. The symptoms start before the age of six and may appear at infancy." }, "synonyms": [ { "id": "DOID:11723", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11723", "name": "Muscular dystrophy, Duchenne", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "Duchenne muscular dystrophy", "description": "Duchenne muscular dystrophy (DMD) is a neuromuscular disease characterized by rapidly progressive muscle weakness and wasting due to degeneration of skeletal, smooth and cardiac muscle." }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "DMD", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "Duchenne muscular dystrophy", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "Duchenne muscular dystrophy, X-linked recessive", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "muscular dystrophy, Duchenne", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "severe dystrophinopathy, Duchenne type", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "muscular dystrophy, Duchenne type", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "muscular dystrophy, pseudohypertrophic progressive, Duchenne type", "description": "" }, { "id": "MIM:310200", "resource": "MIM", "url": "https://www.omim.org/entry/310200", "name": "Duchenne muscular dystrophy", "description": "Duchenne muscular dystrophy" } ], "evidence": [ { "id": "11723", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:11723" } ] } ], "snv": [ { "evidence": [ { "id": "rs3397432642", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397432642" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "start_pos": 153, "end_pos": 153, "sequence_org": "N", "sequence_mut": "K", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NAT->KAT).", "chr_id": "6", "chr_pos": "119029580", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N153", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs31579954", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs31579954" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 1740, "end_pos": 1740, "sequence_org": "T", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (TES->NES).", "chr_id": "6", "chr_pos": "118579228", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T1740", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs3388849357", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388849357" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 2015, "end_pos": 2015, "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (SLT->NLT).", "chr_id": "6", "chr_pos": "118573055", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S2015", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [ { "start_pos": 1670, "end_pos": 1670, "sequence_org": "S", "sequence_mut": "A", "comment": "Expected to abolish a phosphorylation site. Decreased channel activity. No effect on phosphorylation at S-1897. Causes heart hypertrophy and decreased exercise tolerance in adult mice.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "25368181", "url": "https://glygen.org/publication/PubMed/25368181" } ] }, { "start_pos": 1794, "end_pos": 1796, "sequence_org": "HGP", "sequence_mut": "LSK", "comment": "Strongly decreased channel activity due to decreased expression at the cell membrane, leading to hypertrophy of the right heart ventricle, heart failure and perinatal death; when associated with 1797-P--L-2139 DEL.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "21216955", "url": "https://glygen.org/publication/PubMed/21216955" } ] }, { "start_pos": 1797, "end_pos": 2139, "sequence_org": "PLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "sequence_mut": "", "comment": "Strongly decreased channel activity due to decreased expression at the cell membrane, leading to hypertrophy of the right heart ventricle, heart failure and perinatal death; when associated with 1794-L--K-1796.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "21216955", "url": "https://glygen.org/publication/PubMed/21216955" } ] }, { "start_pos": 1897, "end_pos": 1897, "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of phosphorylation site. Abolishes increased vasoconstriction in response to elevated blood glucose.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "28119464", "url": "https://glygen.org/publication/PubMed/28119464" } ] } ], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Cacna1c", "url": "https://www.uniprot.org/uniprot/Q01815", "locus": { "chromosome": "6", "start_pos": 118564201, "end_pos": 119173851, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000051331", "url": "https://www.ensembl.org/id/ENSMUSG00000051331" } ] } } ], "crossref": [ { "id": "ENSMUSG00000051331", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000051331", "database": "Bgee", "categories": [ "Gene 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Classification" ] }, { "id": "IPR014873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:12288", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:12288", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "103013", "url": "http://www.informatics.jax.org/marker/MGI:103013", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "Q01815", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q01815", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "DCCGDEN", "url": "https://omabrowser.org/oma/group/DCCGDEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "1110761at2759", "url": "http://www.orthodb.org/?query=1110761at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45628:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45628:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "http://pfam.xfam.org/family/PF00520", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF08763", "url": "http://pfam.xfam.org/family/PF08763", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF16885", "url": "http://pfam.xfam.org/family/PF16885", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF16905", "url": "http://pfam.xfam.org/family/PF16905", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q01815", "url": "http://purl.obolibrary.org/obo/PR_Q01815", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-MMU-422356", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-422356", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-5576892", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5576892", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-5576893", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5576893", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001153005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A087WPP1", "url": "https://www.uniprot.org/uniprot/A0A087WPP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WPP1-1", "url": "https://www.uniprot.org/uniprot/A0A087WPP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WPZ8", "url": "https://www.uniprot.org/uniprot/A0A087WPZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WPZ8-1", "url": "https://www.uniprot.org/uniprot/A0A087WPZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WQJ4", "url": "https://www.uniprot.org/uniprot/A0A087WQJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WQJ4-1", "url": "https://www.uniprot.org/uniprot/A0A087WQJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WQT9", "url": "https://www.uniprot.org/uniprot/A0A087WQT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WQT9-1", "url": "https://www.uniprot.org/uniprot/A0A087WQT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WR02", "url": "https://www.uniprot.org/uniprot/A0A087WR02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WR02-1", "url": "https://www.uniprot.org/uniprot/A0A087WR02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WRM3", "url": "https://www.uniprot.org/uniprot/A0A087WRM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WRM3-1", "url": "https://www.uniprot.org/uniprot/A0A087WRM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WRZ6", "url": "https://www.uniprot.org/uniprot/A0A087WRZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WRZ6-1", "url": "https://www.uniprot.org/uniprot/A0A087WRZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WS40", "url": "https://www.uniprot.org/uniprot/A0A087WS40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WS40-1", "url": "https://www.uniprot.org/uniprot/A0A087WS40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WS67", "url": "https://www.uniprot.org/uniprot/A0A087WS67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WS67-1", "url": "https://www.uniprot.org/uniprot/A0A087WS67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WSE7", "url": "https://www.uniprot.org/uniprot/A0A087WSE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WSE7-1", "url": "https://www.uniprot.org/uniprot/A0A087WSE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2P6T3", "url": "https://www.uniprot.org/uniprot/A0A1W2P6T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2P6T3-1", "url": "https://www.uniprot.org/uniprot/A0A1W2P6T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2P6Z7", "url": "https://www.uniprot.org/uniprot/A0A1W2P6Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2P6Z7-1", "url": "https://www.uniprot.org/uniprot/A0A1W2P6Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2P731", "url": "https://www.uniprot.org/uniprot/A0A1W2P731", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2P731-1", "url": "https://www.uniprot.org/uniprot/A0A1W2P731-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2P805", "url": "https://www.uniprot.org/uniprot/A0A1W2P805", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2P805-1", "url": "https://www.uniprot.org/uniprot/A0A1W2P805-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A668KLV2", "url": "https://www.uniprot.org/uniprot/A0A668KLV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A668KLV2-1", "url": "https://www.uniprot.org/uniprot/A0A668KLV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "C7TQ57", "url": "https://www.uniprot.org/uniprot/C7TQ57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "C7TQ57-1", "url": "https://www.uniprot.org/uniprot/C7TQ57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "C7TQ59", "url": "https://www.uniprot.org/uniprot/C7TQ59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "C7TQ59-1", "url": "https://www.uniprot.org/uniprot/C7TQ59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F7C376", "url": "https://www.uniprot.org/uniprot/F7C376", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F7C376-1", "url": "https://www.uniprot.org/uniprot/F7C376-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F8WJL1", "url": "https://www.uniprot.org/uniprot/F8WJL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F8WJL1-1", "url": "https://www.uniprot.org/uniprot/F8WJL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q01815-1", "url": "https://www.uniprot.org/uniprot/Q01815-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q01815-2", "url": "https://www.uniprot.org/uniprot/Q01815-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q01815-3", "url": "https://www.uniprot.org/uniprot/Q01815-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0PCR6", "url": "https://www.uniprot.org/uniprot/Q0PCR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0PCR6-1", "url": "https://www.uniprot.org/uniprot/Q0PCR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2139, "header": "sp|Q01815-1|CAC1C_MOUSE Isoform 1 of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "isoforms": [ { "isoform_ac": "A0A087WPP1-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2167, "header": "tr|A0A087WPP1-1|A0A087WPP1_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000189389.7", "url": "https://www.ensembl.org/id/ENSMUST00000189389.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000139855.2", "url": "https://www.ensembl.org/id/ENSMUSP00000139855.2" } ] } }, { "isoform_ac": "A0A087WPZ8-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2139, "header": "tr|A0A087WPZ8-1|A0A087WPZ8_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000188865.7", "url": "https://www.ensembl.org/id/ENSMUST00000188865.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000139981.2", "url": "https://www.ensembl.org/id/ENSMUSP00000139981.2" } ] } }, { "isoform_ac": "A0A087WQJ4-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVHSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2156, "header": "tr|A0A087WQJ4-1|A0A087WQJ4_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000189520.7", "url": "https://www.ensembl.org/id/ENSMUST00000189520.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140220.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140220.2" } ] } }, { "isoform_ac": "A0A087WQT9-1", "url": "", "sequence": { "sequence": "MNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2135, "header": "tr|A0A087WQT9-1|A0A087WQT9_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119034438, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000187386.7", "url": "https://www.ensembl.org/id/ENSMUST00000187386.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140341.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140341.2" } ] } }, { "isoform_ac": "A0A087WR02-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2139, "header": "tr|A0A087WR02-1|A0A087WR02_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000188078.7", "url": "https://www.ensembl.org/id/ENSMUST00000188078.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140415.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140415.2" } ] } }, { "isoform_ac": "A0A087WRM3-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2187, "header": "tr|A0A087WRM3-1|A0A087WRM3_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000187317.7", "url": "https://www.ensembl.org/id/ENSMUST00000187317.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140693.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140693.2" } ] } }, { "isoform_ac": "A0A087WRZ6-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2159, "header": "tr|A0A087WRZ6-1|A0A087WRZ6_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000185345.7", "url": "https://www.ensembl.org/id/ENSMUST00000185345.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140833.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140833.2" } ] } }, { "isoform_ac": "A0A087WS40-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2153, "header": "tr|A0A087WS40-1|A0A087WS40_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000188106.7", "url": "https://www.ensembl.org/id/ENSMUST00000188106.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140886.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140886.2" } ] } }, { "isoform_ac": "A0A087WS67-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2164, "header": "tr|A0A087WS67-1|A0A087WS67_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000188522.7", "url": "https://www.ensembl.org/id/ENSMUST00000188522.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140920.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140920.2" } ] } }, { "isoform_ac": "A0A087WSE7-1", "url": "", "sequence": { "sequence": "MIRAFVQPSTPPYQPLSSHSSEETERKFKGKVVHEAQLNCFYISPGGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2194, "header": "tr|A0A087WSE7-1|CAC1C_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119173192, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000190285.2", "url": "https://www.ensembl.org/id/ENSMUST00000190285.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000141015.2", "url": "https://www.ensembl.org/id/ENSMUSP00000141015.2" } ] } }, { "isoform_ac": "A0A1W2P6T3-1", "url": "", "sequence": { "sequence": "ERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 1969, "header": "tr|A0A1W2P6T3-1|CAC1C_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 118757285, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000219223.2", "url": "https://www.ensembl.org/id/ENSMUST00000219223.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000151391.2", "url": "https://www.ensembl.org/id/ENSMUSP00000151391.2" } ] } }, { "isoform_ac": "A0A1W2P6Z7-1", "url": "", "sequence": { "sequence": "ERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2005, "header": "tr|A0A1W2P6Z7-1|CAC1C_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 118757285, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000219833.2", "url": "https://www.ensembl.org/id/ENSMUST00000219833.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000151462.2", "url": "https://www.ensembl.org/id/ENSMUSP00000151462.2" } ] } }, { "isoform_ac": "A0A1W2P731-1", "url": "", "sequence": { "sequence": "ERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMVRTTLQTTFPASVAPPLATHVLSTLISRALGTQPSSHCMWPPCPLCALTACAHVSCARSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2063, "header": "tr|A0A1W2P731-1|CAC1C_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 118757285, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000220022.2", "url": "https://www.ensembl.org/id/ENSMUST00000220022.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000151458.2", "url": "https://www.ensembl.org/id/ENSMUSP00000151458.2" } ] } }, { "isoform_ac": "A0A1W2P805-1", "url": "", "sequence": { "sequence": "ERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 1980, "header": "tr|A0A1W2P805-1|A0A1W2P805_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 118757285, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000219018.2", "url": "https://www.ensembl.org/id/ENSMUST00000219018.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000151863.2", "url": "https://www.ensembl.org/id/ENSMUSP00000151863.2" } ] } }, { "isoform_ac": "A0A668KLV2-1", "url": "", "sequence": { "sequence": "MIRAFVQPSTPPYQPLSSHSSEETERKFKGKVVHEAQLNCFYISPGGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLSPEVSLRRGPLWPSASDTMRTLQCLGILLFFWFEFWWITTSESCCVNVSIFWFICLLVVWGIWQIQ", "length": 255, "header": "tr|A0A668KLV2-1|A0A668KLV2_MOUSE Computationally mapped isoform of Calcium channel, voltage-dependent, L type, alpha 1C subunit OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119173192, "end_pos": 118932536, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000239204.2", "url": "https://www.ensembl.org/id/ENSMUST00000239204.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000159252.2", "url": "https://www.ensembl.org/id/ENSMUSP00000159252.2" } ] } }, { "isoform_ac": "C7TQ57-1", "url": "", "sequence": { "sequence": "MIRAFVQPSTPPYQPLSSHSSEETERKFKGKVVHEAQLNCFYISPGGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2169, "header": "tr|C7TQ57-1|CAC1C_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119173192, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000187940.7", "url": "https://www.ensembl.org/id/ENSMUST00000187940.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000141033.2", "url": "https://www.ensembl.org/id/ENSMUSP00000141033.2" } ] } }, { "isoform_ac": "C7TQ59-1", "url": "", "sequence": { "sequence": "MIRAFVQPSTPPYQPLSSHSSEETERKFKGKVVHEAQLNCFYISPGGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2169, "header": "tr|C7TQ59-1|C7TQ59_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119173192, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000187474.7", "url": "https://www.ensembl.org/id/ENSMUST00000187474.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140961.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140961.2" } ] } }, { "isoform_ac": "F7C376-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMVRTTLQTTFPASVAPPLATHVLSTLISRALGTQPSSHCMWPPCPLCALTACAHVSCARSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2222, "header": "tr|F7C376-1|CAC1C_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=2 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000112793.10", "url": "https://www.ensembl.org/id/ENSMUST00000112793.10" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000108413.5", "url": "https://www.ensembl.org/id/ENSMUSP00000108413.5" } ] } }, { "isoform_ac": "F8WJL1-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2139, "header": "tr|F8WJL1-1|F8WJL1_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=2 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000112790.9", "url": "https://www.ensembl.org/id/ENSMUST00000112790.9" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000108410.4", "url": "https://www.ensembl.org/id/ENSMUSP00000108410.4" } ] } }, { "isoform_ac": "Q01815-1", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2139, "header": "sp|Q01815-1|CAC1C_MOUSE Isoform 1 of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119084936, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000075591", "url": "https://www.ensembl.org/id/ENSMUST00000075591" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000075021", "url": "https://www.ensembl.org/id/ENSMUSP00000075021" } ] } }, { "isoform_ac": "Q01815-2", "url": "", "sequence": { "sequence": "MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVHSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2128, "header": "sp|Q01815-2|CAC1C_MOUSE Isoform 2 of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": {} }, { "isoform_ac": "Q01815-3", "url": "", "sequence": { "sequence": "MVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 1869, "header": "sp|Q01815-3|CAC1C_MOUSE Isoform 3 of Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 118734452, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000112825", "url": "https://www.ensembl.org/id/ENSMUST00000112825" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000108444", "url": "https://www.ensembl.org/id/ENSMUSP00000108444" } ] } }, { "isoform_ac": "Q0PCR6-1", "url": "", "sequence": { "sequence": "MIRAFVQPSTPPYQPLSSHSSEETERKFKGKVVHEAQLNCFYISPGGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVNQEIFPDETRSVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLTCPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSRGRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRGRSEEALADSRSYVSNL", "length": 2169, "header": "tr|Q0PCR6-1|Q0PCR6_MOUSE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit alpha OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1 CANONICAL=Q01815-1" }, "locus": { "chromosome": "6", "start_pos": 119173192, "end_pos": 118570856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000186889.7", "url": "https://www.ensembl.org/id/ENSMUST00000186889.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140056.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140056.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 1388, "start_aa": "Asn", "end_pos": 1388, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1388", "evidence": [ { "id": "Q01815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01815#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 1439, "start_aa": "Asn", "end_pos": 1439, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1439", "evidence": [ { "id": "Q01815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01815#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 153, "start_aa": "Asn", "end_pos": 153, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn153", "evidence": [ { "id": "Q01815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01815#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 328, "start_aa": "Asn", "end_pos": 328, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn328", "evidence": [ { "id": "F8WJL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F8WJL1#ptm_processing" }, { "id": "PIRSR602077-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-3" }, { "id": "A0A087WS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WS67#ptm_processing" }, { "id": "A0A087WQJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WQJ4#ptm_processing" }, { "id": "A0A087WRM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WRM3#ptm_processing" }, { "id": "A0A087WPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WPP1#ptm_processing" }, { "id": "A0A087WS40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WS40#ptm_processing" }, { "id": "F7C376", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7C376#ptm_processing" }, { "id": "Q01815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01815#ptm_processing" }, { "id": "A0A087WPZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WPZ8#ptm_processing" }, { "id": "A0A087WR02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WR02#ptm_processing" }, { "id": "A0A087WRZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WRZ6#ptm_processing" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "Q01815", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q01815" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "32910282", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32910282" } ] } ], "phosphorylation": [ { "start_pos": 1670, "end_pos": 1670, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "25368181", "url": "https://glygen.org/publication/PubMed/25368181" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "site_lbl": "Ser1670" }, { "start_pos": 1691, "end_pos": 1691, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "site_lbl": "Ser1691" }, { "start_pos": 1897, "end_pos": 1897, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKA", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" }, { "database": "PubMed", "id": "28119464", "url": "https://glygen.org/publication/PubMed/28119464" }, { "database": "PubMed", "id": "25368181", "url": "https://glygen.org/publication/PubMed/25368181" } ], "site_lbl": "Ser1897" }, { "start_pos": 469, "end_pos": 469, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "site_lbl": "Ser469" }, { "start_pos": 476, "end_pos": 476, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "site_lbl": "Thr476" }, { "start_pos": 783, "end_pos": 783, "kinase_uniprot_canonical_ac": "P49615-1", "kinase_gene_name": "Cdk5", "residue": "Ser", "comment": "", "evidence": [ { "database": "phospho.ELM", "id": "Q01815", "url": "http://phospho.elm.eu.org/byAccession/Q01815.html" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" }, { "database": "PubMed", "id": "16155576", "url": "https://glygen.org/publication/PubMed/16155576" } ], "site_lbl": "Ser783" }, { "start_pos": 808, "end_pos": 808, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "site_lbl": "Ser808" }, { "start_pos": 815, "end_pos": 815, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "phospho.ELM", "id": "Q01815", "url": "http://phospho.elm.eu.org/byAccession/Q01815.html" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" }, { "database": "PubMed", "id": "17114649", "url": "https://glygen.org/publication/PubMed/17114649" } ], "site_lbl": "Ser815" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported", "glycoprotein_predicted", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse.", "journal": "J. Biol. Chem.", "date": "2000", "authors": "Feil R., Hofmann F., Klugbauer N., Striessnig J., Pfeifer A., Platzer J., Welling A., Specht V., Kuehbandner S., Seisenberger C.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "reference": [ { "type": "PubMed", "id": "10973973", "url": "https://glygen.org/publication/PubMed/10973973" } ] }, { "title": "Expression of a cDNA for a neuronal calcium channel alpha1 subunit enhances secretion from adrenal chromaffin cells.", "journal": "J. Biol. Chem.", "date": "1992", "authors": "Uhler M.D., Ma W.-J., Holz R.W.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "reference": [ { "type": "PubMed", "id": "1385406", "url": "https://glygen.org/publication/PubMed/1385406" } ] }, { "title": "Dominant role of smooth muscle L-type calcium channel Cav1.2 for blood pressure regulation.", "journal": "EMBO J.", "date": "2003", "authors": "Feil R., Hofmann F., Klugbauer N., Feil S., Welling A., Moosmang S., Schulla V., Wegener J.W.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "reference": [ { "type": "PubMed", "id": "14609949", "url": "https://glygen.org/publication/PubMed/14609949" } ] }, { "title": "Cdk5-dependent regulation of glucose-stimulated insulin secretion.", "journal": "Nature medicine", "date": "2005", "authors": "Wei FY, Nagashima K, Ohshima T, Saheki Y, Lu YF, Matsushita M, Yamada Y, Mikoshiba K, Seino Y, Matsui H, Tomizawa K", "evidence": [ { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "reference": [ { "type": "PubMed", "id": "16155576", "url": "https://glygen.org/publication/PubMed/16155576" } ] }, { "title": "Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.", "journal": "J. Mol. Cell. Cardiol.", "date": "2006", "authors": "Ito H., Takahashi Y., Watanabe H., Murakami M., Ono K., Nakayama S., Miyoshi I., Iijima T., Ohba T.", "evidence": [ { "database": "UniProtKB", "id": "Q0PCR6", "url": "https://www.uniprot.org/uniprot/Q0PCR6" } ], "reference": [ { "type": "PubMed", "id": "16787652", "url": "https://glygen.org/publication/PubMed/16787652" } ] }, { "title": "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.", "journal": "Molecular & cellular proteomics : MCP", "date": "2007", "authors": "Munton RP, Tweedie-Cullen R, Livingstone-Zatchej M, Weinandy F, Waidelich M, Longo D, Gehrig P, Potthast F, Rutishauser D, Gerrits B, Panse C, Schlapbach R, Mansuy IM", "evidence": [ { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "reference": [ { "type": "PubMed", "id": "17114649", "url": "https://glygen.org/publication/PubMed/17114649" } ] }, { "title": "Characterization of Ca2+-binding protein 5 knockout mouse retina.", "journal": "Invest. Ophthalmol. Vis. Sci.", "date": "2008", "authors": "Lee A., Haeseleer F., Rieke F.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "reference": [ { "type": "PubMed", "id": "18586882", "url": "https://glygen.org/publication/PubMed/18586882" } ] }, { "title": "CIB1 is a regulator of pathological cardiac hypertrophy.", "journal": "Nat. Med.", "date": "2010", "authors": "Xu J., Yuan W., Molkentin J.D., Auger-Messier M., Benard M.J., Correll R.N., Drexler H., Heineke J., Parise L.V.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "reference": [ { "type": "PubMed", "id": "20639889", "url": "https://glygen.org/publication/PubMed/20639889" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo.", "journal": "J. Biol. Chem.", "date": "2011", "authors": "Fu Y, Westenbroek RE, Yu FH, Clark JP 3rd, Marshall MR, Scheuer T, Catterall WA", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "reference": [ { "type": "PubMed", "id": "21216955", "url": "https://glygen.org/publication/PubMed/21216955" } ] }, { "title": "Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.", "journal": "J. Biol. Chem.", "date": "1990", "authors": "Perez-Reyes E, Wei XY, Castellano A, Birnbaumer L", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "reference": [ { "type": "PubMed", "id": "2173707", "url": "https://glygen.org/publication/PubMed/2173707" } ] }, { "title": "Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2012", "authors": "Christensen G., Louch W.E., Franzini-Armstrong C., Andersson K.B., Enger U.H., Oeyehaug L., Sejersted O.M., Swift F.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "reference": [ { "type": "PubMed", "id": "22355118", "url": "https://glygen.org/publication/PubMed/22355118" } ] }, { "title": "Basal and beta-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2014", "authors": "Fu Y, Westenbroek RE, Scheuer T, Catterall WA", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" }, { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "reference": [ { "type": "PubMed", "id": "25368181", "url": "https://glygen.org/publication/PubMed/25368181" } ] }, { "title": "Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes.", "journal": "Science signaling", "date": "2017", "authors": "Nystoriak MA, Nieves-Cintron M, Patriarchi T, Buonarati OR, Prada MP, Morotti S, Grandi E, Fernandes JD, Forbush K, Hofmann F, Sasse KC, Scott JD, Ward SM, Hell JW, Navedo MF", "evidence": [ { "database": "iPTMnet", "id": "Q01815", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01815" } ], "reference": [ { "type": "PubMed", "id": "28119464", "url": "https://glygen.org/publication/PubMed/28119464" } ] }, { "title": "Intracellular O-linked glycosylation directly regulates cardiomyocyte L-type Ca(2+) channel activity and excitation-contraction coupling.", "journal": "Basic research in cardiology", "date": "2020", "authors": "Ednie AR, Bennett ES", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q01815", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q01815" } ], "reference": [ { "type": "PubMed", "id": "32910282", "url": "https://glygen.org/publication/PubMed/32910282" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q01815", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q01815" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "The CaV1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca2+ channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome.", "journal": "Neuropharmacology", "date": "2022-12-01", "authors": "Sanderson Jennifer L, Freund Ronald K, Castano Anna M, Benke Timothy A, Dell'Acqua Mark L", "evidence": [ { "database": "RefSeq", "id": "NP_001242927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927" }, { "database": "RefSeq", "id": "NP_001153005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005" }, { "database": "RefSeq", "id": "NP_001242928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242928" }, { "database": "RefSeq", "id": "NP_001242931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242931" }, { "database": "RefSeq", "id": "NP_001153006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153006" }, { "database": "RefSeq", "id": "NP_001242929", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242929" } ], "reference": [ { "type": "PubMed", "id": "36162529", "url": "https://glygen.org/publication/PubMed/36162529" } ] }, { "title": "Neuronal deletion of CaV1.2 is associated with sex-specific behavioral phenotypes in mice.", "journal": "Scientific reports", "date": "2022-12-22", "authors": "Klomp Annette J, Plumb Ashley, Mehr Jacqueline B, Madencioglu Deniz A, Wen Hsiang, Williams Aislinn J", "evidence": [ { "database": "RefSeq", "id": "NP_001242928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242928" }, { "database": "RefSeq", "id": "NP_001242931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242931" }, { "database": "RefSeq", "id": "NP_001242927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927" }, { "database": "RefSeq", "id": "NP_001242929", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242929" }, { "database": "RefSeq", "id": "NP_001153005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005" }, { "database": "RefSeq", "id": "NP_001153006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153006" } ], "reference": [ { "type": "PubMed", "id": "36550186", "url": "https://glygen.org/publication/PubMed/36550186" } ] }, { "title": "Increased Ca2+ signaling through CaV 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2023-07", "authors": "Li Haiyin, Korcari Antonion, Ciufo David, Mendias Christopher L, Rodeo Scott A, Buckley Mark R, Loiselle Alayna E, Pitt Geoffrey S, Cao Chike", "evidence": [ { "database": "RefSeq", "id": "NP_001242927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242927" }, { "database": "RefSeq", "id": "NP_001242929", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242929" }, { "database": "RefSeq", "id": "NP_001242928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001242928" }, { "database": "RefSeq", "id": "NP_001153005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153005" }, { "database": "RefSeq", "id": "NP_001153006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153006" }, { "database": "RefSeq", "id": "NP_001242931", "url": 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Biol. Chem.", "date": "1995", "authors": "Ma Y., Marks A.R., Kobrinsky E.", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "reference": [ { "type": "PubMed", "id": "7814415", "url": "https://glygen.org/publication/PubMed/7814415" } ] } ], "pathway": [ { "id": "mmu:12288", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:12288", "resource": "KEGG Pathway" }, { "id": "R-MMU-422356", "name": "Regulation of insulin secretion", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-422356", "resource": "Reactome", "description": "Regulation of insulin secretion" }, { "id": "R-MMU-5576892", "name": "Phase 0 - rapid depolarisation", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5576892", "resource": "Reactome", "description": "Phase 0 - rapid depolarisation" }, { "id": "R-MMU-5576893", "name": "Phase 2 - plateau phase", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5576893", "resource": 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"length": 2169 }, "evidence": [ { "id": "45223988", "url": "http://www.informatics.jax.org/homology/45223988", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13936-1", "protein_name": "Voltage-dependent L-type calcium channel subunit alpha-1C", "gene_name": "CACNA1C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 2221 }, "evidence": [ { "id": "45223988", "url": "http://www.informatics.jax.org/homology/45223988", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 13, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "alpha-actinin binding", "id": "GO:0051393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051393", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "high voltage-gated calcium channel activity", "id": "GO:0008331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008331", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity involved in AV node cell action potential", "id": "GO:0086056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086056", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "protein phosphatase 2A binding", "id": "GO:0051721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051721", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity involved in cardiac muscle cell action potential", "id": "GO:0086007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086007", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1905030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905030", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 21, "go_terms": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q01815", "url": "https://www.uniprot.org/uniprot/Q01815" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": 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