{
    "uniprot_canonical_ac": "Q00342-1",
    "uniprot_ac": "Q00342",
    "uniprot_id": "FLT3_MOUSE",
    "mass": {
        "chemical_mass": 113496.0,
        "monoisotopic_mass": 113496.0
    },
    "refseq": {
        "ac": "NP_034359",
        "name": "receptor-type tyrosine-protein kinase FLT3 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034359"
    },
    "gene_names": [
        {
            "name": "Flt3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q00342",
            "id": "Q00342"
        },
        {
            "name": "B230315G04; CD135; Flk-2; Flk2; Flt-3; Ly72; wmfl",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034359",
            "id": "NP_034359"
        },
        {
            "name": "Flk-2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q00342",
            "id": "Q00342"
        },
        {
            "name": "Flt-3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q00342",
            "id": "Q00342"
        },
        {
            "name": "Flt3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034359",
            "id": "NP_034359"
        }
    ],
    "protein_names": [
        {
            "name": "Receptor-type tyrosine-protein kinase FLT3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q00342"
        },
        {
            "name": "2.7.10.1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q00342"
        },
        {
            "name": "FL cytokine receptor; fetal liver kinase 2; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2; receptor-type tyrosine-protein kinase FLT3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034359",
            "id": "NP_034359"
        },
        {
            "name": "FL cytokine receptor",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q00342"
        },
        {
            "name": "FLK-2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q00342"
        },
        {
            "name": "FLT-3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q00342"
        },
        {
            "name": "Fetal liver kinase 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q00342"
        },
        {
            "name": "Fms-like tyrosine kinase 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q00342"
        },
        {
            "name": "Tyrosine-protein kinase receptor flk-2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q00342"
        },
        {
            "name": "receptor-type tyrosine-protein kinase FLT3 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034359",
            "id": "NP_034359"
        }
    ],
    "function": [
        {
            "annotation": "Activation of neuronal FLT3 promotes exaggerated sensorial and emotional pain-related behaviors facilitating the transition from acute to chronic pain.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_034359",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034359"
                },
                {
                    "database": "PubMed",
                    "id": "36646299",
                    "url": "https://glygen.org/publication/PubMed/36646299"
                }
            ]
        },
        {
            "annotation": "Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q00342",
                    "url": "https://www.uniprot.org/uniprot/Q00342#function"
                },
                {
                    "database": "PubMed",
                    "id": "20457904",
                    "url": "https://glygen.org/publication/PubMed/20457904"
                },
                {
                    "database": "PubMed",
                    "id": "8920882",
                    "url": "https://glygen.org/publication/PubMed/8920882"
                },
                {
                    "database": "PubMed",
                    "id": "21516120",
                    "url": "https://glygen.org/publication/PubMed/21516120"
                },
                {
                    "database": "PubMed",
                    "id": "19286519",
                    "url": "https://glygen.org/publication/PubMed/19286519"
                },
                {
                    "database": "PubMed",
                    "id": "18469816",
                    "url": "https://glygen.org/publication/PubMed/18469816"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050458",
            "recommended_name": {
                "id": "DOID:0050458",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050458",
                "name": "juvenile myelomonocytic leukemia",
                "description": "A myelodysplastic/myeloproliferative neoplasm that is characterized by the uncontrolled growth of monocytes."
            },
            "synonyms": [
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "juvenile myelomonocytic leukemia",
                    "description": "A myelodysplastic/myeloproliferative neoplasm of childhood that is characterized by proliferation principally of the granulocytic and monocytic lineages. Myelomonocytic proliferation is seen in the bone marrow and the blood. The leukemic cells may infiltrate any tissue, however liver, spleen, lymph nodes, skin, and respiratory tract are the most common sites of involvement. (WHO, 2001)"
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "chronic myelomonocytic leukaemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "chronic myelomonocytic leukemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "JCML",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "JMML",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "juvenile chronic myelogenous leukaemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "juvenile chronic myelogenous leukemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "juvenile chronic myeloid leukaemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "juvenile chronic myeloid leukemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "juvenile chronic myelomonocytic leukaemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "juvenile chronic myelomonocytic leukemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "juvenile myelomonocytic leukemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "juvenile myelomonocytic leukemia, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "leukemia, juvenile myelomonocytic, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "leukemia, juvenile myelomonocytic, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "leukemia, chronic myelomonocytic",
                    "description": ""
                },
                {
                    "id": "MONDO:0011908",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011908",
                    "name": "leukemia, juvenile myelomonocytic",
                    "description": ""
                },
                {
                    "id": "MIM:607785",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/607785",
                    "name": "Leukemia, juvenile myelomonocytic",
                    "description": "Leukemia, juvenile myelomonocytic"
                }
            ],
            "evidence": [
                {
                    "id": "0050458",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050458"
                }
            ]
        },
        {
            "disease_id": "DOID:0050861",
            "recommended_name": {
                "id": "DOID:0050861",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050861",
                "name": "colorectal adenocarcinoma",
                "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0050861",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050861"
                }
            ]
        },
        {
            "disease_id": "DOID:0050866",
            "recommended_name": {
                "id": "DOID:0050866",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050866",
                "name": "oral squamous cell carcinoma",
                "description": "An oral cavity cancer that has_material_basis_in squamous cells."
            },
            "synonyms": [
                {
                    "id": "DOID:0050866",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050866",
                    "name": "mouth squamous cell carcinoma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0050866",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050866"
                }
            ]
        },
        {
            "disease_id": "DOID:0080630",
            "recommended_name": {
                "id": "DOID:0080630",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080630",
                "name": "B-lymphoblastic leukemia/lymphoma",
                "description": "A B-cell acute lymphoblastic leukemia that is characterized by the presence of too many B-cell lymphoblasts in the blood and bone marrow."
            },
            "synonyms": [
                {
                    "id": "DOID:0080630",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080630",
                    "name": "precursor B lymphoblastic lymphoma/leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:0080630",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080630",
                    "name": "B-ALL",
                    "description": ""
                },
                {
                    "id": "DOID:0080630",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080630",
                    "name": "B lymphoblastic leukemia/lymphoma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0080630",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080630"
                }
            ]
        },
        {
            "disease_id": "DOID:0081082",
            "recommended_name": {
                "id": "DOID:0081082",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0081082",
                "name": "acute myelomonocytic leukemia",
                "description": "An acute myeloid leukemia that is characterized by the proliferation of both neutrophil and monocyte precursors."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0081082",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081082"
                }
            ]
        },
        {
            "disease_id": "DOID:10283",
            "recommended_name": {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10283",
                "name": "prostate cancer",
                "description": "A male reproductive organ cancer that is located_in the prostate."
            },
            "synonyms": [
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "NGP - new growth of prostate",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "hereditary prostate cancer",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "malignant tumor of the prostate",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostate cancer, familial",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostate neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostatic cancer",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostatic neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "tumor of the prostate",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, type 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "HPC9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, 12",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene."
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "EHBP1 familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "familial prostate cancer caused by mutation in EHBP1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, type 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "HPC12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, type 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "HPC5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, susceptibility to, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "HPC3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, susceptibility to, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "HPC4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, on chromosome 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, 13",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene."
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "MSMB familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "familial prostate cancer caused by mutation in MSMB",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, type 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "HPC13",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, type 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "HPC8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "predisposing for prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, type 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "HPC6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "prostate cancer, hereditary, 10",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "HPC10",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "prostate cancer, hereditary, 10",
                    "description": ""
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                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "familial prostate carcinoma",
                    "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma."
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "hereditary prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "hereditary prostate carcinoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
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                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
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                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, familial",
                    "description": ""
                },
                {
                    "id": "MONDO:0023122",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0023122",
                    "name": "prostate cancer, hereditary",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer, hereditary, 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "HPC7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer, hereditary, 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer aggressiveness",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, 1",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene."
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "RNASEL familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "familial prostate cancer caused by mutation in RNASEL",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
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                    "name": "prostate cancer, hereditary, type 1",
                    "description": ""
                },
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                    "resource": "MONDO",
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                    "description": ""
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                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
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                    "description": ""
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                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "prostate cancer, hereditary, 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "HPC11",
                    "description": ""
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                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "prostate cancer, hereditary, 11",
                    "description": ""
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                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "prostate cancer, hereditary, 14",
                    "description": ""
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                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "HPC14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "prostate cancer, hereditary, 14",
                    "description": ""
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                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "prostate cancer, hereditary, 15",
                    "description": ""
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                    "id": "MONDO:0012770",
                    "resource": "MONDO",
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                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "prostate cancer, hereditary, 15",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "prostate cancer, hereditary, X-linked 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "HPCX1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "prostate cancer, hereditary, X-linked 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
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                    "name": "prostate cancer susceptibility, X-linked",
                    "description": ""
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                {
                    "id": "MONDO:0010405",
                    "resource": "MONDO",
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                    "description": ""
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                {
                    "id": "MONDO:0010405",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010405",
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                    "description": ""
                },
                {
                    "id": "MONDO:0010405",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                    "name": "prostate cancer, hereditary, X-linked 2",
                    "description": ""
                },
                {
                    "id": "MIM:611868",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611868",
                    "name": "Prostate cancer, hereditary, 12",
                    "description": "Prostate cancer, hereditary, 12"
                },
                {
                    "id": "MIM:611928",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611928",
                    "name": "Prostate cancer, hereditary, 13",
                    "description": "Prostate cancer, hereditary, 13"
                },
                {
                    "id": "MIM:176807",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/176807",
                    "name": "Prostate cancer",
                    "description": "Prostate cancer"
                },
                {
                    "id": "MIM:601518",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/601518",
                    "name": "Prostate cancer, hereditary, 1",
                    "description": "Prostate cancer, hereditary, 1"
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                    "id": "MIM:611955",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611955",
                    "name": "Prostate cancer, hereditary, 11",
                    "description": "Prostate cancer, hereditary, 11"
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            ],
            "evidence": [
                {
                    "id": "10283",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10283"
                }
            ]
        },
        {
            "disease_id": "DOID:162",
            "recommended_name": {
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                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:162",
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            },
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "malignant neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "malignant tumor",
                    "description": ""
                },
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "primary cancer",
                    "description": ""
                }
            ],
            "evidence": [
                {
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                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:162"
                }
            ]
        },
        {
            "disease_id": "DOID:305",
            "recommended_name": {
                "id": "DOID:305",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:305",
                "name": "carcinoma",
                "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells."
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            "synonyms": [
                {
                    "id": "DOID:305",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:305",
                    "name": "epithelial cancer",
                    "description": ""
                },
                {
                    "id": "DOID:305",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:305",
                    "name": "epithelioma",
                    "description": ""
                },
                {
                    "id": "DOID:305",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:305",
                    "name": "malignant Epithelioma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "305",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:305"
                }
            ]
        },
        {
            "disease_id": "DOID:4971",
            "recommended_name": {
                "id": "DOID:4971",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:4971",
                "name": "myelofibrosis",
                "description": "A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue."
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                    "id": "DOID:4971",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4971",
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                },
                {
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                    "resource": "Disease Ontology",
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                    "name": "Aleukemic myelosis",
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                },
                {
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4971",
                    "name": "Megakaryocytic myelosclerosis",
                    "description": ""
                },
                {
                    "id": "DOID:4971",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4971",
                    "name": "bone Marrow Fibrosis",
                    "description": ""
                },
                {
                    "id": "DOID:4971",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4971",
                    "name": "myelosclerosis",
                    "description": ""
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4971",
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                    "resource": "MONDO",
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                },
                {
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                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
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                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "Agnogenic myeloid metaplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "CIMF",
                    "description": ""
                },
                {
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                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "aleukemic myelosis",
                    "description": ""
                },
                {
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                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "bone marrow fibrosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "chronic idiopathic myelofibrosis",
                    "description": ""
                },
                {
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                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "idiopathic bone marrow fibrosis",
                    "description": ""
                },
                {
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                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "idiopathic myelofibrosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "megakaryocytic myelosclerosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "myelofibrosis with myeloid metaplasia, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "myelofibrosis, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "myelosclerosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "myelosclerosis with myeloid metaplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "osteomyelofibrosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "primary myelofibrosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "myelofibrosis with myeloid metaplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "myelofibrosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009692",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009692",
                    "name": "myeloid metaplasia",
                    "description": ""
                },
                {
                    "id": "MIM:254450",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/254450",
                    "name": "Myelofibrosis with myeloid metaplasia",
                    "description": "Myelofibrosis with myeloid metaplasia"
                }
            ],
            "evidence": [
                {
                    "id": "4971",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:4971"
                }
            ]
        },
        {
            "disease_id": "DOID:684",
            "recommended_name": {
                "id": "DOID:684",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:684",
                "name": "hepatocellular carcinoma",
                "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver."
            },
            "synonyms": [
                {
                    "id": "DOID:684",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:684",
                    "name": "Hepatoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007256",
                    "resource": "MONDO",
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                    "url": "https://www.alliancegenome.org/disease/DOID:9119"
                }
            ]
        },
        {
            "disease_id": "DOID:9952",
            "recommended_name": {
                "id": "DOID:9952",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:9952",
                "name": "acute lymphoblastic leukemia",
                "description": "A acute leukemia that is characterized by over production of lymphoblasts."
            },
            "synonyms": [
                {
                    "id": "DOID:9952",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9952",
                    "name": "ALL",
                    "description": ""
                },
                {
                    "id": "DOID:9952",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9952",
                    "name": "precursor lymphoblastic lymphoma/leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:9952",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9952",
                    "name": "acute lymphoblastic leukaemia",
                    "description": ""
                },
                {
                    "id": "DOID:9952",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9952",
                    "name": "acute lymphocytic leukaemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "lymphoblastic leukemia, acute, with lymphomatous features",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "leukemia, acute lymphoblastic",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "lymphoblastic leukemia, acute, with lymphomatous features",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "lall",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "lymphomatous All",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphocytic, susceptibility to, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "T-cell acute lymphoblastic leukemia, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, T-cell acute lymphoblastic, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, T-cell acute lymphocytic, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphoblastic, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphocytic, Philadelphia chromosome positive, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphocytic, susceptibility to, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "ALL",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "All1",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, B-cell acute lymphoblastic, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, T-cell acute lymphoblastic, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphoblastic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphoblastic, B-Hyperdiploid, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphoblastic, susceptibility to, 1",
                    "description": ""
                },
                {
                    "id": "MIM:613065",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/613065",
                    "name": "Leukemia, acute lymphoblastic",
                    "description": "Leukemia, acute lymphoblastic"
                }
            ],
            "evidence": [
                {
                    "id": "9952",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:9952"
                }
            ]
        }
    ],
    "snv": [
        {
            "evidence": [
                {
                    "id": "rs3388815230",
                    "database": "dbSNP",
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388815230"
                }
            ],
            "glycoeffect": [
                "n-glyco-sequon-gain",
                "o-glyco-site-loss"
            ],
            "start_pos": 546,
            "end_pos": 546,
            "sequence_org": "Y",
            "sequence_mut": "N",
            "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (YAT->NAT).",
            "chr_id": "5",
            "chr_pos": "147291887",
            "ref_nt": "T",
            "alt_nt": "null",
            "minor_allelic_frequency": "",
            "site_lbl": "Y546",
            "keywords": [
                "ebi",
                "germline"
            ]
        }
    ],
    "mutagenesis": [
        {
            "start_pos": 645,
            "end_pos": 645,
            "sequence_org": "K",
            "sequence_mut": "A",
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                {
                    "database": "UniProtKB",
                    "id": "Q00342",
                    "url": "https://www.uniprot.org/uniprot/Q00342"
                },
                {
                    "database": "PubMed",
                    "id": "10409713",
                    "url": "https://glygen.org/publication/PubMed/10409713"
                }
            ]
        }
    ],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
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                {
                    "database": "UniProtKB",
                    "id": "Q00342",
                    "url": "https://www.uniprot.org/uniprot/Q00342"
                }
            ],
            "common_name": "Mouse"
        }
    ],
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        {
            "name": "Flt3",
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            "locus": {
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                "start_pos": 147267551,
                "end_pos": 147337299,
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                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000042817",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000042817"
                    }
                ]
            }
        }
    ],
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        {
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            "database": "Bgee",
            "categories": [
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            ]
        },
        {
            "id": "2.7.10.1",
            "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.10.1&UniProtAcc=Q00342",
            "database": "BRENDA",
            "categories": [
                "Enzyme and Pathway"
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        },
        {
            "id": "CHEMBL2034796",
            "url": "https://www.ebi.ac.uk/chembldb/target/inspect/CHEMBL2034796",
            "database": "ChEMBL",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "14255",
            "url": "https://www.ncbi.nlm.nih.gov/gene/14255",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000719",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001245",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001824",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001824",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003599",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR007110",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR008266",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011009",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013151",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017441",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR020635",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036179",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:14255",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:14255",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "95559",
            "url": "http://www.informatics.jax.org/marker/MGI:95559",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "NSQGESC",
            "url": "https://omabrowser.org/oma/group/NSQGESC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1614410at2759",
            "url": "http://www.orthodb.org/?query=1614410at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24416",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24416:SF356",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416:SF356",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00047",
            "url": "http://pfam.xfam.org/family/PF00047",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07714",
            "url": "http://pfam.xfam.org/family/PF07714",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q00342",
            "url": "http://purl.obolibrary.org/obo/PR_Q00342",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-109704",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-109704",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-1257604",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1257604",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-5673001",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5673001",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-6811558",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6811558",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-9607240",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9607240",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-9706369",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706369",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-9706374",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706374",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_034359",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034359",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "10596",
            "url": "https://www.rhea-db.org/rhea/10596",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "Q00342",
            "url": "https://www.uniprot.org/uniprot/Q00342",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q00342-1",
            "url": "https://www.uniprot.org/uniprot/Q00342-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q3UEW6",
            "url": "https://www.uniprot.org/uniprot/Q3UEW6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q3UEW6-1",
            "url": "https://www.uniprot.org/uniprot/Q3UEW6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MRALAQRSDRRLLLLVVLSVMILETVTNQDLPVIKCVLISHENNGSSAGKPSSYRMVRGSPEDLQCTPRRQSEGTVYEAATVEVAESGSITLQVQLATPGDLSCLWVFKHSSLGCQPHFDLQNRGIVSMAILNVTETQAGEYLLHIQSEAANYTVLFTVNVRDTQLYVLRRPYFRKMENQDALLCISEGVPEPTVEWVLCSSHRESCKEEGPAVVRKEEKVLHELFGTDIRCCARNALGRESTKLFTIDLNQAPQSTLPQLFLKVGEPLWIRCKAIHVNHGFGLTWELEDKALEEGSYFEMSTYSTNRTMIRILLAFVSSVGRNDTGYYTCSSSKHPSQSALVTILEKGFINATSSQEEYEIDPYEKFCFSVRFKAYPRIRCTWIFSQASFPCEQRGLEDGYSISKFCDHKNKPGEYIFYAENDDAQFTKMFTLNIRKKPQVLANASASQASCSSDGYPLPSWTWKKCSDKSPNCTEEIPEGVWNKKANRKVFGQWVSSSTLNMSEAGKGLLVKCCAYNSMGTSCETIFLNSPGPFPFIQDNISFYATIGLCLPFIVVLIVLICHKYKKQFRYESQLQMIQVTGPLDNEYFYVDFRDYEYDLKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAVKMLKEKADSCEKEALMSELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQAHSNSSMPGSREVQLHPPLDQLSGFNGNSIHSEDEIEYENQKRLAEEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAEAEEAMYQNMGGNVPEHPSIYQNRRPLSREAGSEPPSPQAQVKIHRERS",
        "length": 1000,
        "header": "sp|Q00342-1|FLT3_MOUSE Isoform 1 of Receptor-type tyrosine-protein kinase FLT3  OS=Mus musculus OX=10090 GN=Flt3 PE=1 SV=2 CANONICAL=Q00342-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q00342-1",
            "url": "",
            "sequence": {
                "sequence": "MRALAQRSDRRLLLLVVLSVMILETVTNQDLPVIKCVLISHENNGSSAGKPSSYRMVRGSPEDLQCTPRRQSEGTVYEAATVEVAESGSITLQVQLATPGDLSCLWVFKHSSLGCQPHFDLQNRGIVSMAILNVTETQAGEYLLHIQSEAANYTVLFTVNVRDTQLYVLRRPYFRKMENQDALLCISEGVPEPTVEWVLCSSHRESCKEEGPAVVRKEEKVLHELFGTDIRCCARNALGRESTKLFTIDLNQAPQSTLPQLFLKVGEPLWIRCKAIHVNHGFGLTWELEDKALEEGSYFEMSTYSTNRTMIRILLAFVSSVGRNDTGYYTCSSSKHPSQSALVTILEKGFINATSSQEEYEIDPYEKFCFSVRFKAYPRIRCTWIFSQASFPCEQRGLEDGYSISKFCDHKNKPGEYIFYAENDDAQFTKMFTLNIRKKPQVLANASASQASCSSDGYPLPSWTWKKCSDKSPNCTEEIPEGVWNKKANRKVFGQWVSSSTLNMSEAGKGLLVKCCAYNSMGTSCETIFLNSPGPFPFIQDNISFYATIGLCLPFIVVLIVLICHKYKKQFRYESQLQMIQVTGPLDNEYFYVDFRDYEYDLKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAVKMLKEKADSCEKEALMSELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQAHSNSSMPGSREVQLHPPLDQLSGFNGNSIHSEDEIEYENQKRLAEEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAEAEEAMYQNMGGNVPEHPSIYQNRRPLSREAGSEPPSPQAQVKIHRERS",
                "length": 1000,
                "header": "sp|Q00342-1|FLT3_MOUSE Isoform 1 of Receptor-type tyrosine-protein kinase FLT3  OS=Mus musculus OX=10090 GN=Flt3 PE=1 SV=2 CANONICAL=Q00342-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "Q3UEW6-1",
            "url": "",
            "sequence": {
                "sequence": "MRALAQRSDRRLLLLVVLSVMILETVTNQDLPVIKCVLISHENNGSSAGKPSSYRMVRGSPEDLQCAPRRQSEGTVYEAATVEVAESGSITLQVQLATPGDLSCLWVFKHSSLGCQPHFDLQNRGIVSMAILNVTETQAGEYLLHIQSEAANYTVLFTVNVRDTQLYVLRRPYFRKMENQDALLCISEGVPEPTVEWVLCSSHRESCKEEGPAVVRKEEKVLHELFGTDIRCCARNALGRECTKLFTIDLNQAPQSTLPQLFLKVGEPLWIRCKAIHVNHGFGLTWELEDKALEEGSYFEMSTYSTNRTMIRILLAFVSSVGRNDTGYYTCSSSKHPSQSALVTILEKGFINATSSQEEYEIDPYEKFCFSVRFKAYPRIRCTWIFSQASFPCEQRGLEDGYSISKFCDHKNKPGEYIFYAENDDAQFTKMFTLNIRKKPQVLANASASQASCSSDGYPLPSWTWKKCSDKSPNCTEEIPEGVWNKKANRKVFGQWVSSSTLNMSEAGKGLLVKCCAYNSMGTSCETIFLNSPGPFPFIQDNISFYATIGLCLPFIVVLIVLICHKYKKQFRYESQLQMIQVTGPLDNEYFYVDFRDYEYDLKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAVKMLKEKADSCEKEALMSELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQAHSNSSMPGSREVQLHPPLDQLSGFNGNLIHSEDEIEYENQKRLAEEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAEAEEAMYQNMGGNVPEHPSIYQNRRPLSREAGSEPPSPQAQVKIHGERS",
                "length": 1000,
                "header": "tr|Q3UEW6-1|FLT3_MOUSE Computationally mapped isoform of Receptor-type tyrosine-protein kinase FLT3  OS=Mus musculus OX=10090 GN=Flt3 PE=1 SV=1 CANONICAL=Q00342-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 147337075,
                "end_pos": 147267984,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
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            "journal": "Oncogene",
            "date": "1993",
            "authors": "Dubreuil P., Marchetto S., Birnbaum D., Rosnet O., Mannoni P., Rottapel R., Lavezzi C., Maroc N.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q00342",
                    "url": "https://www.uniprot.org/uniprot/Q00342"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "8384358",
                    "url": "https://glygen.org/publication/PubMed/8384358"
                }
            ]
        },
        {
            "title": "Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.",
            "journal": "J. Exp. Med.",
            "date": "1996",
            "authors": "Maraskovsky E., Shortman K., Lyman S.D., Teepe M., Brasel K., McKenna H.J., Roux E.R.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q00342",
                    "url": "https://www.uniprot.org/uniprot/Q00342"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "8920882",
                    "url": "https://glygen.org/publication/PubMed/8920882"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:14255",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:14255",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-109704",
            "name": "PI3K Cascade",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-109704",
            "resource": "Reactome",
            "description": "PI3K Cascade"
        },
        {
            "id": "R-MMU-1257604",
            "name": "PIP3 activates AKT signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1257604",
            "resource": "Reactome",
            "description": "PIP3 activates AKT signaling"
        },
        {
            "id": "R-MMU-5673001",
            "name": "RAF/MAP kinase cascade",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5673001",
            "resource": "Reactome",
            "description": "RAF/MAP kinase cascade"
        },
        {
            "id": "R-MMU-6811558",
            "name": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6811558",
            "resource": "Reactome",
            "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
        },
        {
            "id": "R-MMU-9607240",
            "name": "FLT3 Signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9607240",
            "resource": "Reactome",
            "description": "FLT3 Signaling"
        },
        {
            "id": "R-MMU-9706369",
            "name": "Negative regulation of FLT3",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706369",
            "resource": "Reactome",
            "description": "Negative regulation of FLT3"
        },
        {
            "id": "R-MMU-9706374",
            "name": "FLT3 signaling through SRC family kinases",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706374",
            "resource": "Reactome",
            "description": "FLT3 signaling through SRC family kinases"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P36888-1",
            "protein_name": "Receptor-type tyrosine-protein kinase FLT3",
            "gene_name": "FLT3",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MPALARDGGQLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDGRVSECPHTYQNRRPFSREMDLGLLSPQAQVEDS",
                "length": 993
            },
            "evidence": [
                {
                    "id": "45229369",
                    "url": "http://www.informatics.jax.org/homology/45229369",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 38,
                "go_terms": [
                    {
                        "name": "system development",
                        "id": "GO:0048731",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein phosphorylation",
                        "id": "GO:0006468",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "transmembrane receptor protein tyrosine kinase signaling pathway",
                        "id": "GO:0007169",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "hemopoiesis",
                        "id": "GO:0030097",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "animal organ regeneration",
                        "id": "GO:0031100",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031100",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to glucocorticoid stimulus",
                        "id": "GO:0071385",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071385",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to organonitrogen compound",
                        "id": "GO:0010243",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010243",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "myeloid progenitor cell differentiation",
                        "id": "GO:0002318",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002318",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of interferon-alpha production",
                        "id": "GO:0032727",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032727",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "pro-B cell differentiation",
                        "id": "GO:0002328",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002328",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dendritic cell homeostasis",
                        "id": "GO:0036145",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036145",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of protein phosphorylation",
                        "id": "GO:0001934",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001934",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell population proliferation",
                        "id": "GO:0008283",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of cell population proliferation",
                        "id": "GO:0008285",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of interleukin-6 production",
                        "id": "GO:0032715",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of tumor necrosis factor production",
                        "id": "GO:0032720",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032720",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "homeostasis of number of cells within a tissue",
                        "id": "GO:0048873",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048873",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of kinase activity",
                        "id": "GO:0033674",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033674",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein autophosphorylation",
                        "id": "GO:0046777",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "post-embryonic development",
                        "id": "GO:0009791",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009791",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "spleen development",
                        "id": "GO:0048536",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048536",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "B cell differentiation",
                        "id": "GO:0030183",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of type II interferon production",
                        "id": "GO:0032729",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to cytokine stimulus",
                        "id": "GO:0071345",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071345",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to virus",
                        "id": "GO:0098586",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lymphoid progenitor cell differentiation",
                        "id": "GO:0002320",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002320",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytokine-mediated signaling pathway",
                        "id": "GO:0019221",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of multicellular organism growth",
                        "id": "GO:0040018",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040018",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "common myeloid progenitor cell proliferation",
                        "id": "GO:0035726",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035726",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "leukocyte homeostasis",
                        "id": "GO:0001776",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001776",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lymphocyte proliferation",
                        "id": "GO:0046651",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046651",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "pro-T cell differentiation",
                        "id": "GO:0002572",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002572",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dendritic cell differentiation",
                        "id": "GO:0097028",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097028",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "antigen processing and presentation",
                        "id": "GO:0019882",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019882",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of interleukin-12 production",
                        "id": "GO:0032735",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032735",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lymph node development",
                        "id": "GO:0048535",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048535",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lymphocyte differentiation",
                        "id": "GO:0030098",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030098",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of B cell differentiation",
                        "id": "GO:0045578",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045578",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 10,
                "go_terms": [
                    {
                        "name": "ATP binding",
                        "id": "GO:0005524",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nuclear glucocorticoid receptor binding",
                        "id": "GO:0035259",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035259",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein self-association",
                        "id": "GO:0043621",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043621",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein-containing complex binding",
                        "id": "GO:0044877",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "transmembrane receptor protein tyrosine kinase activity",
                        "id": "GO:0004714",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein tyrosine kinase activity",
                        "id": "GO:0004713",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "growth factor binding",
                        "id": "GO:0019838",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ubiquitin protein ligase binding",
                        "id": "GO:0031625",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "phosphatidylinositol 3-kinase binding",
                        "id": "GO:0043548",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytokine receptor activity",
                        "id": "GO:0004896",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 8,
                "go_terms": [
                    {
                        "name": "endoplasmic reticulum",
                        "id": "GO:0005783",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein-containing complex",
                        "id": "GO:0032991",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endoplasmic reticulum lumen",
                        "id": "GO:0005788",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell surface",
                        "id": "GO:0009986",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "receptor complex",
                        "id": "GO:0043235",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "external side of plasma membrane",
                        "id": "GO:0009897",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q00342",
                                "url": "https://www.uniprot.org/uniprot/Q00342"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 133,
            "end_pos": 135,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 152,
            "end_pos": 154,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 307,
            "end_pos": 309,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 324,
            "end_pos": 326,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 352,
            "end_pos": 354,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 445,
            "end_pos": 447,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 44,
            "end_pos": 46,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 474,
            "end_pos": 476,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 503,
            "end_pos": 505,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 542,
            "end_pos": 544,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 627,
            "end_pos": 629,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 723,
            "end_pos": 725,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 735,
            "end_pos": 737,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 941,
            "end_pos": 943,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [
        {
            "id": "10596",
            "name": "",
            "equation": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q63132-1",
                "Q9WUD9-1",
                "P57760-1",
                "P35739-1",
                "F1LYY7-1",
                "A0A8I6GCV6-1",
                "Q63117-1",
                "Q5U2X5-1",
                "Q63474-1",
                "O08680-1",
                "O35346-1",
                "P54757-1",
                "P54758-1",
                "P54759-1",
                "P70600-1",
                "Q00495-1",
                "Q03351-1",
                "Q04589-1",
                "P06494-1",
                "P09759-1",
                "P29321-1",
                "P32577-1",
                "Q6XUX2-1",
                "Q4V8A3-1",
                "Q62662-1",
                "Q62799-1",
                "Q62844-1",
                "Q62956-1",
                "Q63184-1",
                "Q63470-1",
                "Q498D6-1",
                "Q01621-1",
                "Q6P6U0-1",
                "Q63604-1",
                "P09760-1",
                "Q01986-1",
                "Q62862-1",
                "Q63572-1",
                "Q07014-1",
                "Q4KSH7-1",
                "G3V9H8-1",
                "P15127-1",
                "O08775-1",
                "P53767-1",
                "Q05030-1",
                "P55146-1",
                "Q64725-1",
                "Q63802-1",
                "Q64716-1",
                "P09215-1",
                "Q62689-1",
                "F1LM93-1",
                "P36506-1",
                "P20786-1",
                "P24062-1",
                "Q924U5-1",
                "Q63272-1",
                "B2RYC7-1",
                "P41243-1",
                "M0RDA4-1",
                "Q62838-1",
                "Q63116-1",
                "A0A8I6AM23-1",
                "P50545-1",
                "P57097-1",
                "P97523-1",
                "Q91ZT1-1",
                "D4A7W7-1",
                "F1LVI0-1",
                "E9PSY0-1",
                "A0A0G2K6M9-1",
                "F1LSN4-1",
                "F1MAJ0-1",
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                "A0A8I6A5T6-1",
                "D3ZDS3-1",
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                "F1LSG7-1",
                "F1LRZ0-1",
                "D3ZBN3-1",
                "F1M0N1-1",
                "G3V6K6-1",
                "D3ZD03-1",
                "D3ZZK3-1",
                "E9PT20-1",
                "D4A584-1",
                "D3ZDH4-1",
                "A0A8I5ZVE3-1",
                "A0A8I6AWX7-1",
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                "B5DFD6-1",
                "Q5FVG7-1",
                "D3ZCD0-1",
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                "G3V783-1",
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                "P42679-1",
                "P08922-1",
                "P07947-1",
                "Q12866-1",
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                "Q07912-1",
                "P42684-1",
                "Q9UF33-1",
                "P10721-1",
                "P08069-1",
                "P06239-1",
                "P51451-1",
                "Q06187-1",
                "P51813-1",
                "Q9UIG0-1",
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                "P49761-4",
                "Q9HAZ1-1",
                "P49759-1",
                "P07333-1",
                "Q5JZY3-1",
                "Q6XUX3-1",
                "P00533-1",
                "Q9Y463-1",
                "P29317-1",
                "Q9NR20-1",
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                "P54760-1",
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                "Q16832-1",
                "Q15375-1",
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                "P22455-1",
                "P16591-1",
                "P29322-1",
                "P54756-1",
                "P29320-1",
                "Q08345-1",
                "Q92630-1",
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                "P36888-1",
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                "P21860-1",
                "Q14289-1",
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                "P21802-1",
                "P52333-1",
                "P11362-1",
                "P42685-1",
                "P06213-1",
                "P14616-1",
                "Q05655-1",
                "Q08881-1",
                "P07332-1",
                "P08631-1",
                "P29376-1",
                "O60674-1",
                "P23458-1",
                "P09769-1",
                "P43405-1",
                "P06241-1",
                "P07948-1",
                "P46734-1",
                "P45985-1",
                "Q02750-1",
                "P52564-1",
                "O14733-1",
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                "Q16620-1",
                "P08581-1",
                "P04629-1",
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                "Q01974-1",
                "P09619-1",
                "P07949-1",
                "Q504Y2-1",
                "P34925-1",
                "P16234-1",
                "Q13882-1",
                "Q04912-1",
                "O43353-1",
                "Q06418-1",
                "P30530-1",
                "Q96KB5-1",
                "Q15569-1",
                "Q96S53-1",
                "Q6J9G0-1",
                "P42680-1",
                "P35916-2",
                "P0C1S8-1",
                "P17948-1",
                "P29597-1",
                "P42681-1",
                "P35590-1",
                "Q13470-1",
                "P33981-1",
                "P30291-1",
                "P12931-1",
                "P35968-1",
                "P43403-1",
                "O75716-1",
                "Q02763-1",
                "Q9H3Y6-1",
                "P35790-1",
                "P14618-1",
                "P24604-1",
                "O54967-1",
                "P00520-1",
                "Q9Z188-1",
                "P35969-1",
                "P52332-1",
                "P08923-1",
                "Q00342-1",
                "Q62120-1",
                "Q4JIM5-1",
                "P97504-1",
                "P42682-1",
                "Q60629-1",
                "P97793-1",
                "P16277-1",
                "O35491-1",
                "O35492-1",
                "O35493-1",
                "Q9Z277-1",
                "P35991-1",
                "P22518-1",
                "Q8BYG9-1",
                "P54754-1",
                "P54761-1",
                "Q6XUX1-1",
                "Q62371-1",
                "Q60750-1",
                "Q61527-1",
                "Q62413-1",
                "Q61214-1",
                "Q61772-1",
                "Q61851-1",
                "Q922Y0-1",
                "Q922K9-1",
                "O09127-1",
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                "Q03142-1",
                "P29319-1",
                "Q01279-1",
                "P70424-1",
                "P21803-1",
                "Q8CBF3-1",
                "P41241-1",
                "Q03963-1",
                "Q8BI55-1",
                "P54763-3",
                "P16879-1",
                "P09581-1",
                "P34152-3",
                "P14234-1",
                "P39688-1",
                "Q03146-1",
                "Q03145-1",
                "Q61526-1",
                "P70451-1",
                "Q5U4C9-1",
                "Q9QVP9-1",
                "Q03137-1",
                "Q60751-1",
                "Q62137-1",
                "P28867-1",
                "P25911-1",
                "P48025-1",
                "Q9WTL4-1",
                "P41242-1",
                "P05532-1",
                "P06240-1",
                "P08103-1",
                "P15208-1",
                "Q03526-1",
                "Q9WVS7-1",
                "P70236-1",
                "P31938-1",
                "P47809-1",
                "Q61846-1",
                "Q60805-1",
                "Q63932-1",
                "O09110-1",
                "P26618-1",
                "Q8CE90-1",
                "P16056-1",
                "P05622-1",
                "P15209-1",
                "Q6VNS1-1",
                "Q61006-1",
                "Q3UFB7-1",
                "Q5RJI4-1",
                "Q9JJ78-1",
                "P58801-1",
                "P55144-1",
                "Q8VCT9-1",
                "O70146-1",
                "Q62190-1",
                "Q62270-1",
                "P35546-1",
                "P35761-1",
                "Q9Z138-1",
                "Q9R117-1",
                "O88697-1",
                "P05480-2",
                "Q01887-1",
                "Q02858-1",
                "Q06806-1",
                "Q00993-1",
                "Q64434-1",
                "Q78DX7-1",
                "Q6J9G1-1",
                "Q99ML2-1",
                "P43404-1",
                "P35917-1",
                "P47810-1",
                "P35918-1",
                "Q04736-1",
                "Q66JT0-1",
                "O54804-1",
                "P52480-1",
                "P14680-1",
                "P21965-1",
                "P22216-1",
                "P32490-1",
                "P06784-1",
                "P08018-1",
                "P32350-1",
                "P32491-1",
                "P54199-1",
                "Q54G28-1",
                "Q54N73-1",
                "Q54R58-1",
                "P18160-1",
                "P18161-1",
                "Q54BC9-1",
                "Q54I36-1",
                "Q54QV3-1",
                "Q552C6-1",
                "Q55CL6-1",
                "Q75JK0-1",
                "Q76NV1-1",
                "Q23977-1",
                "P18475-1",
                "P09208-1",
                "P13368-1",
                "Q24145-1",
                "Q24488-1",
                "Q27324-1",
                "P08630-1",
                "P00522-1",
                "P00528-1",
                "P04412-1",
                "Q9V422-1",
                "Q9V6K3-1",
                "Q9V9J3-1",
                "Q9VBW3-1",
                "P49762-1",
                "P83102-1",
                "Q24324-1",
                "Q9VPC0-1",
                "P49657-1",
                "P54350-1",
                "P18106-4",
                "Q07407-1",
                "Q09147-1",
                "Q24592-1",
                "Q9I7F7-1",
                "Q9V3D5-1",
                "Q9VZI2-1",
                "Q9V4E5-1",
                "Q8INJ8-1",
                "Q7KJ08-1",
                "Q9VJ04-1"
            ],
            "evidence": [
                {
                    "id": "10596",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/10596"
                }
            ]
        },
        {
            "id": "R-MMU-109699",
            "name": "PI3K-containing complexes phosphorylate PIP2 to PIP3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, endosome membrane, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [
                "R-ALL-179838"
            ],
            "enzyme_list": [
                "O35082-1",
                "Q8VD65-1",
                "Q00342-1",
                "P35235-2",
                "P42337-1",
                "Q6PF93-1",
                "Q8BTI9-1",
                "P21803-1",
                "Q61851-1",
                "P16092-1",
                "Q03142-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-109699",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-109699"
                }
            ]
        },
        {
            "id": "R-MMU-2316434",
            "name": "PI3K phosphorylates PIP2 to PIP3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "O35082-1",
                "P26618-1",
                "P70424-1",
                "Q61526-1",
                "P14719-1",
                "P05480-2",
                "Q00342-1",
                "P06240-1",
                "P35235-2",
                "P05532-1",
                "P42337-1",
                "P05622-1",
                "Q8BTI9-1",
                "Q01279-1",
                "Q61527-1",
                "P39688-1",
                "Q62406-1",
                "P21803-1",
                "Q61851-1",
                "P16092-1",
                "Q61730-1",
                "P63001-1",
                "O35904-1",
                "P16056-1",
                "P70196-1",
                "Q03142-1",
                "Q8R4K2-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-2316434",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2316434"
                }
            ]
        },
        {
            "id": "R-MMU-5672965",
            "name": "RAS GEFs promote RAS nucleotide exchange",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P18052-1",
                "Q02858-1",
                "Q62120-1",
                "O35082-1",
                "Q62137-1",
                "P28652-1",
                "P26618-1",
                "P70424-1",
                "Q61526-1",
                "Q6PHZ2-1",
                "P32883-1",
                "Q00342-1",
                "P05532-1",
                "P05622-1",
                "Q01279-1",
                "Q61527-1",
                "Q923T9-1",
                "P39688-1",
                "P11798-1",
                "P52332-1",
                "P21803-1",
                "Q61851-1",
                "P16092-1",
                "P08556-1",
                "P35546-1",
                "P16056-1",
                "Q61411-1",
                "Q03142-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-5672965",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5672965"
                }
            ]
        },
        {
            "id": "R-MMU-6786789",
            "name": "FLT3LG dimer binds FLT3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "extracellular region, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-6786789",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6786789"
                }
            ]
        },
        {
            "id": "R-MMU-8854736",
            "name": "FLT3LG dimer:FLT3 binds FLT3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "extracellular region, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-8854736",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8854736"
                }
            ]
        },
        {
            "id": "R-MMU-9604767",
            "name": "FLT3LG dimer:FLT3 dimer autophosphorylates",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9604767",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9604767"
                }
            ]
        },
        {
            "id": "R-MMU-9604768",
            "name": "Active Flt3 dimer binds Grb2",
            "equation": "",
            "summary": "Feline McDonough Sarcoma-like tyrosine kinase (Flt3) is a member of the class III tyrosine kinase receptor family. Ligand binding induces conformational changes in the Flt3 receptor, which facilitates its dimerization and autophosphorylation. Once fully active, Flt3 receptors can associate with growth factor receptor-bound protein 2 (Grb2) and facilitate downstream regulation of effectors (Masson et al. 2009, Chonabayashi et al. 2013).",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9604768",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9604768"
                }
            ]
        },
        {
            "id": "R-MMU-9604980",
            "name": "Active Flt3 binds Ptpn11",
            "equation": "",
            "summary": "Feline McDonough Sarcoma-like tyrosine kinase (Flt3) is a member of the class III tyrosine kinase receptor family. Ligand binding induces conformational changes in the Flt3 receptor, which facilitates its dimerization and autophosphorylation. Once fully active, tyrosine-protein phosphatase non-receptor type 11 (Ptpn11) has been reported to directly bind to the Y599 site of Flt3 receptors thereby facilitating downstream regulation of effectors (Heiss et al. 2006, Nabinger et al. 2013). Interaction of Flt3 with Ptpn11 is known to trigger Stat5 activation in various pathological conditions.",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P35235-2"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9604980",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9604980"
                }
            ]
        },
        {
            "id": "R-MMU-9605258",
            "name": "Active Flt3 binds Fyn",
            "equation": "",
            "summary": "Feline McDonough Sarcoma-like tyrosine kinase (Flt3) is a member of the class III tyrosine kinase receptor family. Ligand binding induces conformational changes in Flt3 receptor, which facilitates its dimerization and autophosphorylation. Subsequently, tyrosine-protein kinase Fyn (Fyn) associates with the phosphorylated residues of fully active Flt3 (Y591, Y599 and pY955) through its SH2 domain (Dosil et al. 1993, Chougule et al. 2016).",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P39688-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9605258",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9605258"
                }
            ]
        },
        {
            "id": "R-MMU-9606621",
            "name": "Gab2 in Active Flt3:Grb2:Gab2 is phosphorylated",
            "equation": "",
            "summary": "Feline McDonough Sarcoma-like tyrosine kinase (Flt3) is a member of the class III tyrosine kinase receptor family. Ligand binding induces conformational changes in the Flt3 receptor, which facilitates its dimerization and autophosphorylation. Once fully active, Flt3 receptors can associate with growth factor receptor-bound protein 2 (Grb2), which then recruits Grb2-associated-binding protein 2 (Gab2). Consequently, Gab2 is phosphorylated (Zhang et al. 2000, Masson et al. 2009, Chonabayashi et al. 2013). The precise phosphorylation mechanism of Gab2 is unclear.",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9606621",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9606621"
                }
            ]
        },
        {
            "id": "R-MMU-9606623",
            "name": "Active Flt3:Grb2 binds Gab2",
            "equation": "",
            "summary": "Feline McDonough Sarcoma-like tyrosine kinase (Flt3) is a member of the class III tyrosine kinase receptor family. Ligand binding induces conformational changes in the Flt3 receptor, which facilitates its dimerization and autophosphorylation. Once fully active, Flt3 receptors can associate with growth factor receptor-bound protein 2 (Grb2). Subsequently, Grb2-associated-binding protein 2 (Gab2) binds Grb2 (Zhang et al. 2000, Masson et al. 2009, Chonabayashi et al. 2013).",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9606623",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9606623"
                }
            ]
        },
        {
            "id": "R-MMU-9606789",
            "name": "Active Flt3:Grb2:p-Y-Gab2 binds Ptpn11",
            "equation": "",
            "summary": "Feline McDonough Sarcoma-like tyrosine kinase (Flt3) is a member of the class III tyrosine kinase receptor family. Ligand binding induces conformational changes in the Flt3 receptor, which facilitates its dimerization and autophosphorylation. Once fully active, Flt3 receptors can associate with growth factor receptor-bound protein 2 (Grb2), which then recruits Grb2-associated-binding protein 2 (Gab2). Consequently, Gab2 is phosphorylated and recruits tyrosine-protein phosphatase non-receptor type 11 (Ptpn11). The serine residue at position 623 in Gab2 is known to be involved in Ptpn11 binding (Zhang et al. 2000, Arnaud et al. 2004). The precise association mechanism of Gab2 and Ptpn11 is unclear. Interaction of Flt3 with Ptpn11 is known to trigger Stat5 activation in various pathological conditions.",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P35235-2"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9606789",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9606789"
                }
            ]
        },
        {
            "id": "R-MMU-9607226",
            "name": "Active Flt3:Grb2:p-Y-Gab2 binds Pik3r1",
            "equation": "",
            "summary": "Feline McDonough Sarcoma-like tyrosine kinase (Flt3) is a member of the class III tyrosine kinase receptor family. Ligand binding induces conformational changes in the Flt3 receptor, which facilitates its dimerization and autophosphorylation. Once fully active, Flt3 receptors can associate with Growth factor receptor-bound protein 2 (Grb2), which then recruits Grb2-associated-binding protein 2 (Gab2). Ultimately, Gab2 is phosphorylated and recruits Phosphatidylinositol 3-kinase regulatory subunit alpha (Pik3r1). The p85 alpha subunit of Pik3 is known to bind with Gab2 (Zhang et al. 2000, Masson et al. 2009).",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9607226",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9607226"
                }
            ]
        },
        {
            "id": "R-MMU-9607301",
            "name": "Active FLT3:GRB2 binds SOS1",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9607301",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9607301"
                }
            ]
        },
        {
            "id": "R-MMU-9607304",
            "name": "SOS1-mediated nucleotide exchange of RAS downstream of FLT3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P32883-1",
                "Q00342-1",
                "P08556-1",
                "Q61411-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9607304",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9607304"
                }
            ]
        },
        {
            "id": "R-MMU-9609272",
            "name": "Active Flt3 binds Hck",
            "equation": "",
            "summary": "Feline McDonough Sarcoma-like tyrosine kinase (Flt3) is a member of the class III tyrosine kinase receptor family. Ligand binding induces conformational changes in the Flt3 receptor, which facilitates its dimerization and autophosphorylation. Tyrosine-protein kinase HCK (Hck) associates with the phosphorylated Y589 and Y591 residues of Flt3. This binding results in further phosphorylation of the Flt3 receptor to make it fully active (Heiss et al. 2006, Mitina et al. 2007). There may be more unknown binding sites for Hck on Flt3.",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P08103-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9609272",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9609272"
                }
            ]
        },
        {
            "id": "R-MMU-9645128",
            "name": "Activators bind Stat5",
            "equation": "",
            "summary": "Signal transducer and activator of transcription (Stat5a/Stat5b) is a key component in several cell signaling and gene transcription process and regulated cell survival and proliferation. Stat5 is activated by multiple upstream activators including cytokines and growth factors. The process begins when an active upstream regulator binds Stat5 to initiate its phosphorylation (Sarah C et al, 2013).",
            "cellular_location": "cytosol",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P35235-2"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9645128",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9645128"
                }
            ]
        },
        {
            "id": "R-MMU-9645133",
            "name": "p-Stat5 dissociates from activator:Stat5 complex",
            "equation": "",
            "summary": "Signal transducer and activator of transcription (Stat5a/Stat5b) is activated by a range of upstream signals including cytokines and growth factors. Activators bind and phosphorylate Stat5 following which Stat5 is released from the complex and translocates to the nucleus to regulate gene transcription (Sarah C et al, 2013).",
            "cellular_location": "cytosol",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P35235-2"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9645133",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9645133"
                }
            ]
        },
        {
            "id": "R-MMU-9645136",
            "name": "Activator phosphorylates Stat5",
            "equation": "",
            "summary": "Signal transducer and activator of transcription (Stat5a/Stat5b) is regulated by extracellular factors including cytokines and growth factors. Activators bind and phosphorylate Stat5 which results in its activation (Sarah C et al, 2013).",
            "cellular_location": "cytosol",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P35235-2"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9645136",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9645136"
                }
            ]
        },
        {
            "id": "R-MMU-9698170",
            "name": "Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P42337-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9698170",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9698170"
                }
            ]
        },
        {
            "id": "R-MMU-9698408",
            "name": "PTPRJ dephosphorylates active FLT3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q64455-1",
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9698408",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9698408"
                }
            ]
        },
        {
            "id": "R-MMU-9699578",
            "name": "Active FLT3 phosphorylates CDKN1B",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [
                "R-MMU-8848438"
            ],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9699578",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9699578"
                }
            ]
        },
        {
            "id": "R-MMU-9706287",
            "name": "Active FLT3 binds to ABL2",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "Q4JIM5-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706287",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706287"
                }
            ]
        },
        {
            "id": "R-MMU-9706293",
            "name": "Active FLT3 binds to CBL",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P22682-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706293",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706293"
                }
            ]
        },
        {
            "id": "R-MMU-9706298",
            "name": "Active FLT3 binds to CSK",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P41241-1",
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706298",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706298"
                }
            ]
        },
        {
            "id": "R-MMU-9706304",
            "name": "Active FLT3 binds to GRAP2",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706304",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706304"
                }
            ]
        },
        {
            "id": "R-MMU-9706308",
            "name": "Active FLT3 binds to GRB10",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706308",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706308"
                }
            ]
        },
        {
            "id": "R-MMU-9706312",
            "name": "Active FLT3 binds to LCK",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P06240-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706312",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706312"
                }
            ]
        },
        {
            "id": "R-MMU-9706315",
            "name": "Active FLT3 binds to SH2B3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706315",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706315"
                }
            ]
        },
        {
            "id": "R-MMU-9706319",
            "name": "Active FLT3 binds to SLA",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706319",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706319"
                }
            ]
        },
        {
            "id": "R-MMU-9706323",
            "name": "Active FLT3 binds to SLA2",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706323",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706323"
                }
            ]
        },
        {
            "id": "R-MMU-9706328",
            "name": "Active FLT3 binds to SOCS2",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706328",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706328"
                }
            ]
        },
        {
            "id": "R-MMU-9706330",
            "name": "Active FLT3 binds to SOCS6",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706330",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706330"
                }
            ]
        },
        {
            "id": "R-MMU-9706336",
            "name": "Active FLT3 binds to SYK",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P48025-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706336",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706336"
                }
            ]
        },
        {
            "id": "R-MMU-9706340",
            "name": "Active FLT3:p-Y-GRB10 binds PIK3R1",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706340",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706340"
                }
            ]
        },
        {
            "id": "R-MMU-9706344",
            "name": "FLT3 phosphorylates GRB10",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706344",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706344"
                }
            ]
        },
        {
            "id": "R-MMU-9706345",
            "name": "Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P42337-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706345",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706345"
                }
            ]
        },
        {
            "id": "R-MMU-9706350",
            "name": "FLT3 phosphorylates CBL",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P22682-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706350",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706350"
                }
            ]
        },
        {
            "id": "R-MMU-9706354",
            "name": "Ubiquitination of FLT3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1",
                "P22682-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706354",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706354"
                }
            ]
        },
        {
            "id": "R-MMU-9706364",
            "name": "Internalization of ubiquitinated FLT3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "endosome membrane, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q00342-1"
            ],
            "evidence": [
                {
                    "id": "R-MMU-9706364",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9706364"
                }
            ]
        }
    ],
    "reaction_participants": [
        {
            "participant_id": "R-ALL-179838",
            "participant_name": "PI(3,4,5)P3 [plasma membrane]",
            "crossref": [
                {
                    "id": "C05981",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "57836",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05981",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "57836",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05981",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "57836",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05981",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "57836",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05981",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "57836",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "C05981",
                    "database": "COMPOUND",
                    "url": ""
                },
                {
                    "id": "57836",
                    "database": "ChEBI",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-MMU-8848438",
            "participant_name": "phospho-Cdkn1b [cytosol]",
            "crossref": [
                {
                    "id": "P46414",
                    "database": "UniProt",
                    "url": ""
                },
                {
                    "id": "ENSMUST00000003115",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "ENSMUST00000204807",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "P46414",
                    "database": "PRO",
                    "url": ""
                },
                {
                    "id": "NP_034005.2",
                    "database": "RefSeq",
                    "url": ""
                },
                {
                    "id": "ENSMUSP00000145056",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "ENSMUSP00000065832",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "ENSMUSG00000003031",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "104565",
                    "database": "MGI",
                    "url": ""
                },
                {
                    "id": "ENSMUSP00000003115",
                    "database": "Ensembl",
                    "url": ""
                },
                {
                    "id": "ENSMUST00000067327",
                    "database": "Ensembl",
                    "url": ""
                }
            ]
        }
    ],
    "reaction_enzymes": [
        {
            "uniprot_ac": "A0A0G2JW59",
            "gene_name": "Flt3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0G2JW59",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JW59"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2JW59",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JW59"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A0G2K6M9",
            "gene_name": "Btk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0G2K6M9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K6M9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2K6M9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K6M9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A0R4J8U1",
            "gene_name": "Zap70",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0R4J8U1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0R4J8U1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0R4J8U1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0R4J8U1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I5ZP97",
            "gene_name": "Dyrk1b",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I5ZP97",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I5ZP97",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I5ZVE3",
            "gene_name": "Ephb3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I5ZVE3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZVE3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I5ZVE3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZVE3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6A5T6",
            "gene_name": "Mst1r",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6A5T6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6A5T6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6A5T6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6A5T6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6AM23",
            "gene_name": "Jak1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6AM23",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AM23"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6AM23",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AM23"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6AWX7",
            "gene_name": "Dyrk4",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6AWX7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6AWX7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6GCV6",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6GCV6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6GCV6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6GCV6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6GCV6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B1WC09",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "B1WC09",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B1WC09"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B1WC09",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B1WC09"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B2RYC7",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "B2RYC7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RYC7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B2RYC7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RYC7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B5DFD6",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "B5DFD6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B5DFD6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B5DFD6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B5DFD6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZBN3",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZBN3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZBN3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZBN3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZBN3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZCD0",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZCD0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZCD0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "D3ZCD0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZCD0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZD03",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZD03",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZD03"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "D3ZD03",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZD03"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZDH4",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZDH4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDH4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "D3ZDH4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDH4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZDS3",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZDS3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDS3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "D3ZDS3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDS3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZZK3",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZZK3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZZK3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "D3ZZK3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZZK3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4A584",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D4A584",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A584"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "D4A584",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A584"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4A7W7",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D4A7W7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A7W7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "D4A7W7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A7W7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4ADZ5",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D4ADZ5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ADZ5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D4ADZ5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ADZ5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "E9PSY0",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "E9PSY0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PSY0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "E9PSY0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PSY0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "E9PT20",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "E9PT20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PT20"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "E9PT20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PT20"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LM93",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LM93",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LM93"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LM93",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LM93"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LRZ0",
            "gene_name": "Alk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LRZ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LRZ0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LRZ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LRZ0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LSG7",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LSG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSG7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LSG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSG7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LSN4",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LSN4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSN4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LSN4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSN4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LVI0",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LVI0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LVI0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LVI0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LVI0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LYY7",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LYY7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LYY7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LYY7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LYY7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1M0N1",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1M0N1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1M0N1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1M0N1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1M0N1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1MAJ0",
            "gene_name": "Ephb2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1MAJ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1MAJ0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1MAJ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1MAJ0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V6K6",
            "gene_name": "Egfr",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V6K6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V6K6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V6K6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V6K6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V783",
            "gene_name": "Ripk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V9H8",
            "gene_name": "Ret",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V9H8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V9H8"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V9H8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V9H8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "M0RDA4",
            "gene_name": "Ephb4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "M0RDA4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/M0RDA4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "M0RDA4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/M0RDA4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O08680",
            "gene_name": "Epha3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O08680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08680"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O08680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08680"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O08775",
            "gene_name": "Kdr",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O08775",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08775"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O08775",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08775"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O09110",
            "gene_name": "Map2k3",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O09110",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09110"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O09110",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09110"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O09127",
            "gene_name": "Epha8",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O09127",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09127"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O09127",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09127"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O14733",
            "gene_name": "MAP2K7",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O14733",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O14733"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O14733",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O14733"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O15146",
            "gene_name": "MUSK",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O15146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O15146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O15146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O15146"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35082",
            "gene_name": "Kl",
            "activity": [
                {
                    "ec_number": "3.2.1.31",
                    "activity": "a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate.",
                    "evidence": [
                        {
                            "id": "O35082",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35082"
                        }
                    ]
                },
                {
                    "ec_number": "3.2.1.31",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35082",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35082"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35346",
            "gene_name": "Ptk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O35346",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35346"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35346",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35346"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35491",
            "gene_name": "Clk2",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O35491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35491"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35491"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35492",
            "gene_name": "Clk3",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O35492",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35492"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35492",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35492"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35493",
            "gene_name": "Clk4",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O35493",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35493"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35493",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35493"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35904",
            "gene_name": "Pik3cd",
            "activity": [
                {
                    "ec_number": "2.7.1.153",
                    "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).",
                    "evidence": [
                        {
                            "id": "O35904",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35904"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.153",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35904",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35904"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.137",
                    "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).",
                    "evidence": [
                        {
                            "id": "O35904",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35904"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.137",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35904",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35904"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O43353",
            "gene_name": "RIPK2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O43353",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43353"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O43353",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43353"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O43353",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43353"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O43781",
            "gene_name": "DYRK3",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O43781",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43781"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O43781",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43781"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O54804",
            "gene_name": "Chka",
            "activity": [
                {
                    "ec_number": "2.7.1.32",
                    "activity": "ATP + choline = ADP + H(+) + phosphocholine.",
                    "evidence": [
                        {
                            "id": "O54804",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54804"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.82",
                    "activity": "ATP + ethanolamine = ADP + H(+) + phosphoethanolamine.",
                    "evidence": [
                        {
                            "id": "O54804",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54804"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.32",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O54804",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54804"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O54967",
            "gene_name": "Tnk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O54967",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54967"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O54967",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54967"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O54967",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54967"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O54967",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54967"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O60674",
            "gene_name": "JAK2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O60674",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O60674"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O60674",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O60674"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O70146",
            "gene_name": "Tesk1",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O70146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O70146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O70146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O70146"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O75716",
            "gene_name": "STK16",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O75716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O75716"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O75716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O75716"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O75716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O75716"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O88697",
            "gene_name": "Stk16",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O88697",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O88697"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O88697",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O88697"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O88697",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O88697"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P00519",
            "gene_name": "ABL1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P00519",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00519"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P00519",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00519"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P00520",
            "gene_name": "Abl1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P00520",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00520"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P00520",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00520"
                        }
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                            "url": "https://www.uniprot.org/uniprot/P00522"
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P00528",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P00528",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P00528"
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                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P00533",
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                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P00533",
                            "database": "UniProtKB",
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P04412",
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                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                            "id": "P04412",
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                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P04626",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04626"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P04626",
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                            "url": "https://www.uniprot.org/uniprot/P04626"
                        }
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P04629",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04629"
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P04629",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P05480",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05480"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "P05480",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05480"
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                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P05532",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05532"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P05532",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05532"
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                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P05622",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P05622"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P05622",
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P06213",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P06213"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P06213",
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                            "url": "https://www.uniprot.org/uniprot/P06213"
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                }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P06239",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P06239"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "P06239",
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                            "url": "https://www.uniprot.org/uniprot/P06239"
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                }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P06240",
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                            "url": "https://www.uniprot.org/uniprot/P06240"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P06240",
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P06241",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P06241",
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        {
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                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P06494",
                            "database": "UniProtKB",
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                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P06494",
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                            "url": "https://www.uniprot.org/uniprot/P06494"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P06784",
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                    ]
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P06784",
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P07332",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P07332",
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P07333",
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P07333",
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                    ]
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P07947",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P07947",
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                    "ec_number": "2.7.10.2",
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                            "id": "P07948",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P07948",
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                    "ec_number": "2.7.10.1",
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                            "id": "P07949",
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P07949",
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                    "ec_number": "2.7.12.2",
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                            "id": "P08018",
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                    ]
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P08018",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08069",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P08069",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08103",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P08103",
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                    "ec_number": "3.6.5.2",
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                            "id": "P08556",
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                {
                    "ec_number": "3.6.5.2",
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                            "id": "P08556",
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                    "ec_number": "2.7.10.1",
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                            "id": "P08581",
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P08581",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08630",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P08630",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08631",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08631"
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P08631",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P08922",
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P08922",
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                }
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P08923",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08923"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P08923",
                            "database": "UniProtKB",
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                    ]
                }
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        {
            "uniprot_ac": "P09208",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "P09208",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09208"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P09208",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09208"
                        }
                    ]
                }
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        {
            "uniprot_ac": "P09215",
            "gene_name": "Prkcd",
            "activity": [
                {
                    "ec_number": "2.7.11.13",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P09215",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09215"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09215",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09215"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09581",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09581",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09581"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09619",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09619",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09619"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09619",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09619"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09759",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09759",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09759"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09759",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09759"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09760",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09760"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09760"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09769",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09769",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09769"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09769",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09769"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P0C1S8",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P0C1S8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P0C1S8"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P0C1S8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P0C1S8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P10721",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P10721",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P10721"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P10721",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P10721"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P11362",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P11362",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11362"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P11362",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11362"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P11798",
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                {
                    "ec_number": "2.7.11.17",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                        {
                            "id": "P11798",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11798"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.17",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P11798",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11798"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P11980",
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                {
                    "ec_number": "2.7.1.40",
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                        {
                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.40",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P12931",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P12931"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P12931",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P12931"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P13368",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P13368"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P13368",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P13368"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "P14234",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P14234",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14234"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P14234",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14234"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P14616",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P14616",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14616"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P14616",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14616"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P14618",
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                {
                    "ec_number": "2.7.1.40",
                    "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.",
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                        {
                            "id": "P14618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14618"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.40",
                    "activity": "",
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                        {
                            "id": "P14618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14618"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P14618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14618"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P14618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14618"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P14680",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                        {
                            "id": "P14680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14680"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P14680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14680"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P14719",
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                {
                    "ec_number": "3.2.2.6",
                    "activity": "H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide.",
                    "evidence": [
                        {
                            "id": "P14719",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14719"
                        }
                    ]
                },
                {
                    "ec_number": "3.2.2.6",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P14719",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14719"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P15127",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P15127",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P15127"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P15127",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P15127"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P15208",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P15208"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P15208",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P15208"
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                    ]
                }
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        {
            "uniprot_ac": "P15209",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P15209",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P15209"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P15209",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P15209"
                        }
                    ]
                }
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        },
        {
            "uniprot_ac": "P16056",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P16056",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16056"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                            "id": "P16056",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16056"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P16092",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P16092",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16092"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P16092",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16092"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P16234",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P16234",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16234"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P16234",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16234"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P16277",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P16277",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16277"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P16277",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16277"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P16591",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P16591",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16591"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P16591",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16591"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P16879",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P16879",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16879"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P16879",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P16879"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P17948",
            "gene_name": "FLT1",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P17948",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P17948"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P17948",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P17948"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P18052",
            "gene_name": "Ptpra",
            "activity": [
                {
                    "ec_number": "3.1.3.48",
                    "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.",
                    "evidence": [
                        {
                            "id": "P18052",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18052"
                        }
                    ]
                },
                {
                    "ec_number": "3.1.3.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P18052",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18052"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P18106",
            "gene_name": "FER",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P18106",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18106"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P18106",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18106"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P18160",
            "gene_name": "splA",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P18160",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18160"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P18160",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18160"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P18161",
            "gene_name": "splB",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P18161",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18161"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P18161",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18161"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P18475",
            "gene_name": "tor",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P18475",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18475"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P18475",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P18475"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P19525",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P19525",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P19525"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P19525",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P19525"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P19525",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P19525"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P20786",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P20786",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P20786"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P20786",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P20786"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P21709",
            "gene_name": "EPHA1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P21709",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21709"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P21709",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21709"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P21802",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P21802",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21802"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P21802",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21802"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P21803",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P21803",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21803"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P21803",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21803"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P21860",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P21860",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21860"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P21860",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21860"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P21965",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P21965",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21965"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P21965",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21965"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P22216",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P22216",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22216"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P22216",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22216"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P22455",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P22455",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22455"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P22455",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22455"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P22518",
            "gene_name": "Clk1",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P22518",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22518"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P22518",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22518"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P22607",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P22607",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22607"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P22607",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22607"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P22682",
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            "activity": [
                {
                    "ec_number": "2.3.2.27",
                    "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.",
                    "evidence": [
                        {
                            "id": "P22682",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22682"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.2.27",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P22682",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P22682"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P23458",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P23458",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P23458"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P23458",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P23458"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P24062",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P24062",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24062"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P24062",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24062"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P24604",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P24604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24604"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P24604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24604"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P25911",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P25911",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P25911"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P25911",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P25911"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P26618",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P26618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P26618"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P26618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P26618"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P28652",
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                {
                    "ec_number": "2.7.11.17",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P28652",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P28652"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.17",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P28652",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P28652"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P28867",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P28867",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P28867"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P28867",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P28867"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P28867",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P28867"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P29317",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P29317",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29317"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P29317",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29317"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P29319",
            "gene_name": "Epha3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P29319",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29319"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P29319",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29319"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P29320",
            "gene_name": "EPHA3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P29320",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29320"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P29320",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29320"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P29321",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P29321",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29321"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P29321",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29321"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P29322",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P29322",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29322"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P29322",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29322"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P29323",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P29323",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29323"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P29323",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29323"
                        }
                    ]
                }
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        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P29376",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29376"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P29376",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29376"
                        }
                    ]
                }
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        },
        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P29597",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29597"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "id": "P29597",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29597"
                        }
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                }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P30291",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P30291"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P30291",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P30291"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P30530",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P30530"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P30530",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P30530"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P31938",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P31938"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
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                        {
                            "id": "P31938",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P31938"
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                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P32350",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32350"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P32350",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32350"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "P32490",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                        {
                            "id": "P32490",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32490"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
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                        {
                            "id": "P32490",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32490"
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                    ]
                }
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        {
            "uniprot_ac": "P32491",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                        {
                            "id": "P32491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32491"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
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                        {
                            "id": "P32491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32491"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P32577",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32577"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P32577",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32577"
                        }
                    ]
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        {
            "uniprot_ac": "P32883",
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                {
                    "ec_number": "3.6.5.2",
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                        {
                            "id": "P32883",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32883"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.5.2",
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                        {
                            "id": "P32883",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P32883"
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                }
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P33981",
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                            "url": "https://www.uniprot.org/uniprot/P33981"
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                    ]
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
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                        {
                            "id": "P33981",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P33981"
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                }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P34152",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34152"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P34152",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34152"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P34925",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34925"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P34925",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34925"
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                    ]
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            ]
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                {
                    "ec_number": "3.1.3.48",
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                    "evidence": [
                        {
                            "id": "P35235",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35235"
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                    ]
                },
                {
                    "ec_number": "3.1.3.48",
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                        {
                            "id": "P35235",
                            "database": "UniProtKB",
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P35546",
                            "database": "UniProtKB",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P35546",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35546"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P35590",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35590"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P35590",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35590"
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                    ]
                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P35739",
                            "database": "UniProtKB",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P35739",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35739"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                        {
                            "id": "P35761",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35761"
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                    ]
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                {
                    "ec_number": "2.7.12.1",
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                            "id": "P35761",
                            "database": "UniProtKB",
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                    ]
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        {
            "uniprot_ac": "P35790",
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                {
                    "ec_number": "2.7.1.32",
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                            "id": "P35790",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35790"
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                    ]
                },
                {
                    "ec_number": "2.7.1.82",
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                        {
                            "id": "P35790",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.7.1.32",
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                            "id": "P35790",
                            "database": "UniProtKB",
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                    ]
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            "uniprot_ac": "P35916",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P35916",
                            "database": "UniProtKB",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P35916",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35916"
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                    ]
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P35917",
                            "database": "UniProtKB",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P35917",
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                    ]
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P35918",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P35918",
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                    ]
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            "uniprot_ac": "P35968",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P35968",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35968"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P35968",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35968"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P35969",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P35969",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35969"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P35969",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35969"
                        }
                    ]
                }
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        },
        {
            "uniprot_ac": "P35991",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P35991",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35991"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "id": "P35991",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35991"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P36506",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P36506",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P36506"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
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                            "id": "P36506",
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                            "url": "https://www.uniprot.org/uniprot/P36506"
                        }
                    ]
                }
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P36507",
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                    ]
                },
                {
                    "ec_number": "2.7.12.2",
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                        {
                            "id": "P36507",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P36507"
                        }
                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
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                    "evidence": [
                        {
                            "id": "P36888",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P36888"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P36888",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P36888"
                        }
                    ]
                }
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P39688",
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                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P39688",
                            "database": "UniProtKB",
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                }
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                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P41240",
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                            "url": "https://www.uniprot.org/uniprot/P41240"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P41240",
                            "database": "UniProtKB",
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        {
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                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P41241",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P41241"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P41241",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P41241"
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                    ]
                }
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        },
        {
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                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P41242",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P41242"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P41242",
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                    ]
                }
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P41243",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P41243"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P41243",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P41243"
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                    ]
                }
            ]
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                {
                    "ec_number": "2.7.11.1",
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                        {
                            "id": "P42337",
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                            "url": "https://www.uniprot.org/uniprot/P42337"
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                    ]
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                {
                    "ec_number": "2.7.1.153",
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                        {
                            "id": "P42337",
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                {
                    "ec_number": "2.7.1.137",
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                        {
                            "id": "P42337",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.7.1.153",
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                        {
                            "id": "P42337",
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                        }
                    ]
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                {
                    "ec_number": "2.7.1.137",
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                        {
                            "id": "P42337",
                            "database": "UniProtKB",
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                    "ec_number": "2.7.10.2",
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                            "id": "P42679",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42679",
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                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P42680",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P42680",
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                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P42681",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P42681",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42682",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42682",
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                {
                    "ec_number": "2.7.10.2",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42684",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42685",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42685",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P43403",
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                    "ec_number": "2.7.10.2",
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                            "id": "P43403",
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                    "ec_number": "2.7.10.2",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P43404",
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                    "ec_number": "2.7.10.2",
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                            "id": "P43405",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P43405",
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P45985",
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                    ]
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P45985",
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                    "ec_number": "2.7.12.2",
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                            "id": "P46734",
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P46734",
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                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P47809",
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                    ]
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P47809",
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                    "ec_number": "2.7.10.2",
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                            "id": "P47810",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P47810",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P48025",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P48025"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P48025",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P48025"
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                    ]
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            ]
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        {
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                        {
                            "id": "P49657",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49657"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
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                            "id": "P49657",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49657"
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                    ]
                }
            ]
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        {
            "uniprot_ac": "P49759",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P49759",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49759"
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                    ]
                },
                {
                    "ec_number": "2.7.12.1",
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                            "id": "P49759",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49759"
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                    ]
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        },
        {
            "uniprot_ac": "P49760",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P49760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49760"
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                    ]
                },
                {
                    "ec_number": "2.7.12.1",
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                        {
                            "id": "P49760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49760"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P49761",
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P49761",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49761"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P49761",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49761"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P49762",
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                {
                    "ec_number": "2.7.11.-",
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                            "id": "P49762",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49762"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P49762",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49762"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
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                        {
                            "id": "P49762",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49762"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "P50545",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P50545"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P50545",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P50545"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P51451",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P51451"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P51451",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P51451"
                        }
                    ]
                }
            ]
        },
        {
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            "gene_name": "BMX",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P51813",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P51813"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P51813",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P51813"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P52332",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52332"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P52332",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52332"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P52333",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52333"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P52333",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52333"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.1.40",
                    "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.",
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                        {
                            "id": "P52480",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52480"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.40",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P52480",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52480"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P52480",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52480"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P52480",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52480"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P52564",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P52564",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52564"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P52564",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P52564"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P53767",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P53767",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P53767"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P53767",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P53767"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54199",
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P54199",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54199"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54199",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54199"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54350",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54350"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "P54350",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54350"
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                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P54753",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54753"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P54753",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54753"
                        }
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                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P54754",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54754"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P54754",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54754"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54756",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54756"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P54756",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54756"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54757",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54757"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P54757",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54757"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54758",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54758",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54758"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54758",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54758"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54759",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54759",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54759"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54759",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54759"
                        }
                    ]
                }
            ]
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        {
            "uniprot_ac": "P54760",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54760"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54760"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54761",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54761",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54761"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54761",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54761"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54762",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54762",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54762"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P54762",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54762"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54763",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54763",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54763"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54763",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54763"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54764",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P54764",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54764"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P54764",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54764"
                        }
                    ]
                }
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        },
        {
            "uniprot_ac": "P55144",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P55144",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55144"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P55144",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55144"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P55146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P55146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55146"
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                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P57097",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57097"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                            "id": "P57097",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57097"
                        }
                    ]
                }
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        },
        {
            "uniprot_ac": "P57760",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P57760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57760"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P57760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57760"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
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                            "id": "P57760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57760"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P58801",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P58801",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P58801"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P58801",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P58801"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P58801",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P58801"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P63001",
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            "activity": [
                {
                    "ec_number": "3.6.5.2",
                    "activity": "GTP + H2O = GDP + H(+) + phosphate.",
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                        {
                            "id": "P63001",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P63001"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.5.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P63001",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P63001"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70196",
            "gene_name": "Traf6",
            "activity": [
                {
                    "ec_number": "2.3.2.27",
                    "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.",
                    "evidence": [
                        {
                            "id": "P70196",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70196"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.2.27",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70196",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70196"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70236",
            "gene_name": "Map2k6",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P70236",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70236"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70236",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70236"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70424",
            "gene_name": "Erbb2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P70424",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70424"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70424",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70424"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70451",
            "gene_name": "Fer",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P70451",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70451"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70451",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70451"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70600",
            "gene_name": "Ptk2b",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P70600",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70600"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70600",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70600"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P83102",
            "gene_name": "Dyrk3",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P83102",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P83102"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P83102",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P83102"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P97504",
            "gene_name": "Bmx",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P97504",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97504"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P97504",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97504"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P97523",
            "gene_name": "Met",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P97523",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97523"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P97523",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97523"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P97793",
            "gene_name": "Alk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P97793",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97793"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P97793",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97793"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00342",
            "gene_name": "Flt3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00342",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00342"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00342",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00342"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00495",
            "gene_name": "Csf1r",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00495",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00495"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00495",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00495"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00993",
            "gene_name": "Axl",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00993",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00993"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00993",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00993"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01134",
            "gene_name": "Chka",
            "activity": [
                {
                    "ec_number": "2.7.1.32",
                    "activity": "ATP + choline = ADP + H(+) + phosphocholine.",
                    "evidence": [
                        {
                            "id": "Q01134",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01134"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.82",
                    "activity": "ATP + ethanolamine = ADP + H(+) + phosphoethanolamine.",
                    "evidence": [
                        {
                            "id": "Q01134",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01134"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.32",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01134",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01134"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01279",
            "gene_name": "Egfr",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01279",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01279"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01279",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01279"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01621",
            "gene_name": "Lck",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01621",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01621"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01621",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01621"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01887",
            "gene_name": "Ryk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01887",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01887"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01887",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01887"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01974",
            "gene_name": "ROR2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01974",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01974"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01974",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01974"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01986",
            "gene_name": "Map2k1",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01986",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01986"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01986",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01986"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q02750",
            "gene_name": "MAP2K1",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q02750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02750"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q02750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02750"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q02763",
            "gene_name": "TEK",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q02763",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02763"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q02763",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02763"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q02858",
            "gene_name": "Tek",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q02858",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02858"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q02858",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02858"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03137",
            "gene_name": "Epha4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03137"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03137"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03142",
            "gene_name": "Fgfr4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03142",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03142"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03142",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03142"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03145",
            "gene_name": "Epha2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03145",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03145"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03145",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03145"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03146",
            "gene_name": "Ddr1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03146"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03351",
            "gene_name": "Ntrk3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03351",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03351"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03351",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03351"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03526",
            "gene_name": "Itk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03526"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03526"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03963",
            "gene_name": "Eif2ak2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03963",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03963"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03963",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03963"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03963",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03963"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q04589",
            "gene_name": "Fgfr1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "Q04589",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04589"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                            "id": "Q04589",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04589"
                        }
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "Q04736",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04736"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "Q04736",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04736"
                        }
                    ]
                }
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            "uniprot_ac": "Q04912",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q04912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04912"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q04912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04912"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q05030",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05030"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q05030",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05030"
                        }
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                }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "Q05397",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05397"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "Q05397",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05397"
                        }
                    ]
                }
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q05655",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05655"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q05655",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05655"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "",
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                        {
                            "id": "Q05655",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05655"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q06187",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "Q06187",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06187"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "Q06187",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06187"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q06418",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "Q06418",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06418"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q06418",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06418"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q06806",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q06806",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06806"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q06806",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06806"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q07014",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q07014",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07014"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q07014",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07014"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q07407",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07407"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q07407",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07407"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q07912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07912"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                        {
                            "id": "Q07912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07912"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
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                        {
                            "id": "Q07912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07912"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
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                        {
                            "id": "Q07912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07912"
                        }
                    ]
                }
            ]
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q08345",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08345"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "Q08345",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08345"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "Q08881",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08881"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "Q08881",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08881"
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q09147",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q09147"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q09147",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q09147"
                        }
                    ]
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            ]
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q12866",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q12866"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q12866",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q12866"
                        }
                    ]
                }
            ]
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        {
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                        {
                            "id": "Q13163",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13163"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
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                        {
                            "id": "Q13163",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13163"
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                    ]
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        {
            "uniprot_ac": "Q13470",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "Q13470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "id": "Q13470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13470"
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                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
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                            "id": "Q13627",
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                            "url": "https://www.uniprot.org/uniprot/Q13627"
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                    ]
                },
                {
                    "ec_number": "2.7.11.23",
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                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
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                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
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                    ]
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        {
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q13882",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13882"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q13882",
                            "database": "UniProtKB",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "Q14289",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14289"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q14289",
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                            "url": "https://www.uniprot.org/uniprot/Q14289"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q14680",
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                            "url": "https://www.uniprot.org/uniprot/Q14680"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
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                            "id": "Q14680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14680"
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                    ]
                },
                {
                    "ec_number": "2.7.11.1",
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                            "id": "Q14680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14680"
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "Q15303",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15303"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q15303",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15303"
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        {
            "uniprot_ac": "Q15375",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q15375",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15375"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q15375",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15375"
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                    ]
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            "uniprot_ac": "Q15569",
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q15569",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15569"
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                    ]
                },
                {
                    "ec_number": "2.7.12.1",
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                            "id": "Q15569",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15569"
                        }
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            "uniprot_ac": "Q16288",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "Q16288",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16288"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "Q16288",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16288"
                        }
                    ]
                }
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        },
        {
            "uniprot_ac": "Q16620",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "Q16620",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16620"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                            "id": "Q16620",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16620"
                        }
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                {
                    "ec_number": "2.7.10.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16832"
                        }
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                {
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q16832"
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q23977",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q23977"
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                    ]
                },
                {
                    "ec_number": "2.7.12.2",
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                            "id": "Q23977",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q23977"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.-",
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                            "id": "Q23977",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q23977"
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "Q24145",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24145"
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q24145",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24145"
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "url": "https://www.uniprot.org/uniprot/Q24324"
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "Q24324",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24324"
                        }
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                {
                    "ec_number": "2.7.11.-",
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                            "id": "Q24324",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24324"
                        }
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q24488",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24488"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q24488",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24488"
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24592"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q24592",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q24592"
                        }
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q27324",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q27324"
                        }
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q27324",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q27324"
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q3UFB7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3UFB7"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q3UFB7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3UFB7"
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                    "ec_number": "2.7.10.1",
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                            "id": "Q498D6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q498D6"
                        }
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "Q498D6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q498D6"
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q4JIM5",
                            "database": "UniProtKB",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q4JIM5",
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                    "ec_number": "2.7.10.2",
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                            "id": "Q4KM97",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q4KSH7",
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "Q4V8A3",
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                {
                    "ec_number": "2.7.12.1",
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                    "ec_number": "2.7.10.2",
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                            "id": "Q501W1",
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                            "url": "https://www.uniprot.org/uniprot/Q501W1"
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q501W1",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q504Y2",
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                            "url": "https://www.uniprot.org/uniprot/Q504Y2"
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "Q504Y2",
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q54BC9",
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                            "url": "https://www.uniprot.org/uniprot/Q54BC9"
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                {
                    "ec_number": "2.7.12.1",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q54G28",
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                {
                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.12.1",
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                            "id": "Q54I36",
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                {
                    "ec_number": "2.7.12.1",
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                    "ec_number": "2.7.10.1",
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                            "id": "Q54N73",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                    "ec_number": "2.7.12.1",
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                            "id": "Q54R58",
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                {
                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.12.1",
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                {
                    "ec_number": "2.7.12.1",
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                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q55CL6",
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                {
                    "ec_number": "2.7.12.2",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q5FVG7",
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                {
                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q5U2X5",
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                {
                    "ec_number": "2.7.10.2",
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                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q5U2X5",
                            "database": "UniProtKB",
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                    ]
                },
                {
                    "ec_number": "2.7.11.1",
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                    "evidence": [
                        {
                            "id": "Q5U2X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U2X5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5U4C9",
            "gene_name": "Dyrk2",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5U4C9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U4C9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5U4C9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U4C9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60629",
            "gene_name": "Epha5",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60629",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60629"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q60629",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60629"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60750",
            "gene_name": "Epha1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60750"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q60750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60750"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60751",
            "gene_name": "Igf1r",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60751",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60751"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q60751",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60751"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60805",
            "gene_name": "Mertk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60805",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60805"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q60805",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60805"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61006",
            "gene_name": "Musk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61006",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61006"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61006",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61006"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61214",
            "gene_name": "Dyrk1a",
            "activity": [
                {
                    "ec_number": "2.7.11.23",
                    "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].",
                    "evidence": [
                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61411",
            "gene_name": "Hras",
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                {
                    "ec_number": "3.6.5.2",
                    "activity": "GTP + H2O = GDP + H(+) + phosphate.",
                    "evidence": [
                        {
                            "id": "Q61411",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61411"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.5.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61411",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61411"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61526",
            "gene_name": "Erbb3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61526"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61526"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61527",
            "gene_name": "Erbb4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61527",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61527"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61527",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61527"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61730",
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            "activity": [
                {
                    "ec_number": "3.2.2.6",
                    "activity": "H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide.",
                    "evidence": [
                        {
                            "id": "Q61730",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61730"
                        }
                    ]
                },
                {
                    "ec_number": "3.2.2.6",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61730",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61730"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61772",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61772",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61772"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61772",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61772"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61846",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61846",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61846"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61846",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61846"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61846",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61846"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61851",
            "gene_name": "Fgfr3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61851",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61851"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61851",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61851"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62120",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62120",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62120"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62120",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62120"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62137",
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            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62137"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62137"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62190",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62190",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62190"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62190",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62190"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62270",
            "gene_name": "Srms",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62270",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62270"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62270",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62270"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62371",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62371",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62371"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62371",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62371"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62406",
            "gene_name": "Irak1",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62406",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62406"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62406",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62406"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62413",
            "gene_name": "Epha6",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62413",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62413"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62413",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62413"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62662",
            "gene_name": "Frk",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62662",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62662"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62662",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62662"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62689",
            "gene_name": "Jak2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62689",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62689"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62689",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62689"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62799",
            "gene_name": "Erbb3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62799",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62799"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62799",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62799"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62838",
            "gene_name": "Musk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62838",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62838"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62838",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62838"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62844",
            "gene_name": "Fyn",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62844",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62844"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62844",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62844"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62862",
            "gene_name": "Map2k5",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62862",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62862"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62862",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62862"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62956",
            "gene_name": "Erbb4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62956",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62956"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62956",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62956"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63116",
            "gene_name": "Kit",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63116",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63116"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63116",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63116"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63117",
            "gene_name": "Clk3",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63117",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63117"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63117",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63117"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63132",
            "gene_name": "Ros1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63132",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63132"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63132",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63132"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63184",
            "gene_name": "Eif2ak2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63184",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63184"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63184",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63184"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63184",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63184"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63272",
            "gene_name": "Jak3",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63272",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63272"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63272",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63272"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63470",
            "gene_name": "Dyrk1a",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63474",
            "gene_name": "Ddr1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63474",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63474"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63474",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63474"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63572",
            "gene_name": "Tesk1",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63572",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63572"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63572",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63572"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63604",
            "gene_name": "Ntrk2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63604"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63604"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63802",
            "gene_name": "Wee1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63802",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63802"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63802",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63802"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63932",
            "gene_name": "Map2k2",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63932",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63932"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63932",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63932"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64434",
            "gene_name": "Ptk6",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q64434",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64434"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64434",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64434"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64455",
            "gene_name": "Ptprj",
            "activity": [
                {
                    "ec_number": "3.1.3.48",
                    "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.",
                    "evidence": [
                        {
                            "id": "Q64455",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64455"
                        }
                    ]
                },
                {
                    "ec_number": "3.1.3.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64455",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64455"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64716",
            "gene_name": "Insrr",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q64716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64716"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64716"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64725",
            "gene_name": "Syk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q64725",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64725"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64725",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64725"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q66JT0",
            "gene_name": "Wee2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q66JT0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q66JT0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q66JT0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q66JT0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6J9G0",
            "gene_name": "STYK1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6J9G0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6J9G0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6J9G1",
            "gene_name": "Styk1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6J9G1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6J9G1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6P6U0",
            "gene_name": "Fgr",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6P6U0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6P6U0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6P6U0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6P6U0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6PF93",
            "gene_name": "Pik3c3",
            "activity": [
                {
                    "ec_number": "2.7.1.137",
                    "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).",
                    "evidence": [
                        {
                            "id": "Q6PF93",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6PF93"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.137",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6PF93",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6PF93"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6PHZ2",
            "gene_name": "Camk2d",
            "activity": [
                {
                    "ec_number": "2.7.11.17",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6PHZ2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6PHZ2"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.17",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6PHZ2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6PHZ2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6VNS1",
            "gene_name": "Ntrk3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6VNS1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6VNS1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6VNS1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6VNS1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6XUX1",
            "gene_name": "Dstyk",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6XUX1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6XUX1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6XUX2",
            "gene_name": "Dstyk",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6XUX2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX2"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6XUX2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6XUX3",
            "gene_name": "DSTYK",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6XUX3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6XUX3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q75JK0",
            "gene_name": "zakA",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q75JK0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q75JK0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q75JK0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q75JK0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q76NV1",
            "gene_name": "dyrk1",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q76NV1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q76NV1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q76NV1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q76NV1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q78DX7",
            "gene_name": "Ros1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q78DX7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q78DX7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q78DX7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q78DX7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q7KJ08",
            "gene_name": "Alk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q7KJ08",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q7KJ08"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q7KJ08",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q7KJ08"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8BI55",
            "gene_name": "Dyrk4",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q8BI55",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BI55"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8BI55",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BI55"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8BTI9",
            "gene_name": "Pik3cb",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q8BTI9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BTI9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.153",
                    "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).",
                    "evidence": [
                        {
                            "id": "Q8BTI9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BTI9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.153",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8BTI9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BTI9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8BYG9",
            "gene_name": "Epha10",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q8BYG9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BYG9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8BYG9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BYG9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8CBF3",
            "gene_name": "Ephb1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q8CBF3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8CBF3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CBF3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8CE90",
            "gene_name": "Map2k7",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q8CE90",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CE90"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8CE90",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CE90"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8INJ8",
            "gene_name": "Csk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q8INJ8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8INJ8"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8INJ8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8INJ8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8R4K2",
            "gene_name": "Irak4",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q8R4K2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8R4K2"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8R4K2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8R4K2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8VCT9",
            "gene_name": "Tesk2",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q8VCT9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8VCT9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8VCT9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8VCT9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8VD65",
            "gene_name": "Pik3r4",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q8VD65",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8VD65"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8VD65",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8VD65"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q91ZT1",
            "gene_name": "Flt4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q91ZT1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q91ZT1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q91ZT1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q91ZT1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q922K9",
            "gene_name": "Frk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q922K9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q922K9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q922K9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q922K9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q922Y0",
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            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q922Y0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q922Y0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q922Y0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q922Y0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q923T9",
            "gene_name": "Camk2g",
            "activity": [
                {
                    "ec_number": "2.7.11.17",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q923T9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q923T9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.17",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q923T9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q923T9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q924U5",
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            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q924U5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q924U5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q924U5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q924U5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q92630",
            "gene_name": "DYRK2",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q92630",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92630"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q92630",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92630"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q96KB5",
            "gene_name": "PBK",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q96KB5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q96KB5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q96KB5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q96KB5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q96S53",
            "gene_name": "TESK2",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q96S53",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q96S53"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q96S53",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q96S53"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q99ML2",
            "gene_name": "Tnk1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q99ML2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q99ML2"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q99ML2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q99ML2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9H3Y6",
            "gene_name": "SRMS",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q9H3Y6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9H3Y6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9H3Y6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9H3Y6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9HAZ1",
            "gene_name": "CLK4",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q9HAZ1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9HAZ1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9HAZ1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9HAZ1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9I7F7",
            "gene_name": "Ack-like",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q9I7F7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9I7F7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9I7F7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9I7F7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9I7F7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9I7F7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9JJ78",
            "gene_name": "Pbk",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q9JJ78",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JJ78"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9JJ78",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JJ78"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9NR20",
            "gene_name": "DYRK4",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q9NR20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9NR20"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9NR20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9NR20"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9QVP9",
            "gene_name": "Ptk2b",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q9QVP9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9QVP9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9QVP9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9QVP9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9R117",
            "gene_name": "Tyk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q9R117",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9R117"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9R117",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9R117"
                        }
                    ]
                }
            ]
        },
        {
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