{ "uniprot_canonical_ac": "P62911-1", "uniprot_ac": "P62911", "uniprot_id": "RL32_MOUSE", "mass": { "chemical_mass": 15860.0, "monoisotopic_mass": 15860.0 }, "refseq": { "ac": "NP_742083", "name": "large ribosomal subunit protein eL32", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_742083" }, "gene_names": [ { "name": "Rpl32", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P62911", "id": "P62911" }, { "name": "Rpl32", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_742083", "id": "NP_742083" }, { "name": "rpL32-3A", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_742083", "id": "NP_742083" } ], "protein_names": [ { "name": "Large ribosomal subunit protein eL32", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P62911" }, { "name": "60S ribosomal protein L32; snoRNA MBI-141", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_742083", "id": "NP_742083" }, { "name": "60S ribosomal protein L32", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P62911" }, { "name": "large ribosomal subunit protein eL32", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_742083", "id": "NP_742083" } ], "function": [ { "annotation": "Component of the large ribosomal subunit (PubMed:36517592). 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"https://www.reactome.org/PathwayBrowser/#R-MMU-975957", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_742083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_742083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P62911", "url": "https://www.uniprot.org/uniprot/P62911", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P62911-1", "url": "https://www.uniprot.org/uniprot/P62911-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "length": 135, "header": "sp|P62911-1|RL32_MOUSE Isoform 1 of Large ribosomal subunit protein eL32 OS=Mus musculus OX=10090 GN=Rpl32 PE=1 SV=2 CANONICAL=P62911-1" }, "isoforms": [ { "isoform_ac": "P62911-1", "url": "", "sequence": { "sequence": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "length": 135, "header": "sp|P62911-1|RL32_MOUSE Isoform 1 of Large ribosomal subunit protein eL32 OS=Mus musculus OX=10090 GN=Rpl32 PE=1 SV=2 CANONICAL=P62911-1" }, "locus": { "chromosome": "6", "start_pos": 115784858, "end_pos": 115782523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000081840", "url": "https://www.ensembl.org/id/ENSMUST00000081840" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000080523", "url": "https://www.ensembl.org/id/ENSMUSP00000080523" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "P62911", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P62911" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" } ] } ], "phosphorylation": [ { "start_pos": 62, "end_pos": 62, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P62911", "url": "https://www.uniprot.org/uniprot/P62911" } ], "site_lbl": "Ser62" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.", "journal": "Mol. Cell", "date": "2013", "authors": "Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y", "evidence": [ { "database": "UniProtKB", "id": "P62911", "url": "https://www.uniprot.org/uniprot/P62911" } ], "reference": [ { "type": "PubMed", "id": "23806337", "url": "https://glygen.org/publication/PubMed/23806337" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P62911", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P62911" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "The gene family encoding the mouse ribosomal protein L32 contains a uniquely expressed intron-containing gene and an unmutated processed gene.", "journal": "Cell", "date": "1984", "authors": "Perry R.P., Dudov K.P.", "evidence": [ { "database": "UniProtKB", "id": "P62911", "url": "https://www.uniprot.org/uniprot/P62911" } ], "reference": [ { "type": "PubMed", "id": "6327068", "url": "https://glygen.org/publication/PubMed/6327068" } ] } ], "pathway": [ { "id": "mmu:19951", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:19951", "resource": "KEGG Pathway" }, { "id": "R-MMU-156827", "name": "L13a-mediated translational silencing of Ceruloplasmin expression", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-MMU-1799339", "name": "SRP-dependent cotranslational protein targeting to membrane", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-MMU-6791226", "name": "Major pathway of rRNA processing in the nucleolus and cytosol", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-MMU-72689", "name": "Formation of a pool of free 40S subunits", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-MMU-72706", "name": "GTP hydrolysis and joining of the 60S ribosomal subunit", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-MMU-975956", "name": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-MMU-975957", "name": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" } ], "orthologs": [ { "uniprot_canonical_ac": "P04359-1", "protein_name": "Large ribosomal subunit protein eL32", "gene_name": "RpL32", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTIRPAYRPKIVKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRVYCGEIAHGVSSKKRKEIVERAKQLSVRLTNPNGRLRSQENE", "length": 134 }, "evidence": [ { "id": "P62911", "url": "https://omabrowser.org/oma/group/P62911/", "database": "OMA" } ], "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P38061-1", "protein_name": "Large ribosomal subunit protein eL32", "gene_name": "RPL32", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MASLPHPKIVKKHTKKFKRHHSDRYHRVAENWRKQKGIDSVVRRRFRGNISQPKIGYGSNKKTKFLSPSGHKTFLVANVKDLETLTMHTKTYAAEIAHNISAKNRVVILARAKALGIKVTNPKGRLALEA", "length": 130 }, "evidence": [ { "id": "P62911", "url": "https://omabrowser.org/oma/group/P62911/", "database": "OMA" } ], "common_name": "Yeast" }, { "uniprot_canonical_ac": "P62910-1", "protein_name": "Large ribosomal subunit protein eL32", "gene_name": "RPL32", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "length": 135 }, "evidence": [ { "id": "45237335", "url": "http://www.informatics.jax.org/homology/45237335", "database": "MGI" }, { "id": "P62911", "url": "https://omabrowser.org/oma/group/P62911/", "database": "OMA" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "P62912-1", "protein_name": "Large ribosomal subunit protein eL32", "gene_name": "Rpl32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "length": 135 }, "evidence": [ { "id": "45237335", "url": "http://www.informatics.jax.org/homology/45237335", "database": "MGI" }, { "id": "P62911", "url": "https://omabrowser.org/oma/group/P62911/", "database": "OMA" } ], "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P62911", "url": "https://www.uniprot.org/uniprot/P62911" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": 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