{
    "uniprot_canonical_ac": "P60898-1",
    "uniprot_ac": "P60898",
    "uniprot_id": "RPB9_MOUSE",
    "mass": {
        "chemical_mass": 14523.0,
        "monoisotopic_mass": 14523.0
    },
    "refseq": {
        "ac": "NP_081535",
        "name": "DNA-directed RNA polymerase II subunit RPB9",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081535"
    },
    "gene_names": [
        {
            "name": "Polr2i",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P60898",
            "id": "P60898"
        },
        {
            "name": "2810002B19Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081535",
            "id": "NP_081535"
        },
        {
            "name": "Polr2i",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081535",
            "id": "NP_081535"
        }
    ],
    "protein_names": [
        {
            "name": "DNA-directed RNA polymerase II subunit RPB9",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P60898"
        },
        {
            "name": "DNA-directed RNA polymerase II subunit I",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P60898"
        },
        {
            "name": "DNA-directed RNA polymerase II subunit RPB9",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081535",
            "id": "NP_081535"
        },
        {
            "name": "RNA polymerase II 14.5 kDa subunit",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P60898"
        },
        {
            "name": "RNA polymerase II subunit B9",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P60898"
        },
        {
            "name": "RPB14.5; RNA polymerase II subunit B9; DNA-directed RNA polymerase II subunit I; RNA polymerase II 14.5 kDa subunit",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081535",
            "id": "NP_081535"
        },
        {
            "name": "RPB14.5",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P60898"
        }
    ],
    "function": [
        {
            "annotation": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P60898",
                    "url": "https://www.uniprot.org/uniprot/P60898#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "D3YYI3",
                    "url": "https://www.uniprot.org/uniprot/D3YYI3#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "PIRNR005586",
                    "url": "https://www.uniprot.org/uniprot/PIRNR005586#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P60898",
                    "url": "https://www.uniprot.org/uniprot/P60898"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Polr2i",
            "url": "https://www.uniprot.org/uniprot/P60898",
            "locus": {
                "chromosome": "7",
                "start_pos": 29932815,
                "end_pos": 29931373,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000019738",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000019738"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000019738",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000019738",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd10508",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10508",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "69920",
            "url": "https://www.ncbi.nlm.nih.gov/gene/69920",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "P60898",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:P60898*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR001222",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001222",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001529",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001529",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR012164",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012164",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR019761",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019761",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR034012",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR034012",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:69920",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:69920",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1917170",
            "url": "http://www.informatics.jax.org/marker/MGI:1917170",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "DTSMVLF",
            "url": "https://omabrowser.org/oma/group/DTSMVLF/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "19808at2759",
            "url": "http://www.orthodb.org/?query=19808at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11239",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11239",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11239:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11239:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01096",
            "url": "http://pfam.xfam.org/family/PF01096",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF02150",
            "url": "http://pfam.xfam.org/family/PF02150",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_P60898",
            "url": "http://purl.obolibrary.org/obo/PR_P60898",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-112382",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-112382",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-113418",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-113418",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-674695",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-674695",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
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        },
        {
            "id": "R-MMU-6781823",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6781823",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-6782135",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6782135",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
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        },
        {
            "id": "R-MMU-6782210",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6782210",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-6796648",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6796648",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-6803529",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6803529",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-6807505",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6807505",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-72086",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72086",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-72163",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72163",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-72165",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72165",
            "database": "Reactome",
            "categories": [
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        },
        {
            "id": "R-MMU-72203",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72203",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-73776",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-73776",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
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        },
        {
            "id": "R-MMU-73779",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-73779",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-75953",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-75953",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-75955",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-75955",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-76042",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-76042",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-77075",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-77075",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-9018519",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9018519",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_081535",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081535",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3YYI2",
            "url": "https://www.uniprot.org/uniprot/D3YYI2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3YYI2-1",
            "url": "https://www.uniprot.org/uniprot/D3YYI2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3YYI3",
            "url": "https://www.uniprot.org/uniprot/D3YYI3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3YYI3-1",
            "url": "https://www.uniprot.org/uniprot/D3YYI3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3Z3Z8",
            "url": "https://www.uniprot.org/uniprot/D3Z3Z8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3Z3Z8-1",
            "url": "https://www.uniprot.org/uniprot/D3Z3Z8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P60898",
            "url": "https://www.uniprot.org/uniprot/P60898",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P60898-1",
            "url": "https://www.uniprot.org/uniprot/P60898-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE",
        "length": 125,
        "header": "sp|P60898-1|RPB9_MOUSE Isoform 1 of DNA-directed RNA polymerase II subunit RPB9  OS=Mus musculus OX=10090 GN=Polr2i PE=1 SV=1 CANONICAL=P60898-1"
    },
    "isoforms": [
        {
            "isoform_ac": "D3YYI2-1",
            "url": "",
            "sequence": {
                "sequence": "MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYASCWRSDLFVTLLPHALPSAVPELRLPAGSRQQLHLRQQNHARSGRADPDHRRRVPGPHVAPDGGPPVPEVWPQGGSVLSVTQCPS",
                "length": 123,
                "header": "tr|D3YYI2-1|D3YYI2_MOUSE Computationally mapped isoform of Polymerase (RNA) II (DNA directed) polypeptide I  OS=Mus musculus OX=10090 GN=Polr2i PE=1 SV=1 CANONICAL=P60898-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 29932539,
                "end_pos": 29931771,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000108193.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000108193.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000103828.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000103828.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3YYI3-1",
            "url": "",
            "sequence": {
                "sequence": "MLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE",
                "length": 103,
                "header": "tr|D3YYI3-1|D3YYI3_MOUSE Computationally mapped isoform of DNA-directed RNA polymerase subunit  OS=Mus musculus OX=10090 GN=Polr2i PE=1 SV=1 CANONICAL=P60898-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 29932769,
                "end_pos": 29931914,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000108192.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000108192.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000103827.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000103827.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3Z3Z8-1",
            "url": "",
            "sequence": {
                "sequence": "MLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAE",
                "length": 83,
                "header": "tr|D3Z3Z8-1|D3Z3Z8_MOUSE Computationally mapped isoform of Polymerase (RNA) II (DNA directed) polypeptide I  OS=Mus musculus OX=10090 GN=Polr2i PE=1 SV=1 CANONICAL=P60898-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 29932543,
                "end_pos": 29931914,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000149654.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000149654.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000116741.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000116741.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "P60898-1",
            "url": "",
            "sequence": {
                "sequence": "MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE",
                "length": 125,
                "header": "sp|P60898-1|RPB9_MOUSE Isoform 1 of DNA-directed RNA polymerase II subunit RPB9  OS=Mus musculus OX=10090 GN=Polr2i PE=1 SV=1 CANONICAL=P60898-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 29932769,
                "end_pos": 29931771,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000019882",
                        "url": "https://www.ensembl.org/id/ENSMUST00000019882"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000019882",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000019882"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:69920",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:69920",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-112382",
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            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-112382",
            "resource": "Reactome",
            "description": "Formation of RNA Pol II elongation complex"
        },
        {
            "id": "R-MMU-113418",
            "name": "Formation of the Early Elongation Complex",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-113418",
            "resource": "Reactome",
            "description": "Formation of the Early Elongation Complex"
        },
        {
            "id": "R-MMU-674695",
            "name": "RNA Polymerase II Pre-transcription Events",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-674695",
            "resource": "Reactome",
            "description": "RNA Polymerase II Pre-transcription Events"
        },
        {
            "id": "R-MMU-6781823",
            "name": "Formation of TC-NER Pre-Incision Complex",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6781823",
            "resource": "Reactome",
            "description": "Formation of TC-NER Pre-Incision Complex"
        },
        {
            "id": "R-MMU-6782135",
            "name": "Dual incision in TC-NER",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6782135",
            "resource": "Reactome",
            "description": "Dual incision in TC-NER"
        },
        {
            "id": "R-MMU-6782210",
            "name": "Gap-filling DNA repair synthesis and ligation in TC-NER",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6782210",
            "resource": "Reactome",
            "description": "Gap-filling DNA repair synthesis and ligation in TC-NER"
        },
        {
            "id": "R-MMU-6796648",
            "name": "TP53 Regulates Transcription of DNA Repair Genes",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6796648",
            "resource": "Reactome",
            "description": "TP53 Regulates Transcription of DNA Repair Genes"
        },
        {
            "id": "R-MMU-6803529",
            "name": "FGFR2 alternative splicing",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6803529",
            "resource": "Reactome",
            "description": "FGFR2 alternative splicing"
        },
        {
            "id": "R-MMU-6807505",
            "name": "RNA polymerase II transcribes snRNA genes",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6807505",
            "resource": "Reactome",
            "description": "RNA polymerase II transcribes snRNA genes"
        },
        {
            "id": "R-MMU-72086",
            "name": "mRNA Capping",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72086",
            "resource": "Reactome",
            "description": "mRNA Capping"
        },
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            "id": "R-MMU-72163",
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