{ "uniprot_canonical_ac": "P53534-1", "uniprot_ac": "P53534", "uniprot_id": "PYGB_RAT", "mass": { "chemical_mass": 96174.0, "monoisotopic_mass": 96174.0 }, "refseq": { "ac": "NP_037320", "name": "glycogen phosphorylase, brain form", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320" }, "gene_names": [ { "name": "Pygb", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P53534", "id": "P53534" }, { "name": "GLYPHOA", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320", "id": "NP_037320" }, { "name": "Pygb", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320", "id": "NP_037320" } ], "protein_names": [ { "name": "Glycogen phosphorylase, brain form", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P53534" }, { "name": "2.4.1.1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P53534" }, { "name": "brain glycogen phosphorylase; phosphorylase, glycogen; brain", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320", "id": "NP_037320" }, { "name": "glycogen phosphorylase, brain form", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320", "id": "NP_037320" } ], "function": [ { "annotation": "Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8I6G9W3", "url": "https://www.uniprot.org/uniprot/A0A8I6G9W3#function" }, { "database": "UniProtKB", "id": "RU000587", "url": "https://www.uniprot.org/uniprot/RU000587#function" }, { "database": "UniProtKB", "id": "G3V6Y6", "url": "https://www.uniprot.org/uniprot/G3V6Y6#function" }, { "database": "UniProtKB", "id": "A0A8I6GKE5", "url": "https://www.uniprot.org/uniprot/A0A8I6GKE5#function" } ] }, { "annotation": "Glycogen phosphorylase that regulates glycogen mobilization (By similarity). Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534#function" }, { "database": "PubMed", "id": "7916624", "url": "https://glygen.org/publication/PubMed/7916624" }, { "database": "UniProtKB", "id": "P11216", "url": "https://www.uniprot.org/uniprot/P11216#function" } ] }, { "annotation": "Thus, glycogen is an active fuel for specific structures in normal activated brain, not simply an emergency fuel depot and flux-generated pyruvate greatly exceeded net accumulation of lactate or net consumption of glycogen during activation. T", "evidence": [ { "database": "RefSeq", "id": "NP_037320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320" }, { "database": "PubMed", "id": "17442042", "url": "https://glygen.org/publication/PubMed/17442042" } ] }, { "annotation": "We have demonstrated immunocytochemically the presence of glycogen phosphorylase, brain form in large and small axons of the rat vagus nerve, but not in Schwann cells.", "evidence": [ { "database": "RefSeq", "id": "NP_037320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320" }, { "database": "PubMed", "id": "16879805", "url": "https://glygen.org/publication/PubMed/16879805" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "common_name": "Rat" } ], "gene": [ { "name": "Pygb", "url": "https://www.uniprot.org/uniprot/P53534", "locus": { "chromosome": "3", "start_pos": 139663553, "end_pos": 139611749, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000007583", "url": "https://www.ensembl.org/id/ENSRNOG00000007583" } ] } } ], "crossref": [ { "id": "ENSRNOG00000007583", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000007583", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "GT35", "url": "http://www.cazy.org/GT35.html", "database": "CAZy", "categories": [ "Protein Classification" ] }, { "id": "cd04300", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04300", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "25739", "url": "https://www.ncbi.nlm.nih.gov/gene/25739", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P53534", "url": "https://www.ebi.ac.uk/intact/interactors/id:P53534*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:25739", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:25739", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "P53534", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P53534", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "WLKQANP", "url": "https://omabrowser.org/oma/group/WLKQANP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5473321at2759", "url": "http://www.orthodb.org/?query=5473321at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11468", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11468", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11468:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11468:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00343", "url": "http://pfam.xfam.org/family/PF00343", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6798695", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_037320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "3460", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=3460", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "41732", "url": "https://www.rhea-db.org/rhea/41732", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8I6G9W3", "url": "https://www.uniprot.org/uniprot/A0A8I6G9W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6G9W3-1", "url": "https://www.uniprot.org/uniprot/A0A8I6G9W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GKE5", "url": "https://www.uniprot.org/uniprot/A0A8I6GKE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GKE5-1", "url": "https://www.uniprot.org/uniprot/A0A8I6GKE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3V6Y6", "url": "https://www.uniprot.org/uniprot/G3V6Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3V6Y6-1", "url": "https://www.uniprot.org/uniprot/G3V6Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P53534-1", "url": "https://www.uniprot.org/uniprot/P53534-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKPLTDSERQKQISVRGIAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPNGVLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLAEIIVERIGEGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYKVKINPCSMFDVHVKRIHEYKRQLLNCLHIITLYNRIKKDPTKTFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAQEFYERLPELRQAVDQISSGFFSPKDPDCFKDVVNMLMYHDRFKVFADYEAYIQCQAQVDHLYRNPKDWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPP", "length": 838, "header": "sp|P53534-1|PYGB_RAT Isoform 1 of Glycogen phosphorylase, brain form OS=Rattus norvegicus OX=10116 GN=Pygb PE=1 SV=3 CANONICAL=P53534-1" }, "isoforms": [ { "isoform_ac": "A0A8I6G9W3-1", "url": "", "sequence": { "sequence": "MAKPLTDSERQKQISVRGIAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPNGVLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLAEIIVERIGEGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYKVKINPASMFDVHVKRIHEYKRQLLNCLHIITLYNRIKKDPTKTFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAREFYERLPELRQAVDQISSGFFSPKDPDCFKDVVNMLMYHDRIPRIGLKR", "length": 775, "header": "tr|A0A8I6G9W3-1|A0A8I6G9W3_RAT Computationally mapped isoform of Alpha-1,4 glucan phosphorylase OS=Rattus norvegicus OX=10116 GN=Pygb PE=1 SV=1 CANONICAL=P53534-1" }, "locus": { "chromosome": "3", "start_pos": 139657176, "end_pos": 139611833, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000100727.1", "url": "https://www.ensembl.org/id/ENSRNOT00000100727.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000084107.1", "url": "https://www.ensembl.org/id/ENSRNOP00000084107.1" } ] } }, { "isoform_ac": "A0A8I6GKE5-1", "url": "", "sequence": { "sequence": "MAKPLTDSERQKQISVRGIAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPNGVLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLAEIIVERIGEGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYKVKINPASMFDVHVKRIHEYKRQLLNCLHIITLYNRIKKDPTKTFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAREFYERLPELRQAVDQISSGFFSPKDPDCFKDVVNMLMYHDRFKVFADYEAYIQCQAQVDHLYRTEQRSALDPDVGPIGHQAPGKMQTHVTGSRLHDTVGRACFPTLPA", "length": 838, "header": "tr|A0A8I6GKE5-1|A0A8I6GKE5_RAT Computationally mapped isoform of Alpha-1,4 glucan phosphorylase OS=Rattus norvegicus OX=10116 GN=Pygb PE=1 SV=1 CANONICAL=P53534-1" }, "locus": { "chromosome": "3", "start_pos": 139662008, "end_pos": 139611833, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000111537.1", "url": "https://www.ensembl.org/id/ENSRNOT00000111537.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000093697.1", "url": "https://www.ensembl.org/id/ENSRNOP00000093697.1" } ] } }, { "isoform_ac": "G3V6Y6-1", "url": "", "sequence": { "sequence": "MAKPLTDSERQKQISVRGIAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPNGVLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLAEIIVERIGEGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYKVKINPASMFDVHVKRIHEYKRQLLNCLHIITLYNRIKKDPTKTFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAREFYERLPELRQAVDQISSGFFSPKDPDCFKDVVNMLMYHDRFKVFADYEAYIQCQAQVDHLYRNPKDWTKKTEQRSALDPDVGPIGHQAPGKMQTHVTGSRLHDTVGRACFPTLPA", "length": 846, "header": "tr|G3V6Y6-1|PYGB_RAT Computationally mapped isoform of Glycogen phosphorylase, brain form OS=Rattus norvegicus OX=10116 GN=Pygb PE=1 SV=2 CANONICAL=P53534-1" }, "locus": { "chromosome": "3", "start_pos": 139662008, "end_pos": 139611833, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000010157.7", "url": "https://www.ensembl.org/id/ENSRNOT00000010157.7" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000010158.6", "url": "https://www.ensembl.org/id/ENSRNOP00000010158.6" } ] } }, { "isoform_ac": "P53534-1", "url": "", "sequence": { "sequence": "MAKPLTDSERQKQISVRGIAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPNGVLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLAEIIVERIGEGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYKVKINPCSMFDVHVKRIHEYKRQLLNCLHIITLYNRIKKDPTKTFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAQEFYERLPELRQAVDQISSGFFSPKDPDCFKDVVNMLMYHDRFKVFADYEAYIQCQAQVDHLYRNPKDWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPP", "length": 838, "header": "sp|P53534-1|PYGB_RAT Isoform 1 of Glycogen phosphorylase, brain form OS=Rattus norvegicus OX=10116 GN=Pygb PE=1 SV=3 CANONICAL=P53534-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "P53534", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P53534" }, { "id": "18683930", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18683930" }, { "id": "34502162", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34502162" } ] } ], "phosphorylation": [ { "start_pos": 15, "end_pos": 15, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "P53534", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53534" } ], "site_lbl": "Ser15" }, { "start_pos": 197, "end_pos": 197, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "site_lbl": "Tyr197" }, { "start_pos": 473, "end_pos": 473, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "site_lbl": "Tyr473" }, { "start_pos": 524, "end_pos": 524, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "P53534", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53534" } ], "site_lbl": "Ser524" } ], "glycation": [], "keywords": [ "enzyme", "glycosyltransferase-activity", "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Immunocytochemical analysis of rat vagus nerve by antibodies against glycogen phosphorylase isozymes.", "journal": "Brain research", "date": "2006", "authors": "Pfeiffer-Guglielmi B, Coles JA, Francke M, Reichenbach A, Fleckenstein B, Jung G, Nicaise G, Hamprecht B", "evidence": [ { "database": "RefSeq", "id": "NP_037320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320" } ], "reference": [ { "type": "PubMed", "id": "16879805", "url": "https://glygen.org/publication/PubMed/16879805" } ] }, { "title": "A glycogen phosphorylase inhibitor selectively enhances local rates of glucose utilization in brain during sensory stimulation of conscious rats: implications for glycogen turnover.", "journal": "Journal of neurochemistry", "date": "2007", "authors": "Dienel GA, Ball KK, Cruz NF", "evidence": [ { "database": "RefSeq", "id": "NP_037320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037320" } ], "reference": [ { "type": "PubMed", "id": "17442042", "url": "https://glygen.org/publication/PubMed/17442042" } ] }, { "title": "Direct in-gel fluorescence detection and cellular imaging of O-GlcNAc-modified proteins.", "journal": "Journal of the American Chemical Society", "date": "2008", "authors": "Clark PM, Dweck JF, Mason DE, Hart CR, Buck SB, Peters EC, Agnew BJ, Hsieh-Wilson LC", "evidence": [ { "database": "O-GlcNAc Database", "id": "P53534", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P53534" } ], "reference": [ { "type": "PubMed", "id": "18683930", "url": "https://glygen.org/publication/PubMed/18683930" } ] }, { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nature communications", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" }, { "database": "UniProtKB", "id": "G3V6Y6", "url": "https://www.uniprot.org/uniprot/G3V6Y6" }, { "database": "iPTMnet", "id": "P53534", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53534" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "title": "Studies on the expression and evolution of the glycogen phosphorylase gene family in the rat.", "journal": "Genome", "date": "1988", "authors": "Hudson J.W., Crerar M.M., David E.S., Golding G.B., Matthews K.E.", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "reference": [ { "type": "PubMed", "id": "3209063", "url": "https://glygen.org/publication/PubMed/3209063" } ] }, { "title": "An O-GlcNAcylomic Approach Reveals ACLY as a Potential Target in Sepsis in the Young Rat.", "journal": "International journal of molecular sciences", "date": "2021", "authors": "Denis M, Dupas T, Persello A, Dontaine J, Bultot L, Betus C, Pele T, Dhot J, Erraud A, Maillard A, Montnach J, Leroux AA, Bigot-Corbel E, Vertommen D, Riviere M, Lebreton J, Tessier A, Waard M, Bertrand L, Rozec B, Lauzier B", "evidence": [ { "database": "O-GlcNAc Database", "id": "P53534", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P53534" } ], "reference": [ { "type": "PubMed", "id": "34502162", "url": "https://glygen.org/publication/PubMed/34502162" } ] }, { "title": "Comparative analysis of species-independent, isozyme-specific amino-acid substitutions in mammalian muscle, brain and liver glycogen phosphorylases.", "journal": "Biochim. Biophys. Acta", "date": "1993", "authors": "Hudson J.W., Crerar M.M., Hefferon K.L.", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "reference": [ { "type": "PubMed", "id": "7916624", "url": "https://glygen.org/publication/PubMed/7916624" } ] } ], "pathway": [ { "id": "rno:25739", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:25739", "resource": "KEGG Pathway" }, { "id": "R-RNO-6798695", "name": "Neutrophil degranulation", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "P11216-1", "protein_name": "Glycogen phosphorylase, brain form", "gene_name": "PYGB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNIPRD", "length": 843 }, "evidence": [ { "id": "45226444", "url": "http://www.informatics.jax.org/homology/45226444", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CI94-1", "protein_name": "Glycogen phosphorylase, brain form", "gene_name": "Pygb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKPLTDSERQKQISVRGIAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSRFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLAEIIVERIGEGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYKVKINPASMFDVHVKRIHEYKRQLLNCLHIITLYNRIKKDPAKAFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAREFYERLPELRQAVDQISSGFFSPKDPDCFKDVVNMLMYHDRFKVFADYEAYIQCQAQVDRLYRNSKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNLPKD", "length": 843 }, "evidence": [ { "id": "45226444", "url": "http://www.informatics.jax.org/homology/45226444", "database": "MGI" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" }, { "name": "organic cyclic compound binding", "id": "GO:0097159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097159", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" }, { "name": "glycogen phosphorylase activity", "id": "GO:0008184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008184", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" }, { "name": "linear malto-oligosaccharide phosphorylase activity", "id": "GO:0102250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102250", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" }, { "name": "SHG alpha-glucan phosphorylase activity", "id": "GO:0102499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102499", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycogen metabolic process", "id": "GO:0005977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" }, { "name": "glycogen catabolic process", "id": "GO:0005980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005980", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A.", "evidence": [ { "database": "UniProtKB", "id": "P53534", "url": "https://www.uniprot.org/uniprot/P53534" }, { "database": "PubMed", "id": "P11217", "url": "https://glygen.org/publication/PubMed/P11217" } ] } ], "interactions": [], "reactions": [ { "id": "41732", "name": "", "equation": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53534-1", "P09811-1", "P09812-1", "P11216-1", "P06737-1", "P11217-1", "Q8CI94-1", "Q9WUB3-1", "Q9ET01-1", "P06738-1", "P34114-1", "Q00766-1", "Q9XTL9-1" ], "evidence": [ { "id": "41732", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41732" } ] }, { "id": "R-RNO-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, azurophil granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3MIE4-1", "P09215-1", "P63086-1", "O35244-1", "P16638-1", "P50430-1", "P53534-1", "P46462-1", "D3ZZC1-1", "Q32KJ5-1", "D3ZUM4-1", "P06760-1", "P07824-1", "P30919-1", "P80067-1", "D3ZLZ7-1", "P00697-1", "P20070-1", "P20717-1", "Q6XQN1-1", "D4AE56-1", "P70709-1", "Q62662-1", "Q66H71-1", "Q6AYS4-1", "P00762-1", "P00763-1", "P17164-1", "Q62867-1", "Q9EPB1-1", "Q32KJ6-1", "Q6AXR4-1", "D3ZJF9-1" ], "evidence": [ { "id": "R-RNO-6798751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6798751" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "D3ZJF9", "gene_name": "Gla", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "D3ZJF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZJF9" } ] } ] }, { "uniprot_ac": "D3ZLZ7", "gene_name": "Impdh1", "activity": [ { "ec_number": "1.1.1.205", "activity": "H2O + IMP + NAD(+) = H(+) + NADH + XMP.", "evidence": [ { "id": "D3ZLZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZLZ7" } ] }, { "ec_number": "1.1.1.205", "activity": "", "evidence": [ { "id": "D3ZLZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZLZ7" } ] } ] }, { "uniprot_ac": "D3ZUM4", "gene_name": "Glb1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "D3ZUM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZUM4" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "D3ZUM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZUM4" } ] } ] }, { "uniprot_ac": "D3ZZC1", "gene_name": "Txndc5", "activity": [ { "ec_number": "5.3.4.1", "activity": "Catalyzes the rearrangement of -S-S- bonds in proteins.", "evidence": [ { "id": "D3ZZC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZZC1" } ] }, { "ec_number": "5.3.4.1", "activity": "", "evidence": [ { "id": "D3ZZC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZZC1" } ] } ] }, { "uniprot_ac": "D4AE56", "gene_name": "Ptges2", "activity": [ { "ec_number": "5.3.99.3", "activity": "prostaglandin H2 = prostaglandin E2.", "evidence": [ { "id": "D4AE56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE56" } ] }, { "ec_number": "5.3.99.3", "activity": "", "evidence": [ { "id": "D4AE56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE56" } ] } ] }, { "uniprot_ac": "O35244", "gene_name": "Prdx6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "O35244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35244" } ] }, { "ec_number": "3.1.1.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "O35244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35244" } ] }, { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "O35244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35244" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "O35244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35244" } ] } ] }, { "uniprot_ac": "P00697", "gene_name": "Lyz1", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P00697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00697" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P00697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00697" } ] } ] }, { "uniprot_ac": "P00762", "gene_name": "Prss1", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "P00762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00762" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "P00762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00762" } ] } ] }, { "uniprot_ac": "P00763", "gene_name": "Prss2", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "P00763", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00763" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "P00763", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00763" } ] } ] }, { "uniprot_ac": "P06737", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "P06737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06737" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "P06737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06737" } ] } ] }, { "uniprot_ac": "P06738", "gene_name": "GPH1", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "P06738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06738" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "P06738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06738" } ] } ] }, { "uniprot_ac": "P06760", "gene_name": "Gusb", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate.", "evidence": [ { "id": "P06760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06760" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "P06760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06760" } ] } ] }, { "uniprot_ac": "P07824", "gene_name": "Arg1", "activity": [ { "ec_number": "3.5.3.1", "activity": "H2O + L-arginine = L-ornithine + urea.", "evidence": [ { "id": "P07824", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07824" } ] }, { "ec_number": "3.5.3.1", "activity": "", "evidence": [ { "id": "P07824", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07824" } ] } ] }, { "uniprot_ac": "P09215", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09215" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09215" } ] } ] }, { "uniprot_ac": "P09811", "gene_name": "Pygl", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "P09811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09811" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "P09811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09811" } ] } ] }, { "uniprot_ac": "P09812", "gene_name": "Pygm", "activity": [ { "ec_number": "2.4.1.1", "activity": 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